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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Tower Research Capital LLC (TRC)20,680$8.33M0.17%+13,516+188.7%Added
Camden National Bank20,937$8.43M1.26%−187−0.9%Reduced
Connor, Clark & Lunn Investment Management Ltd.21,003$8.46M0.04%+13,172+168.2%Added
AIMZ Investment Advisors, LLC21,110$8.50M2.95%−150−0.7%Reduced
Railway Pension Investments Ltd21,600$8.70M0.12%−2,100−8.9%Reduced
Galvin, Gaustad & Stein, LLC21,728$8.75M0.78%−233−1.1%Reduced
Oregon Public Employees Retirement Fund22,074$8.89M0.16%−90.0%Reduced
Azimuth Capital Investment Management LLC22,141$8.92M0.35%+697+3.3%Added
Aptus Capital Advisors, LLC22,168$8.93M0.11%+3,452+18.4%Added
Anderson Hoagland & Co21,175$8.94M0.92%−87−0.4%Reduced
CCM Investment Advisers LLC22,202$8.94M0.99%−7,770−25.9%Reduced
TruWealth Advisors, LLC22,241$8.96M0.54%−556−2.4%Reduced
Bogart Wealth, LLC22,259$8.96M0.43%+3,031+15.8%Added
Citizens Financial Group Inc22,694$9.14M0.18%+577+2.6%Added
Longbow Finance SA22,699$9.14M1.00%+16,028+240.3%Added
ExodusPoint Capital Management, LP22,794$9.18M0.10%+22,794New
Generali Asset Management SPA SGR22,861$9.21M0.24%+22,861New
Natixis22,862$9.21M0.06%−13,865−37.8%Reduced
Ethic Inc.22,990$9.26M0.19%+3,197+16.2%Added
Elo Mutual Pension Insurance Co23,555$9.49M0.20%−970−4.0%Reduced
Capital Group Investment Management Pte. Ltd.23,581$9.50M1.80%+2,435+11.5%Added
Kennedy Capital Management, Inc.23,615$9.51M0.21%+10,084+74.5%Added
Allianz SE24,001$9.58M0.25%−2,088−8.0%Reduced
Cary Street Partners Financial LLC23,889$9.62M0.31%+23,889New
Quantinno Capital Management LP24,076$9.70M0.10%+4,381+22.2%Added
Mizuho Securities USA LLC24,408$9.83M0.18%+7,671+45.8%Added
Modera Wealth Management, LLC24,610$9.91M0.12%−383−1.5%Reduced
Intech Investment Management LLC24,650$9.93M0.10%+6,937+39.2%Added
Transform Wealth, LLC24,900$10.0M0.56%+891+3.7%Added
Capitolis Liquid Global Markets LLC25,000$10.1M0.10%00.0%Unchanged
Biondo Investment Advisors, LLC25,280$10.2M1.40%+185+0.7%Added
ARK Investment Management LLCSuperinvestorARK Invest25,350$10.2M0.09%−25,749−50.4%Reduced
Meiji Yasuda Life Insurance Co25,377$10.2M0.19%−2,204−8.0%Reduced
Prudential PLC25,518$10.3M0.05%−3,769−12.9%Reduced
Swiss Life Asset Management Ltd25,666$10.3M0.08%−1,847−6.7%Reduced
Foster Victor Wealth Advisors, LLC24,588$10.4M0.79%+3,062+14.2%Added
Fifth Third Bancorp26,103$10.5M0.04%−937−3.5%Reduced
Alaska Permanent Fund Corp26,346$10.6M0.16%00.0%Unchanged
Fagan Associates, Inc.26,518$10.7M1.70%+93+0.4%Added
Blair William & Co26,644$10.7M0.03%−64,672−70.8%Reduced
Yousif Capital Management, LLC27,085$10.9M0.12%−1,203−4.3%Reduced
Congress Wealth Management LLC27,093$10.9M0.15%−8,155−23.1%Reduced
Bender Robert & Associates27,306$11.0M2.65%+172+0.6%Added
Shelter Mutual Insurance Co27,600$11.1M2.77%00.0%Unchanged
Advisors Asset Management, Inc.27,612$11.1M0.20%+1,145+4.3%Added
Livforsakringsbolaget Skandia, Omsesidigt27,820$11.2M0.59%−1,100−3.8%Reduced
Northwest & Ethical Investments L.P.27,822$11.2M0.30%+1,182+4.4%Added
GW Henssler & Associates Ltd24,216$11.3M0.65%−257−1.1%Reduced
Avanza Fonder AB28,158$11.3M0.34%+28,158New
Ilmarinen Mutual Pension Insurance Co28,300$11.4M0.10%+8,800+45.1%Added
South Dakota Investment Council28,368$11.4M0.23%00.0%Unchanged
EULAV Asset Management28,500$11.5M0.28%−3,000−9.5%Reduced
Profund Advisors LLC28,574$11.5M0.42%+654+2.3%Added
O'Shaughnessy Asset Management, LLC29,154$11.7M0.10%+472+1.6%Added
Washington Trust Bank29,811$12.0M1.15%−1,460−4.7%Reduced
Factory Mutual Insurance Co29,900$12.0M0.13%00.0%Unchanged
Fisher Asset Management, LLC29,908$12.0M0.00%+2,886+10.7%Added
AIA Group Ltd29,915$12.0M0.29%−871−2.8%Reduced
Moran Wealth Management, LLC29,944$12.1M0.38%+866+3.0%Added
Gotham Asset Management, LLC30,111$12.1M0.12%+2,978+11.0%Added
US Bancorp30,343$12.2M0.02%+3,764+14.2%Added
LVM Capital Management Ltd30,383$12.2M1.32%+370+1.2%Added
Group One Trading, L.P.30,402$12.2M0.42%+6,079+25.0%Added
F/M Investments LLC30,915$12.4M0.46%−11,548−27.2%Reduced
McRae Capital Management Inc31,078$12.5M2.45%−802−2.5%Reduced
JustInvest LLC31,178$12.6M0.19%−619−1.9%Reduced
Flputnam Investment Management Co31,443$12.7M0.23%+22,141+238.0%Added
Lido Advisors, LLC31,606$12.7M0.08%+7,207+29.5%Added
Dai-Ichi Life Insurance Company, Ltd31,924$12.9M0.36%+5,831+22.3%Added
Public Sector Pension Investment Board32,402$13.0M0.06%+21,158+188.2%Added
Louisiana State Employees Retirement System32,700$13.2M0.25%−1,500−4.4%Reduced
Mutual of America Capital Management LLC32,899$13.2M0.14%−933−2.8%Reduced
Two Sigma Investments, LP33,160$13.4M0.03%−127,375−79.3%Reduced
Adams Diversified Equity Fund, Inc.35,100$14.1M0.53%00.0%Unchanged
Meritage Portfolio Management35,739$14.4M0.89%−773−2.1%Reduced
Sapient Capital LLC35,796$14.4M0.28%+498+1.4%Added
Ci Investments Inc.35,868$14.4M0.05%−18,058−33.5%Reduced
Andra AP-fonden36,100$14.5M0.23%−5,500−13.2%Reduced
MML Investors Services, LLC36,219$14.6M0.05%−11,858−24.7%Reduced
Motley Fool Wealth Management, LLC36,461$14.7M0.76%−3,032−7.7%Reduced
Pathstone Holdings, LLC37,353$15.0M0.07%−3,300−8.1%Reduced
Bailard, Inc.37,415$15.1M0.39%−1,102−2.9%Reduced
Advisor Group Holdings, Inc.49,303$15.2M0.03%−143−0.3%Reduced
Police & Firemen's Retirement System of New Jersey37,636$15.2M0.15%+37,636New
Burney Co37,767$15.2M0.54%−8,394−18.2%Reduced
Huntington National Bank38,386$15.5M0.11%−843−2.1%Reduced
Pacer Advisors, Inc.38,800$15.6M0.03%+6,359+19.6%Added
New York Life Investment Management LLC39,060$15.7M0.15%+383+1.0%Added
CAPROCK Group, Inc.39,184$15.8M0.52%+1,096+2.9%Added
Steward Partners Investment Advisory, LLC39,808$16.0M0.14%−4,948−11.1%Reduced
Tweedy, Browne Co LLC40,631$16.4M1.10%−12,969−24.2%Reduced
iA Global Asset Management Inc.40,862$16.5M0.29%−404−1.0%Reduced
Wealthfront Advisers LLC41,019$16.5M0.05%+1,819+4.6%Added
Bridger Management, LLC41,050$16.5M8.88%00.0%Unchanged
NewEdge Wealth, LLC41,447$16.7M0.29%+1,297+3.2%Added
Utah Retirement Systems42,903$17.3M0.19%+100+0.2%Added
Groupama Asset Managment43,479$17.4M0.35%+9,149+26.7%Added
W.G. Shaheen & Associates DBA Whitney & Co43,246$17.4M1.83%−160−0.4%Reduced
NEOS Investment Management LLC43,331$17.4M0.41%+7,732+21.7%Added
Smith Group Asset Management, LLC43,633$17.6M1.30%−26−0.1%Reduced