Wave Life Sciences, Inc.
WVE- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001631574
In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.
13F holders, Q4 2025
Institutional positions in Wave Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 219
- +35 vs. Q3 2025
- Shares held
- 182.7M
- +39.1M (+27.3%) vs. Q3 2025
- Total value
- $3.11B
- +$2.06B (+195.7%) vs. Q3 2025
- New holders
- 73
- 79 more added
- Sold out
- 38
- 47 more reduced
5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 239 | $1.06B |
| Q1 2026 | 232 | $1.25B |
| Q4 2025 | 219 | $3.11B |
| Q3 2025 | 189 | $1.05B |
| Q2 2025 | 177 | $903.1M |
| Q1 2025 | 197 | $1.06B |
| Q4 2024 | 184 | $1.59B |
| Q3 2024 | 162 | $986.1M |
| Q2 2024 | 144 | $474.4M |
| Q1 2024 | 132 | $572.3M |
| Q4 2023 | 115 | $468.0M |
| Q3 2023 | 85 | $417.4M |
| Q2 2023 | 81 | $262.7M |
| Q1 2023 | 73 | $303.5M |
| Q4 2022 | 75 | $476.9M |
| Q3 2022 | 61 | $242.8M |
| Q2 2022 | 60 | $220.3M |
| Q1 2022 | 82 | $95.4M |
| Q4 2021 | 90 | $148.5M |
| Q3 2021 | 88 | $183.5M |
| Q2 2021 | 87 | $246.7M |
| Q1 2021 | 102 | $214.8M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Prelude Capital Management, LLC | 93,202 | $1.58M | 0.12% | +93,202 | New |
| Knott David M Jr | 90,000 | $1.53M | 0.71% | 00.0% | Unchanged |
| Prescott Group Capital Management, L.L.C. | 90,000 | $1.53M | 0.14% | +90,000 | New |
| State of Wisconsin Investment Board | 87,141 | $1.48M | 0.00% | +28,010+47.4% | Added |
| Ikarian Capital, LLC | 85,285 | $1.45M | 0.19% | −10,670−11.1% | Reduced |
| BNP Paribas Arbitrage, SA | 82,022 | $1.39M | 0.00% | +58,400+247.2% | Added |
| a16z Perennial Management, L.P. | 77,619 | $1.32M | 0.10% | 00.0% | Unchanged |
| Connor, Clark & Lunn Investment Management Ltd. | 69,078 | $1.17M | 0.00% | +69,078 | New |
| Group One Trading, L.P. | 67,969 | $1.16M | 0.03% | +24,590+56.7% | Added |
| SG Americas Securities, LLC | 67,031 | $1.14M | 0.00% | +67,031 | New |
| MetLife Investment Management | 64,763 | $1.10M | 0.01% | +5,557+9.4% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 62,729 | $1.07M | 0.00% | +10,683+20.5% | Added |
| Cinctive Capital Management LP | 61,831 | $1.05M | 0.06% | −48,706−44.1% | Reduced |
| Handelsbanken Fonder AB | 54,700 | $930.0K | 0.00% | +3,900+7.7% | Added |
| SEI Investments Co | 54,457 | $925.8K | 0.00% | −17,798−24.6% | Reduced |
| J. Goldman & Co LP | 53,762 | $914.0K | 0.04% | +53,762 | New |
| Janus Henderson Group PLC | 51,700 | $877.6K | 0.00% | 00.0% | Unchanged |
| Russell Investments Group, Ltd. | 49,903 | $848.4K | 0.00% | +39,975+402.6% | Added |
| Sig Brokerage, LP | 48,384 | $822.5K | 0.28% | +30,413+169.2% | Added |
| Citigroup Inc | 46,759 | $794.9K | 0.00% | +12,246+35.5% | Added |
| Glenmede Trust Co NA | 42,732 | $726.4K | 0.00% | +42,732 | New |
| Matisse Capital | 42,193 | $717.3K | 0.32% | +29,000+219.8% | Added |
| Gainplan LLC | 39,972 | $679.5K | 0.26% | +39,972 | New |
| Envestnet Asset Management Inc | 39,820 | $676.9K | 0.00% | −27−0.1% | Reduced |
| China Universal Asset Management Co., Ltd. | 39,742 | $675.6K | 0.05% | −38,153−49.0% | Reduced |
| Quantinno Capital Management LP | 38,925 | $661.7K | 0.00% | −6,124−13.6% | Reduced |
| State of New Jersey Common Pension Fund D | 38,022 | $646.4K | 0.00% | +38,022 | New |
| New York State Common Retirement Fund | 35,920 | $610.6K | 0.00% | −71,126−66.4% | Reduced |
| Walleye Trading LLC | 33,241 | $565.1K | 0.01% | +32,176+3,021.2% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 33,839 | $539.7K | 0.00% | −2,330−6.4% | Reduced |
| Man Group plc | 31,418 | $534.1K | 0.00% | −101,353−76.3% | Reduced |
| PSP Research LLC | 31,040 | $527.7K | 0.46% | +31,040 | New |
| Police & Firemen's Retirement System of New Jersey | 31,033 | $527.6K | 0.00% | 00.0% | Unchanged |
| Intech Investment Management LLC | 30,667 | $521.3K | 0.00% | −15,221−33.2% | Reduced |
| Arizona State Retirement System | 30,645 | $521.0K | 0.00% | −1,545−4.8% | Reduced |
| Entropy Technologies, LP | 30,613 | $520.4K | 0.03% | +30,613 | New |
| Vestmark Advisory Solutions, Inc. | 30,421 | $517.2K | 0.01% | +30,421 | New |
| ProShare Advisors LLC | 28,536 | $485.1K | 0.00% | +3,701+14.9% | Added |
| AlphaCentric Advisors LLC | 27,590 | $469.0K | 0.47% | +27,590 | New |
| Virtu Financial LLC | 26,889 | $457.0K | 0.02% | +26,889 | New |
| Exchange Traded Concepts, LLC | 25,615 | $435.5K | 0.00% | +25,615 | New |
| Brinker Capital Investments, LLC | 25,030 | $425.5K | 0.00% | −385−1.5% | Reduced |
| KLP Kapitalforvaltning AS | 24,000 | $408.0K | 0.00% | +3,200+15.4% | Added |
| Royal Bank of Canada | 23,206 | $396.0K | 0.00% | −147,292−86.4% | Reduced |
| HighTower Advisors, LLC | 22,830 | $388.1K | 0.00% | +10,666+87.7% | Added |
| Allianz Asset Management GmbH | 22,000 | $374.0K | 0.00% | +22,000 | New |
| Simplex Trading, LLC | 21,126 | $359.1K | 0.01% | +19,920+1,651.7% | Added |
| Advisory Services Network, LLC | 20,900 | $355.3K | 0.01% | +20,900 | New |
| Persistent Asset Partners Ltd | 19,827 | $337.1K | 0.16% | +19,827 | New |
| FORA Capital, LLC | 19,194 | $326.3K | 0.04% | +19,194 | New |
| Creative Planning | 18,121 | $308.1K | 0.00% | +6,251+52.7% | Added |
| Cresset Asset Management, LLC | 17,929 | $304.8K | 0.00% | +2,905+19.3% | Added |
| HSBC Holdings PLC | 16,990 | $290.9K | 0.00% | +5,823+52.1% | Added |
| State Board of Administration of Florida Retirement System | 16,950 | $288.1K | 0.00% | 00.0% | Unchanged |
| Teacher Retirement System of Texas | 16,443 | $279.5K | 0.00% | −10,155−38.2% | Reduced |
| Virtus Investment Advisers, Inc. | 16,064 | $273.1K | 0.07% | +260+1.6% | Added |
| Victory Capital Management Inc | 15,721 | $267.3K | 0.00% | +1,089+7.4% | Added |
| Scientech Research LLC | 15,573 | $264.7K | 0.17% | +15,573 | New |
| Winton Group Ltd | 14,700 | $249.9K | 0.01% | +14,700 | New |
| Profund Advisors LLC | 14,585 | $247.9K | 0.01% | −10,137−41.0% | Reduced |
| Savant Capital, LLC | 12,951 | $220.2K | 0.00% | +12,951 | New |
| First Trust Advisors LP | 11,688 | $198.7K | 0.00% | +11,688 | New |
| Rafferty Asset Management, LLC | 11,557 | $196.5K | 0.00% | −5,064−30.5% | Reduced |
| Palumbo Wealth Management LLC | 11,356 | $193.1K | 0.05% | +11,356 | New |
| Public Employees Retirement System of Ohio | 10,700 | $181.9K | 0.00% | +10,700 | New |
| Inceptionr LLC | 10,636 | $180.8K | 0.05% | −24,007−69.3% | Reduced |
| Caitong International Asset Management Co., Ltd | 10,357 | $176.1K | 0.04% | +10,357 | New |
| Bessemer Group Inc | 9,962 | $170.0K | 0.00% | +37+0.4% | Added |
| Tower Research Capital LLC (TRC) | 9,529 | $162.0K | 0.00% | +6,332+198.1% | Added |
| Ameritas Investment Partners, Inc. | 9,364 | $159.2K | 0.00% | 00.0% | Unchanged |
| Mirae Asset Global Investments Co., Ltd. | 8,124 | $138.1K | 0.00% | +1,972+32.1% | Added |
| US Bancorp | 6,263 | $106.5K | 0.00% | −1,425−18.5% | Reduced |
| Acadian Asset Management LLC | 5,823 | $98.0K | 0.00% | +5,823 | New |
| Amalgamated Bank | 3,637 | $62.0K | 0.00% | +309+9.3% | Added |
| GF Fund Management Co. Ltd. | 3,285 | $55.8K | 0.00% | −139−4.1% | Reduced |
| Ancora Advisors, LLC | 3,000 | $51.0K | 0.00% | 00.0% | Unchanged |
| Quadrant Capital Group LLC | 2,396 | $40.7K | 0.00% | 00.0% | Unchanged |
| Smartleaf Asset Management LLC | 2,243 | $38.5K | 0.00% | +1,942+645.2% | Added |
| CWM, LLC | 2,117 | $36.0K | 0.00% | +2,086+6,729.0% | Added |
| Farther Finance Advisors, LLC | 1,945 | $33.1K | 0.00% | +375+23.9% | Added |
| Sterling Capital Management LLC | 1,424 | $24.2K | 0.00% | +298+26.5% | Added |
| Nisa Investment Advisors, LLC | 1,308 | $22.2K | 0.00% | −268−17.0% | Reduced |
| Advisor Group Holdings, Inc. | 1,175 | $20.0K | 0.00% | +194+19.8% | Added |
| Rockefeller Capital Management L.P. | 861 | $14.6K | 0.00% | +861 | New |
| Larson Financial Group LLC | 842 | $14.3K | 0.00% | +150+21.7% | Added |
| GAMMA Investing LLC | 692 | $11.8K | 0.00% | +251+56.9% | Added |
| Bryn Mawr Trust Co | 580 | $9.86K | 0.00% | +580 | New |
| Daiwa Securities Group Inc. | 503 | $9.00K | 0.00% | 00.0% | Unchanged |
| Jones Financial Companies LLLP | 500 | $8.50K | 0.00% | +500 | New |
| Global Retirement Partners, LLC | 500 | $8.50K | 0.00% | +500 | New |
| Massmutual Trust Co FSB | 429 | $7.29K | 0.00% | −299−41.1% | Reduced |
| Steward Partners Investment Advisory, LLC | 400 | $6.80K | 0.00% | 00.0% | Unchanged |
| Entrust Financial LLC | 345 | $5.87K | 0.00% | +345 | New |
| Signaturefd, LLC | 310 | $5.27K | 0.00% | 00.0% | Unchanged |
| Cygnus Capital Advisors, LLC | 271 | $5.00K | 0.00% | +271 | New |
| Rothschild Investment LLC | 292 | $4.96K | 0.00% | +47+19.2% | Added |
| J.Safra Asset Management Corp | 262 | $4.45K | 0.00% | +262 | New |
| Optiver Holding B.V. | 258 | $4.39K | 0.00% | −742−74.2% | Reduced |
| Aster Capital Management (DIFC) Ltd | 248 | $4.22K | 0.00% | +248 | New |
| Basecamp Wealth Advisors LLC | 234 | $3.98K | 0.00% | +234 | New |