Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,671
- +174 vs. Q3 2025
- Shares held
- 241.6M
- +9.62M (+4.1%) vs. Q3 2025
- Total value
- $109.5B
- +$18.8B (+20.7%) vs. Q3 2025
- New holders
- 274
- 620 more added
- Sold out
- 100
- 566 more reduced
26 institutions that held it in Q3 2025 haven't filed for Q4 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Sterling Capital Management LLC | 17,542 | $7.95M | 0.13% | +64+0.4% | Added |
| Ossiam | 17,594 | $7.98M | 0.16% | +4,654+36.0% | Added |
| Nia Impact Advisors, LLC | 17,638 | $8.00M | 2.68% | +1,705+10.7% | Added |
| Mizuho Securities USA LLC | 18,474 | $8.01M | 0.13% | −200−1.1% | Reduced |
| Landscape Capital Management, L.L.C. | 18,054 | $8.18M | 0.55% | +7,570+72.2% | Added |
| QRG Capital Management, Inc. | 18,396 | $8.34M | 0.09% | +2,563+16.2% | Added |
| Generali Asset Management SPA SGR | 18,538 | $8.40M | 0.17% | −5,031−21.3% | Reduced |
| Pinnacle Financial Partners, Inc. | 18,588 | $8.43M | 0.06% | +18,588 | New |
| Azimuth Capital Investment Management LLC | 18,742 | $8.50M | 0.30% | −1,606−7.9% | Reduced |
| GW Henssler & Associates Ltd | 18,834 | $8.54M | 0.41% | −3,957−17.4% | Reduced |
| Abn Amro Investment Solutions | 19,070 | $8.65M | 0.13% | −106,890−84.9% | Reduced |
| Allstate Corp | 19,095 | $8.66M | 0.12% | +9,803+105.5% | Added |
| Mercer Global Advisors Inc | 23,822 | $8.99M | 0.01% | +5,038+26.8% | Added |
| UniSuper Management Pty Ltd | 19,992 | $9.06M | 0.05% | −503−2.5% | Reduced |
| Fiduciary Trust Co | 20,032 | $9.08M | 0.10% | −1,889−8.6% | Reduced |
| Heirloom Wealth Management | 20,199 | $9.16M | 2.12% | +233+1.2% | Added |
| AIMZ Investment Advisors, LLC | 20,261 | $9.19M | 2.63% | −100−0.5% | Reduced |
| Sig Brokerage, LP | 20,864 | $9.46M | 3.18% | −5,526−20.9% | Reduced |
| Capital Group Investment Management Pte. Ltd. | 20,865 | $9.46M | 1.54% | −5,421−20.6% | Reduced |
| Camden National Bank | 20,968 | $9.51M | 1.31% | +76+0.4% | Added |
| Grandfield & Dodd, LLC | 21,231 | $9.63M | 0.55% | +1,411+7.1% | Added |
| Modera Wealth Management, LLC | 21,275 | $9.65M | 0.11% | −578−2.6% | Reduced |
| Gotham Asset Management, LLC | 21,511 | $9.75M | 0.04% | −377−1.7% | Reduced |
| EULAV Asset Management | 22,000 | $9.97M | 0.27% | 00.0% | Unchanged |
| Wiley Bros.-Aintree Capital, LLC | 22,138 | $10.0M | 0.05% | −5,811−20.8% | Reduced |
| Fifth Third Bancorp | 22,158 | $10.0M | 0.03% | −65−0.3% | Reduced |
| Acadian Asset Management LLC | 22,210 | $10.1M | 0.02% | +21,953+8,542.0% | Added |
| Investment Management Corp of Ontario | 22,300 | $10.1M | 0.13% | +7,065+46.4% | Added |
| Cary Street Partners Financial LLC | 22,355 | $10.1M | 0.25% | −568−2.5% | Reduced |
| Telos Capital Management, Inc. | 22,376 | $10.1M | 0.95% | +1,188+5.6% | Added |
| Exencial Wealth Advisors, LLC | 22,382 | $10.1M | 0.32% | +20,882+1,392.1% | Added |
| Kennedy Capital Management, Inc. | 22,414 | $10.2M | 0.22% | +234+1.1% | Added |
| Ieq Capital, LLC | 22,524 | $10.2M | 0.03% | +16,073+249.2% | Added |
| Warren Averett Asset Management, LLC | 22,732 | $10.3M | 0.08% | +2,484+12.3% | Added |
| HealthInvest Partners AB | 22,984 | $10.4M | 3.32% | +5,218+29.4% | Added |
| Somerville Kurt F | 23,327 | $10.6M | 1.79% | +684+3.0% | Added |
| Motley Fool Asset Management LLC | 23,603 | $10.7M | 0.42% | +5,905+33.4% | Added |
| Yousif Capital Management, LLC | 24,304 | $10.7M | 0.12% | −1,358−5.3% | Reduced |
| Capital Group Private Client Services, Inc. | 23,852 | $10.8M | 0.17% | −1,022−4.1% | Reduced |
| Eurizon SLJ Capital Ltd | 24,156 | $11.0M | 4.34% | +24,156 | New |
| Norinchukin Bank, The | 24,203 | $11.0M | 0.13% | +2,177+9.9% | Added |
| Banque Pictet & Cie SA | 24,328 | $11.0M | 0.11% | +15,470+174.6% | Added |
| Advisors Asset Management, Inc. | 24,713 | $11.2M | 0.19% | −1,213−4.7% | Reduced |
| Jain Global LLC | 24,978 | $11.3M | 0.11% | +24,978 | New |
| Biondo Investment Advisors, LLC | 25,140 | $11.4M | 1.38% | +65+0.3% | Added |
| Allianz SE | 25,181 | $11.4M | 0.15% | +1,260+5.3% | Added |
| Fisher Asset Management, LLC | 25,218 | $11.4M | 0.00% | −741−2.9% | Reduced |
| Pinnacle Associates Ltd | 25,238 | $11.4M | 0.15% | −129−0.5% | Reduced |
| Meritage Portfolio Management | 25,438 | $11.5M | 0.77% | −502−1.9% | Reduced |
| LVM Capital Management Ltd | 25,775 | $11.7M | 1.09% | −65−0.3% | Reduced |
| ASR Vermogensbeheer N.V. | 26,059 | $11.8M | 0.14% | −235−0.9% | Reduced |
| ARK Investment Management LLCSuperinvestorARK Invest | 26,100 | $11.8M | 0.08% | +435+1.7% | Added |
| CCM Investment Advisers LLC | 26,249 | $11.9M | 1.14% | −2,060−7.3% | Reduced |
| Generate Investment Management Ltd | 26,334 | $11.9M | 0.54% | +600+2.3% | Added |
| Bender Robert & Associates | 26,463 | $12.0M | 2.49% | +133+0.5% | Added |
| Fagan Associates, Inc. | 26,566 | $12.0M | 1.61% | +260+1.0% | Added |
| Americana Partners, LLC | 27,133 | $12.3M | 0.34% | +2,665+10.9% | Added |
| Bogart Wealth, LLC | 27,177 | $12.3M | 0.49% | +1,028+3.9% | Added |
| Mutual of America Capital Management LLC | 27,197 | $12.3M | 0.13% | −549−2.0% | Reduced |
| Bridgewater Associates, LP | 27,488 | $12.5M | 0.05% | −10,836−28.3% | Reduced |
| Avanza Fonder AB | 27,585 | $12.5M | 0.32% | +532+2.0% | Added |
| Shelter Mutual Insurance Co | 27,600 | $12.5M | 2.79% | 00.0% | Unchanged |
| Massmutual Trust Co FSB | 27,914 | $12.7M | 0.33% | −581−2.0% | Reduced |
| Atria Investments LLC | 28,261 | $12.8M | 0.15% | +2,342+9.0% | Added |
| OP Asset Management Ltd | 28,452 | $12.9M | 0.16% | +164+0.6% | Added |
| Intech Investment Management LLC | 28,530 | $12.9M | 0.12% | −5,831−17.0% | Reduced |
| Profund Advisors LLC | 28,818 | $13.1M | 0.40% | +2,423+9.2% | Added |
| CAPROCK Group, Inc. | 29,023 | $13.2M | 0.28% | +3,807+15.1% | Added |
| Oregon Public Employees Retirement Fund | 29,044 | $13.2M | 0.17% | −241−0.8% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 29,189 | $13.2M | 0.20% | +2,405+9.0% | Added |
| Apollon Wealth Management, LLC | 29,195 | $13.2M | 0.23% | −171−0.6% | Reduced |
| Washington Trust Bank | 29,839 | $13.5M | 0.95% | +30+0.1% | Added |
| US Bancorp | 29,850 | $13.5M | 0.02% | −1,006−3.3% | Reduced |
| Louisiana State Employees Retirement System | 30,000 | $13.6M | 0.23% | −2,200−6.8% | Reduced |
| Barlow Wealth Partners, Inc. | 30,087 | $14.0M | 1.51% | +207+0.7% | Added |
| Fideuram - Intesa Sanpaolo Private Banking S.P.A. | 31,281 | $14.2M | 0.51% | +31,281 | New |
| Jefferies Financial Group Inc. | 31,372 | $14.2M | 0.12% | +15,372+96.1% | Added |
| Elo Mutual Pension Insurance Co | 31,613 | $14.3M | 0.22% | −2,170−6.4% | Reduced |
| Foster Victor Wealth Advisors, LLC | 32,929 | $14.5M | 0.85% | −928−2.7% | Reduced |
| Public Sector Pension Investment Board | 32,851 | $14.9M | 0.05% | +10,433+46.5% | Added |
| State of Alaska, Department of Revenue | 32,915 | $14.9M | 0.16% | −2,938−8.2% | Reduced |
| Huntington National Bank | 32,999 | $15.0M | 0.09% | +3,552+12.1% | Added |
| AIA Group Ltd | 33,821 | $15.3M | 0.23% | −22,233−39.7% | Reduced |
| Bailard, Inc. | 33,975 | $15.4M | 0.34% | −664−1.9% | Reduced |
| Rhenman & Partners Asset Management AB | 34,255 | $15.5M | 1.45% | −12,700−27.0% | Reduced |
| Galvin, Gaustad & Stein, LLC | 34,309 | $15.6M | 1.21% | +1,167+3.5% | Added |
| Sapient Capital LLC | 34,324 | $15.6M | 0.22% | +130.0% | Added |
| McRae Capital Management Inc | 35,558 | $16.1M | 3.29% | +2,399+7.2% | Added |
| Andra AP-fonden | 35,940 | $16.3M | 0.20% | +40+0.1% | Added |
| Allianz Asset Management GmbH | 36,276 | $16.4M | 0.02% | −73,885−67.1% | Reduced |
| Vestcor Inc | 36,690 | $16.6M | 0.47% | +1,424+4.0% | Added |
| Flputnam Investment Management Co | 36,791 | $16.7M | 0.24% | +2,115+6.1% | Added |
| New York Life Investment Management LLC | 36,818 | $16.7M | 0.14% | −614−1.6% | Reduced |
| Virginia Retirement Systems Et Al | 37,100 | $16.8M | 0.10% | 00.0% | Unchanged |
| Shelton Capital Management | 37,241 | $16.9M | 0.33% | +562+1.5% | Added |
| iA Global Asset Management Inc. | 37,685 | $17.1M | 0.22% | +1,843+5.1% | Added |
| MML Investors Services, LLC | 38,004 | $17.2M | 0.04% | +3,773+11.0% | Added |
| Aristotle Atlantic Partners, LLC | 38,391 | $17.4M | 0.80% | −1,413−3.5% | Reduced |
| Ilmarinen Mutual Pension Insurance Co | 38,800 | $17.6M | 0.14% | 00.0% | Unchanged |
| Tweedy, Browne Co LLC | 39,148 | $17.7M | 1.43% | +83+0.2% | Added |