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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Cookson Peirce & Co Inc1,719$833.4K0.04%−146,061−98.8%Reduced
Alpha Family Trust1,720$833.9K0.49%+235+15.8%Added
Great Lakes Retirement, Inc.1,729$838.3K0.11%+1,729New
Strategic Investment Advisors1,735$841.1K0.09%−51−2.9%Reduced
Portfolio Design Labs, LLC1,736$841.6K0.17%−5,390−75.6%Reduced
KRS Capital Management, LLC1,737$842.1K0.67%−15−0.9%Reduced
Montecito Bank & Trust1,752$849.4K0.15%+93+5.6%Added
J.W. Cole Advisors, Inc.1,753$849.9K0.03%+1,044+147.2%Added
Fortis Capital Advisors, LLC1,754$850.4K0.17%+1,754New
Resources Investment Advisors, LLC.1,755$851.1K0.01%−945−35.0%Reduced
Brookwood Investment Group LLC1,768$857.2K0.15%+1,768New
Peapack Gladstone Financial Corp1,777$861.0K0.01%−408−18.7%Reduced
We Are One Seven, LLC1,779$862.5K0.03%−3,963−69.0%Reduced
Optas, LLC1,782$864.0K0.15%+908+103.9%Added
Commerzbank Aktiengesellschaft1,781$864.0K0.02%00.0%Unchanged
Pitcairn Co1,785$865.4K0.05%−99−5.3%Reduced
Breakwater Capital Group1,786$865.9K0.15%+27+1.5%Added
CX Institutional1,787$866.0K0.03%+148+9.0%Added
Norden Group LLC1,788$866.9K0.10%−60−3.2%Reduced
Malaga Cove Capital, LLC1,789$867.3K0.37%−200−10.1%Reduced
BOK Financial Private Wealth, Inc.1,789$867.3K0.07%−194−9.8%Reduced
Premier Path Wealth Partners, LLC1,790$868.0K0.14%+104+6.2%Added
Alta Wealth Advisors LLC1,792$868.8K0.40%−40−2.2%Reduced
Appleton Partners Inc1,793$869.0K0.07%−15−0.8%Reduced
1248 Management, LLC1,795$870.3K0.37%−270−13.1%Reduced
Moloney Securities Asset Management, LLC1,798$871.7K0.12%+65+3.8%Added
PKO Investment Management Joint-Stock Co1,800$872.7K0.10%−5,800−76.3%Reduced
Lighthouse Investment Partners, LLC1,800$872.7K0.04%+1,800New
Regal Investment Advisors LLC1,805$874.9K0.07%+4+0.2%Added
Acima Private Wealth, LLC1,806$875.6K0.31%00.0%Unchanged
PFG Investments, LLC1,812$878.5K0.06%−5−0.3%Reduced
Fukoku Mutual Life Insurance Co1,815$879.9K0.07%−40−2.2%Reduced
Clarius Group, LLC1,818$881.4K0.06%+440+31.9%Added
Geneos Wealth Management Inc.1,827$885.8K0.03%+374+25.7%Added
Oak Ridge Investments LLC1,833$888.7K0.07%−75−3.9%Reduced
Fifth Third Wealth Advisors LLC1,834$889.2K0.05%+607+49.5%Added
Checchi Capital Advisers, LLC1,835$889.6K0.06%+31+1.7%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management1,837$890.6K0.02%+1,146+165.8%Added
Wrapmanager Inc1,843$893.5K0.23%−205−10.0%Reduced
Legal Advantage Investments, Inc.1,848$895.9K0.48%+18+1.0%Added
Aviso Financial Inc.1,850$896.9K0.04%+647+53.8%Added
Badgley Phelps Wealth Managers, LLC1,865$904.2K0.02%−2−0.1%Reduced
Capital Advisors Wealth Management, LLC1,868$905.6K0.16%−235−11.2%Reduced
Groesbeck Investment Management Corp1,869$906.0K1.27%00.0%Unchanged
Goelzer Investment Management, Inc.1,893$917.8K0.05%−22−1.1%Reduced
Spears Abacus Advisors LLC1,909$925.5K0.02%−32−1.6%Reduced
MAI Capital Management1,918$930.0K0.01%+22+1.2%Added
Whittier Trust Co1,924$932.8K0.01%−121−5.9%Reduced
Schmidt P J Investment Management Inc1,932$936.7K0.17%+41+2.2%Added
Mattern Capital Management, LLC1,936$938.6K0.12%+63+3.4%Added
Annis Gardner Whiting Capital Advisors, LLC1,939$940.1K0.40%−5−0.3%Reduced
Howland Capital Management LLC1,975$957.5K0.04%+250+14.5%Added
Allworth Financial LP1,946$958.3K0.01%+205+11.8%Added
Holt Capital Advisors, L.L.C. dba Holt Capital Partners, L.P.1,977$958.5K0.15%+9+0.5%Added
IFG Advisory, LLC1,982$960.9K0.05%00.0%Unchanged
Pflug Koory, LLC1,994$966.7K0.54%−24−1.2%Reduced
Humankind Investments LLC1,995$967.2K0.25%−72−3.5%Reduced
Allegheny Financial Group LTD2,000$969.6K0.25%−19−0.9%Reduced
Monetta Financial Services Inc2,000$969.6K0.86%00.0%Unchanged
Mystic Asset Management, Inc.2,000$969.6K0.26%+2,000New
Qtron Investments LLC2,016$977.4K0.15%00.0%Unchanged
Channel Wealth LLC2,044$991.0K0.31%+266+15.0%Added
Prossimo Advisors, LLC2,055$996.0K0.75%+6+0.3%Added
GTS Securities LLC2,066$1.00M0.04%−1,263−37.9%Reduced
Towarzystwo Funduszy Inwestycyjnych Pzu SA2,069$1.00M0.34%−516−20.0%Reduced
Koa Wealth Management, LLC2,072$1.00M0.81%+2,072New
Proficio Capital Partners LLC2,079$1.01M0.08%+1,101+112.6%Added
Bradley Foster & Sargent Inc2,092$1.01M0.02%+304+17.0%Added
Forum Financial Management, LP2,094$1.02M0.02%+246+13.3%Added
Hohimer Wealth Management, LLC2,097$1.02M0.20%−195−8.5%Reduced
Formidable Asset Management, LLC2,101$1.02M0.17%+14+0.7%Added
Evercore Wealth Management, LLC2,101$1.02M0.02%+278+15.2%Added
Veracity Capital LLC2,102$1.02M0.40%+83+4.1%Added
Presilium Private Wealth, LLC2,124$1.03M0.23%00.0%Unchanged
Mitchell & Pahl Private Wealth, LLC2,149$1.04M0.49%00.0%Unchanged
Equitable Holdings, Inc.2,152$1.04M0.01%+415+23.9%Added
Aureus Asset Management, LLC2,153$1.04M0.07%−33−1.5%Reduced
Integrated Advisors Network LLC2,156$1.05M0.05%−924−30.0%Reduced
Thurston, Springer, Miller, Herd & Titak, Inc.2,174$1.05M0.18%+405+22.9%Added
Cravens & Co Advisors, LLC2,178$1.06M0.82%+16+0.7%Added
Savant Capital, LLC2,188$1.06M0.01%−4,462−67.1%Reduced
Advisors Preferred, LLC2,200$1.07M0.14%+2,200New
My Legacy Advisors, LLC2,200$1.07M0.41%+49+2.3%Added
Csenge Advisory Group2,181$1.07M0.06%+37+1.7%Added
Everhart Financial Group, Inc.2,209$1.07M0.15%+553+33.4%Added
Bristlecone Advisors, LLC2,250$1.09M0.09%+100+4.7%Added
Balyasny Asset Management LLC2,264$1.10M0.00%−133,559−98.3%Reduced
Brookstone Capital Management2,264$1.10M0.02%−56−2.4%Reduced
Nelson, Van Denburg & Campbell Wealth Management Group, LLC2,302$1.12M0.04%−667−22.5%Reduced
Centaurus Financial, Inc.2,311$1.12M0.07%+316+15.8%Added
GraniteShares Advisors LLC2,314$1.12M0.71%−150−6.1%Reduced
Sigma Planning Corp2,314$1.12M0.04%−17−0.7%Reduced
Kane Investment Management, Inc.2,320$1.12M0.54%+99+4.5%Added
Legacy Bridge, LLC2,332$1.13M0.63%+2,121+1,005.2%Added
Principal Street Partners, LLC2,336$1.13M0.21%+78+3.5%Added
Independent Financial Group, LLC2,339$1.13M0.04%+694+42.2%Added
Ashton Thomas Private Wealth, LLC2,342$1.14M0.04%+255+12.2%Added
Guidance Capital, Inc2,275$1.14M0.35%+174+8.3%Added
U.S. Capital Wealth Advisors, LLC2,370$1.15M0.04%+93+4.1%Added
NVWM, LLC2,383$1.16M0.31%−10.0%Reduced