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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,523
−12 vs. Q2 2025
Shares held
232.3M
−4.81M (−2.0%) vs. Q2 2025
Total value
$90.8B
−$14.7B (−14.0%) vs. Q2 2025
New holders
143
553 more added
Sold out
155
617 more reduced

28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 1,523 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ3 2025: $90.8B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.

Institutions holding VRTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Advisory Resource Group3,284$1.29M0.23%+3,284New
SageView Advisory Group, LLC3,297$1.29M0.04%−548−14.3%Reduced
Mattern Capital Management, LLC3,312$1.30M0.15%+980+42.0%Added
Sculati Wealth Management, LLC3,328$1.30M0.46%+149+4.7%Added
Pure Financial Advisors, Inc.3,330$1.30M0.02%+439+15.2%Added
Catalytic Wealth RIA, LLC3,332$1.30M0.04%+1,567+88.8%Added
D. E. Shaw & Co., Inc.3,343$1.31M0.00%−16,738−83.4%Reduced
Procyon Private Wealth Partners, LLC3,345$1.31M0.08%−1,083−24.5%Reduced
Berkshire Asset Management LLC3,370$1.32M0.06%00.0%Unchanged
Farther Finance Advisors, LLC3,393$1.33M0.02%+487+16.8%Added
Panagora Asset Management Inc3,408$1.33M0.01%00.0%Unchanged
Triglav Skladi, D.O.O.3,450$1.35M0.09%00.0%Unchanged
NorthRock Partners, LLC3,452$1.35M0.02%+276+8.7%Added
Wedmont Private Capital3,299$1.35M0.05%−1,985−37.6%Reduced
CWA Asset Management Group, LLC3,469$1.36M0.05%−2,805−44.7%Reduced
Ifrah Financial Services, Inc.3,476$1.36M0.35%−25−0.7%Reduced
Tealwood Asset Management Inc3,483$1.36M0.55%+17+0.5%Added
Midwest Professional Planners, LTD.3,496$1.37M0.33%+71+2.1%Added
Clearstead Advisors, LLC3,527$1.38M0.02%+7+0.2%Added
1858 Wealth Management, LLC3,542$1.39M0.97%+1,079+43.8%Added
Nilsine Partners, LLC3,552$1.39M0.13%−173−4.6%Reduced
Grange Capital, LLC3,554$1.39M1.35%+3,554New
Stephens Inc3,564$1.40M0.02%+172+5.1%Added
DSG Capital Advisors, LLC3,565$1.40M0.22%+20+0.6%Added
Icon Wealth Advisors, LLC3,567$1.40M0.09%+982+38.0%Added
Moors & Cabot, Inc.3,579$1.40M0.06%−555−13.4%Reduced
Oppenheimer & Co Inc3,604$1.41M0.02%−237−6.2%Reduced
Sound View Wealth Advisors Group, LLC3,629$1.42M0.10%+5+0.1%Added
Moody National Bank Trust Division3,649$1.43M0.12%+208+6.0%Added
MBM Wealth Consultants, LLC3,650$1.43M0.35%+775+27.0%Added
Ritholtz Wealth Management3,653$1.43M0.03%−9−0.2%Reduced
Richard Bernstein Advisors LLC3,692$1.45M0.04%−4,059−52.4%Reduced
Andrew Hill Investment Advisors, Inc.3,709$1.45M1.13%−4,294−53.7%Reduced
Roberts Glore & Co Inc3,715$1.45M0.40%+93+2.6%Added
National Asset Management, Inc.3,725$1.46M0.07%−416−10.0%Reduced
Quantbot Technologies LP3,727$1.46M0.04%+3,727New
Lighthouse Financial LLC3,730$1.46M0.96%00.0%Unchanged
Portside Wealth Group, LLC3,743$1.47M0.20%+545+17.0%Added
Dynamic Advisor Solutions LLC3,778$1.48M0.04%+839+28.5%Added
ZWJ Investment Counsel Inc3,791$1.48M0.05%+14+0.4%Added
J. Safra Sarasin Holding AG3,827$1.50M0.02%+827+27.6%Added
Snowden Capital Advisors LLC3,831$1.50M0.04%−126−3.2%Reduced
Phoenix Holdings Ltd.3,841$1.50M0.02%+1,401+57.4%Added
Avestar Capital, LLC3,872$1.52M0.11%−239−5.8%Reduced
Aaron Wealth Advisors3,922$1.54M0.09%+703+21.8%Added
ICICI Prudential Asset Management Co Ltd3,937$1.54M0.16%+719+22.3%Added
Alaethes Wealth LLC3,954$1.55M0.44%+745+23.2%Added
Mission Wealth Management, LP3,967$1.55M0.03%−1,742−30.5%Reduced
JT Stratford LLC3,975$1.56M0.21%+161+4.2%Added
STF Management LP3,986$1.56M0.58%−109−2.7%Reduced
Choate Investment Advisors3,991$1.56M0.03%−311−7.2%Reduced
Woodstock Corp4,005$1.57M0.14%00.0%Unchanged
Sowell Financial Services LLC4,012$1.57M0.06%+1,215+43.4%Added
Clal Insurance Enterprises Holdings Ltd4,026$1.58M0.01%+1,506+59.8%Added
Mattson Financial Services, LLC4,046$1.58M0.38%+143+3.7%Added
Philip James Wealth Mangement, LLC4,059$1.59M0.19%−399−9.0%Reduced
MRP Capital Investments, LLC3,575$1.59M1.37%−900−20.1%Reduced
Texas Yale Capital Corp.4,088$1.60M0.05%+120+3.0%Added
Canada Post Corp Registered Pension Plan4,054$1.60M0.07%+200+5.2%Added
S&CO Inc4,103$1.61M0.10%00.0%Unchanged
Signature Wealth Management Group4,111$1.61M0.62%−133−3.1%Reduced
Mutual Advisors, LLC3,822$1.62M0.04%+547+16.7%Added
Cambria Investment Management, L.P.4,181$1.64M0.10%+271+6.9%Added
GKV Capital Management Co., Inc.4,205$1.65M0.65%+177+4.4%Added
Vise Technologies, Inc.4,223$1.65M0.06%−55−1.3%Reduced
Belpointe Asset Management LLC4,235$1.66M0.06%+455+12.0%Added
Lipe & Dalton4,246$1.66M0.82%−60−1.4%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP3,950$1.67M0.01%+3,206+430.9%Added
Everence Capital Management Inc4,274$1.67M0.10%−790−15.6%Reduced
Nations Financial Group Inc,4,290$1.68M0.10%+74+1.8%Added
Waldron Private Wealth LLC4,300$1.68M0.07%+119+2.8%Added
Mather Group, LLC.4,339$1.70M0.02%+23+0.5%Added
111 Capital4,363$1.71M0.32%+4,363New
Harrell Investment Partners, LLC4,365$1.71M0.40%+13+0.3%Added
Alpine Woods Capital Investors, LLC4,421$1.73M0.40%−1,173−21.0%Reduced
3Chopt Investment Partners, LLC4,433$1.74M0.40%−479−9.8%Reduced
Private Harbour Investment Management & Counsel, LLC4,449$1.74M1.80%−331−6.9%Reduced
McGuire Investment Group, LLC4,453$1.74M0.20%−661−12.9%Reduced
HighPoint Advisor Group LLC4,504$1.76M0.08%+467+11.6%Added
SFMG, LLC4,555$1.78M0.12%−78−1.7%Reduced
Integrated Wealth Concepts LLC4,574$1.79M0.02%+244+5.6%Added
Impax Asset Management Group plc4,622$1.81M0.01%00.0%Unchanged
GAMMA Investing LLC4,632$1.81M0.10%−80−1.7%Reduced
Westerkirk Capital Inc.4,642$1.82M0.21%+1,842+65.8%Added
Decatur Capital Management, Inc.4,664$1.83M0.73%+26+0.6%Added
Brighton Jones LLC4,693$1.84M0.04%+134+2.9%Added
Greenleaf Trust4,703$1.84M0.02%−334−6.6%Reduced
Oarsman Capital, Inc.4,716$1.85M0.26%+329+7.5%Added
Valeo Financial Advisors, LLC4,756$1.86M0.04%+185+4.0%Added
Glenmede Investment Management, LP4,768$1.87M0.01%+96+2.1%Added
LGT Group Foundation4,620$1.87M0.02%+1,881+68.7%Added
GLOBALT Investments LLC4,772$1.87M0.07%−2,513−34.5%Reduced
Oak Associates, Ltd4,771$1.87M0.11%00.0%Unchanged
Trustmark National Bank Trust Department4,831$1.89M0.12%−109−2.2%Reduced
Advisory Services Network, LLC4,847$1.90M0.03%−1,275−20.8%Reduced
Bangor Savings Bank4,899$1.92M0.16%−30−0.6%Reduced
MUFG Securities EMEA plc4,907$1.92M0.05%+4,150+548.2%Added
Hilltop Holdings Inc.4,934$1.93M0.10%+757+18.1%Added
TFR Capital, LLC.4,935$1.93M0.65%−15−0.3%Reduced
Summit Global Investments4,974$1.95M0.11%+1,062+27.1%Added