Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Congress Asset Management Co | 160,875 | $63.0M | 0.42% | −27,129−14.4% | Reduced |
| AQR Capital Management LLC | 161,683 | $63.3M | 0.04% | +20,147+14.2% | Added |
| AXA Investment Managers S.A. | 163,680 | $64.1M | 0.17% | +163,680 | New |
| Danske Bank A/S | 164,480 | $64.4M | 0.16% | −42,266−20.4% | Reduced |
| Mirae Asset Global ETFs Holdings Ltd. | 165,945 | $65.0M | 0.10% | −53,488−24.4% | Reduced |
| APG Asset Management N.V. | 200,588 | $66.9M | 0.19% | −1,364−0.7% | Reduced |
| Citadel Advisors LLC | 173,502 | $68.0M | 0.05% | +144,675+501.9% | Added |
| Candriam Luxembourg S.C.A. | 174,567 | $68.4M | 0.36% | −1,831−1.0% | Reduced |
| SEI Investments Co | 176,527 | $69.1M | 0.07% | −120,876−40.6% | Reduced |
| Tredje AP-fonden | 185,312 | $72.6M | 0.58% | −65,290−26.1% | Reduced |
| Federated Hermes, Inc. | 186,569 | $73.1M | 0.13% | −7,390−3.8% | Reduced |
| Carmignac Gestion | 187,539 | $73.5M | 1.09% | −39,757−17.5% | Reduced |
| First Trust Advisors LP | 188,161 | $73.7M | 0.05% | −99,731−34.6% | Reduced |
| Capital International Inc | 191,341 | $74.9M | 0.60% | +16,108+9.2% | Added |
| Aviva PLC | 204,889 | $80.2M | 0.15% | +12,229+6.3% | Added |
| Korea Investment CORP | 205,745 | $80.6M | 0.17% | +4,011+2.0% | Added |
| Baillie Gifford & Co | 207,056 | $81.1M | 0.06% | −5,423−2.6% | Reduced |
| New York State Teachers Retirement System | 212,829 | $83.4M | 0.16% | +9,325+4.6% | Added |
| Handelsbanken Fonder AB | 214,760 | $84.1M | 0.27% | +467+0.2% | Added |
| TD Asset Management Inc | 217,539 | $85.2M | 0.07% | −247,634−53.2% | Reduced |
| Davenport & Co LLC | 217,284 | $85.3M | 0.46% | −8,900−3.9% | Reduced |
| Welch & Forbes LLC | 220,346 | $86.3M | 1.04% | +3,102+1.4% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 220,801 | $86.5M | 0.27% | +14,706+7.1% | Added |
| Caisse de Depot Et Placement du Quebec | 222,262 | $87.0M | 0.16% | +157,866+245.1% | Added |
| Macquarie Group Ltd | 223,556 | $87.6M | 0.10% | −5,297−2.3% | Reduced |
| Capital International Sarl | 225,734 | $88.4M | 1.53% | +2,345+1.0% | Added |
| Prudential Financial Inc | 225,814 | $88.4M | 0.11% | +45,578+25.3% | Added |
| State Board of Administration of Florida Retirement System | 233,612 | $91.5M | 0.16% | −17,399−6.9% | Reduced |
| Canada Pension Plan Investment Board | 246,364 | $96.5M | 0.07% | +78,956+47.2% | Added |
| National Bank of Canada | 247,941 | $97.1M | 0.11% | +7,563+3.1% | Added |
| Jane Street Group, LLC | 248,267 | $97.2M | 0.11% | +248,267 | New |
| Swedbank AB | 254,096 | $99.5M | 0.10% | −251−0.1% | Reduced |
| BNP Paribas Arbitrage, SA | 254,343 | $99.6M | 0.08% | −276,845−52.1% | Reduced |
| Cerity Partners LLC | 258,808 | $101.4M | 0.16% | −4,884−1.9% | Reduced |
| LPL Financial LLC | 264,182 | $103.5M | 0.03% | +23,566+9.8% | Added |
| Alyeska Investment Group, L.P. | 267,169 | $104.6M | 0.32% | +202,169+311.0% | Added |
| Great West Life Assurance Co | 274,136 | $108.3M | 0.16% | +3,424+1.3% | Added |
| Royal London Asset Management Ltd | 277,196 | $108.6M | 0.23% | −6,149−2.2% | Reduced |
| New York State Common Retirement Fund | 308,577 | $120.9M | 0.16% | −31,695−9.3% | Reduced |
| Ensign Peak Advisors, Inc | 311,998 | $122.2M | 0.20% | +134,964+76.2% | Added |
| Standard Life Aberdeen plc | 314,889 | $123.3M | 0.20% | +26,922+9.3% | Added |
| B. Metzler seel. Sohn & Co. AG | 315,422 | $123.5M | 1.09% | −4,199−1.3% | Reduced |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 319,467 | $125.1M | 0.21% | +5,786+1.8% | Added |
| ProShare Advisors LLC | 333,732 | $130.7M | 0.27% | −67,512−16.8% | Reduced |
| Public Employees Retirement Association of Colorado | 336,091 | $131.6M | 0.48% | −56,452−14.4% | Reduced |
| Russell Investments Group, Ltd. | 341,048 | $133.7M | 0.15% | +27,326+8.7% | Added |
| Nordea Investment Management AB | 361,085 | $140.1M | 0.12% | +336,573+1,373.1% | Added |
| Man Group plc | 362,774 | $142.1M | 0.27% | +235,156+184.3% | Added |
| Bank Julius Baer & Co. Ltd, Zurich | 376,495 | $147.5M | 0.42% | −14,881−3.8% | Reduced |
| Robeco Institutional Asset Management B.V. | 379,371 | $148.6M | 0.22% | +49,980+15.2% | Added |
| Arrowstreet Capital, Limited Partnership | 381,195 | $149.3M | 0.09% | +319,725+520.1% | Added |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 388,311 | $152.1M | 0.35% | −6,060−1.5% | Reduced |
| California State Teachers Retirement System | 394,582 | $154.5M | 0.16% | −3,058−0.8% | Reduced |
| Principal Financial Group Inc | 406,500 | $159.2M | 0.08% | −3,305−0.8% | Reduced |
| Chevy Chase Trust Holdings, Inc. | 418,509 | $163.9M | 0.45% | −22,418−5.1% | Reduced |
| Bank of Montreal | 419,458 | $164.3M | 0.07% | +56,423+15.5% | Added |
| Voya Investment Management LLC | 432,257 | $168.8M | 0.17% | −267,387−38.2% | Reduced |
| Rhumbline Advisers | 447,928 | $175.4M | 0.14% | −6,444−1.4% | Reduced |
| American Century Companies Inc | 449,193 | $175.9M | 0.09% | −88,939−16.5% | Reduced |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 456,333 | $178.6M | 0.46% | +11,874+2.7% | Added |
| Harding Loevner LP | 455,988 | $178.6M | 1.31% | −255,623−35.9% | Reduced |
| Franklin Resources Inc | 462,954 | $181.3M | 0.05% | −60,879−11.6% | Reduced |
| Envestnet Asset Management Inc | 470,755 | $184.4M | 0.05% | +21,767+4.8% | Added |
| Manning & Napier Advisors LLC | 474,822 | $187.7M | 2.39% | +241,242+103.3% | Added |
| Adage Capital Partners GP, L.L.C. | 482,495 | $189.0M | 0.30% | +304,303+170.8% | Added |
| Massachusetts Financial Services Co | 503,160 | $197.1M | 0.06% | −781,194−60.8% | Reduced |
| Bellevue Group AG | 505,805 | $198.1M | 4.12% | +64,195+14.5% | Added |
| DekaBank Deutsche Girozentrale | 506,457 | $199.7M | 0.34% | 00.0% | Unchanged |
| Manufacturers Life Insurance Company, The | 510,165 | $199.8M | 0.16% | −36,791−6.7% | Reduced |
| National Pension Service | 512,113 | $200.6M | 0.16% | +14,313+2.9% | Added |
| Neuberger Berman Group LLC | 527,491 | $206.6M | 0.15% | +68,341+14.9% | Added |
| Raymond James Financial Inc | 535,685 | $209.8M | 0.07% | +35,908+7.2% | Added |
| Natixis Advisors, L.P. | 537,194 | $210.4M | 0.31% | −3,336−0.6% | Reduced |
| Citigroup Inc | 539,995 | $211.5M | 0.15% | −59,084−9.9% | Reduced |
| Lazard Asset Management LLC | 544,823 | $213.4M | 0.29% | +64,513+13.4% | Added |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 544,978 | $213.4M | 0.15% | +20,053+3.8% | Added |
| Squarepoint Ops LLC | 607,836 | $238.1M | 0.51% | +432,149+246.0% | Added |
| California Public Employees Retirement System | 612,507 | $239.9M | 0.14% | −112,548−15.5% | Reduced |
| HSBC Holdings PLC | 637,332 | $249.5M | 0.15% | −4,629−0.7% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 700,673 | $274.4M | 0.16% | +45,623+7.0% | Added |
| Wells Fargo & Company | 717,326 | $280.9M | 0.06% | +15,274+2.2% | Added |
| Renaissance Technologies LLC | 735,888 | $288.2M | 0.38% | −269,000−26.8% | Reduced |
| Swiss National Bank | 740,300 | $289.9M | 0.17% | −38,000−4.9% | Reduced |
| Barclays PLC | 742,487 | $290.8M | 0.11% | −80,450−9.8% | Reduced |
| Assenagon Asset Management S.A. | 763,703 | $299.1M | 0.44% | +520,949+214.6% | Added |
| UBS Group AG | 773,048 | $302.8M | 0.06% | +73,046+10.4% | Added |
| Dimensional Fund Advisors LP | 783,586 | $306.9M | 0.07% | +187,359+31.4% | Added |
| Pictet Asset Management Holding SA | 791,458 | $310.5M | 0.30% | +55,636+7.6% | Added |
| Nuveen, LLC | 1,077,710 | $422.1M | 0.11% | +15,475+1.5% | Added |
| Amundi | 1,118,971 | $450.8M | 0.14% | −14,255−1.3% | Reduced |
| WCM Investment Management, LLC | 1,150,132 | $454.7M | 0.95% | −13,538−1.2% | Reduced |
| Royal Bank of Canada | 1,193,709 | $467.5M | 0.08% | −190,659−13.8% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 1,341,470 | $525.4M | 0.47% | +135,674+11.3% | Added |
| Goldman Sachs Group Inc | 1,484,658 | $581.5M | 0.08% | −447,102−23.1% | Reduced |
| Edgewood Management LLC | 1,487,542 | $582.6M | 2.06% | −967,405−39.4% | Reduced |
| Bank of New York Mellon Corp | 1,569,165 | $614.5M | 0.11% | −31,308−2.0% | Reduced |
| Deutsche Bank AG | 1,600,456 | $626.8M | 0.21% | +192,822+13.7% | Added |
| Parnassus Investments | 1,648,433 | $645.6M | 1.49% | −63,007−3.7% | Reduced |
| Charles Schwab Investment Management Inc | 1,829,931 | $716.7M | 0.11% | +56,306+3.2% | Added |
| Legal & General Group Plc | 1,952,297 | $764.6M | 0.17% | +62,520+3.3% | Added |