Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q3 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,523
- −12 vs. Q2 2025
- Shares held
- 232.3M
- −4.81M (−2.0%) vs. Q2 2025
- Total value
- $90.8B
- −$14.7B (−14.0%) vs. Q2 2025
- New holders
- 143
- 553 more added
- Sold out
- 155
- 617 more reduced
28 institutions that held it in Q2 2025 haven't filed for Q3 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Atria Investments LLC | 25,919 | $10.2M | 0.12% | +2,418+10.3% | Added |
| Advisors Asset Management, Inc. | 25,926 | $10.2M | 0.17% | +841+3.4% | Added |
| Meritage Portfolio Management | 25,940 | $10.2M | 0.68% | −7,003−21.3% | Reduced |
| Fisher Asset Management, LLC | 25,959 | $10.2M | 0.00% | +204+0.8% | Added |
| Bogart Wealth, LLC | 26,149 | $10.2M | 0.42% | +742+2.9% | Added |
| Capital Group Investment Management Pte. Ltd. | 26,286 | $10.3M | 1.73% | −1,213−4.4% | Reduced |
| ASR Vermogensbeheer N.V. | 26,294 | $10.3M | 0.12% | −125−0.5% | Reduced |
| Fagan Associates, Inc. | 26,306 | $10.3M | 1.42% | +111+0.4% | Added |
| Bender Robert & Associates | 26,330 | $10.3M | 2.23% | −382−1.4% | Reduced |
| Sig Brokerage, LP | 26,390 | $10.3M | 2.60% | −6,176−19.0% | Reduced |
| Profund Advisors LLC | 26,395 | $10.3M | 0.34% | −958−3.5% | Reduced |
| Susquehanna Portfolio Strategies, LLC | 26,784 | $10.5M | 0.17% | +26,784 | New |
| Avanza Fonder AB | 27,053 | $10.6M | 0.27% | +1,628+6.4% | Added |
| Steward Partners Investment Advisory, LLC | 27,361 | $10.7M | 0.06% | −14,190−34.2% | Reduced |
| Shelter Mutual Insurance Co | 27,600 | $10.8M | 2.42% | 00.0% | Unchanged |
| Mutual of America Capital Management LLC | 27,746 | $10.9M | 0.11% | −1,660−5.6% | Reduced |
| Y-Intercept (Hong Kong) Ltd | 27,770 | $10.9M | 0.26% | +27,770 | New |
| OP Asset Management Ltd | 28,288 | $11.1M | 0.15% | +511+1.8% | Added |
| CCM Investment Advisers LLC | 28,309 | $11.1M | 1.09% | −1,306−4.4% | Reduced |
| Massmutual Trust Co FSB | 28,495 | $11.2M | 0.28% | +1,704+6.4% | Added |
| Oregon Public Employees Retirement Fund | 29,285 | $11.5M | 0.15% | +7,101+32.0% | Added |
| Apollon Wealth Management, LLC | 29,366 | $11.5M | 0.20% | −391−1.3% | Reduced |
| Huntington National Bank | 29,447 | $11.5M | 0.07% | −3,965−11.9% | Reduced |
| Aquatic Capital Management LLC | 29,596 | $11.6M | 0.22% | +29,596 | New |
| Natixis | 29,806 | $11.7M | 0.06% | −1,155−3.7% | Reduced |
| Washington Trust Bank | 29,809 | $11.7M | 0.86% | +566+1.9% | Added |
| Headlands Technologies LLC | 29,864 | $11.7M | 0.93% | +29,864 | New |
| Liontrust Investment Partners LLP | 30,300 | $11.9M | 0.17% | +3,346+12.4% | Added |
| US Bancorp | 30,856 | $12.1M | 0.01% | −2,727−8.1% | Reduced |
| Louisiana State Employees Retirement System | 32,200 | $12.6M | 0.21% | −100−0.3% | Reduced |
| Barlow Wealth Partners, Inc. | 29,880 | $12.7M | 1.42% | −21,078−41.4% | Reduced |
| Galvin, Gaustad & Stein, LLC | 33,142 | $13.0M | 1.06% | +10,252+44.8% | Added |
| McRae Capital Management Inc | 33,159 | $13.0M | 2.58% | +2,706+8.9% | Added |
| Oddo BHF Asset Management SAS | 33,278 | $13.0M | 0.50% | +20,890+168.6% | Added |
| Elo Mutual Pension Insurance Co | 33,783 | $13.2M | 0.22% | +491+1.5% | Added |
| MML Investors Services, LLC | 34,231 | $13.4M | 0.04% | −2,376−6.5% | Reduced |
| Intech Investment Management LLC | 34,361 | $13.5M | 0.12% | +16,873+96.5% | Added |
| Sapient Capital LLC | 34,311 | $13.6M | 0.21% | −1,999−5.5% | Reduced |
| Bailard, Inc. | 34,639 | $13.6M | 0.29% | −3,508−9.2% | Reduced |
| Flputnam Investment Management Co | 34,676 | $13.6M | 0.20% | −3,065−8.1% | Reduced |
| Foster Victor Wealth Advisors, LLC | 33,857 | $13.7M | 0.85% | +8,493+33.5% | Added |
| Varma Mutual Pension Insurance Co | 34,926 | $13.7M | 0.09% | −1,700−4.6% | Reduced |
| Adams Diversified Equity Fund, Inc. | 35,100 | $13.7M | 0.46% | 00.0% | Unchanged |
| Vestcor Inc | 35,266 | $13.8M | 0.41% | +3,778+12.0% | Added |
| Los Angeles Capital Management LLC | 35,472 | $13.9M | 0.05% | +2,458+7.4% | Added |
| O'Shaughnessy Asset Management, LLC | 35,681 | $14.0M | 0.08% | +1,422+4.2% | Added |
| iA Global Asset Management Inc. | 35,842 | $14.0M | 0.19% | +685+1.9% | Added |
| State of Alaska, Department of Revenue | 35,853 | $14.0M | 0.14% | −9,402−20.8% | Reduced |
| Andra AP-fonden | 35,900 | $14.1M | 0.18% | +35,900 | New |
| Cornerstone Advisors, LLC | 36,100 | $14.1M | 0.47% | −500−1.4% | Reduced |
| Martingale Asset Management L P | 36,522 | $14.3M | 0.36% | −4,760−11.5% | Reduced |
| Shelton Capital Management | 36,679 | $14.4M | 0.31% | −16,336−30.8% | Reduced |
| JustInvest LLC | 37,000 | $14.5M | 0.15% | −1,491−3.9% | Reduced |
| Virginia Retirement Systems Et Al | 37,100 | $14.5M | 0.09% | +37,100 | New |
| Wealthfront Advisers LLC | 37,373 | $14.6M | 0.03% | −6,545−14.9% | Reduced |
| New York Life Investment Management LLC | 37,432 | $14.7M | 0.13% | −1,468−3.8% | Reduced |
| Pathstone Holdings, LLC | 37,879 | $14.8M | 0.06% | +1,446+4.0% | Added |
| Bridgewater Associates, LP | 38,324 | $15.0M | 0.06% | +3,934+11.4% | Added |
| Ilmarinen Mutual Pension Insurance Co | 38,800 | $15.2M | 0.11% | −6,000−13.4% | Reduced |
| Tweedy, Browne Co LLC | 39,065 | $15.3M | 1.33% | +1,812+4.9% | Added |
| Aristotle Atlantic Partners, LLC | 39,804 | $15.6M | 0.45% | −5,572−12.3% | Reduced |
| Armistice Capital, LLC | 40,239 | $15.8M | 0.49% | +40,239 | New |
| Boston Common Asset Management, LLC | 40,899 | $16.0M | 0.45% | −5,164−11.2% | Reduced |
| Segall Bryant & Hamill, LLC | 40,971 | $16.0M | 0.21% | −1,357−3.2% | Reduced |
| Gradient Investments LLC | 40,977 | $16.0M | 0.27% | +2,964+7.8% | Added |
| Millennium Management LLC | 41,042 | $16.1M | 0.01% | +41,042 | New |
| Police & Firemen's Retirement System of New Jersey | 41,376 | $16.2M | 0.13% | +2,341+6.0% | Added |
| Utah Retirement Systems | 42,499 | $16.6M | 0.16% | −34−0.1% | Reduced |
| Teachers Retirement System of the State of Kentucky | 42,581 | $16.7M | 0.13% | −25,599−37.5% | Reduced |
| Citizens Financial Group Inc | 42,881 | $16.8M | 0.23% | +9,963+30.3% | Added |
| Groupama Asset Managment | 43,381 | $17.0M | 0.25% | −17,916−29.2% | Reduced |
| W.G. Shaheen & Associates DBA Whitney & Co | 43,556 | $17.1M | 1.55% | −253−0.6% | Reduced |
| HighTower Advisors, LLC | 44,015 | $17.2M | 0.02% | −12,332−21.9% | Reduced |
| USS Investment Management Ltd | 44,099 | $17.3M | 0.08% | −55−0.1% | Reduced |
| La Banque Postale Asset Management SA | 44,279 | $17.3M | 0.21% | +4,938+12.6% | Added |
| CIBC Bancorp USA Inc. | 44,774 | $17.5M | 0.11% | +44,774 | New |
| China Universal Asset Management Co., Ltd. | 45,114 | $17.7M | 1.46% | +849+1.9% | Added |
| Hudson Bay Capital Management LP | 45,315 | $17.7M | 0.11% | −4,931−9.8% | Reduced |
| Calamos Advisors LLC | 45,753 | $17.9M | 0.07% | 00.0% | Unchanged |
| Marshall Wace, LLP | 45,885 | $18.0M | 0.02% | −71,115−60.8% | Reduced |
| C WorldWide Group Holding A/S | 46,057 | $18.0M | 0.28% | 00.0% | Unchanged |
| Sanctuary Advisors, LLC | 46,253 | $18.1M | 0.10% | −917−1.9% | Reduced |
| Rhenman & Partners Asset Management AB | 46,955 | $18.4M | 2.03% | −14,500−23.6% | Reduced |
| IFM Investors Pty Ltd | 49,484 | $19.1M | 0.17% | −833−1.7% | Reduced |
| Smith Group Asset Management, LLC | 48,857 | $19.1M | 1.10% | +2,602+5.6% | Added |
| Hallmark Capital Management Inc | 49,819 | $19.5M | 1.29% | +1,130+2.3% | Added |
| Tudor Investment Corp Et Al | 51,374 | $20.1M | 0.13% | +51,374 | New |
| Qube Research & Technologies Ltd | 51,382 | $20.1M | 0.03% | +45,701+804.5% | Added |
| Cullinan Associates Inc | 51,412 | $20.1M | 1.31% | −600−1.2% | Reduced |
| Illinois Municipal Retirement Fund | 52,801 | $20.7M | 0.26% | −823−1.5% | Reduced |
| Lido Advisors, LLC | 53,695 | $21.0M | 0.09% | +7,873+17.2% | Added |
| Mackenzie Financial Corp | 54,343 | $21.3M | 0.03% | +18,068+49.8% | Added |
| Retirement Systems of Alabama | 54,693 | $21.4M | 0.07% | −409−0.7% | Reduced |
| Sumitomo Mitsui DS Asset Management Company, Ltd | 54,994 | $21.5M | 0.17% | +6,904+14.4% | Added |
| Forsta Ap-Fonden | 55,000 | $21.5M | 0.13% | +3,000+5.8% | Added |
| Artia Global Partners LP | 55,100 | $21.6M | 3.80% | +50,700+1,152.3% | Added |
| Hemenway Trust Co LLC | 55,125 | $21.6M | 1.65% | −390−0.7% | Reduced |
| Edgemoor Investment Advisors, Inc. | 55,194 | $21.6M | 1.67% | −830−1.5% | Reduced |
| Atwood & Palmer Inc | 55,297 | $21.7M | 1.27% | +105+0.2% | Added |
| Reynders McVeigh Capital Management, LLC | 55,350 | $21.7M | 1.02% | +1,040+1.9% | Added |