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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
ASR Vermogensbeheer N.V.26,522$12.9M0.19%+26,522New
Blair William & Co26,845$13.0M0.04%+201+0.8%Added
Bender Robert & Associates27,025$13.1M3.31%−281−1.0%Reduced
OP Asset Management Ltd27,430$13.3M0.22%+27,430New
CCM Investment Advisers LLC27,553$13.4M1.64%+5,351+24.1%Added
Shelter Mutual Insurance Co27,600$13.4M3.23%00.0%Unchanged
Livforsakringsbolaget Skandia, Omsesidigt27,620$13.4M0.76%−200−0.7%Reduced
Alaska Permanent Fund Corp26,346$13.4M0.19%00.0%Unchanged
Bank of Nova Scotia27,688$13.4M0.03%−19,409−41.2%Reduced
Advisors Asset Management, Inc.27,744$13.5M0.25%+132+0.5%Added
Gotham Asset Management, LLC27,777$13.5M0.11%−2,334−7.8%Reduced
Washington Trust Bank28,300$13.7M1.37%−1,511−5.1%Reduced
EULAV Asset Management28,500$13.8M0.34%00.0%Unchanged
F/M Investments LLC29,293$14.2M0.57%−1,622−5.2%Reduced
Swiss Life Asset Management Ltd29,604$14.4M0.10%+3,938+15.3%Added
Factory Mutual Insurance Co29,900$14.5M0.17%00.0%Unchanged
LVM Capital Management Ltd29,913$14.5M1.61%−470−1.5%Reduced
CAPROCK Group, Inc.29,997$14.5M0.44%−9,187−23.4%Reduced
McRae Capital Management Inc30,328$14.7M3.10%−750−2.4%Reduced
Fisher Asset Management, LLC30,669$14.9M0.01%+761+2.5%Added
Pacer Advisors, Inc.30,696$14.9M0.04%−8,104−20.9%Reduced
Dai-Ichi Life Insurance Company, Ltd31,001$15.0M0.44%−923−2.9%Reduced
CIBC World Markets Corp31,007$15.0M0.12%−15,332−33.1%Reduced
Ci Investments Inc.31,014$15.0M0.06%−4,854−13.5%Reduced
Mutual of America Capital Management LLC31,475$15.3M0.18%−1,424−4.3%Reduced
Vestcor Inc32,141$15.6M0.52%−20,490−38.9%Reduced
Harvest Fund Management Co., Ltd34,935$15.6M0.77%+19,710+129.5%Added
US Bancorp32,259$15.6M0.02%+1,916+6.3%Added
Louisiana State Employees Retirement System32,600$15.8M0.31%−100−0.3%Reduced
Motley Fool Wealth Management, LLC33,049$16.0M0.95%−3,412−9.4%Reduced
Elo Mutual Pension Insurance Co33,131$16.1M0.36%+9,576+40.7%Added
Ilmarinen Mutual Pension Insurance Co33,300$16.1M0.14%+5,000+17.7%Added
Rakuten Investment Management, Inc.32,871$16.2M0.07%+32,871New
Advisor Group Holdings, Inc.33,549$16.3M0.04%−15,754−32.0%Reduced
Congress Wealth Management LLC34,114$16.6M0.20%+7,021+25.9%Added
AIA Group Ltd34,229$16.6M0.41%+4,314+14.4%Added
Lido Advisors, LLC34,232$16.6M0.10%+2,626+8.3%Added
Qube Research & Technologies Ltd34,546$16.7M0.03%+34,546New
Meritage Portfolio Management34,877$16.9M1.12%−862−2.4%Reduced
Adams Diversified Equity Fund, Inc.35,100$17.0M0.68%00.0%Unchanged
Public Sector Pension Investment Board35,109$17.0M0.07%+2,707+8.4%Added
iA Global Asset Management Inc.35,324$17.1M0.29%−5,538−13.6%Reduced
O'Shaughnessy Asset Management, LLC35,600$17.3M0.14%+6,446+22.1%Added
JustInvest LLC35,762$17.3M0.26%+4,584+14.7%Added
Huntington National Bank35,768$17.3M0.13%−2,618−6.8%Reduced
Sapient Capital LLC35,996$17.5M0.34%+200+0.6%Added
Mackenzie Financial Corp36,066$17.5M0.02%−9,566−21.0%Reduced
Flputnam Investment Management Co36,496$17.7M0.33%+5,053+16.1%Added
Varma Mutual Pension Insurance Co37,626$18.2M0.16%−9,200−19.6%Reduced
Police & Firemen's Retirement System of New Jersey37,642$18.2M0.18%+60.0%Added
Pathstone Holdings, LLC37,874$18.4M0.08%+521+1.4%Added
Bailard, Inc.37,947$18.4M0.47%+532+1.4%Added
Tweedy, Browne Co LLC38,316$18.6M1.65%−2,315−5.7%Reduced
Quantinno Capital Management LP38,425$18.6M0.12%+14,349+59.6%Added
New York Life Investment Management LLC38,606$18.7M0.19%−454−1.2%Reduced
Burney Co38,805$18.8M0.68%+1,038+2.7%Added
Telemark Asset Management, LLC40,000$19.4M2.54%+40,000New
Steward Partners Investment Advisory, LLC41,033$19.9M0.18%+1,225+3.1%Added
Bridger Management, LLC41,050$19.9M9.89%00.0%Unchanged
MML Investors Services, LLC41,055$19.9M0.07%+4,836+13.4%Added
Susquehanna International Group, LLP41,121$19.9M0.03%−89,284−68.5%Reduced
Tredje AP-fonden41,490$20.1M0.19%−95,962−69.8%Reduced
Martingale Asset Management L P41,847$20.3M0.52%−9,360−18.3%Reduced
Utah Retirement Systems42,803$20.8M0.24%−100−0.2%Reduced
Virginia Retirement Systems Et Al43,500$21.1M0.16%+43,500New
Atalanta Sosnoff Capital, LLC43,695$21.2M0.51%−1,507−3.3%Reduced
W.G. Shaheen & Associates DBA Whitney & Co43,795$21.2M2.26%+549+1.3%Added
USS Investment Management Ltd44,391$21.5M0.16%−120.0%Reduced
Braun Stacey Associates Inc44,672$21.7M0.89%−778−1.7%Reduced
Smith Group Asset Management, LLC45,643$22.1M1.66%+2,010+4.6%Added
Calamos Advisors LLC45,753$22.2M0.10%+509+1.1%Added
Sanctuary Advisors, LLC45,867$22.2M0.16%+2,036+4.6%Added
Sumitomo Mitsui DS Asset Management Company, Ltd46,364$22.5M0.23%+695+1.5%Added
State of Alaska, Department of Revenue46,505$22.5M0.26%+720+1.6%Added
Cumberland Partners Ltd46,747$22.7M1.75%−579−1.2%Reduced
Wealthfront Advisers LLC46,932$22.8M0.06%+5,913+14.4%Added
Castleark Management LLC47,039$22.8M0.79%+554+1.2%Added
Aristotle Atlantic Partners, LLC47,986$23.3M0.79%−3,265−6.4%Reduced
IFM Investors Pty Ltd48,536$23.5M0.26%−195−0.4%Reduced
De Burlo Group Inc48,735$23.6M3.49%00.0%Unchanged
China Universal Asset Management Co., Ltd.48,866$23.7M2.20%−3,515−6.7%Reduced
Xponance, Inc.49,169$23.8M0.23%+662+1.4%Added
Hallmark Capital Management Inc49,484$24.0M1.82%−1,040−2.1%Reduced
Hudson Bay Capital Management LP49,841$24.2M0.15%+39,826+397.7%Added
Armistice Capital, LLC50,000$24.2M0.65%−174,016−77.7%Reduced
Illinois Municipal Retirement Fund50,590$24.5M0.36%+3,202+6.8%Added
Boston Common Asset Management, LLC50,963$24.7M0.75%+671+1.3%Added
Barlow Wealth Partners, Inc.50,093$24.7M3.25%+383+0.8%Added
NEOS Investment Management LLC51,322$24.9M0.47%+7,991+18.4%Added
Groupama Asset Managment51,933$25.6M0.51%+8,454+19.4%Added
Segall Bryant & Hamill, LLC52,822$25.6M0.39%−3,413−6.1%Reduced
Cullinan Associates Inc53,112$25.7M1.82%−50−0.1%Reduced
Reynders McVeigh Capital Management, LLC53,336$25.9M1.44%+1,082+2.1%Added
Shelton Capital Management53,351$25.9M0.62%−1,280−2.3%Reduced
La Banque Postale Asset Management SA53,541$26.0M0.40%−5,818−9.8%Reduced
HighTower Advisors, LLC53,625$26.0M0.04%+5,039+10.4%Added
Amalgamated Bank53,730$26.0M0.22%+726+1.4%Added
C WorldWide Group Holding A/S54,057$26.2M0.33%−13,500−20.0%Reduced
Hemenway Trust Co LLC54,324$26.3M2.14%+4,911+9.9%Added
Atwood & Palmer Inc54,984$26.7M1.85%−406−0.7%Reduced