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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,564
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
619 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Motco28$12.8K0.00%−101−78.3%Reduced
Lummis Asset Management, LP29$12.9K0.01%00.0%Unchanged
Avion Wealth31$13.0K0.00%+2+6.9%Added
Dunhill Financial, LLC29$13.2K0.00%−8−21.6%Reduced
FWL Investment Management, LLC30$13.4K0.00%−15−33.3%Reduced
Innovative Advisory Group, LLC30$13.4K0.01%00.0%Unchanged
Chesapeake Asset Management LLC30$13.4K0.01%+28+1,400.0%Added
GFG Capital, LLC31$13.8K0.00%+31New
Colonial Trust Co32$14.2K0.00%+13+68.4%Added
Orion Capital Management LLC32$14.2K0.01%00.0%Unchanged
Essential Partners LLC32$14.2K0.01%+32New
Armstrong Advisory Group, Inc32$14.2K0.00%−24−42.9%Reduced
North Capital, Inc.34$15.1K0.01%00.0%Unchanged
Cedar Mountain Advisors, LLC35$15.6K0.00%00.0%Unchanged
Bellwether Advisors, LLC37$16.5K0.00%00.0%Unchanged
VSM Wealth Advisory, LLC38$16.9K0.01%+38New
Trust Co39$17.4K0.00%00.0%Unchanged
Archer Investment Corp39$17.4K0.00%00.0%Unchanged
Evolution Wealth Management Inc.40$17.8K0.02%+40New
North Star Investment Management Corp.42$18.7K0.00%00.0%Unchanged
Private Wealth Management Group, LLC42$18.7K0.01%−1−2.3%Reduced
Highline Wealth Partners LLC43$19.1K0.01%+1+2.4%Added
Banque de Luxembourg S.A.40$19.4K0.01%00.0%Unchanged
Cape Investment Advisory, Inc.44$19.6K0.01%−3−6.4%Reduced
DT Investment Partners, LLC44$19.6K0.00%00.0%Unchanged
Scarborough Advisors, LLC44$19.6K0.00%+44New
Optimum Investment Advisors46$20.5K0.01%00.0%Unchanged
DAGCO, Inc.47$20.9K0.01%00.0%Unchanged
Capital Advisors, Ltd. LLC48$21.0K0.00%00.0%Unchanged
Quaker Wealth Management, LLC48$21.4K0.01%+48New
Raffa Wealth Management, LLC49$21.8K0.00%−4−7.5%Reduced
Center for Financial Planning, Inc.50$22.3K0.00%−17−25.4%Reduced
CBIZ Investment Advisory Services, LLC50$22.3K0.00%+37+284.6%Added
Indiana Trust & Investment Management CO50$22.3K0.01%+50New
Salomon & Ludwin, LLC49$22.4K0.00%+49New
West Oak Capital, LLC52$22.4K0.01%00.0%Unchanged
Bullock Wealth Management Group50$22.6K0.01%−58−53.7%Reduced
Aventura Private Wealth, LLC52$23.1K0.01%00.0%Unchanged
Heritage Wealth Advisors53$23.6K0.00%00.0%Unchanged
Bank of Jackson Hole Trust53$23.6K0.01%+53New
Ameriflex Group, Inc.54$23.9K0.01%+26+92.9%Added
Fortitude Family Office, LLC54$24.0K0.01%−23−29.9%Reduced
BFSG, LLC54$24.0K0.00%00.0%Unchanged
Riverview Trust Co55$24.5K0.03%−194−77.9%Reduced
Howard Hughes Medical Institute55$24.5K0.01%+55New
Meeder Asset Management Inc56$24.9K0.00%+9+19.1%Added
Financial Network Wealth Advisors LLC57$25.4K0.03%+7+14.0%Added
Financial Management Professionals, Inc.60$26.7K0.00%−28−31.8%Reduced
Access Investment Management LLC60$26.7K0.01%+60New
Canton Hathaway, LLC62$28.0K0.01%00.0%Unchanged
Pingora Partners LLC65$28.9K0.02%00.0%Unchanged
High Note Wealth, LLC66$29.4K0.01%00.0%Unchanged
Legacy Wealth Managment, LLC66$29.4K0.02%−1−1.5%Reduced
Legacy Investment Solutions, LLC66$29.4K0.02%+66New
Ogorek Anthony Joseph68$30.0K0.01%−2−2.9%Reduced
Valued Wealth Advisors LLC69$30.7K0.02%−1−1.4%Reduced
Estabrook Capital Management69$30.7K0.00%00.0%Unchanged
First Command Advisory Services, Inc.70$31.2K0.00%00.0%Unchanged
Abound Wealth Management72$31.9K0.01%−5−6.5%Reduced
Rational Advisors LLC72$32.1K0.00%+72New
Vega Investment Solutions73$32.5K0.01%−298−80.3%Reduced
Stone House Investment Management, LLC74$32.9K0.01%−25−25.3%Reduced
Founders Capital Management75$33.4K0.02%00.0%Unchanged
TD Capital Management LLC75$33.4K0.00%+73+3,650.0%Added
Total Investment Management Inc75$33.4K0.00%+75New
Prestige Wealth Management Group LLC77$34.3K0.01%00.0%Unchanged
South State Corp.78$34.7K0.00%−50−39.1%Reduced
American National Bank80$35.6K0.00%+67+515.4%Added
Binnacle Investments Inc82$36.5K0.02%−24−22.6%Reduced
Brown, Lisle/Cummings, Inc.82$36.5K0.01%00.0%Unchanged
SJS Investment Consulting Inc.83$37.0K0.01%−12−12.6%Reduced
Capital Analysts, LLC87$39.0K0.00%00.0%Unchanged
Wolff Wiese Magana LLC89$39.6K0.02%−42−32.1%Reduced
JFS Wealth Advisors, LLC89$39.6K0.00%−11−11.0%Reduced
SOA Wealth Advisors, LLC.89$39.6K0.01%−2−2.2%Reduced
Solstein Capital, LLC89$39.6K0.02%+89New
Concord Wealth Partners90$40.1K0.01%−3,459−97.5%Reduced
Itau Unibanco Holding S.A.91$40.5K0.00%−1−1.1%Reduced
Evermay Wealth Management LLC93$41.4K0.01%00.0%Unchanged
University of Texas/Texas Am Investment Managment Co95$42.3K0.01%00.0%Unchanged
Cornerstone Planning Group LLC115$43.1K0.01%−10−8.0%Reduced
PrairieView Partners, LLC100$44.0K0.00%00.0%Unchanged
Spirit of America Management Corp100$44.5K0.01%00.0%Unchanged
Future Financial Wealth Managment LLC100$44.5K0.03%00.0%Unchanged
MPWM Advisory Solutions, LLC100$44.5K0.03%00.0%Unchanged
GoalVest Advisory LLC100$44.5K0.01%+97+3,233.3%Added
Midwest Capital Advisors, LLC101$45.0K0.02%00.0%Unchanged
Capula Management Ltd103$45.9K0.00%−170−62.3%Reduced
Westside Investment Management, Inc.103$46.6K0.01%+73+243.3%Added
Sachetta, LLC105$46.7K0.02%−13−11.0%Reduced
GHP Investment Advisors, Inc.105$46.9K0.00%00.0%Unchanged
Vestor Capital, LLC970$48.0K0.00%+624+180.3%Added
City State Bank110$49.0K0.02%00.0%Unchanged
Atlas Capital Advisors LLC110$49.0K0.01%+110New
Kilter Group LLC112$49.9K0.02%+112New
NewSquare Capital LLC115$51.2K0.00%−12−9.4%Reduced
Bell Investment Advisors, Inc115$51.2K0.01%00.0%Unchanged
Transce3nd, LLC117$52.1K0.02%00.0%Unchanged
MTM Investment Management, LLC117$52.1K0.02%+117New
E Fund Management (Hong Kong) Co., Ltd.120$53.4K0.05%00.0%Unchanged