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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Aureus Asset Management, LLC1,818$809.4K0.05%−335−15.6%Reduced
Whittier Trust Co1,820$810.3K0.01%−104−5.4%Reduced
Capital Advisors Wealth Management, LLC1,821$810.7K0.13%−47−2.5%Reduced
We Are One Seven, LLC1,822$811.2K0.03%+43+2.4%Added
Fifth Third Wealth Advisors LLC1,826$812.9K0.03%−8−0.4%Reduced
Premier Path Wealth Partners, LLC1,835$817.1K0.11%+45+2.5%Added
Breakwater Capital Group1,839$818.7K0.13%+53+3.0%Added
Aviso Financial Inc.1,844$820.9K0.04%−6−0.3%Reduced
Legal Advantage Investments, Inc.1,848$822.7K0.38%00.0%Unchanged
Groesbeck Investment Management Corp1,859$828.0K1.45%−10−0.5%Reduced
PFG Investments, LLC1,872$833.4K0.05%+60+3.3%Added
Spears Abacus Advisors LLC1,872$833.4K0.02%−37−1.9%Reduced
Summit Financial, LLC1,873$833.9K0.02%+233+14.2%Added
Livforsakringsbolaget Skandia, Omsesidigt1,880$836.7K0.04%−25,740−93.2%Reduced
Everhart Financial Group, Inc.1,881$837.4K0.10%−328−14.8%Reduced
Badgley Phelps Wealth Managers, LLC1,887$840.1K0.02%+22+1.2%Added
Geneos Wealth Management Inc.1,892$842.3K0.02%+65+3.6%Added
Goelzer Investment Management, Inc.1,899$845.4K0.05%+6+0.3%Added
Malaga Cove Capital, LLC1,912$851.2K0.33%+123+6.9%Added
Menard Financial Group LLC1,951$868.6K0.52%+169+9.5%Added
Proficio Capital Partners LLC1,955$870.4K0.05%−124−6.0%Reduced
Bryce Point Capital, LLC1,956$870.8K0.74%+710+57.0%Added
Annis Gardner Whiting Capital Advisors, LLC1,961$873.0K0.30%+22+1.1%Added
Community Bank, N.A.1,964$874.4K0.11%+727+58.8%Added
Bradley Foster & Sargent Inc1,971$877.5K0.01%−121−5.8%Reduced
Prossimo Advisors, LLC1,975$879.0K0.71%−80−3.9%Reduced
Holt Capital Advisors, L.L.C. dba Holt Capital Partners, L.P.1,977$880.2K0.15%00.0%Unchanged
IFG Advisory, LLC1,985$883.7K0.04%+3+0.2%Added
Veracity Capital LLC1,994$887.7K0.31%−108−5.1%Reduced
Towarzystwo Funduszy Inwestycyjnych Pzu SA1,994$887.7K0.25%−75−3.6%Reduced
Allegheny Financial Group LTD2,000$890.4K0.20%00.0%Unchanged
Mystic Asset Management, Inc.2,000$890.4K0.22%00.0%Unchanged
Qtron Investments LLC2,016$897.5K0.11%00.0%Unchanged
Guidance Capital, Inc1,943$897.9K0.26%−332−14.6%Reduced
Pflug Koory, LLC2,046$910.9K0.46%+52+2.6%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management2,052$913.6K0.02%+215+11.7%Added
Fort Sheridan Advisors LLC2,076$924.2K0.13%−352−14.5%Reduced
Integrated Advisors Network LLC2,080$926.2K0.04%−76−3.5%Reduced
Csenge Advisory Group2,096$926.5K0.05%−85−3.9%Reduced
Schmidt P J Investment Management Inc2,082$926.9K0.16%+150+7.8%Added
Formidable Asset Management, LLC2,019$931.1K0.16%−82−3.9%Reduced
Forum Financial Management, LP2,094$932.4K0.01%00.0%Unchanged
Ashton Thomas Private Wealth, LLC2,122$944.7K0.03%−220−9.4%Reduced
Hohimer Wealth Management, LLC2,123$945.2K0.17%+26+1.2%Added
Presilium Private Wealth, LLC2,124$945.6K0.19%00.0%Unchanged
MAI Capital Management2,127$946.8K0.01%+209+10.9%Added
Evercore Wealth Management, LLC2,128$947.4K0.01%+27+1.3%Added
Impact Capital Partners LLC2,139$952.3K0.31%−337−13.6%Reduced
Mitchell & Pahl Private Wealth, LLC2,144$954.5K0.42%−5−0.2%Reduced
Alliance Wealth Advisors, LLC2,145$955.0K0.24%+572+36.4%Added
Arkadios Wealth Advisors2,152$958.2K0.03%+697+47.9%Added
Regal Investment Advisors LLC2,171$966.3K0.07%+366+20.3%Added
Koa Wealth Management, LLC2,180$970.5K0.77%+108+5.2%Added
HM Payson & Co2,198$978.5K0.02%−3,623−62.2%Reduced
Global Retirement Partners, LLC2,205$981.9K0.02%+2,205New
Kane Investment Management, Inc.2,231$993.2K0.52%−89−3.8%Reduced
S-Bank Fund Management Ltd2,233$994.1K0.15%−157−6.6%Reduced
Advisors Preferred, LLC2,200$994.8K0.16%00.0%Unchanged
Equitable Holdings, Inc.2,237$995.9K0.01%+85+3.9%Added
Cravens & Co Advisors, LLC2,241$997.7K0.74%+63+2.9%Added
Brown Financial Advisors2,253$1.00M0.39%+2,253New
Sigma Planning Corp2,280$1.01M0.03%−34−1.5%Reduced
GraniteShares Advisors LLC2,286$1.02M0.63%−28−1.2%Reduced
Umb Bank N A2,303$1.03M0.02%−1,094−32.2%Reduced
Persistent Asset Partners Ltd2,303$1.03M0.90%+2,303New
Mirabella Financial Services LLP2,299$1.03M0.11%−54,584−96.0%Reduced
Mattern Capital Management, LLC2,332$1.04M0.12%+396+20.5%Added
Legacy Bridge, LLC2,332$1.04M0.49%00.0%Unchanged
Adviser Investments LLC2,343$1.04M0.01%−142−5.7%Reduced
Baader Bank INC2,357$1.05M0.09%+1,247+112.3%Added
Capstone Investment Advisors, LLC2,359$1.05M0.01%+2,359New
West Family Investments, Inc.2,363$1.05M0.27%+1,015+75.3%Added
NVWM, LLC2,367$1.05M0.25%−16−0.7%Reduced
Centaurus Financial, Inc.2,372$1.06M0.06%+61+2.6%Added
Argent Trust Co2,398$1.07M0.04%−506−17.4%Reduced
MN Wealth Advisors, LLC2,408$1.07M0.62%−16−0.7%Reduced
Phoenix Holdings Ltd.2,440$1.09M0.01%+2,440New
My Legacy Advisors, LLC2,263$1.09M0.39%+63+2.9%Added
Smartleaf Asset Management LLC2,463$1.09M0.10%−385−13.5%Reduced
1858 Wealth Management, LLC2,463$1.10M0.81%−375−13.2%Reduced
TownSquare Capital, LLC2,467$1.10M0.11%−20,519−89.3%Reduced
AE Wealth Management LLC2,468$1.10M0.01%+1,304+112.0%Added
SWS Partners2,482$1.11M0.30%+2,482New
Humankind Investments LLC2,489$1.11M0.27%+494+24.8%Added
Dorsey & Whitney Trust CO LLC2,493$1.11M0.06%−207−7.7%Reduced
Westport Asset Management Inc2,500$1.11M0.49%00.0%Unchanged
Strid Group, LLC2,500$1.11M0.16%+2,500New
Dana Investment Advisors, Inc.2,507$1.12M0.04%−142−5.4%Reduced
Savant Capital, LLC2,515$1.12M0.01%+327+14.9%Added
Clal Insurance Enterprises Holdings Ltd2,520$1.12M0.01%+2,465+4,481.8%Added
Atomi Financial Group, Inc.2,525$1.12M0.04%−318−11.2%Reduced
Headinvest, LLC2,530$1.13M0.24%−476−15.8%Reduced
Cigna Investments Inc2,539$1.13M0.19%−63−2.4%Reduced
Claro Advisors LLC2,546$1.13M0.19%−392−13.3%Reduced
Milestone Asset Management, LLC2,548$1.13M0.24%+2,548New
Norden Group LLC2,575$1.15M0.12%+787+44.0%Added
Icon Wealth Advisors, LLC2,585$1.15M0.08%+88+3.5%Added
Exchange Traded Concepts, LLC2,586$1.15M0.01%−37−1.4%Reduced
Hobbs Group Advisors, LLC2,608$1.16M0.40%−599−18.7%Reduced
Evergreen Capital Management LLC2,649$1.18M0.04%−149−5.3%Reduced