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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Banco Bilbao Vizcaya Argentaria, S.A.93,689$41.7M0.38%−4,532−4.6%Reduced
Resona Asset Management Co.,Ltd.96,449$42.9M0.21%+5,687+6.3%Added
Healthcare of Ontario Pension Plan Trust Fund98,561$43.9M0.09%−50,979−34.1%Reduced
Rockefeller Capital Management L.P.99,738$44.4M0.10%+8,774+9.6%Added
Guggenheim Capital LLC101,220$45.1M0.37%−783−0.8%Reduced
Stifel Financial Corp101,545$45.2M0.04%−5,446−5.1%Reduced
CI Private Wealth, LLC102,816$45.8M0.07%−3,734−3.5%Reduced
Capital Group Private Client Services, Inc.104,537$46.5M0.40%+78,905+307.8%Added
State of Tennessee, Treasury Department105,759$47.1M0.17%+7,410+7.5%Added
Public Employees Retirement System of Ohio106,055$47.2M0.16%−3,227−3.0%Reduced
Hardman Johnston Global Advisors LLC108,225$48.2M2.14%−9,855−8.3%Reduced
Storebrand Asset Management AS108,283$48.2M0.14%+7,163+7.1%Added
STRS Ohio112,758$50.2M0.19%+34,907+44.8%Added
Raiffeisen Bank International AG113,927$50.8M0.76%−17,682−13.4%Reduced
SG Americas Securities, LLC115,640$51.5M0.23%+93,367+419.2%Added
Allianz Asset Management GmbH116,197$51.7M0.07%−24,888−17.6%Reduced
Marshall Wace, LLP117,000$52.1M0.06%−21,000−15.2%Reduced
Toronto Dominion Bank118,626$52.8M0.11%+19,472+19.6%Added
Mariner, LLC119,123$53.0M0.08%+2,562+2.2%Added
Treasurer of the State of North Carolina120,134$53.5M0.17%+1,759+1.5%Added
Teacher Retirement System of Texas122,373$54.5M0.23%−4,451−3.5%Reduced
Capital International Ltd127,607$56.8M2.18%+15,061+13.4%Added
Man Group plc127,618$56.8M0.12%+112,434+740.5%Added
Allspring Global Investments Holdings, LLC126,540$57.2M0.10%+18,011+16.6%Added
Abn Amro Investment Solutions130,291$58.0M1.16%−7,351−5.3%Reduced
KBC Group NV132,665$59.1M0.16%+13,360+11.2%Added
ABN AMRO Bank N.V.133,072$59.6M0.78%+5,679+4.5%Added
Schroder Investment Management Group134,967$60.1M0.05%−14,420−9.7%Reduced
AQR Capital Management LLC141,536$62.2M0.05%−4,335−3.0%Reduced
Van Eck Associates Corp140,701$62.6M0.07%−990−0.7%Reduced
Lansforsakringar Fondforvaltning AB (publ)141,290$62.9M0.36%+4,979+3.7%Added
Asset Management One Co.,Ltd.141,561$63.0M0.20%−312−0.2%Reduced
State of Wisconsin Investment Board142,938$63.6M0.16%−9,739−6.4%Reduced
Colony Group, LLC143,109$63.7M0.14%−96−0.1%Reduced
Mirae Asset Global Investments Co., Ltd.144,588$64.4M0.22%+1,270+0.9%Added
Birch Hill Investment Advisors LLC148,314$66.0M2.93%+100.0%Added
Mitsubishi UFJ Trust & Banking Corp150,353$66.9M0.16%−11,545−7.1%Reduced
Westwood Holdings Group Inc.154,217$68.7M0.49%+80,249+108.5%Added
Provident Investment Management, Inc.158,707$70.7M6.04%+2,382+1.5%Added
Nomura Asset Management Co Ltd158,916$70.7M0.19%+5,621+3.7%Added
British Columbia Investment Management Corp166,450$74.1M0.43%+17,797+12.0%Added
Canada Pension Plan Investment Board167,408$74.5M0.06%+12,979+8.4%Added
AXA S.A.171,270$76.2M0.22%+10,477+6.5%Added
APG Asset Management N.V.201,952$76.6M0.23%−124,776−38.2%Reduced
Capital International Inc175,233$78.0M0.76%+44,008+33.5%Added
Squarepoint Ops LLC175,687$78.2M0.17%+168,792+2,448.0%Added
Candriam Luxembourg S.C.A.176,398$78.5M0.45%−21,889−11.0%Reduced
Skandinaviska Enskilda Banken AB (publ)176,604$78.6M0.34%−9,867−5.3%Reduced
Ensign Peak Advisors, Inc177,034$78.8M0.13%−57,687−24.6%Reduced
Adage Capital Partners GP, L.L.C.178,192$79.3M0.13%−311,475−63.6%Reduced
Prudential Financial Inc180,236$80.2M0.10%+11,381+6.7%Added
Bowen Hanes & Co Inc180,799$80.5M2.03%+1,890+1.1%Added
Congress Asset Management Co188,004$83.7M0.57%+428+0.2%Added
Aviva PLC192,660$85.8M0.18%+11,970+6.6%Added
Intermede Investment Partners Ltd193,915$86.3M2.66%−10,130−5.0%Reduced
Federated Hermes, Inc.193,959$86.4M0.16%+23,726+13.9%Added
Korea Investment CORP201,734$89.8M0.20%−19,446−8.8%Reduced
New York State Teachers Retirement System203,504$90.6M0.19%−1,386−0.7%Reduced
Connor, Clark & Lunn Investment Management Ltd.206,095$91.8M0.32%+190,842+1,251.2%Added
Danske Bank A/S206,746$92.0M0.23%+46,956+29.4%Added
Truist Financial Corp210,089$93.5M0.14%−13,881−6.2%Reduced
OrbiMed Advisors LLC210,287$93.6M2.35%+50,387+31.5%Added
Baillie Gifford & Co212,479$94.6M0.07%+78,014+58.0%Added
Handelsbanken Fonder AB214,293$95.4M0.34%+6,648+3.2%Added
Welch & Forbes LLC217,244$96.7M1.21%+9,605+4.6%Added
Mirae Asset Global ETFs Holdings Ltd.219,433$97.7M0.19%−17,792−7.5%Reduced
Capital International Sarl223,389$99.5M1.91%+37,218+20.0%Added
Davenport & Co LLC226,184$100.5M0.56%+874+0.4%Added
Carmignac Gestion227,296$101.2M1.56%+100,342+79.0%Added
Macquarie Group Ltd228,853$101.9M0.13%−5,283−2.3%Reduced
Manning & Napier Advisors LLC233,580$104.0M1.24%−1,528−0.6%Reduced
National Bank of Canada240,378$107.0M0.12%+99,751+70.9%Added
LPL Financial LLC240,616$107.1M0.04%+23,672+10.9%Added
Assenagon Asset Management S.A.242,754$108.1M0.17%+34,614+16.6%Added
Tredje AP-fonden250,602$111.6M0.89%+209,112+504.0%Added
State Board of Administration of Florida Retirement System251,011$111.8M0.20%+2,302+0.9%Added
Swedbank AB254,347$113.2M0.13%+254,347New
Cerity Partners LLC263,692$117.4M0.21%+10,768+4.3%Added
Great West Life Assurance Co270,712$120.7M0.19%−120.0%Reduced
Royal London Asset Management Ltd283,345$126.1M0.29%−52,297−15.6%Reduced
First Trust Advisors LP287,892$128.2M0.10%+143,084+98.8%Added
Standard Life Aberdeen plc287,967$128.2M0.22%−16,747−5.5%Reduced
SEI Investments Co297,403$132.4M0.15%+3,621+1.2%Added
Russell Investments Group, Ltd.313,722$139.6M0.18%−23,725−7.0%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH313,681$139.7M0.25%+7,220+2.4%Added
B. Metzler seel. Sohn & Co. AG319,621$142.3M1.36%+5,278+1.7%Added
Robeco Institutional Asset Management B.V.329,391$146.6M0.24%+183,391+125.6%Added
New York State Common Retirement Fund340,272$151.5M0.20%−5,524−1.6%Reduced
Bank of Montreal363,035$161.6M0.08%−50,652−12.2%Reduced
Bank Julius Baer & Co. Ltd, Zurich391,376$174.2M0.52%−6,655−1.7%Reduced
Public Employees Retirement Association of Colorado392,543$174.8M0.67%−25,577−6.1%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)394,371$175.6M0.43%+9,661+2.5%Added
California State Teachers Retirement System397,640$177.0M0.20%−843−0.2%Reduced
ProShare Advisors LLC401,244$178.6M0.36%+18,214+4.8%Added
Principal Financial Group Inc409,805$182.4M0.10%−4,566−1.1%Reduced
Chevy Chase Trust Holdings, Inc.440,927$196.3M0.57%−2,121−0.5%Reduced
Bellevue Group AG441,610$196.6M4.33%+28,539+6.9%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.444,459$197.8M0.48%+52,446+13.4%Added
Envestnet Asset Management Inc448,988$199.9M0.06%−21,340−4.5%Reduced
Rhumbline Advisers454,372$202.3M0.17%+3,341+0.7%Added