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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 1 sale; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Lifeworks Advisors, LLC2,654$1.18M0.18%−501−15.9%Reduced
Voleon Capital Management LP2,693$1.20M0.07%−3,060−53.2%Reduced
Thurston, Springer, Miller, Herd & Titak, Inc.2,727$1.21M0.16%+553+25.4%Added
LGT Group Foundation2,739$1.22M0.02%−649−19.2%Reduced
Westpac Banking Corp2,745$1.22M0.08%+72+2.7%Added
Park Circle Co2,764$1.23M1.05%00.0%Unchanged
Sowell Financial Services LLC2,797$1.25M0.05%−29−1.0%Reduced
Westerkirk Capital Inc.2,800$1.25M0.15%+2,800New
Graypoint LLC2,839$1.26M0.07%−75−2.6%Reduced
Skopos Labs, Inc.2,847$1.27M0.17%+167+6.2%Added
MBM Wealth Consultants, LLC2,875$1.28M0.34%+103+3.7%Added
Pure Financial Advisors, Inc.2,891$1.29M0.02%+2,062+248.7%Added
Connecticut Wealth Management, LLC2,892$1.29M0.06%−11−0.4%Reduced
Farther Finance Advisors, LLC2,906$1.29M0.03%+35+1.2%Added
Baker Tilly Wealth Management, LLC2,908$1.29M0.46%−80−2.7%Reduced
Independent Advisor Alliance2,909$1.30M0.04%+81+2.9%Added
Brown Brothers Harriman & Co2,922$1.30M0.01%+92+3.3%Added
Dynamic Advisor Solutions LLC2,939$1.31M0.04%+148+5.3%Added
Strategy Asset Managers LLC2,942$1.31M0.24%+99+3.5%Added
Prosperity Consulting Group, LLC2,950$1.31M0.10%−54−1.8%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC2,950$1.31M0.05%+648+28.1%Added
Trust Asset Management LLC2,962$1.32M0.10%00.0%Unchanged
Legacy Financial Advisors, Inc.2,981$1.33M0.21%−105−3.4%Reduced
Prime Capital Investment Advisors, LLC2,996$1.33M0.02%−735−19.7%Reduced
J. Safra Sarasin Holding AG3,000$1.34M0.02%−946−24.0%Reduced
Dakota Wealth Management3,010$1.34M0.03%−7,137−70.3%Reduced
Altshuler Shaham Ltd3,020$1.34M0.04%00.0%Unchanged
Simplicity Wealth,LLC3,035$1.35M0.06%+1,736+133.6%Added
Pallas Capital Advisors LLC3,059$1.36M0.05%+579+23.3%Added
VestGen Advisors, LLC3,061$1.36M0.05%−202−6.2%Reduced
Patriot Financial Group Insurance Agency, LLC3,076$1.37M0.16%+15+0.5%Added
Landscape Capital Management, L.L.C.3,079$1.37M0.11%−398−11.4%Reduced
FRG Family Wealth Advisors LLC3,080$1.37M0.24%−50−1.6%Reduced
Cherry Creek Investment Advisors, Inc.3,108$1.38M0.65%−71−2.2%Reduced
Arjuna Capital3,110$1.38M0.36%−890−22.3%Reduced
Concurrent Investment Advisors, LLC3,120$1.39M0.03%−93−2.9%Reduced
L & S Advisors Inc3,146$1.40M0.14%−158−4.8%Reduced
Wealthcare Advisory Partners LLC3,162$1.41M0.03%−29−0.9%Reduced
NorthRock Partners, LLC3,176$1.41M0.04%−98−3.0%Reduced
Sculati Wealth Management, LLC3,179$1.42M0.53%+242+8.2%Added
Sagespring Wealth Partners, LLC3,185$1.42M0.03%−45−1.4%Reduced
Portside Wealth Group, LLC3,198$1.42M0.21%+253+8.6%Added
Stratos Wealth Partners, LTD.3,201$1.43M0.02%−1,083−25.3%Reduced
WP Advisors, LLC3,208$1.43M0.39%+9+0.3%Added
Alaethes Wealth LLC3,209$1.43M0.43%+158+5.2%Added
ICICI Prudential Asset Management Co Ltd3,218$1.43M0.18%−75−2.3%Reduced
Aaron Wealth Advisors3,219$1.43M0.15%−88−2.7%Reduced
Abc Arbitrage SA3,221$1.43M0.16%+3,221New
Frank, Rimerman Advisors LLC3,246$1.45M0.10%−304−8.6%Reduced
Atria Wealth Solutions, Inc.3,254$1.45M0.03%−3,402−51.1%Reduced
Ingalls & Snyder LLC3,284$1.46M0.05%−40−1.2%Reduced
Arrow Financial Corp3,302$1.47M0.15%−83−2.5%Reduced
Westbourne Investments, Inc.3,306$1.47M0.78%00.0%Unchanged
Camden Capital, LLC3,309$1.47M0.14%+139+4.4%Added
Syon Capital LLC3,320$1.48M0.10%+13+0.4%Added
Murphy & Mullick Capital Management Corp3,254$1.49M1.21%−6−0.2%Reduced
Berkshire Asset Management LLC3,370$1.50M0.07%00.0%Unchanged
Stephens Inc3,392$1.51M0.02%+77+2.3%Added
Panagora Asset Management Inc3,408$1.52M0.01%−11−0.3%Reduced
Institute for Wealth Management, LLC.3,423$1.52M0.17%−91−2.6%Reduced
Midwest Professional Planners, LTD.3,425$1.52M0.40%−30−0.9%Reduced
Moody National Bank Trust Division3,441$1.53M0.14%−92−2.6%Reduced
Triglav Skladi, D.O.O.3,450$1.54M0.11%00.0%Unchanged
Mutual Advisors, LLC3,275$1.54M0.04%+191+6.2%Added
Allworth Financial LP3,462$1.54M0.01%+1,516+77.9%Added
Tealwood Asset Management Inc3,466$1.54M0.69%−83−2.3%Reduced
Ifrah Financial Services, Inc.3,501$1.56M0.43%−44−1.2%Reduced
Clearstead Advisors, LLC3,520$1.57M0.02%−34−1.0%Reduced
DSG Capital Advisors, LLC3,545$1.58M0.28%−80−2.2%Reduced
Roberts Glore & Co Inc3,622$1.61M0.47%−121−3.2%Reduced
Sound View Wealth Advisors Group, LLC3,624$1.61M0.12%+94+2.7%Added
Cooper Financial Group3,644$1.62M0.19%−993−21.4%Reduced
Ritholtz Wealth Management3,662$1.63M0.04%+203+5.9%Added
Bryn Mawr Trust Co3,664$1.63M0.03%+7+0.2%Added
Ashton Thomas Securities, LLC3,691$1.64M0.40%+12+0.3%Added
Nilsine Partners, LLC3,725$1.66M0.17%+5+0.1%Added
Lighthouse Financial LLC3,730$1.66M1.27%00.0%Unchanged
Coastline Trust Co3,742$1.67M0.19%00.0%Unchanged
Roman Butler Fullerton & Co3,577$1.68M0.50%+489+15.8%Added
ZWJ Investment Counsel Inc3,777$1.68M0.06%+13+0.3%Added
Belpointe Asset Management LLC3,780$1.68M0.07%−225−5.6%Reduced
Capital Investment Advisory Services, LLC3,780$1.68M0.14%−198−5.0%Reduced
Intrust Bank NA3,803$1.69M0.15%+197+5.5%Added
JT Stratford LLC3,814$1.70M0.26%−98−2.5%Reduced
Oppenheimer & Co Inc3,841$1.71M0.02%−2,360−38.1%Reduced
Canada Post Corp Registered Pension Plan3,854$1.72M0.10%−250−6.1%Reduced
Principal Street Partners, LLC3,871$1.72M0.17%+1,535+65.7%Added
Mattson Financial Services, LLC3,903$1.74M0.47%+3,903New
Cambria Investment Management, L.P.3,910$1.74M0.12%+3,910New
Summit Global Investments3,912$1.74M0.10%+342+9.6%Added
Laffer Tengler Investments3,926$1.75M0.31%−227−5.5%Reduced
Snowden Capital Advisors LLC3,957$1.76M0.05%−640−13.9%Reduced
Texas Yale Capital Corp.3,968$1.77M0.06%−125−3.1%Reduced
SageView Advisory Group, LLC3,845$1.77M0.07%−133−3.3%Reduced
Future Fund LLC4,003$1.78M0.80%−346−8.0%Reduced
Woodstock Corp4,005$1.78M0.16%−172−4.1%Reduced
GKV Capital Management Co., Inc.4,028$1.79M0.79%+100+2.5%Added
HighPoint Advisor Group LLC4,037$1.80M0.10%+26+0.6%Added
STF Management LP4,095$1.82M0.72%+96+2.4%Added
S&CO Inc4,103$1.83M0.12%00.0%Unchanged