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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Provident Investment Management, Inc.156,325$75.8M7.14%+1,259+0.8%Added
Danske Bank A/S159,790$77.5M0.24%−2,513−1.5%Reduced
OrbiMed Advisors LLC159,900$77.5M1.86%+8,900+5.9%Added
AXA S.A.160,793$78.0M0.26%+20,003+14.2%Added
Mitsubishi UFJ Trust & Banking Corp161,898$78.5M0.20%−9,708−5.7%Reduced
Prudential Financial Inc168,855$81.9M0.12%+717+0.4%Added
Federated Hermes, Inc.170,233$82.5M0.18%−18,842−10.0%Reduced
DnB Asset Management AS176,531$85.6M0.39%−24,411−12.1%Reduced
Bowen Hanes & Co Inc178,909$86.7M2.41%−1,715−0.9%Reduced
Aviva PLC180,690$87.6M0.21%+25,200+16.2%Added
Capital International Sarl186,171$90.3M2.04%+17,579+10.4%Added
Skandinaviska Enskilda Banken AB (publ)186,471$90.4M0.45%+15,437+9.0%Added
Congress Asset Management Co187,576$90.9M0.68%+40,427+27.5%Added
Candriam Luxembourg S.C.A.198,287$96.1M0.60%−60,335−23.3%Reduced
Intermede Investment Partners Ltd204,045$98.9M3.11%+204,045New
New York State Teachers Retirement System204,890$99.3M0.23%−16,362−7.4%Reduced
Welch & Forbes LLC207,639$100.7M1.32%+9,858+5.0%Added
Handelsbanken Fonder AB207,645$100.7M0.41%−88,391−29.9%Reduced
Assenagon Asset Management S.A.208,140$100.9M0.18%−631,532−75.2%Reduced
Zurich Insurance Group Ltd209,906$101.8M0.82%+158,379+307.4%Added
LPL Financial LLC216,944$105.2M0.04%+25,891+13.6%Added
Korea Investment CORP221,180$107.2M0.26%+14,072+6.8%Added
Truist Financial Corp223,970$108.6M0.17%+12,166+5.7%Added
Davenport & Co LLC225,310$109.6M0.65%+7,242+3.3%Added
Macquarie Group Ltd234,136$113.5M0.14%+4,203+1.8%Added
Ensign Peak Advisors, Inc234,721$113.8M0.22%−40,361−14.7%Reduced
Manning & Napier Advisors LLC235,108$114.0M1.41%+84,982+56.6%Added
Mirae Asset Global ETFs Holdings Ltd.237,225$115.0M0.24%+47,965+25.3%Added
State Board of Administration of Florida Retirement System248,709$120.6M0.24%+660+0.3%Added
Cerity Partners LLC252,924$122.6M0.25%+14,895+6.3%Added
Great West Life Assurance Co270,724$131.5M0.23%+846+0.3%Added
SEI Investments Co293,782$142.4M0.18%+18,647+6.8%Added
Victory Capital Management Inc293,885$142.5M0.15%−11,261−3.7%Reduced
APG Asset Management N.V.326,728$146.6M0.45%−32,557−9.1%Reduced
Standard Life Aberdeen plc304,714$146.8M0.29%−42,856−12.3%Reduced
Universal- Beteiligungs- und Servicegesellschaft mbH306,461$148.6M0.30%−33,047−9.7%Reduced
Millennium Management LLC309,935$150.3M0.15%−708−0.2%Reduced
B. Metzler seel. Sohn & Co. AG314,343$152.4M1.57%+233,584+289.2%Added
Royal London Asset Management Ltd335,642$162.7M0.39%−27,636−7.6%Reduced
Russell Investments Group, Ltd.337,447$163.7M0.22%+98,105+41.0%Added
New York State Common Retirement Fund345,796$167.6M0.25%−16,538−4.6%Reduced
ProShare Advisors LLC383,030$185.7M0.42%+38,504+11.2%Added
Zurcher Kantonalbank (Zurich Cantonalbank)384,710$186.5M0.54%+35,233+10.1%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.392,013$190.1M0.51%+2,356+0.6%Added
California State Teachers Retirement System398,483$193.2M0.24%−2,187−0.5%Reduced
Bank Julius Baer & Co. Ltd, Zurich398,031$193.6M0.63%+29,064+7.9%Added
Bellevue Group AG413,071$200.3M4.49%−74,363−15.3%Reduced
Bank of Montreal413,687$200.6M0.11%−167,494−28.8%Reduced
Principal Financial Group Inc414,371$200.9M0.11%+17,839+4.5%Added
Public Employees Retirement Association of Colorado418,120$202.7M0.86%−443−0.1%Reduced
Alyeska Investment Group, L.P.431,804$209.3M0.84%+354,269+456.9%Added
Neuberger Berman Group LLC442,628$214.6M0.18%+8,317+1.9%Added
Chevy Chase Trust Holdings, Inc.443,048$214.8M0.69%−1,653−0.4%Reduced
Rhumbline Advisers451,031$218.7M0.20%+8,670+2.0%Added
American Century Companies Inc465,741$225.8M0.14%−7,619−1.6%Reduced
Envestnet Asset Management Inc470,328$228.0M0.07%+47,630+11.3%Added
TD Asset Management Inc485,856$235.6M0.22%+16,788+3.6%Added
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.489,067$237.1M0.22%+50,976+11.6%Added
Adage Capital Partners GP, L.L.C.489,667$237.4M0.44%+280,428+134.0%Added
DekaBank Deutsche Girozentrale491,129$238.8M0.47%−15,328−3.0%Reduced
Raymond James Financial Inc510,542$247.5M0.09%+38,636+8.2%Added
Lazard Asset Management LLC532,597$258.2M0.40%+6,478+1.2%Added
Manufacturers Life Insurance Company, The546,904$265.1M0.25%+1,538+0.3%Added
National Pension Service558,929$271.0M0.26%+31,455+6.0%Added
BNP Paribas Arbitrage, SA588,337$285.2M0.22%−8,218−1.4%Reduced
Natixis Advisors, L.P.601,187$291.5M0.54%+43,543+7.8%Added
Dimensional Fund Advisors LP605,879$293.8M0.07%−21,638−3.4%Reduced
Citigroup Inc627,715$304.3M0.23%+165,647+35.8%Added
Sumitomo Mitsui Trust Holdings, Inc.643,987$312.2M0.22%−15,546−2.4%Reduced
Capital International Investors649,899$315.1M0.06%+307,387+89.7%Added
Pictet Asset Management Holding SA661,187$322.0M0.36%+141,519+27.2%Added
Harding Loevner LP698,459$338.6M2.59%−125,168−15.2%Reduced
Franklin Resources Inc702,034$340.4M0.10%−58,483−7.7%Reduced
Wells Fargo & Company706,169$342.4M0.08%+16,517+2.4%Added
Artisan Partners Limited Partnership719,131$348.6M0.57%+54,608+8.2%Added
Swiss National Bank726,200$352.1M0.25%−3,000−0.4%Reduced
UBS Group AG737,418$357.5M0.08%−125,618−14.6%Reduced
California Public Employees Retirement System809,234$392.3M0.27%−70,980−8.1%Reduced
Barclays PLC825,930$400.4M0.18%−17,145−2.0%Reduced
Voya Investment Management LLC827,138$400.7M0.45%+128,432+18.4%Added
HSBC Holdings PLC844,675$408.6M0.27%−29,080−3.3%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main960,854$465.8M0.54%−9,808−1.0%Reduced
Nuveen, LLC998,418$484.1M0.15%+998,418New
WCM Investment Management, LLC1,098,940$541.4M1.39%+7,418+0.7%Added
Renaissance Technologies LLC1,171,571$568.0M0.86%−225,638−16.1%Reduced
Royal Bank of Canada1,208,668$586.0M0.13%−242,291−16.7%Reduced
Deutsche Bank AG1,346,886$653.0M0.26%−42,719−3.1%Reduced
Clearbridge Investments, LLC1,679,171$814.1M0.71%−171,687−9.3%Reduced
Bank of New York Mellon Corp1,711,665$829.8M0.16%−47,551−2.7%Reduced
Charles Schwab Investment Management Inc1,725,281$836.5M0.16%+61,432+3.7%Added
Goldman Sachs Group Inc1,734,594$841.0M0.16%+332,860+23.7%Added
Parnassus Investments1,772,718$859.4M2.07%−43,232−2.4%Reduced
Invesco Ltd.1,845,640$894.8M0.17%−52,817−2.8%Reduced
Legal & General Group Plc1,894,169$918.3M0.25%+10,016+0.5%Added
Massachusetts Financial Services Co2,024,908$981.7M0.33%−263,590−11.5%Reduced
Ameriprise Financial Inc2,235,469$1.08B0.29%+219,946+10.9%Added
UBS Asset Management Americas Inc2,559,476$1.24B0.32%+230,257+9.9%Added
Northern Trust Corp2,619,392$1.27B0.19%−101,657−3.7%Reduced
Edgewood Management LLC2,644,026$1.28B4.46%−312,582−10.6%Reduced
Janus Henderson Group PLC2,747,937$1.35B0.74%−85,952−3.0%Reduced