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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,564
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
619 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Cozad Asset Management Inc900$400.7K0.04%00.0%Unchanged
Two Sigma Advisers, LP900$400.7K0.00%+900New
Granite Bay Wealth Management, LLC900$401.0K0.13%+300+50.0%Added
Defined Wealth Management, LLC905$402.9K0.25%−17−1.8%Reduced
Optas, LLC907$403.8K0.08%−875−49.1%Reduced
Savvy Advisors, Inc.907$403.8K0.03%+285+45.8%Added
Evoke Wealth, LLC916$407.8K0.01%−257−21.9%Reduced
Cynosure Management, LLC918$408.7K0.05%+215+30.6%Added
J2 Capital Management Inc928$413.1K0.33%+250+36.9%Added
PUREfi Wealth, LLC936$416.7K0.33%+42+4.7%Added
Sunbelt Securities, Inc.1,035$416.8K0.04%00.0%Unchanged
TRUE Private Wealth Advisors945$420.6K0.05%−1−0.1%Reduced
EverSource Wealth Advisors, LLC946$420.9K0.02%+380+67.1%Added
Dohj, LLC857$422.0K0.12%+857New
HMS Capital Management, LLC948$422.1K0.19%−122−11.4%Reduced
MQS Management LLC950$422.9K0.23%+950New
Kraematon Investment Advisors, Inc951$423.5K0.40%−4−0.4%Reduced
GeoWealth Management, LLC954$424.7K0.02%−89−8.5%Reduced
Koss-Olinger Consulting, LLC957$426.0K0.03%−41−4.1%Reduced
Virtus Investment Advisers, Inc.966$430.1K0.15%+193+25.0%Added
Guardian Asset Advisors, LLC967$430.5K0.25%+67+7.4%Added
Investment House LLC969$431.4K0.02%−75−7.2%Reduced
Atom Investors LP970$431.8K0.04%+970New
Private Trust Co NA986$438.7K0.04%+21+2.2%Added
Jacobi Capital Management LLC986$439.0K0.03%+22+2.3%Added
RiverFront Investment Group, LLC987$439.4K0.01%+375+61.3%Added
Davis Investment Partners, LLC972$439.5K0.16%00.0%Unchanged
Washington Growth Strategies LLC998$444.0K0.34%+513+105.8%Added
SK Wealth Management, LLC927$444.0K0.19%−530−36.4%Reduced
Capital Investment Advisors, LLC997$444.0K0.01%−35−3.4%Reduced
Schwartz Investment Counsel Inc1,000$445.2K0.01%00.0%Unchanged
NJ State Employees Deferred Compensation Plan1,000$445.2K0.05%00.0%Unchanged
Legacy Capital Wealth Partners, LLC1,000$445.2K0.10%+50+5.3%Added
Foundations Investment Advisors, LLC1,002$446.1K0.01%+9+0.9%Added
Klingenstein Fields & Co LP1,005$447.4K0.02%00.0%Unchanged
Investment Management Corp1,006$447.7K0.41%+14+1.4%Added
Natural Investments, LLC1,016$452.0K0.12%+199+24.4%Added
17 Capital Partners, LLC1,020$454.1K0.26%+20+2.0%Added
SRS Capital Advisors, Inc.1,023$455.4K0.02%−5−0.5%Reduced
Richardson Financial Services Inc.1,020$461.2K0.31%+6+0.6%Added
TFB Advisors LLC1,039$462.6K0.12%+16+1.6%Added
J. Goldman & Co LP1,045$465.2K0.01%+1,045New
Parallax Volatility Advisers, L.P.1,046$465.7K0.02%+1,043+34,766.7%Added
Guardian Wealth Advisors, LLC1,052$468.1K0.03%−24−2.2%Reduced
Interchange Capital Partners, LLC1,052$468.3K0.11%−36−3.3%Reduced
Baker Ellis Asset Management LLC1,052$468.4K0.06%−221−17.4%Reduced
GPS Wealth Strategies Group, LLC1,059$471.5K0.05%−10−0.9%Reduced
New England Research & Management, Inc.1,060$472.0K0.22%+1,060New
Modern Wealth Management, LLC1,061$472.2K0.01%+115+12.2%Added
Symphony Financial, Ltd. Co.2,353$475.9K0.06%+2,353New
Quotient Wealth Partners, LLC1,071$476.8K0.01%−59−5.2%Reduced
Simplify Asset Management Inc.1,081$481.3K0.03%−114−9.5%Reduced
D.B. Root & Company, LLC1,082$481.7K0.14%−27−2.4%Reduced
Invesco, LLC1,091$485.7K0.18%00.0%Unchanged
Blue Chip Partners, Inc.1,106$492.4K0.04%+265+31.5%Added
Albion Financial Group1,113$495.5K0.03%00.0%Unchanged
Gryphon Financial Partners LLC1,123$500.0K0.07%+5+0.4%Added
Accurate Wealth Management, LLC1,044$500.4K0.08%−385−26.9%Reduced
David Loasby1,085$501.4K0.04%+148+15.8%Added
First Affirmative Financial Network1,133$504.2K0.26%+19+1.7%Added
Williams Jones Wealth Management, LLC.1,134$504.9K0.01%00.0%Unchanged
Davis R M Inc1,135$505.1K0.01%+4+0.4%Added
Personal Cfo Solutions, LLC1,137$506.2K0.09%−22−1.9%Reduced
Orrstown Financial Services Inc1,137$506.2K0.11%+160+16.4%Added
Keynote Financial Services LLC1,145$509.8K0.34%+40+3.6%Added
LCM Capital Management Inc1,148$511.1K0.27%+4+0.3%Added
Bridgewater Advisors Inc.1,097$513.9K0.04%−16−1.4%Reduced
Founders Financial Securities LLC1,155$514.2K0.04%−12−1.0%Reduced
Catalyst Financial Partners LLC1,170$520.9K0.06%−191−14.0%Reduced
Kestra Investment Management, LLC1,135$529.0K0.01%+538+90.1%Added
Avidian Wealth Solutions, LLC1,192$530.7K0.02%−33−2.7%Reduced
Generali Investments Towarzystwo Funduszy Inwestycyjnych1,200$534.2K0.28%00.0%Unchanged
First Commonwealth Financial Corp1,202$535.1K0.12%00.0%Unchanged
Chicago Partners Investment Group LLC1,124$536.1K0.02%+176+18.6%Added
Great Valley Advisor Group, Inc.1,211$539.5K0.01%−10,372−89.5%Reduced
Holocene Advisors, LP1,216$541.4K0.00%00.0%Unchanged
Willner & Heller, LLC1,216$541.4K0.46%+60+5.2%Added
Green Harvest Asset Management LLC1,220$543.1K0.01%−24−1.9%Reduced
TrueWealth Advisors, LLC1,223$544.5K0.16%+135+12.4%Added
Morningstar Investment Management LLC1,230$548.0K0.05%+1,230New
Platform Technology Partners1,234$549.4K0.14%−31−2.5%Reduced
Alps Advisors Inc1,239$551.6K0.00%−78−5.9%Reduced
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors1,240$552.0K0.08%−87−6.6%Reduced
Paladin Wealth, LLC1,240$552.0K0.43%+1,240New
PDS Planning, Inc1,243$553.4K0.04%+85+7.3%Added
Moneta Group Investment Advisors LLC1,246$554.9K0.01%+74+6.3%Added
Drive Wealth Management, LLC1,249$555.9K0.12%+176+16.4%Added
Merrion Investment Management Co, LLC1,250$556.5K0.36%00.0%Unchanged
Rathbone Brothers plc1,251$556.9K0.00%00.0%Unchanged
Breed's Hill Capital LLC1,253$557.8K0.27%+27+2.2%Added
Pensionmark Financial Group, LLC1,253$557.9K0.01%+379+43.4%Added
Fragasso Group Inc.1,254$558.3K0.04%+143+12.9%Added
RMB Capital Management, LLC1,256$559.0K0.01%+835+198.3%Added
BOK Financial Private Wealth, Inc.1,258$560.1K0.04%−531−29.7%Reduced
Total Clarity Wealth Management, Inc.1,262$561.8K0.16%+50+4.1%Added
Harel Insurance Investments & Financial Services Ltd.1,270$565.0K0.01%+504+65.8%Added
Alta Advisers Ltd1,271$565.8K0.20%00.0%Unchanged
Wakefield Asset Management LLLP1,276$568.1K0.16%00.0%Unchanged
Kovack Advisors, Inc.1,280$569.9K0.06%+24+1.9%Added
Angeles Wealth Management, LLC1,284$571.6K0.04%+29+2.3%Added