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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2026

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,763
+84 vs. Q1 2026
Shares held
241.5M
+5.89M (+2.5%) vs. Q1 2026
Total value
$119.7B
+$14.6B (+13.9%) vs. Q1 2026
New holders
194
707 more added
Sold out
110
623 more reduced

19 institutions that held it in Q1 2026 haven't filed for Q2 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 1,763 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2026: $119.7B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2026.

Institutions holding VRTX in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Guggenheim Capital LLC115,233$57.2M0.37%+14,847+14.8%Added
Credit Agricole S A115,955$57.6M0.15%−6,410−5.2%Reduced
Nomura Asset Management Co Ltd120,235$59.7M0.13%−932−0.8%Reduced
Bowen Hanes & Co Inc135,399$60.5M1.47%00.0%Unchanged
ABN AMRO Bank N.V.125,970$62.5M0.81%+7,621+6.4%Added
Creative Planning127,672$63.4M0.04%+18,148+16.6%Added
KBC Group NV128,466$63.8M0.14%+1,258+1.0%Added
Colony Group, LLC128,958$64.1M0.07%−2,477−1.9%Reduced
SEI Investments Co129,981$64.6M0.06%−3,245−2.4%Reduced
Vanguard Investments Australia, Ltd.130,109$64.6M0.16%+3,848+3.0%Added
Los Angeles Capital Management LLC130,802$65.0M0.24%+65,865+101.4%Added
Prudential Financial Inc133,294$66.2M0.07%+1,734+1.3%Added
Mariner, LLC134,614$66.9M0.07%+3,014+2.3%Added
Connor, Clark & Lunn Investment Management Ltd.135,236$67.2M0.13%−116,475−46.3%Reduced
Teacher Retirement System of Texas135,619$67.4M0.18%+11,302+9.1%Added
State of Wisconsin Investment Board135,798$67.5M0.14%−750−0.5%Reduced
SEB Asset Management AB138,097$68.6M0.26%−2,854−2.0%Reduced
Man Group plc139,233$69.2M0.13%−97,565−41.2%Reduced
Asset Management One Co.,Ltd.139,597$69.3M0.18%−2,352−1.7%Reduced
Woodline Partners LP140,288$69.7M0.22%+5,334+4.0%Added
Provident Investment Management, Inc.140,728$69.9M6.79%−6,892−4.7%Reduced
Allspring Global Investments Holdings, LLC140,631$70.0M0.11%+16,871+13.6%Added
Van Eck Associates Corp143,881$71.5M0.04%−2,235−1.5%Reduced
Susquehanna International Group, LLP144,174$71.6M0.06%+123,953+613.0%Added
Balyasny Asset Management LLC145,005$72.0M0.13%+104,868+261.3%Added
Birch Hill Investment Advisors LLC147,702$73.4M2.97%−3,093−2.1%Reduced
Harvest Portfolios Group Inc.148,195$73.6M1.04%+148,195New
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund148,682$73.9M0.35%−1,280−0.9%Reduced
Rockefeller Capital Management L.P.149,476$74.2M0.11%−179−0.1%Reduced
Mirae Asset Global ETFs Holdings Ltd.150,692$74.7M0.09%−21,233−12.4%Reduced
Danske Bank A/S158,064$78.5M0.16%+5,058+3.3%Added
Nomura Asset Management International Inc.159,549$79.3M0.12%+3,065+2.0%Added
Stifel Financial Corp162,151$80.5M0.07%+1,099+0.7%Added
Carmignac Gestion163,045$81.0M1.05%+14,846+10.0%Added
Quantinno Capital Management LP163,085$81.0M0.10%+36,481+28.8%Added
Capital International Inc164,407$81.7M0.57%+2,684+1.7%Added
Lord, Abbett & Co. LLC166,581$82.7M0.24%+720.0%Added
CIBC Bancorp USA Inc.166,673$82.8M0.10%+102,721+160.6%Added
Schroder Investment Management Group169,270$84.6M0.06%+5,372+3.3%Added
National Bank of Canada172,898$85.9M0.08%−99,219−36.5%Reduced
Mitsubishi UFJ Trust & Banking Corp174,812$86.8M0.19%+7,909+4.7%Added
Healthcare of Ontario Pension Plan Trust Fund177,679$88.3M0.13%+69,428+64.1%Added
Great West Life Assurance Co182,365$90.4M0.14%−9,779−5.1%Reduced
Groupama Asset Managment188,156$93.9M1.18%+22,259+13.4%Added
NEOS Investment Management LLC193,306$96.0M0.35%+19,219+11.0%Added
Candriam Luxembourg S.C.A.199,505$99.0M0.45%−29,410−12.8%Reduced
Tri Locum Partners LP201,791$100.2M12.33%+72,477+56.0%Added
Nykredit A/S204,386$101.5M0.39%+204,386New
APG Asset Management N.V.234,624$101.9M0.25%+43,239+22.6%Added
New York State Teachers Retirement System206,935$102.8M0.19%−4,401−2.1%Reduced
Davenport & Co LLC207,108$103.0M0.53%−3,044−1.4%Reduced
TD Asset Management Inc207,960$103.3M0.09%−20,235−8.9%Reduced
Agf Management Ltd207,971$103.3M0.40%+6,568+3.3%Added
Mirae Asset Global Investments Co., Ltd.210,209$104.4M0.20%+22,145+11.8%Added
Ensign Peak Advisors, Inc210,483$104.6M0.17%−4,682−2.2%Reduced
Standard Life Aberdeen plc210,601$104.6M0.15%−22,879−9.8%Reduced
Capital International Sarl210,718$104.7M1.48%+1,836+0.9%Added
Jones Financial Companies LLLP215,419$105.8M0.04%+12,559+6.2%Added
Korea Investment CORP213,312$106.0M0.20%+12,144+6.0%Added
Handelsbanken Fonder AB218,292$108.4M0.31%−2,555−1.2%Reduced
State Board of Administration of Florida Retirement System219,813$109.2M0.18%−4,842−2.2%Reduced
Welch & Forbes LLC221,304$109.9M1.34%+1,635+0.7%Added
ING Groep NV223,124$110.8M0.54%+157,699+241.0%Added
Aviva PLC223,593$111.1M0.16%+1,141+0.5%Added
B. Metzler seel. Sohn & Co. AG231,381$114.9M0.99%−279,655−54.7%Reduced
Royal London Asset Management Ltd241,280$119.9M0.22%−10,912−4.3%Reduced
Public Employees Retirement Association of Colorado250,189$124.3M0.43%−61,561−19.7%Reduced
Cerity Partners LLC255,874$127.1M0.15%−40,780−13.7%Reduced
BNP Paribas Arbitrage, SA262,258$130.3M0.07%−153,367−36.9%Reduced
Baillie Gifford & Co272,561$135.4M0.12%+73,140+36.7%Added
New York State Common Retirement Fund277,614$137.9M0.17%−14,800−5.1%Reduced
Swedbank AB282,444$140.3M0.12%+10,891+4.0%Added
Two Sigma Investments, LP285,000$141.6M0.11%−93,146−24.6%Reduced
ProShare Advisors LLC287,847$143.0M0.21%−85,685−22.9%Reduced
LPL Financial LLC289,111$143.6M0.03%+21,049+7.9%Added
First Trust Advisors LP289,179$143.6M0.08%−17,282−5.6%Reduced
AMF Pensionsforsakring AB314,765$156.4M0.93%+1,848+0.6%Added
Bank Julius Baer & Co. Ltd, Zurich319,371$158.9M0.41%+1,965+0.6%Added
Renaissance Technologies LLC320,008$159.0M0.22%−101,680−24.1%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH323,752$160.7M0.25%−14,595−4.3%Reduced
Russell Investments Group, Ltd.336,990$167.5M0.15%−30,701−8.3%Reduced
Canada Pension Plan Investment Board355,082$176.4M0.10%+165,031+86.8%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main359,332$178.5M0.14%−5,181−1.4%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)380,762$189.1M0.36%+3,749+1.0%Added
California State Teachers Retirement System383,491$190.5M0.18%+10,010+2.7%Added
Principal Financial Group Inc389,511$193.5M0.10%−37,012−8.7%Reduced
Hudson Bay Capital Management LP390,440$193.9M0.91%+345,440+767.6%Added
Adage Capital Partners GP, L.L.C.393,964$195.7M0.27%+141,974+56.3%Added
Rhumbline Advisers396,380$196.9M0.15%−26,760−6.3%Reduced
Robeco Institutional Asset Management B.V.404,396$200.9M0.25%+2,752+0.7%Added
Chevy Chase Trust Holdings, Inc.406,303$201.8M0.52%−1,312−0.3%Reduced
Bank of Montreal427,448$212.3M0.08%+36,972+9.5%Added
Massachusetts Financial Services Co423,049$214.6M0.07%+95,551+29.2%Added
California Public Employees Retirement System447,499$222.3M0.13%−55,875−11.1%Reduced
Natixis Advisors, L.P.448,631$222.8M0.25%−105,393−19.0%Reduced
DekaBank Deutsche Girozentrale506,457$225.3M0.38%00.0%Unchanged
Millennium Management LLC468,410$232.7M0.16%+437,587+1,419.7%Added
Envestnet Asset Management Inc487,627$242.2M0.06%−15,937−3.2%Reduced
Vanguard Asset Management, Ltd494,186$245.5M0.17%+52,009+11.8%Added
Voya Investment Management LLC505,219$250.4M0.22%−21,828−4.1%Reduced