Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,763 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,564 | $107.2B |
| Q1 2025 | 1,618 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,288 | $83.3B |
| Q1 2023 | 1,213 | $75.0B |
| Q4 2022 | 1,225 | $68.3B |
| Q3 2022 | 1,128 | $68.5B |
| Q2 2022 | 1,110 | $66.1B |
| Q1 2022 | 1,073 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Global Assets Advisory, LLC | 1,564 | $612.5K | 0.18% | +80+5.4% | Added |
| LOM Asset Management Ltd | 1,565 | $613.0K | 0.19% | 00.0% | Unchanged |
| Sava Infond d.o.o. | 1,570 | $614.9K | 0.09% | 00.0% | Unchanged |
| Whittier Trust Co | 1,526 | $615.4K | 0.01% | −294−16.2% | Reduced |
| KRS Capital Management, LLC | 1,572 | $615.7K | 0.37% | −50−3.1% | Reduced |
| Cabot Wealth Management Inc | 1,575 | $616.8K | 0.07% | +1,575 | New |
| First Manhattan Co | 1,580 | $618.8K | 0.00% | −5−0.3% | Reduced |
| Fukoku Mutual Life Insurance Co | 1,589 | $622.3K | 0.04% | 00.0% | Unchanged |
| Flagship Harbor Advisors, LLC | 1,590 | $622.7K | 0.03% | −30−1.9% | Reduced |
| Alta Wealth Advisors LLC | 1,596 | $625.1K | 0.22% | −196−10.9% | Reduced |
| Simplex Trading, LLC | 1,603 | $627.0K | 0.01% | +1,603 | New |
| Perfromance Wealth Partners, LLC | 1,605 | $628.6K | 0.02% | +5+0.3% | Added |
| Peapack Gladstone Financial Corp | 1,611 | $630.0K | 0.01% | +15+0.9% | Added |
| Sigma Planning Corp | 1,632 | $639.1K | 0.02% | −648−28.4% | Reduced |
| Oxler Private Wealth LLC | 1,632 | $639.2K | 0.19% | −42−2.5% | Reduced |
| Campbell Newman Asset Management Inc | 1,634 | $639.9K | 0.05% | +8+0.5% | Added |
| SRS Capital Advisors, Inc. | 1,639 | $642.2K | 0.01% | +616+60.2% | Added |
| First Citizens Bank & Trust Co | 1,640 | $642.3K | 0.01% | +37+2.3% | Added |
| Destination Wealth Management | 1,642 | $643.1K | 0.02% | +89+5.7% | Added |
| Summit Financial, LLC | 1,643 | $643.5K | 0.01% | −230−12.3% | Reduced |
| Vista Investment Management | 1,648 | $645.4K | 0.23% | +34+2.1% | Added |
| Strategic Investment Advisors | 1,650 | $646.2K | 0.06% | −124−7.0% | Reduced |
| Reuter James Wealth Management, LLC | 1,659 | $649.7K | 0.09% | +280+20.3% | Added |
| Quantitative Investment Management, LLC | 1,672 | $654.0K | 0.09% | +1,672 | New |
| Empirical Financial Services, LLC d.b.a. Empirical Wealth Management | 1,675 | $656.0K | 0.01% | −377−18.4% | Reduced |
| R Squared Ltd | 1,680 | $658.0K | 0.28% | +1,680 | New |
| Mount Yale Investment Advisors, LLC | 1,685 | $659.9K | 0.05% | +1,352+406.0% | Added |
| Premier Path Wealth Partners, LLC | 1,690 | $662.0K | 0.09% | −145−7.9% | Reduced |
| Roman Butler Fullerton & Co | 1,594 | $664.9K | 0.18% | −1,983−55.4% | Reduced |
| Raab & Moskowitz Asset Management LLC | 1,701 | $666.2K | 0.15% | 00.0% | Unchanged |
| Claro Advisors LLC | 1,718 | $672.8K | 0.10% | −828−32.5% | Reduced |
| Perbak Capital Partners LLP | 1,727 | $676.4K | 0.12% | +1,727 | New |
| Triangle Securities Wealth Management | 1,736 | $679.9K | 0.15% | +8+0.5% | Added |
| Bradley Foster & Sargent Inc | 1,743 | $682.6K | 0.01% | −228−11.6% | Reduced |
| Guidance Capital, Inc | 1,630 | $686.9K | 0.18% | −313−16.1% | Reduced |
| Altfest L J & Co Inc | 1,757 | $688.1K | 0.08% | −9−0.5% | Reduced |
| Prosperity Wealth Management, Inc. | 1,757 | $688.1K | 0.23% | +1,757 | New |
| Strategic Blueprint, LLC | 1,764 | $690.9K | 0.03% | −43−2.4% | Reduced |
| Souders Financial Advisors | 1,764 | $690.9K | 0.08% | +455+34.8% | Added |
| Kane Investment Management, Inc. | 1,768 | $692.4K | 0.34% | −463−20.8% | Reduced |
| AE Wealth Management LLC | 1,772 | $694.2K | 0.00% | −696−28.2% | Reduced |
| Great Lakes Retirement, Inc. | 1,789 | $700.6K | 0.08% | +65+3.8% | Added |
| TD Private Client Wealth LLC | 1,791 | $701.4K | 0.02% | −2,327−56.5% | Reduced |
| Csenge Advisory Group | 1,792 | $701.8K | 0.03% | −304−14.5% | Reduced |
| Generali Investments, Management Co LLC | 1,797 | $703.8K | 0.15% | +1,797 | New |
| Fifth Third Wealth Advisors LLC | 1,800 | $705.0K | 0.03% | −26−1.4% | Reduced |
| CX Institutional | 1,806 | $707.0K | 0.02% | +52+3.0% | Added |
| Acima Private Wealth, LLC | 1,806 | $707.3K | 0.22% | 00.0% | Unchanged |
| Appleton Partners Inc | 1,808 | $708.0K | 0.05% | 00.0% | Unchanged |
| Oak Ridge Investments LLC | 1,814 | $710.4K | 0.05% | −2−0.1% | Reduced |
| Aureus Asset Management, LLC | 1,818 | $712.0K | 0.05% | 00.0% | Unchanged |
| Umb Bank N A | 1,838 | $719.8K | 0.01% | −465−20.2% | Reduced |
| MAI Capital Management | 1,846 | $722.8K | 0.00% | −281−13.2% | Reduced |
| Goelzer Investment Management, Inc. | 1,866 | $730.8K | 0.04% | −33−1.7% | Reduced |
| Hobbs Group Advisors, LLC | 1,871 | $732.9K | 0.23% | −737−28.3% | Reduced |
| Qtron Investments LLC | 1,874 | $733.9K | 0.09% | −142−7.0% | Reduced |
| Rehmann Capital Advisory Group | 1,876 | $735.5K | 0.04% | +168+9.8% | Added |
| Livforsakringsbolaget Skandia, Omsesidigt | 1,880 | $736.1K | 0.03% | 00.0% | Unchanged |
| Badgley Phelps Wealth Managers, LLC | 1,887 | $739.0K | 0.02% | 00.0% | Unchanged |
| Adviser Investments LLC | 1,890 | $740.2K | 0.01% | −453−19.3% | Reduced |
| Twin Capital Management Inc | 1,905 | $746.1K | 0.09% | +1,905 | New |
| Gryphon Financial Partners LLC | 1,907 | $746.9K | 0.09% | +784+69.8% | Added |
| Howland Capital Management LLC | 1,918 | $751.2K | 0.03% | +142+8.0% | Added |
| Advisory Alpha, LLC | 1,852 | $757.2K | 0.02% | +151+8.9% | Added |
| IFG Advisory, LLC | 1,941 | $760.2K | 0.03% | −44−2.2% | Reduced |
| Baker Ellis Asset Management LLC | 1,952 | $764.5K | 0.09% | +900+85.6% | Added |
| Spears Abacus Advisors LLC | 1,960 | $767.6K | 0.01% | +88+4.7% | Added |
| Breakwater Capital Group | 1,961 | $768.0K | 0.11% | +122+6.6% | Added |
| Stonegate Investment Group, LLC | 1,963 | $768.8K | 0.02% | −4,179−68.0% | Reduced |
| Annis Gardner Whiting Capital Advisors, LLC | 1,967 | $770.4K | 0.16% | +6+0.3% | Added |
| Mystic Asset Management, Inc. | 2,000 | $783.3K | 0.18% | 00.0% | Unchanged |
| Fort Sheridan Advisors LLC | 2,002 | $784.1K | 0.10% | −74−3.6% | Reduced |
| Sage Mountain Advisors LLC | 2,008 | $786.3K | 0.05% | +603+42.9% | Added |
| Allegheny Financial Group LTD | 2,009 | $786.8K | 0.15% | +9+0.4% | Added |
| Dark Forest Capital Management LP | 2,010 | $787.2K | 0.03% | +2,010 | New |
| Simplicity Wealth,LLC | 2,013 | $788.4K | 0.05% | −1,022−33.7% | Reduced |
| Fidelis Capital Partners, LLC | 2,019 | $790.7K | 0.06% | −3,336−62.3% | Reduced |
| Campbell & CO Investment Adviser LLC | 2,023 | $792.3K | 0.06% | +2,023 | New |
| Cito Capital Group, LLC | 2,056 | $805.0K | 0.23% | +2,056 | New |
| Harel Insurance Investments & Financial Services Ltd. | 2,057 | $806.0K | 0.01% | +787+62.0% | Added |
| Schmidt P J Investment Management Inc | 2,068 | $809.9K | 0.13% | −14−0.7% | Reduced |
| Fortis Capital Advisors, LLC | 2,077 | $813.4K | 0.13% | +342+19.7% | Added |
| Polymer Capital Management (US) LLC | 2,082 | $815.4K | 0.11% | +2,082 | New |
| Ipswich Investment Management Co., Inc. | 2,083 | $815.8K | 0.19% | −3,525−62.9% | Reduced |
| Everhart Financial Group, Inc. | 2,088 | $817.7K | 0.08% | +207+11.0% | Added |
| Formidable Asset Management, LLC | 1,987 | $820.0K | 0.13% | −32−1.6% | Reduced |
| Generali Investments Towarzystwo Funduszy Inwestycyjnych | 2,100 | $822.4K | 0.44% | +900+75.0% | Added |
| Evercore Wealth Management, LLC | 2,106 | $824.8K | 0.01% | −22−1.0% | Reduced |
| PFG Investments, LLC | 2,118 | $829.5K | 0.04% | +246+13.1% | Added |
| Cherry Creek Investment Advisors, Inc. | 2,122 | $831.1K | 0.36% | −986−31.7% | Reduced |
| Presilium Private Wealth, LLC | 2,124 | $831.8K | 0.16% | 00.0% | Unchanged |
| HM Payson & Co | 2,133 | $835.3K | 0.01% | −65−3.0% | Reduced |
| Pflug Koory, LLC | 2,137 | $836.9K | 0.40% | +91+4.4% | Added |
| Mitchell & Pahl Private Wealth, LLC | 2,144 | $839.7K | 0.35% | 00.0% | Unchanged |
| We Are One Seven, LLC | 2,150 | $842.0K | 0.02% | +328+18.0% | Added |
| Impact Capital Partners LLC | 2,151 | $842.4K | 0.25% | +12+0.6% | Added |
| Argent Trust Co | 2,183 | $854.9K | 0.03% | −215−9.0% | Reduced |
| AdvisorNet Financial, Inc | 2,199 | $861.2K | 0.05% | +525+31.4% | Added |
| Montis Financial, LLC | 2,199 | $861.2K | 0.20% | +2,199 | New |
| Mitsubishi UFJ Asset Management (UK) Ltd. | 2,200 | $862.0K | 0.42% | +2,200 | New |