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Wave Life Sciences, Inc.

WVE
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001631574

In the last 90 days, Wave Life Sciences, Inc. insiders filed 0 open-market purchases and 4 sales; 239 institutions reported holding it in 13F filings for Q2 2026, worth $1.06B in total; superinvestors Maverick Capital and Duquesne Family Office hold it.

13F holders, Q4 2025

Institutional positions in Wave Life Sciences, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
219
+35 vs. Q3 2025
Shares held
182.7M
+39.1M (+27.3%) vs. Q3 2025
Total value
$3.11B
+$2.06B (+195.7%) vs. Q3 2025
New holders
73
79 more added
Sold out
38
47 more reduced

5 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting WVE on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2025: 219 institutions
Q1 2021: 102 institutionsQ2 2021: 87 institutionsQ3 2021: 88 institutionsQ4 2021: 90 institutionsQ1 2022: 82 institutionsQ2 2022: 60 institutionsQ3 2022: 61 institutionsQ4 2022: 75 institutionsQ1 2023: 73 institutionsQ2 2023: 81 institutionsQ3 2023: 85 institutionsQ4 2023: 115 institutionsQ1 2024: 132 institutionsQ2 2024: 144 institutionsQ3 2024: 162 institutionsQ4 2024: 184 institutionsQ1 2025: 197 institutionsQ2 2025: 177 institutionsQ3 2025: 189 institutionsQ4 2025: 219 institutionsQ1 2026: 232 institutionsQ2 2026: 239 institutions
Value heldQ4 2025: $3.11B
Q1 2021: $214.8MQ2 2021: $246.7MQ3 2021: $183.5MQ4 2021: $148.5MQ1 2022: $95.4MQ2 2022: $220.3MQ3 2022: $242.8MQ4 2022: $476.9MQ1 2023: $303.5MQ2 2023: $262.7MQ3 2023: $417.4MQ4 2023: $468.0MQ1 2024: $572.3MQ2 2024: $474.4MQ3 2024: $986.1MQ4 2024: $1.59BQ1 2025: $1.06BQ2 2025: $903.1MQ3 2025: $1.05BQ4 2025: $3.11BQ1 2026: $1.25BQ2 2026: $1.06B
Institutions holding WVE and their total value by quarter
QuarterHoldersValue
Q2 2026239$1.06B
Q1 2026232$1.25B
Q4 2025219$3.11B
Q3 2025189$1.05B
Q2 2025177$903.1M
Q1 2025197$1.06B
Q4 2024184$1.59B
Q3 2024162$986.1M
Q2 2024144$474.4M
Q1 2024132$572.3M
Q4 2023115$468.0M
Q3 202385$417.4M
Q2 202381$262.7M
Q1 202373$303.5M
Q4 202275$476.9M
Q3 202261$242.8M
Q2 202260$220.3M
Q1 202282$95.4M
Q4 202190$148.5M
Q3 202188$183.5M
Q2 202187$246.7M
Q1 2021102$214.8M

Institutions, Q4 2025

Shares, value and share of portfolio for each institution holding Wave Life Sciences, Inc.; share changes are against Q3 2025.

Institutions holding WVE in Q4 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Covestor Ltd13$00.00%00.0%Unchanged
Hughes Financial Services, LLC1$170.00%+1New
IFP Advisors, Inc9$1530.00%+9New
The PNC Financial Services Group, Inc.10$1700.00%−313−96.9%Reduced
MAI Capital Management11$1870.00%+11New
SRS Capital Advisors, Inc.14$2380.00%+14New
SJS Investment Consulting Inc.17$2890.00%+17New
Essential Partners LLC36$6120.00%+36New
True Wealth Design, LLC37$6290.00%00.0%Unchanged
Truvestments Capital LLC57$9660.00%+55+2,750.0%Added
SBI Securities Co., Ltd.60$1.02K0.00%−45−42.9%Reduced
Parkside Financial Bank & Trust72$1.22K0.00%00.0%Unchanged
Cornerstone Financial Management LLC86$1.46K0.00%+86New
Parallel Advisors, LLC95$1.61K0.00%00.0%Unchanged
CVA Family Office, LLC128$2.18K0.00%+128New
Allworth Financial LP129$2.19K0.00%+5+4.0%Added
Fourth Dimension Wealth, LLC150$2.55K0.00%+150New
ORG Partners LLC200$3.40K0.00%+100+100.0%Added
EverSource Wealth Advisors, LLC224$3.81K0.00%+24+12.0%Added
Basecamp Wealth Advisors LLC234$3.98K0.00%+234New
Aster Capital Management (DIFC) Ltd248$4.22K0.00%+248New
Optiver Holding B.V.258$4.39K0.00%−742−74.2%Reduced
J.Safra Asset Management Corp262$4.45K0.00%+262New
Rothschild Investment LLC292$4.96K0.00%+47+19.2%Added
Cygnus Capital Advisors, LLC271$5.00K0.00%+271New
Signaturefd, LLC310$5.27K0.00%00.0%Unchanged
Entrust Financial LLC345$5.87K0.00%+345New
Steward Partners Investment Advisory, LLC400$6.80K0.00%00.0%Unchanged
Massmutual Trust Co FSB429$7.29K0.00%−299−41.1%Reduced
Jones Financial Companies LLLP500$8.50K0.00%+500New
Global Retirement Partners, LLC500$8.50K0.00%+500New
Daiwa Securities Group Inc.503$9.00K0.00%00.0%Unchanged
Bryn Mawr Trust Co580$9.86K0.00%+580New
GAMMA Investing LLC692$11.8K0.00%+251+56.9%Added
Larson Financial Group LLC842$14.3K0.00%+150+21.7%Added
Rockefeller Capital Management L.P.861$14.6K0.00%+861New
Advisor Group Holdings, Inc.1,175$20.0K0.00%+194+19.8%Added
Nisa Investment Advisors, LLC1,308$22.2K0.00%−268−17.0%Reduced
Sterling Capital Management LLC1,424$24.2K0.00%+298+26.5%Added
Farther Finance Advisors, LLC1,945$33.1K0.00%+375+23.9%Added
CWM, LLC2,117$36.0K0.00%+2,086+6,729.0%Added
Smartleaf Asset Management LLC2,243$38.5K0.00%+1,942+645.2%Added
Quadrant Capital Group LLC2,396$40.7K0.00%00.0%Unchanged
Ancora Advisors, LLC3,000$51.0K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.3,285$55.8K0.00%−139−4.1%Reduced
Amalgamated Bank3,637$62.0K0.00%+309+9.3%Added
Acadian Asset Management LLC5,823$98.0K0.00%+5,823New
US Bancorp6,263$106.5K0.00%−1,425−18.5%Reduced
Mirae Asset Global Investments Co., Ltd.8,124$138.1K0.00%+1,972+32.1%Added
Ameritas Investment Partners, Inc.9,364$159.2K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)9,529$162.0K0.00%+6,332+198.1%Added
Bessemer Group Inc9,962$170.0K0.00%+37+0.4%Added
Caitong International Asset Management Co., Ltd10,357$176.1K0.04%+10,357New
Inceptionr LLC10,636$180.8K0.05%−24,007−69.3%Reduced
Public Employees Retirement System of Ohio10,700$181.9K0.00%+10,700New
Palumbo Wealth Management LLC11,356$193.1K0.05%+11,356New
Rafferty Asset Management, LLC11,557$196.5K0.00%−5,064−30.5%Reduced
First Trust Advisors LP11,688$198.7K0.00%+11,688New
Savant Capital, LLC12,951$220.2K0.00%+12,951New
Profund Advisors LLC14,585$247.9K0.01%−10,137−41.0%Reduced
Winton Group Ltd14,700$249.9K0.01%+14,700New
Scientech Research LLC15,573$264.7K0.17%+15,573New
Victory Capital Management Inc15,721$267.3K0.00%+1,089+7.4%Added
Virtus Investment Advisers, Inc.16,064$273.1K0.07%+260+1.6%Added
Teacher Retirement System of Texas16,443$279.5K0.00%−10,155−38.2%Reduced
State Board of Administration of Florida Retirement System16,950$288.1K0.00%00.0%Unchanged
HSBC Holdings PLC16,990$290.9K0.00%+5,823+52.1%Added
Cresset Asset Management, LLC17,929$304.8K0.00%+2,905+19.3%Added
Creative Planning18,121$308.1K0.00%+6,251+52.7%Added
FORA Capital, LLC19,194$326.3K0.04%+19,194New
Persistent Asset Partners Ltd19,827$337.1K0.16%+19,827New
Advisory Services Network, LLC20,900$355.3K0.01%+20,900New
Simplex Trading, LLC21,126$359.1K0.01%+19,920+1,651.7%Added
Allianz Asset Management GmbH22,000$374.0K0.00%+22,000New
HighTower Advisors, LLC22,830$388.1K0.00%+10,666+87.7%Added
Royal Bank of Canada23,206$396.0K0.00%−147,292−86.4%Reduced
KLP Kapitalforvaltning AS24,000$408.0K0.00%+3,200+15.4%Added
Brinker Capital Investments, LLC25,030$425.5K0.00%−385−1.5%Reduced
Exchange Traded Concepts, LLC25,615$435.5K0.00%+25,615New
Virtu Financial LLC26,889$457.0K0.02%+26,889New
AlphaCentric Advisors LLC27,590$469.0K0.47%+27,590New
ProShare Advisors LLC28,536$485.1K0.00%+3,701+14.9%Added
Vestmark Advisory Solutions, Inc.30,421$517.2K0.01%+30,421New
Entropy Technologies, LP30,613$520.4K0.03%+30,613New
Arizona State Retirement System30,645$521.0K0.00%−1,545−4.8%Reduced
Intech Investment Management LLC30,667$521.3K0.00%−15,221−33.2%Reduced
Police & Firemen's Retirement System of New Jersey31,033$527.6K0.00%00.0%Unchanged
PSP Research LLC31,040$527.7K0.46%+31,040New
Man Group plc31,418$534.1K0.00%−101,353−76.3%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.33,839$539.7K0.00%−2,330−6.4%Reduced
Walleye Trading LLC33,241$565.1K0.01%+32,176+3,021.2%Added
New York State Common Retirement Fund35,920$610.6K0.00%−71,126−66.4%Reduced
State of New Jersey Common Pension Fund D38,022$646.4K0.00%+38,022New
Quantinno Capital Management LP38,925$661.7K0.00%−6,124−13.6%Reduced
China Universal Asset Management Co., Ltd.39,742$675.6K0.05%−38,153−49.0%Reduced
Envestnet Asset Management Inc39,820$676.9K0.00%−27−0.1%Reduced
Gainplan LLC39,972$679.5K0.26%+39,972New
Matisse Capital42,193$717.3K0.32%+29,000+219.8%Added
Glenmede Trust Co NA42,732$726.4K0.00%+42,732New
Citigroup Inc46,759$794.9K0.00%+12,246+35.5%Added