Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q1 2026
Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,698
- +51 vs. Q4 2025
- Shares held
- 237.8M
- +23.8M (+11.1%) vs. Q4 2025
- Total value
- $106.1B
- +$9.16B (+9.4%) vs. Q4 2025
- New holders
- 155
- 683 more added
- Sold out
- 104
- 600 more reduced
24 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q1 2026
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Candriam Luxembourg S.C.A. | 228,915 | $102.2M | 0.53% | +3,623+1.6% | Added |
| Standard Life Aberdeen plc | 233,480 | $104.3M | 0.17% | −28,577−10.9% | Reduced |
| Man Group plc | 236,798 | $105.7M | 0.22% | −143,937−37.8% | Reduced |
| D. E. Shaw & Co., Inc. | 248,960 | $111.2M | 0.09% | +248,960 | New |
| Connor, Clark & Lunn Investment Management Ltd. | 251,711 | $112.4M | 0.26% | −93,672−27.1% | Reduced |
| Adage Capital Partners GP, L.L.C. | 251,990 | $112.5M | 0.17% | −20,484−7.5% | Reduced |
| Royal London Asset Management Ltd | 252,192 | $112.6M | 0.24% | −21,241−7.8% | Reduced |
| LPL Financial LLC | 268,062 | $119.7M | 0.03% | −8,816−3.2% | Reduced |
| Swedbank AB | 271,553 | $121.3M | 0.13% | +10,810+4.1% | Added |
| National Bank of Canada | 272,117 | $121.5M | 0.12% | +33,569+14.1% | Added |
| New York State Common Retirement Fund | 292,414 | $130.6M | 0.18% | −5,000−1.7% | Reduced |
| Cerity Partners LLC | 296,654 | $132.5M | 0.19% | +35,101+13.4% | Added |
| First Trust Advisors LP | 306,461 | $136.8M | 0.10% | +105,171+52.2% | Added |
| Public Employees Retirement Association of Colorado | 311,750 | $139.2M | 0.55% | −17,995−5.5% | Reduced |
| AMF Pensionsforsakring AB | 312,917 | $139.7M | 0.93% | +166,968+114.4% | Added |
| Harding Loevner LP | 313,546 | $140.0M | 1.44% | −78,319−20.0% | Reduced |
| Bank Julius Baer & Co. Ltd, Zurich | 317,406 | $141.5M | 0.43% | −48,935−13.4% | Reduced |
| Marshall Wace, LLP | 317,058 | $141.6M | 0.15% | +113,026+55.4% | Added |
| Massachusetts Financial Services Co | 327,498 | $149.4M | 0.05% | +115,564+54.5% | Added |
| Pictet Asset Management Holding SA | 337,569 | $150.1M | 0.16% | −414,856−55.1% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 338,347 | $151.0M | 0.26% | +3,449+1.0% | Added |
| Citadel Advisors LLC | 339,298 | $151.5M | 0.11% | −87,762−20.6% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 364,513 | $162.8M | 0.15% | −439,260−54.6% | Reduced |
| Russell Investments Group, Ltd. | 367,691 | $164.0M | 0.18% | −13,771−3.6% | Reduced |
| California State Teachers Retirement System | 373,481 | $166.8M | 0.18% | −12,270−3.2% | Reduced |
| ProShare Advisors LLC | 373,532 | $166.8M | 0.25% | −83,514−18.3% | Reduced |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 377,013 | $168.4M | 0.37% | +23,525+6.7% | Added |
| Two Sigma Investments, LP | 378,146 | $168.9M | 0.14% | +373,991+9,001.0% | Added |
| Bank of Montreal | 390,476 | $174.4M | 0.07% | −37,004−8.7% | Reduced |
| Robeco Institutional Asset Management B.V. | 401,644 | $179.4M | 0.26% | +7,444+1.9% | Added |
| Chevy Chase Trust Holdings, Inc. | 407,615 | $182.0M | 0.52% | −748−0.2% | Reduced |
| BNP Paribas Arbitrage, SA | 415,625 | $185.6M | 0.12% | −143,918−25.7% | Reduced |
| Renaissance Technologies LLC | 421,688 | $188.3M | 0.29% | −83,360−16.5% | Reduced |
| Rhumbline Advisers | 423,140 | $188.9M | 0.16% | −8,122−1.9% | Reduced |
| Principal Financial Group Inc | 426,523 | $190.5M | 0.10% | +11,423+2.8% | Added |
| Life Cycle Investment Partners Ltd | 440,409 | $196.7M | 1.25% | +73,555+20.1% | Added |
| Vanguard Asset Management, Ltd | 442,177 | $197.4M | 0.17% | +442,177 | New |
| Raymond James Financial Inc | 444,496 | $198.5M | 0.06% | +26,365+6.3% | Added |
| California Public Employees Retirement System | 503,374 | $224.8M | 0.14% | −52,690−9.5% | Reduced |
| Envestnet Asset Management Inc | 503,564 | $224.9M | 0.06% | +31,921+6.8% | Added |
| B. Metzler seel. Sohn & Co. AG | 511,036 | $228.2M | 2.12% | −4,233−0.8% | Reduced |
| DekaBank Deutsche Girozentrale | 506,457 | $230.0M | 0.38% | 00.0% | Unchanged |
| Voya Investment Management LLC | 527,047 | $234.9M | 0.24% | −35,305−6.3% | Reduced |
| National Pension Service | 532,069 | $237.6M | 0.18% | +1,228+0.2% | Added |
| Assenagon Asset Management S.A. | 537,248 | $239.9M | 0.38% | −295,605−35.5% | Reduced |
| Franklin Resources Inc | 551,132 | $246.1M | 0.06% | +532+0.1% | Added |
| Neuberger Berman Group LLC | 551,522 | $246.3M | 0.19% | +5,625+1.0% | Added |
| Manufacturers Life Insurance Company, The | 553,243 | $247.0M | 0.21% | −4,470−0.8% | Reduced |
| Natixis Advisors, L.P. | 554,024 | $247.4M | 0.34% | +26,160+5.0% | Added |
| Vanguard Global Advisers, LLC | 555,733 | $248.2M | 0.13% | +555,733 | New |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 597,497 | $266.8M | 0.18% | +31,270+5.5% | Added |
| Sumitomo Mitsui Trust Holdings, Inc. | 614,448 | $274.4M | 0.18% | −40,022−6.1% | Reduced |
| UBS Group AG | 630,618 | $281.6M | 0.05% | +74,636+13.4% | Added |
| Arrowstreet Capital, Limited Partnership | 638,950 | $285.3M | 0.15% | +45,003+7.6% | Added |
| HSBC Holdings PLC | 655,443 | $292.7M | 0.17% | +25,154+4.0% | Added |
| Barclays PLC | 663,263 | $296.2M | 0.11% | −184,495−21.8% | Reduced |
| Bellevue Group AG | 681,908 | $304.5M | 7.25% | +788+0.1% | Added |
| Citigroup Inc | 682,807 | $304.9M | 0.19% | +142,877+26.5% | Added |
| Swiss National Bank | 744,600 | $332.5M | 0.19% | +42,000+6.0% | Added |
| Wells Fargo & Company | 744,995 | $332.7M | 0.07% | +3,182+0.4% | Added |
| American Century Companies Inc | 813,285 | $363.2M | 0.19% | −35,354−4.2% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 848,047 | $378.7M | 0.44% | +178,240+26.6% | Added |
| Edgewood Management LLC | 905,129 | $404.2M | 2.61% | −154,946−14.6% | Reduced |
| Dimensional Fund Advisors LP | 989,342 | $441.8M | 0.09% | +43,682+4.6% | Added |
| Nuveen, LLC | 1,084,495 | $484.3M | 0.13% | +42,098+4.0% | Added |
| Royal Bank of Canada | 1,111,871 | $496.5M | 0.09% | −82,641−6.9% | Reduced |
| WCM Investment Management, LLC | 1,121,341 | $496.9M | 1.13% | −7,804−0.7% | Reduced |
| Vanguard Fiduciary Trust Co | 1,465,724 | $654.5M | 0.17% | +1,465,724 | New |
| Amundi | 1,472,496 | $657.5M | 0.18% | +168,335+12.9% | Added |
| Deutsche Bank AG | 1,537,736 | $686.7M | 0.23% | −231,145−13.1% | Reduced |
| Bank of New York Mellon Corp | 1,586,427 | $708.4M | 0.13% | +58,841+3.9% | Added |
| Price T Rowe Associates Inc | 1,760,122 | $786.0M | 0.09% | −518,836−22.8% | Reduced |
| Victory Capital Management Inc | 1,888,521 | $843.3M | 0.54% | −1,468,245−43.7% | Reduced |
| Charles Schwab Investment Management Inc | 1,920,871 | $857.7M | 0.13% | +61,650+3.3% | Added |
| Legal & General Group Plc | 1,955,764 | $873.3M | 0.20% | −14,341−0.7% | Reduced |
| FMR LLC | 2,020,265 | $902.1M | 0.05% | −192,331−8.7% | Reduced |
| Janus Henderson Group PLC | 2,131,527 | $951.8M | 0.45% | −90,426−4.1% | Reduced |
| Goldman Sachs Group Inc | 2,417,875 | $1.08B | 0.14% | +663,757+37.8% | Added |
| Northern Trust Corp | 2,564,264 | $1.15B | 0.15% | −15,193−0.6% | Reduced |
| Ameriprise Financial Inc | 2,633,481 | $1.18B | 0.27% | +369,749+16.3% | Added |
| Clearbridge Investments, LLC | 2,700,975 | $1.21B | 1.05% | −159,201−5.6% | Reduced |
| Jennison Associates LLC | 2,740,059 | $1.22B | 0.84% | −509,482−15.7% | Reduced |
| Bank of America Corp | 2,878,183 | $1.29B | 0.09% | −58,847−2.0% | Reduced |
| UBS Asset Management Americas Inc | 3,057,396 | $1.37B | 0.28% | +56,618+1.9% | Added |
| Morgan Stanley | 3,188,881 | $1.42B | 0.09% | +68,571+2.2% | Added |
| Wellington Management Group LLP | 3,212,589 | $1.43B | 0.27% | −609,142−15.9% | Reduced |
| Alliancebernstein L.P. | 3,910,786 | $1.77B | 0.57% | −585,696−13.0% | Reduced |
| Loomis Sayles & Co L P | 4,003,821 | $1.79B | 2.41% | −29,704−0.7% | Reduced |
| Capital International Investors | 5,126,077 | $2.29B | 0.54% | +392,481+8.3% | Added |
| Vanguard Portfolio Management LLC | 5,145,609 | $2.30B | 0.12% | +5,145,609 | New |
| Geode Capital Management, LLC | 6,139,621 | $2.73B | 0.17% | +157,716+2.6% | Added |
| JPMorgan Chase & Co | 7,033,156 | $3.12B | 0.21% | +993,675+16.5% | Added |
| Invesco Ltd. | 7,892,611 | $3.52B | 0.34% | +39,878+0.5% | Added |
| State Street Corp | 11,730,139 | $5.24B | 0.18% | +40,600+0.3% | Added |
| Vanguard Capital Management LLC | 16,512,810 | $7.37B | 0.18% | +16,512,810 | New |
| Capital Research Global Investors | 21,125,964 | $9.43B | 1.46% | +3,809,620+22.0% | Added |
| BlackRock, Inc. | 23,969,517 | $10.7B | 0.19% | +217,528+0.9% | Added |
| Capital World Investors | 25,368,124 | $11.3B | 1.55% | −142,058−0.6% | Reduced |
| Winslow Capital Management, LLC | 0 | $0 | 0.00% | −887,640−100.0% | Sold out |
| Alyeska Investment Group, L.P. | 0 | $0 | 0.00% | −354,334−100.0% | Sold out |