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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,618 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Natural Investments, LLC817$396.0K0.11%+187+29.7%Added
Opinicus Capital, Inc.819$397.1K0.35%+819New
Great Lakes Advisors, LLC823$399.0K0.00%+31+3.9%Added
Banque Transatlantique SA824$399.4K0.01%+212+34.6%Added
Pure Financial Advisors, Inc.829$402.1K0.01%+248+42.7%Added
Larson Financial Group LLC836$405.3K0.02%+350+72.0%Added
Ancora Advisors, LLC838$406.4K0.01%+31+3.8%Added
Tevis Investment Management1,010$406.7K0.30%00.0%Unchanged
Paloma Partners Management Co840$407.2K0.08%+840New
Blue Chip Partners, Inc.841$407.7K0.04%+841New
Lockerman Financial Group, Inc.848$411.1K0.62%−1−0.1%Reduced
Chicago Partners Investment Group LLC948$412.2K0.01%+141+17.5%Added
Moss Adams Wealth Advisors LLC863$418.5K0.04%+332+62.5%Added
Douglass Winthrop Advisors, LLC868$420.8K0.01%−50−5.4%Reduced
Founders Financial Alliance, LLC868$420.8K0.10%+868New
Pensionmark Financial Group, LLC874$423.8K0.01%+874New
Severin Investments, LLC879$426.2K0.43%+24+2.8%Added
Forza Wealth Management, LLC881$427.1K0.19%00.0%Unchanged
Parkside Financial Bank & Trust884$428.6K0.05%+17+2.0%Added
Soltis Investment Advisors LLC885$429.2K0.04%+123+16.1%Added
Arthur M. Cohen & Associates, LLC890$431.5K0.08%00.0%Unchanged
PUREfi Wealth, LLC894$433.4K0.43%+383+75.0%Added
Cozad Asset Management Inc900$436.3K0.04%00.0%Unchanged
Guardian Asset Advisors, LLC900$436.3K0.28%+105+13.2%Added
KPP Advisory Services LLC907$439.7K0.08%+907New
Putney Financial Group LLC915$443.6K0.47%−40−4.2%Reduced
Integrity Alliance, LLC.917$444.6K0.02%+917New
David Loasby937$445.5K0.04%+234+33.3%Added
Defined Wealth Management, LLC922$447.0K0.30%+7+0.8%Added
Maridea Wealth Management LLC933$452.3K0.15%+933New
YHB Investment Advisors, Inc.941$456.2K0.04%+100+11.9%Added
Modern Wealth Management, LLC946$458.4K0.01%+946New
TRUE Private Wealth Advisors946$458.5K0.06%+946New
Legacy Capital Wealth Partners, LLC950$460.6K0.11%+62+7.0%Added
Legacy Advisors, LLC951$461.1K0.05%+62+7.0%Added
Kraematon Investment Advisors, Inc955$463.1K0.47%−82−7.9%Reduced
Jacobi Capital Management LLC964$467.4K0.03%00.0%Unchanged
Private Trust Co NA965$467.9K0.05%+7+0.7%Added
New Century Financial Group, LLC967$468.8K0.54%+140+16.9%Added
Cable Hill Partners, LLC924$470.8K0.05%−101−9.9%Reduced
Orrstown Financial Services Inc977$473.7K0.11%+30+3.2%Added
AlphaCore Capital LLC979$474.7K0.04%+51+5.5%Added
Investment Management Corp992$480.8K0.43%+154+18.4%Added
Foundations Investment Advisors, LLC993$481.4K0.01%+149+17.7%Added
Davis Investment Partners, LLC972$481.9K0.21%00.0%Unchanged
Gibbs Wealth Management998$483.9K0.12%+412+70.3%Added
Koss-Olinger Consulting, LLC998$484.0K0.04%+998New
Schwartz Investment Counsel Inc1,000$484.8K0.02%00.0%Unchanged
NJ State Employees Deferred Compensation Plan1,000$484.8K0.06%00.0%Unchanged
17 Capital Partners, LLC1,000$484.8K0.31%+5+0.5%Added
Mitsubishi UFJ Asset Management (UK) Ltd.1,000$485.0K0.26%−1,500−60.0%Reduced
Stanley-Laman Group, Ltd.1,002$485.8K0.07%+1,002New
Klingenstein Fields & Co LP1,005$487.2K0.02%+5+0.5%Added
Total Clarity Wealth Management, Inc.1,212$488.1K0.16%−25−2.0%Reduced
Prosperity Wealth Management, Inc.1,010$489.7K0.23%+1,010New
Richardson Financial Services Inc.1,014$491.6K0.37%+40+4.1%Added
Capital Market Strategies LLC1,020$494.5K0.33%+20+2.0%Added
TFB Advisors LLC1,023$496.0K0.14%+19+1.9%Added
Cullen/Frost Bankers, Inc.1,027$497.9K0.01%+134+15.0%Added
Fullerton Fund Management Co Ltd.1,028$498.4K0.03%+1,028New
SRS Capital Advisors, Inc.1,028$498.4K0.03%−823−44.5%Reduced
Capital Investment Advisors, LLC1,032$500.4K0.01%+190+22.6%Added
Sunbelt Securities, Inc.1,035$501.8K0.04%00.0%Unchanged
GeoWealth Management, LLC1,043$505.7K0.02%−270−20.6%Reduced
Investment House LLC1,044$506.2K0.03%+99+10.5%Added
HMS Capital Management, LLC1,070$507.8K0.28%+473+79.2%Added
Baader Bank INC1,110$512.5K0.05%−1,366−55.2%Reduced
GPS Wealth Strategies Group, LLC1,069$518.3K0.07%−44−4.0%Reduced
Atlantic Union Bankshares Corp1,071$519.2K0.03%−232−17.8%Reduced
Drive Wealth Management, LLC1,073$520.0K0.12%−48−4.3%Reduced
Guardian Wealth Advisors, LLC1,076$521.4K0.04%+14+1.3%Added
Johnson Financial Group, Inc.1,084$525.5K0.03%−1,026−48.6%Reduced
Pinnacle Wealth Planning Services, Inc.1,086$526.5K0.08%+57+5.5%Added
Insigneo Advisory Services, LLC1,087$527.0K0.05%−173−13.7%Reduced
Souders Financial Advisors1,087$527.0K0.07%−60−5.2%Reduced
Interchange Capital Partners, LLC1,088$527.5K0.15%+52+5.0%Added
TrueWealth Advisors, LLC1,088$527.5K0.17%+51+4.9%Added
Invesco, LLC1,091$528.9K0.22%00.0%Unchanged
Keynote Financial Services LLC1,105$535.7K0.38%+20+1.8%Added
Ellevest, Inc.1,108$537.2K0.04%−546−33.0%Reduced
Driehaus Capital Management LLC1,108$537.2K0.01%−14−1.2%Reduced
D.B. Root & Company, LLC1,109$537.7K0.17%+242+27.9%Added
Fragasso Group Inc.1,111$538.6K0.04%−239−17.7%Reduced
Albion Financial Group1,113$539.6K0.04%−227−16.9%Reduced
First Affirmative Financial Network1,114$540.1K0.33%+125+12.6%Added
Gryphon Financial Partners LLC1,118$542.0K0.08%+64+6.1%Added
Sig Brokerage, LP1,120$543.0K0.16%−818−42.2%Reduced
Quotient Wealth Partners, LLC1,130$547.8K0.02%+149+15.2%Added
Davis R M Inc1,131$548.3K0.01%+86+8.2%Added
Williams Jones Wealth Management, LLC.1,134$549.8K0.01%00.0%Unchanged
LCM Capital Management Inc1,144$554.6K0.33%+71+6.6%Added
Ramiah Investment Group1,147$556.1K0.53%+96+9.1%Added
Willner & Heller, LLC1,156$560.5K0.52%−55−4.5%Reduced
Bridgewater Advisors Inc.1,113$560.5K0.05%+1,113New
PDS Planning, Inc1,158$561.4K0.05%+334+40.5%Added
Personal Cfo Solutions, LLC1,159$561.9K0.11%+92+8.6%Added
AE Wealth Management LLC1,164$564.3K0.00%−1−0.1%Reduced
SGL Investment Advisors, Inc.1,323$568.4K0.29%−10−0.8%Reduced
Moneta Group Investment Advisors LLC1,172$568.4K0.01%+112+10.6%Added
Evoke Wealth, LLC1,173$568.7K0.01%+102+9.5%Added