Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sunbelt Securities, Inc. | 1,026 | $465.1K | 0.03% | −12−1.2% | Reduced |
| Flow Traders U.S. LLC | 1,029 | $467.0K | 0.02% | +1,029 | New |
| Parsonex Advisory Services, Inc. | 1,031 | $467.4K | 0.30% | +13+1.3% | Added |
| Optas, LLC | 1,035 | $469.2K | 0.07% | +271+35.5% | Added |
| Investment Management Corp | 1,043 | $472.7K | 0.40% | +16+1.6% | Added |
| Ramiah Investment Group | 1,044 | $473.3K | 0.41% | +74+7.6% | Added |
| Guardian Wealth Advisors, LLC | 1,053 | $477.2K | 0.03% | +2+0.2% | Added |
| Jacobi Capital Management LLC | 1,061 | $481.0K | 0.03% | +19+1.8% | Added |
| EntryPoint Capital, LLC | 1,066 | $483.3K | 0.19% | +1,066 | New |
| Independent Financial Group, LLC | 1,069 | $484.6K | 0.01% | −122−10.2% | Reduced |
| Albion Financial Group | 1,077 | $488.3K | 0.03% | −32−2.9% | Reduced |
| Cynosure Management, LLC | 1,079 | $489.2K | 0.05% | +161+17.5% | Added |
| Optimize Financial Inc | 1,084 | $491.4K | 0.25% | +12+1.1% | Added |
| NorthCrest Asset Manangement, LLC | 1,095 | $491.5K | 0.01% | −271−19.8% | Reduced |
| NorthRock Partners, LLC | 1,085 | $492.0K | 0.01% | −2,367−68.6% | Reduced |
| Larson Financial Group LLC | 1,087 | $492.8K | 0.02% | +224+26.0% | Added |
| EverSource Wealth Advisors, LLC | 1,091 | $494.3K | 0.02% | +159+17.1% | Added |
| Invesco, LLC | 1,091 | $494.6K | 0.17% | 00.0% | Unchanged |
| Harbor Investment Advisory, LLC | 1,094 | $496.0K | 0.04% | −59−5.1% | Reduced |
| Bridgewater Advisors Inc. | 1,076 | $496.3K | 0.03% | +7+0.7% | Added |
| Fairfield Financial Advisors, LTD | 1,098 | $497.8K | 0.16% | +355+47.8% | Added |
| Founders Financial Alliance, LLC | 1,101 | $499.1K | 0.09% | +56+5.4% | Added |
| Sage Capital Advisors,llc | 1,104 | $500.3K | 0.12% | +53+5.0% | Added |
| Moneta Group Investment Advisors LLC | 1,107 | $501.9K | 0.00% | −70−5.9% | Reduced |
| Regions Financial Corp | 1,109 | $502.8K | 0.00% | +462+71.4% | Added |
| WBI Investments | 1,114 | $505.0K | 0.13% | +1,114 | New |
| Westfield Capital Management Co LP | 1,132 | $513.2K | 0.00% | +1,132 | New |
| First Commonwealth Financial Corp | 1,134 | $514.0K | 0.08% | −1−0.1% | Reduced |
| Davis R M Inc | 1,135 | $514.4K | 0.01% | +360+46.5% | Added |
| LCM Capital Management Inc | 1,135 | $514.6K | 0.25% | −10−0.9% | Reduced |
| Legato Capital Management LLC | 1,141 | $517.3K | 0.04% | +1,141 | New |
| SmartHarvest Portfolios, LLC | 1,142 | $517.7K | 0.18% | +1,142 | New |
| Second Line Capital, LLC | 1,144 | $518.6K | 0.11% | +29+2.6% | Added |
| Resurgent Financial Advisors LLC | 1,149 | $520.9K | 0.26% | +1,149 | New |
| Meadowbrook Advisors Group, LLC | 1,151 | $521.8K | 0.29% | +1,151 | New |
| Tobam | 1,154 | $523.0K | 0.13% | +1,154 | New |
| Venture Visionary Partners LLC | 1,154 | $523.2K | 0.02% | +197+20.6% | Added |
| Williams Jones Wealth Management, LLC. | 1,155 | $523.6K | 0.01% | +21+1.9% | Added |
| Wrapmanager Inc | 1,156 | $524.1K | 0.18% | −23−2.0% | Reduced |
| Redhawk Wealth Advisors, Inc. | 1,156 | $524.1K | 0.06% | +46+4.1% | Added |
| DGS Capital Management, LLC | 1,161 | $526.4K | 0.09% | +307+35.9% | Added |
| Keynote Financial Services LLC | 1,166 | $528.6K | 0.30% | +12+1.0% | Added |
| Angeles Wealth Management, LLC | 1,168 | $529.5K | 0.03% | +164+16.3% | Added |
| Capital Investment Advisors, LLC | 1,171 | $530.9K | 0.01% | +162+16.1% | Added |
| Natural Investments, LLC | 1,173 | $531.0K | 0.13% | +225+23.7% | Added |
| Paladin Wealth, LLC | 1,175 | $532.7K | 0.36% | −62−5.0% | Reduced |
| Total Clarity Wealth Management, Inc. | 1,183 | $536.3K | 0.13% | −49−4.0% | Reduced |
| Weatherly Asset Management L. P. | 1,184 | $536.8K | 0.04% | −347−22.7% | Reduced |
| Towarzystwo Funduszy Inwestycyjnych Pzu SA | 1,189 | $539.0K | 0.14% | 00.0% | Unchanged |
| Davy Global Fund Management Ltd | 1,191 | $540.0K | 0.04% | +339+39.8% | Added |
| Graham Capital Management, L.P. | 1,193 | $540.9K | 0.02% | +1,193 | New |
| 71 West Capital Partners | 1,200 | $544.0K | 0.03% | +1,200 | New |
| Portfolio Design Labs, LLC | 1,205 | $546.3K | 0.09% | +316+35.5% | Added |
| BridgePort Financial Solutions, LLC | 1,209 | $548.1K | 0.15% | +218+22.0% | Added |
| BIP Wealth, LLC | 1,215 | $550.8K | 0.02% | +1,215 | New |
| Keel Point, LLC | 1,216 | $551.1K | 0.03% | +85+7.5% | Added |
| St. Louis Trust Co | 1,218 | $552.2K | 0.06% | +1,218 | New |
| Catalytic Wealth RIA, LLC | 1,222 | $554.0K | 0.02% | −2,110−63.3% | Reduced |
| Montecito Bank & Trust | 1,227 | $556.3K | 0.09% | −1,012−45.2% | Reduced |
| J.W. Cole Advisors, Inc. | 1,323 | $558.5K | 0.01% | −164−11.0% | Reduced |
| Private Wealth Partners, LLC | 1,235 | $559.9K | 0.04% | 00.0% | Unchanged |
| Rathbone Brothers plc | 1,244 | $564.0K | 0.00% | 00.0% | Unchanged |
| Lecap Asset Management Ltd | 1,245 | $564.4K | 0.22% | +1,245 | New |
| Green Harvest Asset Management LLC | 1,246 | $564.9K | 0.01% | −2−0.2% | Reduced |
| Fragasso Group Inc. | 1,248 | $565.8K | 0.03% | −9−0.7% | Reduced |
| Merrion Investment Management Co, LLC | 1,250 | $566.7K | 0.31% | 00.0% | Unchanged |
| Churchill Financial Advisors, LLC | 1,250 | $566.7K | 0.17% | +1,250 | New |
| BOK Financial Private Wealth, Inc. | 1,262 | $572.1K | 0.04% | −17−1.3% | Reduced |
| Gibbs Wealth Management | 1,235 | $572.9K | 0.14% | +19+1.6% | Added |
| One Wealth Capital Management, LLC | 1,266 | $574.0K | 0.24% | +268+26.9% | Added |
| Kingswood Wealth Advisors, LLC | 1,276 | $578.5K | 0.03% | +1,276 | New |
| Wakefield Asset Management LLLP | 1,276 | $578.5K | 0.16% | 00.0% | Unchanged |
| Modern Wealth Management, LLC | 1,280 | $580.1K | 0.01% | +114+9.8% | Added |
| Insigneo Advisory Services, LLC | 1,285 | $582.6K | 0.04% | −7−0.5% | Reduced |
| Paces Ferry Wealth Advisors, LLC | 1,286 | $583.0K | 0.24% | −21−1.6% | Reduced |
| Accurate Wealth Management, LLC | 1,262 | $585.5K | 0.07% | +83+7.0% | Added |
| SageView Advisory Group, LLC | 1,302 | $590.3K | 0.02% | −1,995−60.5% | Reduced |
| Quadrature Capital Ltd | 1,303 | $590.7K | 0.01% | −148,605−99.1% | Reduced |
| Platform Technology Partners | 1,304 | $591.2K | 0.13% | +70+5.7% | Added |
| PDS Planning, Inc | 1,317 | $597.1K | 0.04% | +174+15.2% | Added |
| Frec Markets, Inc. | 1,317 | $597.4K | 0.17% | +1,317 | New |
| SBI Securities Co., Ltd. | 1,319 | $598.0K | 0.02% | −127−8.8% | Reduced |
| Hancock Whitney Corp | 1,326 | $601.1K | 0.01% | −13−1.0% | Reduced |
| Catalyst Financial Partners LLC | 1,332 | $603.9K | 0.07% | +218+19.6% | Added |
| Ronald Blue Trust, Inc. | 1,337 | $606.3K | 0.01% | +769+135.4% | Added |
| Bannerstone Capital Management, LLC | 1,342 | $608.4K | 0.58% | +1,342 | New |
| 1248 Management, LLC | 1,343 | $608.9K | 0.33% | +62+4.8% | Added |
| Personal Cfo Solutions, LLC | 1,344 | $609.3K | 0.10% | +165+14.0% | Added |
| Nabity-Jensen Investment Management Inc | 1,348 | $611.1K | 0.41% | 00.0% | Unchanged |
| Pine Valley Investments Ltd Liability Co | 1,350 | $612.0K | 0.03% | 00.0% | Unchanged |
| Evoke Wealth, LLC | 1,354 | $613.8K | 0.01% | +342+33.8% | Added |
| Avidian Wealth Solutions, LLC | 1,354 | $613.9K | 0.02% | +97+7.7% | Added |
| BankPlus Trust Department | 1,356 | $614.8K | 0.16% | +33+2.5% | Added |
| Perennial Investment Advisors, LLC | 1,359 | $615.7K | 0.05% | +96+7.6% | Added |
| Groesbeck Investment Management Corp | 1,359 | $616.0K | 1.16% | 00.0% | Unchanged |
| Abel Hall, LLC | 1,360 | $616.6K | 0.14% | +1,360 | New |
| Kessler Investment Group, LLC | 1,373 | $622.5K | 0.26% | 00.0% | Unchanged |
| Checchi Capital Advisers, LLC | 1,385 | $627.9K | 0.04% | −76−5.2% | Reduced |
| Prosperity Consulting Group, LLC | 1,393 | $631.5K | 0.03% | −1,655−54.3% | Reduced |
| Fukoku Mutual Life Insurance Co | 1,397 | $633.3K | 0.04% | −192−12.1% | Reduced |