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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q3 2025

Institutional positions in Wave Life Sciences, Inc. as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
189
+14 vs. Q2 2025
Shares held
143.7M
+4.85M (+3.5%) vs. Q2 2025
Total value
$1.05B
+$149.2M (+16.5%) vs. Q2 2025
New holders
32
61 more added
Sold out
18
62 more reduced

2 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 189 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ3 2025: $1.05B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q2 2025.

Institutions holding WVE in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
CWM, LLC31$00.00%00.0%Unchanged
Covestor Ltd13$00.00%00.0%Unchanged
Truvestments Capital LLC2$130.00%00.0%Unchanged
True Wealth Design, LLC37$2710.00%00.0%Unchanged
American National Bank50$3660.00%00.0%Unchanged
Principal Securities, Inc.58$4250.00%00.0%Unchanged
Montag A & Associates Inc59$4320.00%+59New
Parkside Financial Bank & Trust72$5280.00%00.0%Unchanged
Parallel Advisors, LLC95$6950.00%00.0%Unchanged
ORG Partners LLC100$7320.00%+100New
SBI Securities Co., Ltd.105$7690.00%+31+41.9%Added
Versant Capital Management, Inc108$7910.00%+108New
Allworth Financial LP124$9080.00%00.0%Unchanged
EverSource Wealth Advisors, LLC200$1.46K0.00%−2−1.0%Reduced
Rothschild Investment LLC245$1.79K0.00%−55−18.3%Reduced
Smartleaf Asset Management LLC301$2.15K0.00%+301New
Signaturefd, LLC310$2.27K0.00%00.0%Unchanged
The PNC Financial Services Group, Inc.323$2.36K0.00%+63+24.2%Added
Steward Partners Investment Advisory, LLC400$2.93K0.00%−800−66.7%Reduced
GAMMA Investing LLC441$3.23K0.00%−75−14.5%Reduced
Daiwa Securities Group Inc.503$4.00K0.00%00.0%Unchanged
Larson Financial Group LLC692$5.07K0.00%−736−51.5%Reduced
Massmutual Trust Co FSB728$5.33K0.00%+389+114.7%Added
Point72 (DIFC) Ltd752$5.51K0.00%+752New
Advisor Group Holdings, Inc.981$7.29K0.00%−1,077−52.3%Reduced
Optiver Holding B.V.1,000$7.32K0.00%+1,000New
Walleye Trading LLC1,065$7.80K0.00%+1,065New
Simplex Trading, LLC1,206$8.00K0.00%−45,024−97.4%Reduced
Sterling Capital Management LLC1,126$8.24K0.00%+513+83.7%Added
Wealthspire Advisors, LLC1,350$9.88K0.00%+1,350New
Farther Finance Advisors, LLC1,570$11.5K0.00%+59+3.9%Added
Nisa Investment Advisors, LLC1,576$11.5K0.00%00.0%Unchanged
Federation des caisses Desjardins du Quebec2,350$17.2K0.00%00.0%Unchanged
Quadrant Capital Group LLC2,396$17.5K0.00%+2,396New
Ancora Advisors, LLC3,000$22.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)3,197$23.4K0.00%−8,461−72.6%Reduced
Amalgamated Bank3,328$24.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.3,424$25.1K0.00%−481−12.3%Reduced
Point72 Hong Kong Ltd4,753$34.8K0.00%+4,753New
Mirae Asset Global Investments Co., Ltd.6,152$45.0K0.00%+198+3.3%Added
US Bancorp7,688$56.3K0.00%+358+4.9%Added
Ameritas Investment Partners, Inc.9,364$68.5K0.00%−2,080−18.2%Reduced
Bessemer Group Inc9,925$72.0K0.00%+9,135+1,156.3%Added
Russell Investments Group, Ltd.9,928$72.7K0.00%+9,284+1,441.6%Added
Capstone Investment Advisors, LLC10,406$76.2K0.00%+10,406New
AQR Capital Management LLC10,698$78.3K0.00%+10,698New
Chicago Partners Investment Group LLC10,572$80.2K0.00%−1,693−13.8%Reduced
HSBC Holdings PLC11,167$81.7K0.00%+11,167New
Wolverine Trading, LLC11,803$84.2K0.00%+11,803New
NJ State Employees Deferred Compensation Plan11,700$85.6K0.01%00.0%Unchanged
Verdence Capital Advisors LLC11,307$86.2K0.00%+11,307New
Creative Planning11,870$86.9K0.00%+386+3.4%Added
CIBC Bancorp USA Inc.11,948$87.5K0.00%+11,948New
Caption Management, LLC12,000$87.8K0.01%+12,000New
HighTower Advisors, LLC12,164$89.0K0.00%+12,164New
Prudential Financial Inc12,375$90.6K0.00%+55+0.4%Added
Matisse Capital13,193$96.6K0.04%+2,000+17.9%Added
Kraematon Investment Advisors, Inc13,450$98.5K0.08%−5,910−30.5%Reduced
Marshall Wace, LLP14,000$102.5K0.00%−10,828−43.6%Reduced
Victory Capital Management Inc14,632$107.1K0.00%−45−0.3%Reduced
Velan Capital Investment Management LP15,000$109.8K0.10%00.0%Unchanged
Cresset Asset Management, LLC15,024$110.0K0.00%+15,024New
Raymond James Financial Inc15,687$114.8K0.00%−1,117−6.6%Reduced
Pictet Asset Management Holding SA15,726$115.1K0.00%−653−4.0%Reduced
Virtus Investment Advisers, Inc.15,804$115.7K0.03%+2,744+21.0%Added
Martingale Asset Management L P16,252$119.0K0.00%−14,160−46.6%Reduced
Rafferty Asset Management, LLC16,621$121.7K0.00%+3,138+23.3%Added
State Board of Administration of Florida Retirement System16,950$124.1K0.00%00.0%Unchanged
Sig Brokerage, LP17,971$131.5K0.03%+17,971New
Balyasny Asset Management LLC18,427$134.9K0.00%+18,427New
KLP Kapitalforvaltning AS20,800$152.3K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA23,622$172.9K0.00%−48,837−67.4%Reduced
Profund Advisors LLC24,722$181.0K0.01%+2,215+9.8%Added
ProShare Advisors LLC24,835$181.8K0.00%−3,904−13.6%Reduced
Brinker Capital Investments, LLC25,415$186.0K0.00%+1,023+4.2%Added
Teacher Retirement System of Texas26,598$194.7K0.00%−2,357−8.1%Reduced
Engineers Gate Manager LP27,489$201.2K0.00%−16,924−38.1%Reduced
Police & Firemen's Retirement System of New Jersey31,033$227.2K0.00%+5,244+20.3%Added
Arizona State Retirement System32,190$235.6K0.00%+836+2.7%Added
Citigroup Inc34,513$252.6K0.00%−63,562−64.8%Reduced
Inceptionr LLC34,643$253.6K0.06%+17,026+96.6%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.36,169$264.8K0.00%+72+0.2%Added
Envestnet Asset Management Inc39,847$291.7K0.00%+2,866+7.7%Added
Omers Administration Corp40,000$292.8K0.00%+40,000New
Fox Run Management, L.L.C.41,988$307.4K0.05%+41,988New
Group One Trading, L.P.43,379$317.5K0.01%+39,599+1,047.6%Added
Graham Capital Management, L.P.43,946$321.7K0.01%+43,946New
Glenmede Investment Management, LP44,326$324.5K0.00%−8,695−16.4%Reduced
Quantinno Capital Management LP45,049$329.8K0.00%+45,049New
Intech Investment Management LLC45,888$335.9K0.00%−20,306−30.7%Reduced
Sphera Funds Management Ltd.50,000$366.0K0.09%+50,000New
Handelsbanken Fonder AB50,800$372.0K0.00%00.0%Unchanged
Gsa Capital Partners LLP51,198$375.0K0.03%+51,198New
Janus Henderson Group PLC51,700$378.7K0.00%00.0%Unchanged
Zurcher Kantonalbank (Zurich Cantonalbank)52,046$381.0K0.00%−257−0.5%Reduced
SummitTX Capital, L.P.53,611$392.4K0.02%+53,611New
State of Wisconsin Investment Board59,131$432.8K0.00%+13,673+30.1%Added
MetLife Investment Management59,206$433.4K0.00%−8,051−12.0%Reduced
HighVista Strategies LLC59,261$433.8K0.11%+23,303+64.8%Added
Franklin Resources Inc62,259$455.7K0.00%+277+0.4%Added