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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Vident Advisory, LLC18,500$8.24M0.09%+2,422+15.1%Added
Mercer Global Advisors Inc18,523$8.25M0.02%+3,462+23.0%Added
Bridger Management, LLC18,778$8.36M4.93%−22,272−54.3%Reduced
QRG Capital Management, Inc.19,036$8.47M0.07%+1,643+9.4%Added
Telos Capital Management, Inc.19,242$8.57M0.87%+1,068+5.9%Added
Kennedy Capital Management, Inc.19,410$8.64M0.21%−1,047−5.1%Reduced
Prudential PLC19,525$8.69M0.05%−542−2.7%Reduced
Heirloom Wealth Management19,633$8.74M2.31%+80+0.4%Added
Anderson Hoagland & Co19,647$8.75M0.83%−176−0.9%Reduced
Public Sector Pension Investment Board19,674$8.76M0.04%−15,435−44.0%Reduced
First Horizon Advisors, Inc.19,719$8.78M0.23%+404+2.1%Added
Freemont Management S.A.20,000$8.90M1.47%+14,200+244.8%Added
D. E. Shaw & Co., Inc.20,081$8.94M0.01%−51,852−72.1%Reduced
Warren Averett Asset Management, LLC20,145$8.97M0.10%+309+1.6%Added
Sterling Capital Management LLC20,444$9.10M0.13%+8,070+65.2%Added
Camden National Bank20,462$9.11M1.31%−204−1.0%Reduced
AIMZ Investment Advisors, LLC20,726$9.23M3.09%−225−1.1%Reduced
Azimuth Capital Investment Management LLC21,032$9.36M0.35%−211−1.0%Reduced
FIL Ltd21,114$9.40M0.01%−72,294−77.4%Reduced
Gotham Asset Management, LLC21,356$9.51M0.06%−6,421−23.1%Reduced
Oppenheimer Asset Management Inc.21,488$9.57M0.11%−206−0.9%Reduced
Norinchukin Bank, The21,936$9.77M0.15%+1,859+9.3%Added
Churchill Management Corp21,996$9.79M0.11%−4,392−16.6%Reduced
Oregon Public Employees Retirement Fund22,184$9.88M0.17%+100+0.5%Added
Steel Peak Wealth Management LLC22,594$10.1M0.39%+22,594New
William Blair Investment Management, LLC22,608$10.1M0.03%−56,724−71.5%Reduced
EULAV Asset Management22,700$10.1M0.24%−5,800−20.4%Reduced
GW Henssler & Associates Ltd22,763$10.1M0.54%−48−0.2%Reduced
Galvin, Gaustad & Stein, LLC22,890$10.2M0.88%+1,529+7.2%Added
Modera Wealth Management, LLC23,105$10.3M0.13%−868−3.6%Reduced
Somerville Kurt F23,186$10.3M1.74%+310+1.4%Added
Verition Fund Management LLC23,242$10.3M0.06%+9,990+75.4%Added
Tower Research Capital LLC (TRC)23,478$10.5M0.28%+10,362+79.0%Added
Atria Investments LLC23,501$10.5M0.12%+219+0.9%Added
Cary Street Partners Financial LLC23,509$10.5M0.29%−197−0.8%Reduced
Allianz SE23,935$10.7M0.25%−12−0.1%Reduced
ARK Investment Management LLCSuperinvestorARK Invest24,063$10.7M0.08%−2,281−8.7%Reduced
Fifth Third Bancorp24,224$10.8M0.04%−1,585−6.1%Reduced
HealthInvest Partners AB24,328$10.8M4.64%+1,520+6.7%Added
Nordea Investment Management AB24,512$10.9M0.01%+1,057+4.5%Added
Biondo Investment Advisors, LLC24,929$11.1M1.46%−220−0.9%Reduced
Dai-Ichi Life Insurance Company, Ltd25,036$11.1M0.31%−5,965−19.2%Reduced
Advisors Asset Management, Inc.25,085$11.2M0.20%−2,659−9.6%Reduced
Pinnacle Associates Ltd25,108$11.2M0.16%+210+0.8%Added
Wiley Bros.-Aintree Capital, LLC25,140$11.2M0.09%+11,187+80.2%Added
Bogart Wealth, LLC25,407$11.3M0.48%+6,240+32.6%Added
Avanza Fonder AB25,425$11.3M0.34%+1,405+5.8%Added
Fisher Asset Management, LLC25,755$11.5M0.00%−4,914−16.0%Reduced
Blair William & Co26,077$11.6M0.03%−768−2.9%Reduced
Yousif Capital Management, LLC26,117$11.6M0.13%−304−1.2%Reduced
Fagan Associates, Inc.26,195$11.7M1.80%−90−0.3%Reduced
ASR Vermogensbeheer N.V.26,419$11.8M0.15%−103−0.4%Reduced
Bender Robert & Associates26,712$11.9M2.65%−313−1.2%Reduced
Massmutual Trust Co FSB26,791$11.9M0.32%+9,775+57.4%Added
Liontrust Investment Partners LLP26,954$12.0M0.17%+12,911+91.9%Added
Foster Victor Wealth Advisors, LLC25,364$12.1M0.82%+2,440+10.6%Added
Profund Advisors LLC27,353$12.2M0.44%+2,682+10.9%Added
Capital Group Investment Management Pte. Ltd.27,499$12.2M2.18%+3,647+15.3%Added
Shelter Mutual Insurance Co27,600$12.3M2.85%00.0%Unchanged
OP Asset Management Ltd27,777$12.4M0.18%+347+1.3%Added
Citadel Advisors LLC28,827$12.8M0.01%+23,808+474.4%Added
Washington Trust Bank29,243$13.0M1.10%+943+3.3%Added
F/M Investments LLC29,298$13.0M0.47%+50.0%Added
Mutual of America Capital Management LLC29,406$13.1M0.14%−2,069−6.6%Reduced
CCM Investment Advisers LLC29,615$13.2M1.42%+2,062+7.5%Added
Apollon Wealth Management, LLC29,757$13.2M0.26%+4,630+18.4%Added
LVM Capital Management Ltd30,070$13.4M1.39%+157+0.5%Added
McRae Capital Management Inc30,453$13.6M2.78%+125+0.4%Added
PEAK6 LLC30,456$13.6M0.46%+14,990+96.9%Added
CIBC World Markets Inc.30,794$13.7M0.03%+16,309+112.6%Added
Natixis30,961$13.8M0.07%−24,473−44.1%Reduced
Vestcor Inc31,488$14.0M0.42%−653−2.0%Reduced
Atalanta Sosnoff Capital, LLC31,756$14.1M0.29%−11,939−27.3%Reduced
Kovitz Investment Group Partners, LLC32,043$14.3M0.06%+23,574+278.4%Added
Louisiana State Employees Retirement System32,300$14.4M0.26%−300−0.9%Reduced
Sig Brokerage, LP32,566$14.5M3.98%+31,446+2,807.7%Added
Citizens Financial Group Inc32,918$14.7M0.24%+10,108+44.3%Added
Meritage Portfolio Management32,943$14.7M0.93%−1,934−5.5%Reduced
Los Angeles Capital Management LLC33,014$14.7M0.06%+7,291+28.3%Added
Elo Mutual Pension Insurance Co33,292$14.8M0.30%+161+0.5%Added
Huntington National Bank33,412$14.9M0.10%−2,356−6.6%Reduced
US Bancorp33,583$15.0M0.02%+1,324+4.1%Added
O'Shaughnessy Asset Management, LLC34,259$15.3M0.10%−1,341−3.8%Reduced
Bridgewater Associates, LP34,390$15.3M0.06%+34,390New
Jefferies Financial Group Inc.34,615$15.4M0.25%+15,131+77.7%Added
Adams Diversified Equity Fund, Inc.35,100$15.6M0.56%00.0%Unchanged
iA Global Asset Management Inc.35,157$15.7M0.24%−167−0.5%Reduced
Mackenzie Financial Corp36,275$16.1M0.02%+209+0.6%Added
Sapient Capital LLC36,310$16.2M0.29%+314+0.9%Added
Pathstone Holdings, LLC36,433$16.2M0.06%−1,441−3.8%Reduced
Cornerstone Advisors, LLC36,600$16.3M0.56%+23,600+181.5%Added
MML Investors Services, LLC36,607$16.3M0.05%−4,448−10.8%Reduced
Varma Mutual Pension Insurance Co36,626$16.3M0.12%−1,000−2.7%Reduced
Tweedy, Browne Co LLC37,253$16.6M1.54%−1,063−2.8%Reduced
Flputnam Investment Management Co37,741$16.8M0.29%+1,245+3.4%Added
Gradient Investments LLC38,013$16.9M0.31%+38,013New
Bailard, Inc.38,147$17.0M0.40%+200+0.5%Added
JustInvest LLC38,491$17.1M0.19%+2,729+7.6%Added
New York Life Investment Management LLC38,900$17.3M0.16%+294+0.8%Added
Congress Wealth Management LLC38,915$17.3M0.17%+4,801+14.1%Added