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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Motco19$9.44K0.00%+5+35.7%Added
Hughes Financial Services, LLC19$9.44K0.00%+9+90.0%Added
J.Safra Asset Management Corp20$9.94K0.00%00.0%Unchanged
Penserra Capital Management LLC21$10.0K0.00%00.0%Unchanged
Caldwell Sutter Capital, Inc.21$10.4K0.00%00.0%Unchanged
Osterweis Capital Management Inc21$10.4K0.00%00.0%Unchanged
Aspect Partners, LLC21$10.4K0.00%00.0%Unchanged
Cetera Trust Company, N.A21$10.4K0.01%00.0%Unchanged
Colonial Trust Co21$10.7K0.00%00.0%Unchanged
Westfuller Advisors, LLC22$10.7K0.00%00.0%Unchanged
Dynamic Wealth Strategies, LLC22$10.9K0.01%00.0%Unchanged
WestEnd Advisors, LLC22$10.9K0.00%+3+15.8%Added
LFA - Lugano Financial Advisors SA23$11.4K0.01%00.0%Unchanged
Altshuler Shaham Ltd24$11.9K0.00%+15+166.7%Added
Tompkins Financial Corp24$11.9K0.00%+24New
Dunhill Financial, LLC24$11.9K0.00%−1−4.0%Reduced
Tidemark, LLC25$12.4K0.00%−1−3.8%Reduced
Tanglewood Legacy Advisors, LLC25$12.4K0.00%00.0%Unchanged
Main Street Group, LTD25$12.4K0.00%00.0%Unchanged
Ameriflex Group, Inc.26$12.9K0.01%−161−86.1%Reduced
Chilton Capital Management LLC26$12.9K0.00%−32−55.2%Reduced
Hoey Investments, Inc26$12.9K0.00%+3+13.0%Added
DiNuzzo Private Wealth, Inc.27$13.4K0.00%00.0%Unchanged
Virginia Estate & Retirement Planning Advisors Inc.27$13.4K0.02%00.0%Unchanged
Bay Harbor Wealth Management, LLC27$13.4K0.00%+9+50.0%Added
Rakuten Securities, Inc.28$13.9K0.00%+8+40.0%Added
Proffitt & Goodson Inc28$13.9K0.00%00.0%Unchanged
Strategic Wealth Advisors LLC32$14.0K0.01%00.0%Unchanged
Principia Wealth Advisory, LLC29$14.4K0.01%+13+81.3%Added
Frazier Financial Advisors, LLC29$14.4K0.01%00.0%Unchanged
FWL Investment Management, LLC30$14.9K0.00%00.0%Unchanged
Caitlin John, LLC31$15.4K0.01%00.0%Unchanged
Orion Capital Management LLC32$15.9K0.00%00.0%Unchanged
Lummis Asset Management, LP32$15.9K0.01%+3+10.3%Added
Beaird Harris Wealth Management, LLC33$16.4K0.00%00.0%Unchanged
Valued Wealth Advisors LLC35$17.2K0.01%−2−5.4%Reduced
Indiana Trust & Investment Management CO35$17.4K0.00%00.0%Unchanged
Greykasell Wealth Strategies, Inc.38$18.9K0.01%−9−19.1%Reduced
Heritage Wealth Advisors38$18.9K0.00%00.0%Unchanged
Trust Co38$18.9K0.00%00.0%Unchanged
Creative Capital Management Investments LLC40$19.9K0.00%+16+66.7%Added
Private Wealth Management Group, LLC40$19.9K0.00%00.0%Unchanged
DT Investment Partners, LLC44$21.9K0.00%00.0%Unchanged
South State Corp.45$22.4K0.00%−2−4.3%Reduced
Burk Holdings LLC45$22.4K0.01%00.0%Unchanged
Marquette Asset Management, LLC45$22.4K0.00%+3+7.1%Added
IMG Wealth Management, Inc.45$22.4K0.01%+8+21.6%Added
Planning Strategies Inc.45$22.4K0.01%+45New
Archer Investment Corp46$22.9K0.00%+7+17.9%Added
LifeSteps Financial, Inc.47$23.3K0.01%+47New
Evelyn Partners Group Ltd47$23.3K0.00%+47New
Tounjian Advisory Partners, LLC49$24.3K0.01%+49New
Dogwood Wealth Management LLC50$24.8K0.01%−22−30.6%Reduced
Hilton Head Capital Partners, LLC50$24.8K0.01%00.0%Unchanged
Wilkerson Advisory Group LLC50$24.8K0.01%+2+4.2%Added
Toews Corp50$24.8K0.00%+50New
Bullock Wealth Management Group50$24.9K0.01%00.0%Unchanged
Abound Wealth Management50$25.0K0.00%−26−34.2%Reduced
Signature Equity Partners, LLC51$25.3K0.01%−296−85.3%Reduced
Meeder Asset Management Inc52$25.8K0.00%−3,372−98.5%Reduced
Avion Wealth53$26.0K0.00%+14+35.9%Added
Chesapeake Asset Management LLC53$26.3K0.02%−10−15.9%Reduced
Community Financial Services Group, LLC53$26.4K0.00%+53New
Pinnacle Bancorp, Inc.54$26.8K0.01%00.0%Unchanged
Cedar Mountain Advisors, LLC54$26.8K0.00%00.0%Unchanged
Aventura Private Wealth, LLC54$26.8K0.01%00.0%Unchanged
ZRC Wealth Management, LLC55$27.3K0.01%+28+103.7%Added
Wedbush Fund Advisers, LLC57$28.3K0.00%00.0%Unchanged
Activest Wealth Management58$28.8K0.01%+12+26.1%Added
Strategic Investment Solutions, Inc.58$28.8K0.01%00.0%Unchanged
SJS Investment Consulting Inc.59$29.3K0.00%+28+90.3%Added
Atlas Capital Advisors LLC60$29.8K0.00%−50−45.5%Reduced
Access Investment Management LLC60$29.8K0.01%00.0%Unchanged
BFSG, LLC61$30.3K0.00%00.0%Unchanged
Canton Hathaway, LLC62$30.8K0.01%00.0%Unchanged
Thurston, Springer, Miller, Herd & Titak, Inc.63$31.3K0.01%00.0%Unchanged
Pingora Partners LLC65$32.3K0.02%00.0%Unchanged
North Star Investment Management Corp.65$32.3K0.00%+3+4.8%Added
Prosperity Bancshares Inc65$32.3K0.02%+4+6.6%Added
Raffa Wealth Management, LLC66$32.8K0.00%+4+6.5%Added
ORG Wealth Partners, LLC68$33.8K0.01%+42+161.5%Added
Estabrook Capital Management69$34.3K0.00%00.0%Unchanged
Fortitude Family Office, LLC72$35.8K0.01%−3−4.0%Reduced
Horizon Financial Services, LLC72$35.8K0.01%+29+67.4%Added
Anchor Bay Capital, Inc.69$36.1K0.02%+69New
City Holding Co73$36.3K0.00%+41+128.1%Added
Alphadyne Asset Management LP73$36.3K0.00%−8,849−99.2%Reduced
Ogorek Anthony Joseph78$38.0K0.01%00.0%Unchanged
1248 Management, LLC78$38.7K0.02%−1,265−94.2%Reduced
Stone House Investment Management, LLC78$38.7K0.01%−5−6.0%Reduced
SOA Wealth Advisors, LLC.78$38.7K0.01%00.0%Unchanged
Evolution Wealth Management Inc.78$38.7K0.02%+26+50.0%Added
Financial Management Professionals, Inc.80$39.7K0.00%00.0%Unchanged
Action Point Financial Planning, LLC84$39.8K0.00%+84New
Catalyst Capital Advisors LLC82$40.7K0.00%−25−23.4%Reduced
TD Capital Management LLC82$40.7K0.00%00.0%Unchanged
Centerpoint Advisors, LLC87$43.0K0.01%00.0%Unchanged
Wolff Wiese Magana LLC89$44.2K0.02%00.0%Unchanged
Rational Advisors LLC92$45.7K0.00%+8+9.5%Added
Perkins Coie Trust Co95$47.2K0.01%+95New