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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

Q4 2025 vs. Q3 2025

How the institutions holding Wave Life Sciences, Inc. changed between Q3 2025 and Q4 2025.

All holders in Q4 2025All holders in Q3 2025

13F holders of WVE: Q3 2025 compared with Q4 2025
MeasureQ3 2025Of which not filed for Q4 2025Q4 2025Change
Holders1895219+35
Shares143.7M73.6K182.7M+39.1M (+27.3%)
Value$1.05B$536.4K$3.11B+$2.06B (+195.7%)

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so the changes leave them out.

New holders (73)

Institutions that held Wave Life Sciences, Inc. at the end of Q4 2025 but not at the end of Q3 2025.

Institutions new to WVE in Q4 2025
InstitutionSharesValue% of portfolio
GSK plc18,245,691$310.2M38.82%
Darwin Global Management, Ltd.7,298,421$125.2M2.53%
First Light Asset Management, LLC1,853,851$31.5M2.41%
Citadel Advisors LLC789,964$13.4M0.01%
Voloridge Investment Management, LLC722,237$12.3M0.04%
Tang Capital Management LLC600,000$10.2M0.50%
Eventide Asset Management, LLC500,000$8.50M0.13%
Elmind Capital, LP447,846$7.61M2.25%
Exome Asset Management LLC421,488$7.17M3.54%
Trexquant Investment LP391,111$6.65M0.06%
Boone Capital Management LLC352,144$5.99M1.88%
Woodline Partners LP350,531$5.96M0.02%
Jacobs Levy Equity Management, Inc338,546$5.76M0.02%
Jain Global LLC328,145$5.58M0.05%
Jump Financial, LLC313,509$5.33M0.07%
HRT Financial LP299,718$5.09M0.02%
D. E. Shaw & Co., Inc.266,132$4.52M0.00%
EAM Investors, LLC248,815$4.23M0.47%
Renaissance Technologies LLC236,420$4.02M0.01%
Nomura Asset Management International Inc.203,744$3.46M0.01%
Squadron Capital Management LLC175,000$2.98M1.33%
Duquesne Family Office LLCSuperinvestorDuquesne Family Office173,000$2.94M0.07%
Principal Financial Group Inc170,170$2.89M0.00%
UBS Asset Management Americas Inc164,985$2.80M0.00%
Burkehill Global Management, LP150,000$2.55M0.17%
Algert Global LLC122,470$2.08M0.03%
Itau Unibanco Holding S.A.102,000$1.75M0.04%
LMR Partners LLP100,000$1.70M0.02%
Seven Grand Managers, LLC100,000$1.70M0.13%
Prelude Capital Management, LLC93,202$1.58M0.12%
Prescott Group Capital Management, L.L.C.90,000$1.53M0.14%
Connor, Clark & Lunn Investment Management Ltd.69,078$1.17M0.00%
SG Americas Securities, LLC67,031$1.14M0.00%
J. Goldman & Co LP53,762$914.0K0.04%
Glenmede Trust Co NA42,732$726.4K0.00%
Gainplan LLC39,972$679.5K0.26%
State of New Jersey Common Pension Fund D38,022$646.4K0.00%
PSP Research LLC31,040$527.7K0.46%
Entropy Technologies, LP30,613$520.4K0.03%
Vestmark Advisory Solutions, Inc.30,421$517.2K0.01%
AlphaCentric Advisors LLC27,590$469.0K0.47%
Virtu Financial LLC26,889$457.0K0.02%
Exchange Traded Concepts, LLC25,615$435.5K0.00%
Allianz Asset Management GmbH22,000$374.0K0.00%
Advisory Services Network, LLC20,900$355.3K0.01%
Persistent Asset Partners Ltd19,827$337.1K0.16%
FORA Capital, LLC19,194$326.3K0.04%
Scientech Research LLC15,573$264.7K0.17%
Winton Group Ltd14,700$249.9K0.01%
Savant Capital, LLC12,951$220.2K0.00%
First Trust Advisors LP11,688$198.7K0.00%
Palumbo Wealth Management LLC11,356$193.1K0.05%
Public Employees Retirement System of Ohio10,700$181.9K0.00%
Caitong International Asset Management Co., Ltd10,357$176.1K0.04%
Acadian Asset Management LLC5,823$98.0K0.00%
Rockefeller Capital Management L.P.861$14.6K0.00%
Bryn Mawr Trust Co580$9.86K0.00%
Jones Financial Companies LLLP500$8.50K0.00%
Global Retirement Partners, LLC500$8.50K0.00%
Entrust Financial LLC345$5.87K0.00%
Cygnus Capital Advisors, LLC271$5.00K0.00%
J.Safra Asset Management Corp262$4.45K0.00%
Aster Capital Management (DIFC) Ltd248$4.22K0.00%
Basecamp Wealth Advisors LLC234$3.98K0.00%
Fourth Dimension Wealth, LLC150$2.55K0.00%
CVA Family Office, LLC128$2.18K0.00%
Cornerstone Financial Management LLC86$1.46K0.00%
Essential Partners LLC36$6120.00%
SJS Investment Consulting Inc.17$2890.00%
SRS Capital Advisors, Inc.14$2380.00%
MAI Capital Management11$1870.00%
IFP Advisors, Inc9$1530.00%
Hughes Financial Services, LLC1$170.00%

Sold out (38)

Institutions that held Wave Life Sciences, Inc. at the end of Q3 2025 and filed for Q4 2025 without it.

Institutions that sold out of WVE in Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
StemPoint Capital LP2,110,152$15.4M
MPM Oncology Impact Management LP1,505,262$11.0M
Artisan Partners Limited Partnership1,232,926$9.03M
Polar Capital Holdings Plc1,062,276$7.78M
Point72 Asset Management, L.P.663,967$4.86M
Ensign Peak Advisors, Inc313,307$2.29M
Avidity Partners Management LP297,500$2.18M
Two Sigma Advisers, LP251,700$1.84M
Qube Research & Technologies Ltd127,983$936.8K
ADAR1 Capital Management, LLC119,067$871.6K
ExodusPoint Capital Management, LP94,080$688.7K
Macquarie Group Ltd81,955$600.0K
Twinbeech Capital LP65,091$476.5K
Franklin Resources Inc62,259$455.7K
HighVista Strategies LLC59,261$433.8K
SummitTX Capital, L.P.53,611$392.4K
Gsa Capital Partners LLP51,198$375.0K
Graham Capital Management, L.P.43,946$321.7K
Fox Run Management, L.L.C.41,988$307.4K
Omers Administration Corp40,000$292.8K
Engineers Gate Manager LP27,489$201.2K
Balyasny Asset Management LLC18,427$134.9K
Martingale Asset Management L P16,252$119.0K
Velan Capital Investment Management LP15,000$109.8K
Marshall Wace, LLP14,000$102.5K
Kraematon Investment Advisors, Inc13,450$98.5K
Prudential Financial Inc12,375$90.6K
Caption Management, LLC12,000$87.8K
Verdence Capital Advisors LLC11,307$86.2K
NJ State Employees Deferred Compensation Plan11,700$85.6K
Chicago Partners Investment Group LLC10,572$80.2K
Capstone Investment Advisors, LLC10,406$76.2K
Federation des caisses Desjardins du Quebec2,350$17.2K
Wealthspire Advisors, LLC1,350$9.88K
Versant Capital Management, Inc108$791
Montag A & Associates Inc59$432
Principal Securities, Inc.58$425
American National Bank50$366

Not filed for Q4 2025 yet (5)

Institutions that held Wave Life Sciences, Inc. at the end of Q3 2025 and haven't filed a 13F for Q4 2025. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding WVE in Q3 2025 that haven't filed for Q4 2025
InstitutionShares, Q3 2025Value, Q3 2025
Glenmede Investment Management, LP44,326$324.5K
CIBC Bancorp USA Inc.11,948$87.5K
Wolverine Trading, LLC11,803$84.2K
Point72 Hong Kong Ltd4,753$34.8K
Point72 (DIFC) Ltd752$5.51K