Skip to main content

Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,523
−13 vs. Q2 2025
Shares held
232.3M
−4.81M (−2.0%) vs. Q2 2025
Total value
$90.8B
−$14.7B (−14.0%) vs. Q2 2025
New holders
143
553 more added
Sold out
156
617 more reduced

28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 1,523 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ3 2025: $90.8B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.

Institutions holding VRTX in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Massachusetts Wealth Management722$282.8K0.14%+162+28.9%Added
Washington Trust Co728$285.1K0.01%+728New
Castleark Management LLC730$285.9K0.01%00.0%Unchanged
FourThought Financial Partners, LLC730$285.9K0.03%+19+2.7%Added
Nicholas Hoffman & Company, LLC.732$286.7K0.01%00.0%Unchanged
Cura Wealth Advisors, LLC734$287.5K0.11%+159+27.7%Added
Alpha Zero LLC735$287.9K0.17%+74+11.2%Added
United Advisor Group, LLC738$289.0K0.04%+144+24.2%Added
McAdam, LLC740$289.8K0.01%+140+23.3%Added
Fairfield Financial Advisors, LTD743$291.0K0.10%+743New
Kestra Investment Management, LLC745$291.8K0.01%−390−34.4%Reduced
Boston Family Office LLC746$292.0K0.02%−50−6.3%Reduced
Kraematon Investment Advisors, Inc748$292.8K0.25%−203−21.3%Reduced
Northstar Asset Management LLC750$293.7K0.06%00.0%Unchanged
Everpar Advisors LLC753$294.9K0.12%−39−4.9%Reduced
Financial Symmetry Inc755$295.8K0.13%00.0%Unchanged
Soltis Investment Advisors LLC758$296.8K0.02%−38−4.8%Reduced
AA Financial Advisors, LLC761$298.0K0.06%+129+20.4%Added
Optas, LLC764$299.2K0.05%−143−15.8%Reduced
Pinnacle Wealth Management Advisory Group, LLC765$299.6K0.02%+8+1.1%Added
denkapparat Operations GmbH766$300.0K0.19%00.0%Unchanged
GK Wealth Management LLC767$300.4K0.22%+78+11.3%Added
Requisite Capital Management, LLC768$300.8K0.05%+768New
Capula Management Ltd770$301.6K0.00%+667+647.6%Added
Atalanta Sosnoff Capital, LLC771$302.1K0.01%−30,985−97.6%Reduced
Davis R M Inc775$303.4K0.01%−360−31.7%Reduced
Cercano Management LLC780$305.5K0.01%00.0%Unchanged
Seven Mile Advisory782$306.2K0.05%+70+9.8%Added
Interchange Capital Partners, LLC784$307.0K0.06%−268−25.5%Reduced
Stock Yards Bank & Trust Co789$309.0K0.01%−20−2.5%Reduced
Mitchell McLeod Pugh & Williams Inc737$311.3K0.05%−5−0.7%Reduced
Delta Financial Advisors LLC816$319.6K0.09%+28+3.6%Added
Newman Dignan & Sheerar, Inc.816$319.6K0.07%+30+3.8%Added
Essex Financial Services, Inc.818$320.4K0.02%+46+6.0%Added
One Charles Private Wealth Services, LLC827$323.9K0.09%+123+17.5%Added
Gallacher Capital Management LLC835$327.0K0.13%+835New
Independence Bank of Kentucky836$327.4K0.04%+260+45.1%Added
Ancora Advisors, LLC837$327.9K0.01%+1+0.1%Added
TRUE Private Wealth Advisors840$329.3K0.03%−105−11.1%Reduced
Davy Global Fund Management Ltd852$333.7K0.02%+307+56.3%Added
DGS Capital Management, LLC854$334.5K0.06%+350+69.4%Added
TownSquare Capital, LLC855$334.9K0.05%−1,612−65.3%Reduced
Larson Financial Group LLC863$338.0K0.01%+52+6.4%Added
Lockerman Financial Group, Inc.863$338.0K0.43%00.0%Unchanged
Foundations Investment Advisors, LLC864$338.3K0.00%−138−13.8%Reduced
Prescott Group Capital Management, L.L.C.869$340.3K0.04%00.0%Unchanged
George Kaiser Family Foundation869$340.3K0.05%00.0%Unchanged
David Loasby835$342.6K0.03%−250−23.0%Reduced
Guardian Asset Advisors, LLC875$342.7K0.18%−92−9.5%Reduced
Forza Wealth Management, LLC881$345.0K0.13%00.0%Unchanged
Portfolio Design Labs, LLC889$348.2K0.06%+9+1.0%Added
Arthur M. Cohen & Associates, LLC890$348.6K0.06%00.0%Unchanged
YHB Investment Advisors, Inc.893$349.7K0.03%+2+0.2%Added
GPS Wealth Strategies Group, LLC896$350.9K0.04%−163−15.4%Reduced
Ellevest, Inc.899$352.1K0.05%+22+2.5%Added
Granite Bay Wealth Management, LLC900$352.5K0.09%00.0%Unchanged
Cozad Asset Management Inc900$352.5K0.03%00.0%Unchanged
Bridgefront Capital, LLC903$353.7K0.10%+903New
RiverFront Investment Group, LLC908$355.6K0.01%−79−8.0%Reduced
Douglass Winthrop Advisors, LLC909$356.0K0.01%+41+4.7%Added
Freestone Capital Holdings, LLC912$357.2K0.01%+912New
Cynosure Management, LLC918$359.5K0.04%00.0%Unchanged
Quotient Wealth Partners, LLC926$362.6K0.01%−145−13.5%Reduced
EverSource Wealth Advisors, LLC932$364.8K0.01%−14−1.5%Reduced
Defined Wealth Management, LLC932$365.0K0.21%+27+3.0%Added
AGH Wealth Advisors, LLC935$366.2K0.27%+399+74.4%Added
Richardson Financial Services Inc.942$368.9K0.23%−78−7.6%Reduced
PUREfi Wealth, LLC943$369.3K0.28%+7+0.7%Added
HMS Capital Management, LLC945$370.1K0.16%−3−0.3%Reduced
Natural Investments, LLC948$371.0K0.09%−68−6.7%Reduced
Journey Strategic Wealth LLC954$373.6K0.01%−649−40.5%Reduced
D.B. Root & Company, LLC957$374.8K0.10%−125−11.6%Reduced
Venture Visionary Partners LLC957$374.8K0.01%+263+37.9%Added
Virtus Investment Advisers, Inc.966$378.3K0.11%00.0%Unchanged
Ramiah Investment Group970$379.9K0.34%+77+8.6%Added
LVW Advisors, LLC971$380.3K0.04%+158+19.4%Added
SK Wealth Management, LLC927$384.6K0.14%00.0%Unchanged
Clarius Group, LLC987$386.5K0.02%−638−39.3%Reduced
17 Capital Partners, LLC990$387.7K0.21%−30−2.9%Reduced
BridgePort Financial Solutions, LLC991$388.1K0.10%+148+17.6%Added
Washington Growth Strategies LLC998$390.9K0.28%00.0%Unchanged
One Wealth Capital Management, LLC998$390.9K0.18%+195+24.3%Added
Schwartz Investment Counsel Inc1,000$391.6K0.01%00.0%Unchanged
NJ State Employees Deferred Compensation Plan1,000$391.6K0.04%00.0%Unchanged
Consolidated Portfolio Review Corp1,002$392.4K0.05%+1,002New
Angeles Wealth Management, LLC1,004$393.2K0.02%−280−21.8%Reduced
Klingenstein Fields & Co LP1,005$393.6K0.01%00.0%Unchanged
Capital Investment Advisors, LLC1,009$395.2K0.01%+12+1.2%Added
Evoke Wealth, LLC1,012$396.3K0.01%+96+10.5%Added
First Affirmative Financial Network1,015$397.5K0.19%−118−10.4%Reduced
Quest Partners LLC1,016$397.9K0.03%+561+123.3%Added
GeoWealth Management, LLC1,018$398.7K0.01%+64+6.7%Added
Parsonex Advisory Services, Inc.1,018$398.7K0.27%+218+27.3%Added
Great Valley Advisor Group, Inc.1,025$401.0K0.01%−186−15.4%Reduced
Fulton Bank, N.A.1,024$401.0K0.01%+177+20.9%Added
Investment Management Corp1,027$402.1K0.35%+21+2.1%Added
Sunbelt Securities, Inc.1,038$406.5K0.03%+3+0.3%Added
Jacobi Capital Management LLC1,042$408.1K0.02%+56+5.7%Added
Founders Financial Alliance, LLC1,045$409.3K0.08%+226+27.6%Added
TCG Advisory Services, LLC1,045$409.3K0.02%+1,045New