Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Cherry Creek Investment Advisors, Inc. | 1,400 | $634.7K | 0.27% | −722−34.0% | Reduced |
| Conning Inc. | 1,400 | $634.7K | 0.02% | −144−9.3% | Reduced |
| Alpine Woods Capital Investors, LLC | 1,402 | $635.6K | 0.15% | −3,019−68.3% | Reduced |
| TCG Advisory Services, LLC | 1,406 | $637.4K | 0.02% | +361+34.5% | Added |
| Mayflower Financial Advisors, LLC | 1,408 | $638.3K | 0.08% | +155+12.4% | Added |
| BankChampaign, National Association | 1,409 | $638.8K | 0.63% | +1,409 | New |
| First Pacific Financial | 1,412 | $640.1K | 0.08% | −39−2.7% | Reduced |
| Great Diamond Partners, LLC | 1,416 | $642.0K | 0.12% | +44+3.2% | Added |
| S-Bank Fund Management Ltd | 1,428 | $647.4K | 0.08% | −776−35.2% | Reduced |
| Renaissance Group LLC | 1,433 | $649.6K | 0.03% | −35−2.4% | Reduced |
| Arcataur Capital Management LLC | 1,434 | $650.1K | 0.19% | −5−0.3% | Reduced |
| Journey Strategic Wealth LLC | 1,441 | $653.3K | 0.02% | +487+51.0% | Added |
| Bradley Foster & Sargent Inc | 1,442 | $653.7K | 0.01% | −301−17.3% | Reduced |
| Koshinski Asset Management, Inc. | 1,456 | $660.1K | 0.04% | +117+8.7% | Added |
| Spinnaker Trust | 1,458 | $661.0K | 0.04% | −47−3.1% | Reduced |
| Polymer Capital Management (US) LLC | 1,460 | $661.9K | 0.09% | −622−29.9% | Reduced |
| IHT Wealth Management, LLC | 1,463 | $663.3K | 0.02% | −79−5.1% | Reduced |
| Baxter Bros Inc | 1,464 | $663.7K | 0.08% | −85−5.5% | Reduced |
| LVW Advisors, LLC | 1,474 | $668.3K | 0.07% | +503+51.8% | Added |
| Holocene Advisors, LP | 1,478 | $670.1K | 0.00% | +1,478 | New |
| Legacy Wealth Asset Management, LLC | 1,483 | $672.3K | 0.17% | +41+2.8% | Added |
| Alpha Family Trust | 1,485 | $673.2K | 0.31% | 00.0% | Unchanged |
| Virtu Financial LLC | 1,493 | $676.0K | 0.03% | +1,493 | New |
| STF Management LP | 1,494 | $677.3K | 0.64% | −2,492−62.5% | Reduced |
| Strategic Investment Advisors | 1,511 | $685.0K | 0.06% | −139−8.4% | Reduced |
| Virtus Investment Advisers, Inc. | 1,511 | $685.0K | 0.19% | +545+56.4% | Added |
| Pinnacle Wealth Planning Services, Inc. | 1,518 | $688.0K | 0.07% | +138+10.0% | Added |
| Oxford Asset Management LLP | 1,522 | $690.0K | 0.24% | +1,522 | New |
| National Wealth Management Group, LLC | 1,529 | $693.2K | 0.24% | +1,529 | New |
| Destination Wealth Management | 1,538 | $697.3K | 0.02% | −104−6.3% | Reduced |
| Lantern Wealth Advisors, LLC | 1,550 | $702.7K | 0.37% | 00.0% | Unchanged |
| LOM Asset Management Ltd | 1,565 | $709.5K | 0.21% | 00.0% | Unchanged |
| Wealth Alliance | 1,565 | $709.5K | 0.07% | +306+24.3% | Added |
| Resonant Capital Advisors, LLC | 1,566 | $710.0K | 0.04% | +102+7.0% | Added |
| Summit Financial, LLC | 1,567 | $710.4K | 0.01% | −76−4.6% | Reduced |
| Sava Infond d.o.o. | 1,570 | $711.8K | 0.10% | 00.0% | Unchanged |
| KRS Capital Management, LLC | 1,572 | $712.7K | 0.41% | 00.0% | Unchanged |
| Flagship Harbor Advisors, LLC | 1,573 | $713.1K | 0.03% | −17−1.1% | Reduced |
| Kensington Investment Counsel, LLC | 1,574 | $713.6K | 0.29% | +48+3.1% | Added |
| Csenge Advisory Group | 1,576 | $714.3K | 0.03% | −216−12.1% | Reduced |
| Perfromance Wealth Partners, LLC | 1,600 | $725.4K | 0.02% | −5−0.3% | Reduced |
| Peapack Gladstone Financial Corp | 1,604 | $727.0K | 0.01% | −7−0.4% | Reduced |
| Diversified Enterprises, LLC | 1,607 | $728.5K | 0.04% | +1,607 | New |
| Mitchell McLeod Pugh & Williams Inc | 1,537 | $734.6K | 0.10% | +800+108.5% | Added |
| Campbell Newman Asset Management Inc | 1,622 | $735.4K | 0.05% | −12−0.7% | Reduced |
| Alta Wealth Advisors LLC | 1,625 | $736.7K | 0.25% | +29+1.8% | Added |
| Oxler Private Wealth LLC | 1,632 | $739.9K | 0.21% | 00.0% | Unchanged |
| Continuum Advisory, LLC | 1,632 | $739.9K | 0.07% | +86+5.6% | Added |
| Perpetual Ltd | 1,636 | $741.7K | 0.01% | +1,636 | New |
| Abacus Wealth Partners, LLC | 1,638 | $742.6K | 0.07% | +1,638 | New |
| Vista Investment Management | 1,649 | $747.6K | 0.25% | +1+0.1% | Added |
| Advisors Capital Management, LLC | 1,652 | $749.1K | 0.01% | +100+6.4% | Added |
| Drive Wealth Management, LLC | 1,653 | $749.2K | 0.15% | +203+14.0% | Added |
| Roman Butler Fullerton & Co | 1,604 | $749.5K | 0.20% | +10+0.6% | Added |
| Sigma Planning Corp | 1,686 | $764.3K | 0.02% | +54+3.3% | Added |
| Blue Chip Partners, Inc. | 1,691 | $766.6K | 0.06% | +316+23.0% | Added |
| Larry Mathis Financial Planning, LLC | 1,693 | $767.5K | 0.68% | +1,693 | New |
| Global Assets Advisory, LLC | 1,694 | $768.0K | 0.22% | +130+8.3% | Added |
| Raab & Moskowitz Asset Management LLC | 1,701 | $771.2K | 0.17% | 00.0% | Unchanged |
| Claro Advisors LLC | 1,705 | $772.9K | 0.11% | −13−0.8% | Reduced |
| Triangle Securities Wealth Management | 1,709 | $774.8K | 0.16% | −27−1.6% | Reduced |
| Fifth Third Wealth Advisors LLC | 1,714 | $777.1K | 0.03% | −86−4.8% | Reduced |
| Montis Financial, LLC | 1,723 | $781.1K | 0.15% | −476−21.6% | Reduced |
| Legacy Capital Wealth Partners, LLC | 1,727 | $783.0K | 0.17% | +224+14.9% | Added |
| Savvy Advisors, Inc. | 1,760 | $797.9K | 0.03% | +341+24.0% | Added |
| Kane Investment Management, Inc. | 1,768 | $801.5K | 0.39% | 00.0% | Unchanged |
| Reuter James Wealth Management, LLC | 1,768 | $801.5K | 0.11% | +109+6.6% | Added |
| Quadcap Wealth Management, LLC | 1,790 | $811.5K | 0.09% | +453+33.9% | Added |
| Acima Private Wealth, LLC | 1,806 | $818.8K | 0.25% | 00.0% | Unchanged |
| Premier Path Wealth Partners, LLC | 1,808 | $819.9K | 0.11% | +118+7.0% | Added |
| Appleton Partners Inc | 1,808 | $820.0K | 0.05% | 00.0% | Unchanged |
| Formidable Asset Management, LLC | 1,911 | $822.9K | 0.12% | −76−3.8% | Reduced |
| Altfest L J & Co Inc | 1,824 | $826.9K | 0.09% | +67+3.8% | Added |
| Wealthspire Advisors, LLC | 1,825 | $827.2K | 0.01% | +1,382+312.0% | Added |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 1,831 | $830.1K | 0.01% | +156+9.3% | Added |
| Ameritas Advisory Services, LLC | 1,842 | $835.1K | 0.03% | +1,663+929.1% | Added |
| TD Private Client Wealth LLC | 1,843 | $835.6K | 0.02% | +52+2.9% | Added |
| OpenArc Corporate Advisory, LLC | 1,845 | $836.4K | 0.01% | +1,845 | New |
| Guidance Capital, Inc | 1,797 | $839.8K | 0.21% | +167+10.2% | Added |
| Goelzer Investment Management, Inc. | 1,870 | $847.8K | 0.04% | +4+0.2% | Added |
| Howland Capital Management LLC | 1,879 | $851.9K | 0.03% | −39−2.0% | Reduced |
| Livforsakringsbolaget Skandia, Omsesidigt | 1,880 | $852.3K | 0.03% | 00.0% | Unchanged |
| Badgley Phelps Wealth Managers, LLC | 1,887 | $855.5K | 0.02% | 00.0% | Unchanged |
| Gryphon Financial Partners LLC | 1,895 | $859.1K | 0.09% | −12−0.6% | Reduced |
| Great Lakes Retirement, Inc. | 1,909 | $865.5K | 0.09% | +120+6.7% | Added |
| Twin Capital Management Inc | 1,919 | $870.0K | 0.11% | +14+0.7% | Added |
| CX Institutional | 1,938 | $879.0K | 0.03% | +132+7.3% | Added |
| Rehmann Capital Advisory Group | 1,937 | $879.1K | 0.05% | +61+3.3% | Added |
| IFG Advisory, LLC | 1,941 | $880.0K | 0.04% | 00.0% | Unchanged |
| Baker Ellis Asset Management LLC | 1,952 | $885.0K | 0.11% | 00.0% | Unchanged |
| Spire Wealth Management | 1,955 | $886.3K | 0.03% | −381−16.3% | Reduced |
| Spears Abacus Advisors LLC | 1,960 | $888.6K | 0.02% | 00.0% | Unchanged |
| Annis Gardner Whiting Capital Advisors, LLC | 1,964 | $890.4K | 0.17% | −3−0.2% | Reduced |
| Pensionmark Financial Group, LLC | 1,972 | $894.2K | 0.01% | +541+37.8% | Added |
| Breakwater Capital Group | 1,975 | $895.4K | 0.12% | +14+0.7% | Added |
| SRS Capital Advisors, Inc. | 1,976 | $895.7K | 0.03% | +337+20.6% | Added |
| Principal Street Partners, LLC | 1,985 | $899.9K | 0.15% | −360−15.4% | Reduced |
| Umb Bank N A | 1,986 | $900.4K | 0.01% | +148+8.1% | Added |
| Sage Mountain Advisors LLC | 1,997 | $905.2K | 0.05% | −11−0.5% | Reduced |
| Mystic Asset Management, Inc. | 2,000 | $906.7K | 0.21% | 00.0% | Unchanged |