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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,224
+121 vs. Q3 2022
Shares held
237.1M
+549.4K (+0.2%) vs. Q3 2022
Total value
$68.3B
−$59.7M (−0.1%) vs. Q3 2022
New holders
185
438 more added
Sold out
64
440 more reduced

24 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 1,224 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2022: $68.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2022.

Institutions holding VRTX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Twinbeech Capital LP192,626$55.6M1.06%+192,626New
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.196,887$56.3M0.15%+18,898+10.6%Added
Schroder Investment Management Group199,861$57.7M0.09%+90,908+83.4%Added
Citadel Advisors LLC203,611$58.8M0.07%+189,846+1,379.2%Added
Birch Hill Investment Advisors LLC204,323$59.0M3.76%−6,173−2.9%Reduced
Hardman Johnston Global Advisors LLC206,727$59.7M2.34%−7,273−3.4%Reduced
FIL Ltd215,674$62.3M0.07%−34,019−13.6%Reduced
Chevy Chase Trust Holdings, Inc.216,029$62.4M0.27%+59,356+37.9%Added
Mitsubishi UFJ Trust & Banking Corp234,972$67.9M0.18%−8,809−3.6%Reduced
Parnassus Investments240,281$69.4M0.17%−21,686−8.3%Reduced
BNP Paribas Arbitrage, SA248,321$71.7M0.18%+60,914+32.5%Added
KBC Group NV254,327$73.4M0.36%+352+0.1%Added
ProShare Advisors LLC255,282$73.7M0.26%−26,430−9.4%Reduced
Virginia Retirement Systems Et Al270,200$78.0M0.81%−4,300−1.6%Reduced
OrbiMed Advisors LLC271,500$78.4M1.50%−101,700−27.3%Reduced
Manning & Napier Group, LLC271,904$78.5M0.97%−4,987−1.8%Reduced
Susquehanna International Group, LLP279,001$80.6M0.16%+232,658+502.0%Added
Canada Pension Plan Investment Board279,401$80.7M0.14%−1,326,453−82.6%Reduced
Great West Life Assurance Co278,324$80.7M0.21%−19,914−6.7%Reduced
Envestnet Asset Management Inc284,200$82.1M0.04%+14,768+5.5%Added
Polar Capital Holdings Plc290,000$83.7M0.67%−280−0.1%Reduced
Retirement Systems of Alabama294,834$85.1M0.37%−2,949−1.0%Reduced
Nomura Asset Management Co Ltd296,519$85.6M0.50%−22,660−7.1%Reduced
Nordea Investment Management AB299,360$85.9M0.13%+26,599+9.8%Added
Pendal Group Limited297,723$86.0M0.74%+425+0.1%Added
DnB Asset Management AS299,763$86.6M0.61%−16,219−5.1%Reduced
Neuberger Berman Group LLC301,101$87.0M0.09%+35,292+13.3%Added
Mirae Asset Global Investments Co., Ltd.305,822$88.3M0.23%−14,145−4.4%Reduced
State Board of Administration of Florida Retirement System308,815$89.2M0.22%−2,260−0.7%Reduced
New York State Teachers Retirement System310,010$89.5M0.22%−5,100−1.6%Reduced
Tekla Capital Management LLC330,343$95.4M3.60%+16,940+5.4%Added
Handelsbanken Fonder AB330,761$95.5M0.60%−26,056−7.3%Reduced
Principal Financial Group Inc331,124$95.6M0.07%−25,034−7.0%Reduced
Millennium Management LLC336,562$97.2M0.11%+333,024+9,412.8%Added
Epoch Investment Partners, Inc.337,199$97.4M0.58%−117,765−25.9%Reduced
AXA S.A.343,690$99.3M0.36%+66,193+23.9%Added
First Trust Advisors LP349,971$101.1M0.12%−10,921−3.0%Reduced
Korea Investment CORP358,271$103.5M0.33%+2,257+0.6%Added
Russell Investments Group, Ltd.369,505$106.7M0.22%+45,393+14.0%Added
Bank of Montreal368,001$107.2M0.08%+92,547+33.6%Added
Raymond James & Associates372,326$107.5M0.10%+8,596+2.4%Added
TD Asset Management Inc380,014$109.7M0.14%−59,581−13.6%Reduced
Lord, Abbett & Co. LLC383,987$110.9M0.40%−170,599−30.8%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)384,871$111.1M0.59%−9,688−2.5%Reduced
Assetmark, Inc401,712$116.0M0.50%+13,854+3.6%Added
Fred Alger Management, LLC404,865$116.9M0.63%−122,841−23.3%Reduced
Skandinaviska Enskilda Banken AB (publ)406,534$117.4M0.88%+54,823+15.6%Added
Marshall Wace, LLP410,021$118.4M0.31%+136,169+49.7%Added
National Pension Service416,092$120.2M0.24%+10,232+2.5%Added
APG Asset Management N.V.418,642$120.9M0.23%−102,647−19.7%Reduced
Rhumbline Advisers426,737$123.2M0.17%+18,554+4.5%Added
Ensign Peak Advisors, Inc427,380$123.4M0.28%+31,689+8.0%Added
Qube Research & Technologies Ltd427,529$123.5M0.74%+330,619+341.2%Added
DekaBank Deutsche Girozentrale433,645$124.9M0.33%+10,927+2.6%Added
California State Teachers Retirement System437,015$126.2M0.20%+6,996+1.6%Added
Los Angeles Capital Management LLC447,011$129.1M0.63%+12,485+2.9%Added
Public Employees Retirement Association of Colorado449,868$129.9M0.71%−2,850−0.6%Reduced
Allspring Global Investments Holdings, LLC452,570$130.7M0.22%−24,631−5.2%Reduced
Natixis Advisors, L.P.467,332$135.0M0.51%−41,088−8.1%Reduced
Candriam Luxembourg S.C.A.469,145$135.5M0.91%−15,394−3.2%Reduced
Robeco Institutional Asset Management B.V.471,957$136.3M0.39%+132,927+39.2%Added
New York State Common Retirement Fund472,718$136.5M0.19%+2,228+0.5%Added
Vaughan Nelson Investment Management, L.P.478,138$138.1M1.79%−26,123−5.2%Reduced
Citigroup Inc484,497$139.9M0.20%+1,256+0.3%Added
HSBC Holdings PLC488,590$140.8M0.18%+176,722+56.7%Added
Victory Capital Management Inc495,390$143.1M0.16%−28,134−5.4%Reduced
Credit Suisse AG552,596$159.6M0.17%−22,963−4.0%Reduced
Man Group plc576,398$166.5M0.60%+340,716+144.6%Added
AQR Capital Management LLC587,594$168.5M0.38%+93,063+18.8%Added
UBS Group AG605,562$174.9M0.08%+322,784+114.1%Added
Barclays PLC611,787$176.7M0.15%+198,887+48.2%Added
Jacobs Levy Equity Management, Inc635,992$183.7M1.24%+434,318+215.4%Added
Swedbank AB637,446$184.1M0.41%+4,932+0.8%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.672,827$194.3M0.70%+270,921+67.4%Added
Prudential Financial Inc680,486$196.5M0.33%−38,436−5.3%Reduced
Assenagon Asset Management S.A.738,987$213.4M0.88%+76,752+11.6%Added
Wells Fargo & Company748,927$216.3M0.07%−29,344−3.8%Reduced
Impax Asset Management Group plc764,011$220.2M0.99%+66,278+9.5%Added
Dimensional Fund Advisors LP780,502$225.4M0.08%−83,805−9.7%Reduced
Franklin Resources Inc791,975$228.7M0.12%−140,876−15.1%Reduced
Allianz Asset Management GmbH802,270$231.7M0.51%−78,484−8.9%Reduced
Manufacturers Life Insurance Company, The838,863$242.3M0.15%+86,980+11.6%Added
Sumitomo Mitsui Trust Holdings, Inc.854,908$246.9M0.20%−81,147−8.7%Reduced
Macquarie Group Ltd859,300$248.1M0.29%−38,008−4.2%Reduced
Caisse de Depot Et Placement du Quebec910,021$262.8M0.81%−175,199−16.1%Reduced
Nuveen Asset Management, LLC910,031$262.8M0.10%−424,810−31.8%Reduced
Royal Bank of Canada960,432$277.4M0.08%+37,192+4.0%Added
Pictet Asset Management SA975,012$281.6M0.41%+192,229+24.6%Added
Swiss National Bank1,042,400$301.0M0.22%−65,975−6.0%Reduced
Bellevue Group AG1,096,028$316.5M4.20%−62,098−5.4%Reduced
American Century Companies Inc1,131,015$326.6M0.27%−129,082−10.2%Reduced
Voya Investment Management LLC1,195,157$345.1M0.40%+246,336+26.0%Added
Janus Henderson Group PLC1,385,476$400.1M0.29%−116,059−7.7%Reduced
Charles Schwab Investment Management Inc1,416,028$408.9M0.13%+28,088+2.0%Added
California Public Employees Retirement System1,548,037$447.0M0.38%−251,831−14.0%Reduced
Invesco Ltd.1,624,899$469.2M0.14%+305,217+23.1%Added
Goldman Sachs Group Inc1,672,373$482.9M0.14%−48,374−2.8%Reduced
Harding Loevner LP1,840,521$531.5M3.06%+200,704+12.2%Added
Deutsche Bank AG1,853,082$535.1M0.31%+25,625+1.4%Added
Legal & General Group Plc2,033,364$587.2M0.23%−104,734−4.9%Reduced