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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Toronto Dominion Bank107,834$43.4M0.08%−26,368−19.6%Reduced
Capital International Ltd110,571$44.5M1.82%+10,966+11.0%Added
CI Private Wealth, LLC113,146$45.2M0.07%−16,119−12.5%Reduced
Hardman Johnston Global Advisors LLC114,664$46.2M1.91%−245−0.2%Reduced
Public Employees Retirement System of Ohio115,847$46.7M0.16%−6,126−5.0%Reduced
Treasurer of the State of North Carolina116,793$47.0M0.18%+520+0.4%Added
KBC Group NV119,429$48.1M0.13%+22,702+23.5%Added
Mirae Asset Global Investments Co., Ltd.119,549$48.4M0.20%+17,264+16.9%Added
Employees Retirement System of Texas121,600$49.0M0.42%+3,600+3.1%Added
Mariner, LLC122,417$49.3M0.08%−1,077−0.9%Reduced
ABN AMRO Bank N.V.124,052$49.5M0.67%+7,383+6.3%Added
Capital International Inc124,134$50.0M0.59%+13,781+12.5%Added
Stifel Financial Corp124,844$50.3M0.05%+30,512+32.3%Added
PFM Health Sciences, LP126,989$51.1M3.90%−21,863−14.7%Reduced
British Columbia Investment Management Corp127,324$51.3M0.31%+84,266+195.7%Added
Susquehanna International Group, LLP130,405$52.5M0.08%+84,357+183.2%Added
Raiffeisen Bank International AG133,898$53.5M0.81%+133,898New
Storebrand Asset Management AS135,051$54.4M0.17%−5,916−4.2%Reduced
Guggenheim Capital LLC135,695$54.6M0.45%−3,596−2.6%Reduced
Balyasny Asset Management LLC135,823$54.7M0.13%+81,351+149.3%Added
Asset Management One Co.,Ltd.135,283$55.3M0.19%+96+0.1%Added
Tredje AP-fonden137,452$55.4M0.50%+7,978+6.2%Added
Abn Amro Investment Solutions140,237$56.5M1.05%+130,033+1,274.3%Added
AXA S.A.140,790$56.7M0.17%−3,620−2.5%Reduced
Colony Group, LLC141,112$56.8M0.15%+18,187+14.8%Added
Caisse de Depot Et Placement du Quebec141,717$57.1M0.12%−230,252−61.9%Reduced
Lansforsakringar Fondforvaltning AB (publ)144,708$58.3M0.33%+144,708New
Congress Asset Management Co147,149$59.3M0.40%−41,431−22.0%Reduced
Cookson Peirce & Co Inc147,780$59.5M2.70%−7,301−4.7%Reduced
Woodline Partners LP149,418$60.2M0.41%+16,653+12.5%Added
Nomura Asset Management Co Ltd149,799$60.3M0.18%−5,095−3.3%Reduced
Baillie Gifford & Co149,838$60.3M0.05%+9,258+6.6%Added
Manning & Napier Advisors LLC150,126$60.5M0.69%−5,635−3.6%Reduced
OrbiMed Advisors LLC151,000$60.8M1.26%00.0%Unchanged
State of Wisconsin Investment Board152,240$61.3M0.16%−1,939−1.3%Reduced
National Bank of Canada154,800$62.3M0.08%−75,698−32.8%Reduced
Provident Investment Management, Inc.155,066$62.4M5.96%−439−0.3%Reduced
Aviva PLC155,490$62.6M0.16%+30,650+24.6%Added
Van Eck Associates Corp159,269$64.1M0.08%+7,841+5.2%Added
Citadel Advisors LLC162,181$65.3M0.06%+111,949+222.9%Added
Schroder Investment Management Group163,628$65.3M0.06%−42,151−20.5%Reduced
Danske Bank A/S162,303$65.4M0.20%−16,124−9.0%Reduced
Prudential Financial Inc168,138$67.7M0.09%−42,095−20.0%Reduced
Capital International Sarl168,592$67.9M1.57%+25,544+17.9%Added
Skandinaviska Enskilda Banken AB (publ)171,034$68.3M0.31%−14,251−7.7%Reduced
Mitsubishi UFJ Trust & Banking Corp171,606$69.1M0.16%−13,507−7.3%Reduced
Birch Hill Investment Advisors LLC172,821$69.6M3.24%+4,664+2.8%Added
Polar Capital Holdings Plc175,000$70.5M0.39%00.0%Unchanged
Bowen Hanes & Co Inc180,624$72.7M1.95%+1,740+1.0%Added
Vontobel Holding Ltd.188,949$76.1M0.26%+75,653+66.8%Added
Federated Hermes, Inc.189,075$76.1M0.17%−2,864−1.5%Reduced
Mirae Asset Global ETFs Holdings Ltd.189,260$76.2M0.16%+567+0.3%Added
LPL Financial LLC191,053$76.9M0.03%+1,340+0.7%Added
First Trust Advisors LP192,786$77.6M0.07%−382,246−66.5%Reduced
Marshall Wace, LLP194,000$78.1M0.10%−50,000−20.5%Reduced
Carmignac Gestion197,466$79.5M1.27%−13,056−6.2%Reduced
Welch & Forbes LLC197,781$79.6M1.02%+1,162+0.6%Added
DnB Asset Management AS200,942$80.9M0.35%+19,289+10.6%Added
Korea Investment CORP207,108$83.4M0.20%−14,438−6.5%Reduced
Adage Capital Partners GP, L.L.C.209,239$84.3M0.15%−137,116−39.6%Reduced
Truist Financial Corp211,804$85.3M0.13%+1,885+0.9%Added
Davenport & Co LLC218,068$87.6M0.51%−1,641−0.7%Reduced
AustralianSuper Pty Ltd219,075$88.2M0.42%−7,299−3.2%Reduced
Macquarie Group Ltd229,933$88.7M0.11%−96,583−29.6%Reduced
New York State Teachers Retirement System221,252$89.1M0.19%−10,729−4.6%Reduced
Armistice Capital, LLC224,016$90.2M2.10%+177,887+385.6%Added
Russell Investments Group, Ltd.239,342$96.3M0.13%+9,377+4.1%Added
Cerity Partners LLC238,029$97.5M0.21%+8,987+3.9%Added
AQR Capital Management LLC245,785$99.0M0.13%−235,076−48.9%Reduced
State Board of Administration of Florida Retirement System248,049$99.9M0.19%−13,526−5.2%Reduced
Allianz Asset Management GmbH255,623$102.9M0.15%−3,262−1.3%Reduced
Candriam Luxembourg S.C.A.258,622$104.1M0.60%−52,685−16.9%Reduced
D. E. Shaw & Co., Inc.265,684$107.0M0.12%+127,276+92.0%Added
Great West Life Assurance Co269,878$108.6M0.19%−48,403−15.2%Reduced
Ensign Peak Advisors, Inc275,082$110.8M0.20%+97,611+55.0%Added
SEI Investments Co275,135$110.8M0.14%+61,234+28.6%Added
Robeco Institutional Asset Management B.V.286,756$115.5M0.22%−9,812−3.3%Reduced
Handelsbanken Fonder AB296,036$119.2M0.46%−115,479−28.1%Reduced
Victory Capital Management Inc305,146$122.9M0.12%−5,268−1.7%Reduced
Millennium Management LLC310,643$125.1M0.11%+151,349+95.0%Added
Universal- Beteiligungs- und Servicegesellschaft mbH339,508$136.7M0.27%+339,508New
Nordea Investment Management AB342,429$137.8M0.14%+55,739+19.4%Added
Capital International Investors342,512$137.9M0.03%+342,512New
ProShare Advisors LLC344,526$138.7M0.32%+53,116+18.2%Added
Standard Life Aberdeen plc347,570$139.4M0.26%−23,519−6.3%Reduced
APG Asset Management N.V.359,285$139.7M0.39%+235,265+189.7%Added
Zurcher Kantonalbank (Zurich Cantonalbank)349,477$140.7M0.40%+29,333+9.2%Added
New York State Common Retirement Fund362,334$145.9M0.20%+2,855+0.8%Added
Royal London Asset Management Ltd363,278$146.3M0.36%+1480.0%Added
Canada Pension Plan Investment Board369,354$148.7M0.14%+85,350+30.1%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.389,657$156.9M0.39%−6,362−1.6%Reduced
Bank Julius Baer & Co. Ltd, Zurich368,967$159.0M0.49%+33,322+9.9%Added
Principal Financial Group Inc396,532$159.7M0.09%−13,827−3.4%Reduced
California State Teachers Retirement System400,670$161.3M0.19%−11,807−2.9%Reduced
Public Employees Retirement Association of Colorado418,563$168.6M0.67%−9,910−2.3%Reduced
Envestnet Asset Management Inc422,698$170.2M0.05%+19,630+4.9%Added
Neuberger Berman Group LLC434,311$174.9M0.14%+5,173+1.2%Added
Rhumbline Advisers442,361$178.1M0.16%−7,335−1.6%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.438,091$178.4M0.17%+32,739+8.1%Added
Chevy Chase Trust Holdings, Inc.444,701$179.1M0.55%−2,160−0.5%Reduced