Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Handelsbanken Fonder AB | 216,331 | $98.1M | 0.30% | +1,571+0.7% | Added |
| Aviva PLC | 216,211 | $98.0M | 0.17% | +11,322+5.5% | Added |
| Massachusetts Financial Services Co | 211,934 | $96.1M | 0.03% | −291,226−57.9% | Reduced |
| Davenport & Co LLC | 211,577 | $95.9M | 0.52% | −5,707−2.6% | Reduced |
| New York State Teachers Retirement System | 211,092 | $95.7M | 0.19% | −1,737−0.8% | Reduced |
| Marshall Wace, LLP | 204,032 | $92.5M | 0.09% | +158,147+344.7% | Added |
| Canada Pension Plan Investment Board | 202,333 | $91.7M | 0.06% | −44,031−17.9% | Reduced |
| First Trust Advisors LP | 201,290 | $91.3M | 0.07% | +13,129+7.0% | Added |
| Baillie Gifford & Co | 201,088 | $91.2M | 0.08% | −5,968−2.9% | Reduced |
| Lazard Asset Management LLC | 198,950 | $90.2M | 0.15% | −345,873−63.5% | Reduced |
| Capital International Sarl | 193,438 | $87.7M | 1.41% | −32,296−14.3% | Reduced |
| Korea Investment CORP | 193,435 | $87.7M | 0.17% | −12,310−6.0% | Reduced |
| Carmignac Gestion | 191,571 | $86.9M | 1.17% | +4,032+2.1% | Added |
| Great West Life Assurance Co | 187,604 | $85.1M | 0.15% | −86,532−31.6% | Reduced |
| TD Asset Management Inc | 182,613 | $82.8M | 0.07% | −34,926−16.1% | Reduced |
| Nomura Asset Management International Inc. | 178,365 | $80.9M | 0.12% | +178,365 | New |
| Skandinaviska Enskilda Banken AB (publ) | 174,466 | $79.1M | 0.32% | +20,218+13.1% | Added |
| Mirae Asset Global Investments Co., Ltd. | 174,347 | $79.0M | 0.22% | +23,291+15.4% | Added |
| Mirae Asset Global ETFs Holdings Ltd. | 170,775 | $77.2M | 0.12% | +4,830+2.9% | Added |
| Sofinnova Investments, Inc. | 164,594 | $74.6M | 3.22% | +46,719+39.6% | Added |
| Hudson Bay Capital Management LP | 164,518 | $74.6M | 0.43% | +119,203+263.1% | Added |
| Groupama Asset Managment | 163,144 | $74.0M | 1.08% | +119,763+276.1% | Added |
| Mitsubishi UFJ Trust & Banking Corp | 162,206 | $73.5M | 0.17% | +12,351+8.2% | Added |
| APG Asset Management N.V. | 188,385 | $72.7M | 0.21% | −12,203−6.1% | Reduced |
| Capital International Inc | 159,660 | $72.4M | 0.57% | −31,681−16.6% | Reduced |
| Danske Bank A/S | 157,165 | $71.3M | 0.17% | −7,315−4.4% | Reduced |
| ABN AMRO Bank N.V. | 155,221 | $70.1M | 0.66% | +13,350+9.4% | Added |
| Birch Hill Investment Advisors LLC | 152,485 | $69.1M | 2.89% | −1,117−0.7% | Reduced |
| Stifel Financial Corp | 152,447 | $69.1M | 0.06% | +9,918+7.0% | Added |
| Asset Management One Co.,Ltd. | 150,106 | $69.0M | 0.19% | +3,242+2.2% | Added |
| Van Eck Associates Corp | 149,451 | $67.8M | 0.06% | +395+0.3% | Added |
| Provident Investment Management, Inc. | 149,258 | $67.7M | 6.16% | −4,148−2.7% | Reduced |
| NEOS Investment Management LLC | 146,198 | $66.3M | 0.38% | +32,665+28.8% | Added |
| AMF Pensionsforsakring AB | 145,949 | $66.2M | 0.41% | +83,487+133.7% | Added |
| AQR Capital Management LLC | 143,651 | $65.1M | 0.03% | −18,032−11.2% | Reduced |
| KBC Group NV | 141,120 | $64.0M | 0.15% | +7,518+5.6% | Added |
| State of Wisconsin Investment Board | 137,909 | $62.5M | 0.14% | −10,440−7.0% | Reduced |
| PFA Pension, Forsikringsaktieselskab | 135,188 | $61.3M | 0.17% | +135,188 | New |
| Rockefeller Capital Management L.P. | 135,232 | $61.3M | 0.11% | +42,418+45.7% | Added |
| Prudential Financial Inc | 134,619 | $61.0M | 0.07% | −91,195−40.4% | Reduced |
| Bowen Hanes & Co Inc | 133,504 | $60.5M | 1.52% | +9,070+7.3% | Added |
| Intermede Investment Partners Ltd | 133,378 | $60.5M | 2.48% | −6,645−4.7% | Reduced |
| Colony Group, LLC | 132,846 | $60.2M | 0.07% | −6,369−4.6% | Reduced |
| Tredje AP-fonden | 131,727 | $59.7M | 0.45% | −53,585−28.9% | Reduced |
| Mariner, LLC | 128,465 | $58.2M | 0.07% | +18,214+16.5% | Added |
| Woodline Partners LP | 127,726 | $57.9M | 0.22% | −25,546−16.7% | Reduced |
| Truist Financial Corp | 126,193 | $57.2M | 0.08% | −17,671−12.3% | Reduced |
| Schroder Investment Management Group | 123,252 | $55.9M | 0.04% | +1,665+1.4% | Added |
| Allspring Global Investments Holdings, LLC | 122,210 | $55.3M | 0.09% | −4,653−3.7% | Reduced |
| Nomura Asset Management Co Ltd | 119,698 | $54.3M | 0.14% | +7,365+6.6% | Added |
| DnB Asset Management AS | 119,685 | $54.3M | 0.19% | +24,271+25.4% | Added |
| SG Americas Securities, LLC | 115,899 | $52.5M | 0.07% | +55,837+93.0% | Added |
| Caisse de Depot Et Placement du Quebec | 113,768 | $51.6M | 0.09% | −108,494−48.8% | Reduced |
| Balyasny Asset Management LLC | 113,488 | $51.5M | 0.10% | +113,488 | New |
| Raiffeisen Bank International AG | 112,645 | $51.1M | 0.66% | +540.0% | Added |
| Teacher Retirement System of Texas | 111,010 | $50.3M | 0.17% | −7,638−6.4% | Reduced |
| Storebrand Asset Management AS | 109,573 | $49.7M | 0.13% | −2,295−2.1% | Reduced |
| Worldquant Millennium Advisors LLC | 108,002 | $49.0M | 0.19% | +108,002 | New |
| Treasurer of the State of North Carolina | 107,758 | $48.9M | 0.16% | −7,871−6.8% | Reduced |
| CIBC Asset Management Inc | 107,641 | $48.8M | 0.12% | +26,636+32.9% | Added |
| Vontobel Holding Ltd. | 105,287 | $47.7M | 0.16% | −5,355−4.8% | Reduced |
| Public Employees Retirement System of Ohio | 102,663 | $46.5M | 0.15% | −69−0.1% | Reduced |
| CI Private Wealth, LLC | 102,570 | $46.5M | 0.06% | +839+0.8% | Added |
| Guggenheim Capital LLC | 101,041 | $45.8M | 0.34% | −2,084−2.0% | Reduced |
| Country Trust Bank | 100,593 | $45.6M | 0.83% | +2,061+2.1% | Added |
| Creative Planning | 100,513 | $45.6M | 0.03% | +5,649+6.0% | Added |
| Kovitz Investment Group Partners, LLC | 98,375 | $44.6M | 0.99% | +17,788+22.1% | Added |
| Two Sigma Advisers, LP | 98,360 | $44.6M | 0.09% | +86,860+755.3% | Added |
| Banco Santander, S.A. | 98,027 | $44.4M | 0.33% | +18,621+23.5% | Added |
| Bank of Nova Scotia | 97,920 | $44.4M | 0.07% | +11,668+13.5% | Added |
| Capital International Ltd | 95,612 | $43.3M | 1.53% | −25,675−21.2% | Reduced |
| Banco Bilbao Vizcaya Argentaria, S.A. | 93,837 | $42.6M | 0.30% | −4,316−4.4% | Reduced |
| KLP Kapitalforvaltning AS | 92,901 | $42.1M | 0.16% | +260+0.3% | Added |
| Quantinno Capital Management LP | 92,284 | $41.8M | 0.08% | +36,643+65.9% | Added |
| Lansforsakringar Fondforvaltning AB (publ) | 91,826 | $41.6M | 0.21% | −54,737−37.3% | Reduced |
| Toronto Dominion Bank | 91,288 | $41.4M | 0.07% | −13,590−13.0% | Reduced |
| Assetmark, Inc | 90,483 | $41.0M | 0.08% | +633+0.7% | Added |
| Resona Asset Management Co.,Ltd. | 89,399 | $40.6M | 0.20% | −2,699−2.9% | Reduced |
| Fjarde Ap-Fonden /Fourth Swedish National Pension Fund | 89,062 | $40.4M | 0.34% | −560−0.6% | Reduced |
| State of New Jersey Common Pension Fund D | 87,835 | $39.8M | 0.14% | −2,294−2.5% | Reduced |
| Healthcare of Ontario Pension Plan Trust Fund | 87,728 | $39.8M | 0.07% | +3,882+4.6% | Added |
| Susquehanna International Group, LLP | 84,096 | $38.1M | 0.05% | +16,413+24.2% | Added |
| Wealth Enhancement Advisory Services, LLC | 81,246 | $38.1M | 0.05% | +7,777+10.6% | Added |
| State of Tennessee, Treasury Department | 80,373 | $37.8M | 0.12% | −6,388−7.4% | Reduced |
| ING Groep NV | 81,129 | $36.8M | 0.22% | +69,140+576.7% | Added |
| Tang Capital Management LLC | 80,000 | $36.3M | 1.79% | 00.0% | Unchanged |
| STRS Ohio | 78,278 | $35.5M | 0.13% | −2,347−2.9% | Reduced |
| Federated Hermes, Inc. | 77,661 | $35.2M | 0.06% | −108,908−58.4% | Reduced |
| Eurizon Capital SGR S.p.A. | 77,394 | $35.1M | 0.11% | +77,394 | New |
| Iron Triangle Partners LP | 76,910 | $34.9M | 3.99% | +76,910 | New |
| Thrivent Financial for Lutherans | 76,687 | $34.8M | 0.06% | −1,583−2.0% | Reduced |
| Pacer Advisors, Inc. | 76,142 | $34.5M | 0.09% | +9,641+14.5% | Added |
| Cetera Investment Advisers | 75,013 | $34.0M | 0.04% | −2,701−3.5% | Reduced |
| Beacon Investment Advisory Services, Inc. | 74,093 | $33.6M | 1.37% | −2,049−2.7% | Reduced |
| MetLife Investment Management | 73,281 | $33.2M | 0.16% | −2,526−3.3% | Reduced |
| Swiss Life Asset Management Ltd | 73,018 | $33.1M | 0.17% | +9,073+14.2% | Added |
| Arizona State Retirement System | 72,293 | $32.8M | 0.18% | −2,701−3.6% | Reduced |
| Daiwa Securities Group Inc. | 70,595 | $32.0M | 0.10% | +3,368+5.0% | Added |
| Janney Montgomery Scott LLC | 70,353 | $31.9M | 0.07% | −7,103−9.2% | Reduced |
| Nissay Asset Management Corp | 69,627 | $31.6M | 0.16% | +2,970+4.5% | Added |