Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Massachusetts Wealth Management | 722 | $327.3K | 0.15% | 00.0% | Unchanged |
| David Loasby | 711 | $327.5K | 0.02% | −124−14.9% | Reduced |
| Turtle Creek Wealth Advisors, LLC | 723 | $327.8K | 0.03% | +70+10.7% | Added |
| Castleark Management LLC | 730 | $331.0K | 0.01% | 00.0% | Unchanged |
| Childress Capital Advisors, LLC | 730 | $331.1K | 0.05% | +22+3.1% | Added |
| GK Wealth Management LLC | 732 | $331.9K | 0.24% | −35−4.6% | Reduced |
| Nicholas Hoffman & Company, LLC. | 732 | $331.9K | 0.01% | 00.0% | Unchanged |
| Washington Trust Co | 734 | $332.8K | 0.01% | +6+0.8% | Added |
| Onefund, LLC | 734 | $332.8K | 0.20% | +39+5.6% | Added |
| DRW Securities, LLC | 746 | $334.5K | 0.03% | +746 | New |
| Haverford Trust Co | 740 | $335.5K | 0.00% | +740 | New |
| Boston Family Office LLC | 746 | $338.0K | 0.02% | 00.0% | Unchanged |
| FourThought Financial Partners, LLC | 748 | $339.1K | 0.03% | +18+2.5% | Added |
| Northstar Asset Management LLC | 750 | $340.0K | 0.07% | 00.0% | Unchanged |
| Baker Chad R | 750 | $340.3K | 0.06% | −8,990−92.3% | Reduced |
| Financial Symmetry Inc | 755 | $342.4K | 0.14% | 00.0% | Unchanged |
| Cura Wealth Advisors, LLC | 760 | $344.4K | 0.13% | +26+3.5% | Added |
| AlphaGrep UK Ltd | 760 | $344.6K | 0.12% | +760 | New |
| AlTi Global, Inc. | 762 | $345.5K | 0.01% | +762 | New |
| Clear Street Markets LLC | 763 | $345.9K | 0.06% | +679+808.3% | Added |
| Income Insurance Ltd | 764 | $346.4K | 0.22% | +764 | New |
| denkapparat Operations GmbH | 766 | $347.3K | 0.19% | 00.0% | Unchanged |
| One Charles Private Wealth Services, LLC | 767 | $347.7K | 0.09% | −60−7.3% | Reduced |
| Atalanta Sosnoff Capital, LLC | 773 | $350.2K | 0.01% | +2+0.3% | Added |
| Seven Mile Advisory | 778 | $352.6K | 0.06% | −4−0.5% | Reduced |
| Newman Dignan & Sheerar, Inc. | 779 | $353.2K | 0.07% | −37−4.5% | Reduced |
| Cercano Management LLC | 780 | $353.6K | 0.01% | 00.0% | Unchanged |
| Pinnacle Wealth Management Advisory Group, LLC | 780 | $353.6K | 0.02% | +15+2.0% | Added |
| Chesley Taft & Associates LLC | 782 | $354.5K | 0.01% | +219+38.9% | Added |
| Basecamp Wealth Advisors LLC | 789 | $357.7K | 0.08% | +789 | New |
| Arthur M. Cohen & Associates, LLC | 790 | $358.2K | 0.06% | −100−11.2% | Reduced |
| Integrity Alliance, LLC. | 790 | $358.2K | 0.01% | +790 | New |
| Montag A & Associates Inc | 797 | $361.3K | 0.02% | +587+279.5% | Added |
| Everpar Advisors LLC | 798 | $361.8K | 0.13% | +45+6.0% | Added |
| Arlington Capital Management, Inc. | 800 | $362.7K | 0.22% | +800 | New |
| VisionPoint Advisory Group, LLC | 802 | $363.6K | 0.07% | +802 | New |
| Sovran Advisors, LLC | 833 | $365.6K | 0.03% | −495−37.3% | Reduced |
| Meridian Wealth Management, LLC | 810 | $367.2K | 0.01% | +101+14.2% | Added |
| D.B. Root & Company, LLC | 813 | $368.6K | 0.09% | −144−15.0% | Reduced |
| PUREfi Wealth, LLC | 817 | $370.4K | 0.28% | −126−13.4% | Reduced |
| Bluedoor Private Wealth, LLC | 817 | $370.4K | 0.17% | +817 | New |
| FSM Wealth Advisors, LLC | 823 | $373.3K | 0.05% | +823 | New |
| New Republic Capital, LLC | 825 | $374.1K | 0.10% | +825 | New |
| RFG Advisory, LLC | 827 | $374.7K | 0.01% | +827 | New |
| Gallacher Capital Management LLC | 827 | $374.9K | 0.14% | −8−1.0% | Reduced |
| Trust Co of the South | 834 | $378.1K | 0.06% | +834 | New |
| Purpose Unlimited Inc. | 835 | $378.5K | 0.02% | +835 | New |
| Douglass Winthrop Advisors, LLC | 841 | $381.3K | 0.01% | −68−7.5% | Reduced |
| YHB Investment Advisors, Inc. | 841 | $381.3K | 0.03% | −52−5.8% | Reduced |
| AA Financial Advisors, LLC | 846 | $383.5K | 0.07% | +85+11.2% | Added |
| Foundations Investment Advisors, LLC | 847 | $383.9K | 0.01% | −17−2.0% | Reduced |
| Moss Adams Wealth Advisors LLC | 848 | $384.6K | 0.03% | +220+35.0% | Added |
| Freestone Capital Holdings, LLC | 849 | $384.9K | 0.01% | −63−6.9% | Reduced |
| Prestige Wealth Management Group LLC | 858 | $389.0K | 0.07% | +781+1,014.3% | Added |
| Marble Wealth, LLC | 865 | $392.0K | 0.05% | +865 | New |
| Essex Financial Services, Inc. | 866 | $392.6K | 0.02% | +48+5.9% | Added |
| Prescott Group Capital Management, L.L.C. | 869 | $394.0K | 0.04% | 00.0% | Unchanged |
| George Kaiser Family Foundation | 869 | $394.0K | 0.05% | 00.0% | Unchanged |
| Delta Financial Advisors LLC | 872 | $395.3K | 0.10% | +56+6.9% | Added |
| Soltis Investment Advisors LLC | 874 | $396.3K | 0.03% | +116+15.3% | Added |
| Independence Bank of Kentucky | 876 | $397.1K | 0.05% | +40+4.8% | Added |
| HBK Sorce Advisory LLC | 835 | $399.2K | 0.01% | +171+25.8% | Added |
| Ellevest, Inc. | 881 | $399.4K | 0.06% | −18−2.0% | Reduced |
| Forza Wealth Management, LLC | 881 | $399.4K | 0.14% | 00.0% | Unchanged |
| Guardian Asset Advisors, LLC | 885 | $401.2K | 0.21% | +10+1.1% | Added |
| Willner & Heller, LLC | 893 | $404.9K | 0.29% | −182−16.9% | Reduced |
| Aigen Investment Management, LP | 894 | $405.3K | 0.09% | +894 | New |
| E Fund Management (Hong Kong) Co., Ltd. | 860 | $405.9K | 0.17% | +616+252.5% | Added |
| Chicago Partners Investment Group LLC | 867 | $406.1K | 0.01% | −140−13.9% | Reduced |
| RiverFront Investment Group, LLC | 899 | $407.6K | 0.01% | −9−1.0% | Reduced |
| Ancora Advisors, LLC | 899 | $407.7K | 0.01% | +62+7.4% | Added |
| Fullerton Fund Management Co Ltd. | 900 | $408.0K | 0.02% | −622−40.9% | Reduced |
| Granite Bay Wealth Management, LLC | 902 | $408.9K | 0.10% | +2+0.2% | Added |
| Great Valley Advisor Group, Inc. | 907 | $411.2K | 0.01% | −118−11.5% | Reduced |
| Vantus Wealth LLC | 908 | $411.7K | 0.30% | +908 | New |
| First Citizens Bank & Trust Co | 910 | $412.6K | 0.01% | −730−44.5% | Reduced |
| Quotient Wealth Partners, LLC | 914 | $414.2K | 0.01% | −12−1.3% | Reduced |
| Elevated Private Wealth, LLC | 916 | $415.3K | 0.43% | +916 | New |
| Fulton Bank, N.A. | 927 | $420.3K | 0.01% | −97−9.5% | Reduced |
| Cabot Wealth Management Inc | 930 | $421.6K | 0.05% | −645−41.0% | Reduced |
| Congress Asset Management Co | 937 | $424.8K | 0.00% | −159,938−99.4% | Reduced |
| Ausdal Financial Partners, Inc. | 938 | $425.2K | 0.02% | −575−38.0% | Reduced |
| Richardson Financial Services Inc. | 952 | $431.6K | 0.27% | +10+1.1% | Added |
| Strategic Family Wealth Counselors, L.L.C. | 987 | $436.3K | 0.10% | +987 | New |
| Advyzon Investment Management, LLC | 966 | $437.9K | 0.05% | +966 | New |
| SK Wealth Management, LLC | 927 | $441.0K | 0.12% | 00.0% | Unchanged |
| Defined Wealth Management, LLC | 974 | $441.6K | 0.25% | +42+4.5% | Added |
| KCM Investment Advisors LLC | 976 | $442.5K | 0.01% | +976 | New |
| Clarius Group, LLC | 983 | $445.7K | 0.03% | −4−0.4% | Reduced |
| 17 Capital Partners, LLC | 990 | $448.8K | 0.23% | 00.0% | Unchanged |
| RMB Capital Management, LLC | 991 | $449.2K | 0.01% | −79−7.4% | Reduced |
| Alta Advisers Ltd | 991 | $449.3K | 0.16% | −280−22.0% | Reduced |
| Washington Growth Strategies LLC | 998 | $452.5K | 0.29% | 00.0% | Unchanged |
| Schwartz Investment Counsel Inc | 1,000 | $453.4K | 0.02% | 00.0% | Unchanged |
| Parkside Financial Bank & Trust | 1,002 | $454.3K | 0.03% | +308+44.4% | Added |
| Klingenstein Fields & Co LP | 1,005 | $455.6K | 0.02% | 00.0% | Unchanged |
| AGH Wealth Advisors, LLC | 1,006 | $456.1K | 0.34% | +71+7.6% | Added |
| TownSquare Capital, LLC | 1,007 | $456.5K | 0.10% | +152+17.8% | Added |
| GeoWealth Management, LLC | 1,010 | $458.1K | 0.02% | −8−0.8% | Reduced |
| Dynasty Wealth Management, LLC | 1,013 | $459.3K | 0.00% | +1,013 | New |