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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,224
+121 vs. Q3 2022
Shares held
237.1M
+549.4K (+0.2%) vs. Q3 2022
Total value
$68.3B
−$59.7M (−0.1%) vs. Q3 2022
New holders
185
438 more added
Sold out
64
440 more reduced

24 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 1,224 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2022: $68.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2022.

Institutions holding VRTX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Vontobel Holding Ltd.62,699$17.9M0.18%+3,573+6.0%Added
Tredje AP-fonden62,067$17.9M0.31%+4,418+7.7%Added
Prudential PLC62,151$17.9M0.23%+3,879+6.7%Added
State of Alaska, Department of Revenue63,310$18.3M0.23%+6,940+12.3%Added
Rafferty Asset Management, LLC63,552$18.4M0.15%+2,041+3.3%Added
HighTower Advisors, LLC63,828$18.4M0.04%+13,869+27.8%Added
CIBC Asset Management Inc64,461$18.6M0.08%−1,577−2.4%Reduced
Cullinan Associates Inc64,881$18.7M1.04%−19,400−23.0%Reduced
Capital International Ltd65,455$18.9M1.30%−5,395−7.6%Reduced
Creative Planning65,460$18.9M0.03%+56,673+645.0%Added
Commonwealth Equity Services, LLC66,295$19.1M0.05%+2,992+4.7%Added
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund66,888$19.3M0.27%−34,898−34.3%Reduced
Summit Global Investments68,389$19.7M1.67%−4,619−6.3%Reduced
Cercano Management LLC68,450$19.8M0.80%+68,450New
Moody Lynn & Lieberson, LLC68,809$19.9M1.82%+19,423+39.3%Added
Stifel Financial Corp69,763$20.1M0.03%+5,939+9.3%Added
Arizona State Retirement System69,877$20.2M0.19%+356+0.5%Added
Amalgamated Bank69,909$20.2M0.18%−5,767−7.6%Reduced
The PNC Financial Services Group, Inc.70,275$20.3M0.02%−2,328−3.2%Reduced
Formuepleje A/S71,712$20.7M1.75%+31,833+79.8%Added
Gateway Investment Advisers LLC72,217$20.9M0.26%−4,207−5.5%Reduced
Hallmark Capital Management Inc72,247$20.9M1.94%−6,879−8.7%Reduced
State of Michigan Retirement System72,923$21.1M0.15%−500−0.7%Reduced
SEI Investments Co74,333$21.5M0.05%−37,235−33.4%Reduced
Beacon Investment Advisory Services, Inc.74,840$21.6M1.11%+423+0.6%Added
MetLife Investment Management76,636$22.1M0.17%−1,447−1.9%Reduced
Boston Common Asset Management, LLC77,304$22.3M1.07%+2,027+2.7%Added
Natixis78,478$22.7M0.13%+55,193+237.0%Added
Nisa Investment Advisors, LLC79,530$23.0M0.18%−1,550−1.9%Reduced
Rhenman & Partners Asset Management AB80,000$23.1M2.41%−16,000−16.7%Reduced
Erste Asset Management GmbH82,130$23.7M0.50%−393−0.5%Reduced
Martingale Asset Management L P83,185$24.0M0.47%−2,453−2.9%Reduced
Vestcor Inc84,246$24.3M0.89%+4,524+5.7%Added
Railway Pension Investments Ltd85,400$24.7M0.25%+36,500+74.6%Added
Worldquant Millennium Advisors LLC88,282$25.5M0.58%+56,520+177.9%Added
Royal London Asset Management Ltd90,877$26.2M0.12%+4,395+5.1%Added
Calamos Advisors LLC91,757$26.5M0.13%−16,171−15.0%Reduced
American International Group, Inc.93,288$26.9M0.19%−5,141−5.2%Reduced
Illinois Municipal Retirement Fund93,366$27.0M0.61%+3,918+4.4%Added
C WorldWide Group Holding A/S93,557$27.0M0.36%00.0%Unchanged
Colony Group LLC93,995$27.1M0.38%+7,769+9.0%Added
Cubist Systematic Strategies, LLC94,395$27.3M0.23%+8,404+9.8%Added
Oregon Public Employees Retirement Fund94,845$27.4M0.35%+14,571+18.2%Added
Thrivent Financial for Lutherans95,177$27.5M0.07%−137−0.1%Reduced
Renaissance Group LLC95,604$27.6M1.35%−748−0.8%Reduced
Ossiam96,059$27.7M0.72%+1,765+1.9%Added
Bridgewater Associates, LP100,819$29.1M0.16%−63,172−38.5%Reduced
Unigestion Holding SA105,226$30.4M1.61%+8,161+8.4%Added
Mackenzie Financial Corp108,902$31.4M0.05%−9,220−7.8%Reduced
STRS Ohio109,338$31.6M0.14%−6,357−5.5%Reduced
D. E. Shaw & Co., Inc.110,533$31.9M0.05%−7,720−6.5%Reduced
Point72 Asset Management, L.P.110,839$32.0M0.12%+3,439+3.2%Added
Panagora Asset Management Inc110,942$32.0M0.21%+34,885+45.9%Added
Natixis Investment Managers International111,300$32.1M2.40%−14,825−11.8%Reduced
Atalanta Sosnoff Capital, LLC112,234$32.4M1.00%−11,420−9.2%Reduced
Grantham, Mayo, Van Otterloo & Co. LLC117,200$33.8M0.18%+4,200+3.7%Added
Asset Management One Co.,Ltd.118,935$34.4M0.17%−7,130−5.7%Reduced
Cookson Peirce & Co Inc119,115$34.4M2.24%+59,543+100.0%Added
ARK Investment Management LLCSuperinvestorARK Invest122,197$35.3M0.31%−35,248−22.4%Reduced
Mn Services Vermogensbeheer B.V.123,400$35.6M0.40%−18,400−13.0%Reduced
AMF Pensionsforsakring AB123,575$35.7M0.41%+34,879+39.3%Added
Janney Montgomery Scott LLC128,584$37.1M0.14%+21,258+19.8%Added
Banco Bilbao Vizcaya Argentaria, S.A.129,492$37.4M0.55%+4,697+3.8%Added
Jupiter Asset Management Ltd130,515$37.7M0.55%+38,968+42.6%Added
Treasurer of the State of North Carolina131,565$38.0M0.23%+5,844+4.6%Added
Putnam Investments LLC133,972$38.7M0.07%−9,309−6.5%Reduced
Toronto Dominion Bank136,330$39.3M0.06%+20,190+17.4%Added
National Bank of Canada138,169$39.9M0.11%+89,411+183.4%Added
Teacher Retirement System of Texas141,130$40.8M0.30%−4,984−3.4%Reduced
Lazard Asset Management LLC142,441$41.1M0.06%−481,400−77.2%Reduced
Ardevora Asset Management LLP142,900$41.3M0.70%+142,900New
CI Private Wealth, LLC145,326$42.0M0.15%+145,326New
Country Trust Bank147,423$42.6M1.26%−940−0.6%Reduced
Armistice Capital, LLC148,000$42.7M1.15%−2,000−1.3%Reduced
Teachers Retirement System of the State of Kentucky149,187$43.1M0.45%−610.0%Reduced
Federated Hermes, Inc.151,022$43.6M0.12%−5,368−3.4%Reduced
State of New Jersey Common Pension Fund D151,502$43.8M0.17%+1,228+0.8%Added
Aviva PLC152,261$44.0M0.22%−18,744−11.0%Reduced
Public Employees Retirement System of Ohio156,418$45.2M0.20%+917+0.6%Added
Sofinnova Investments, Inc.156,989$45.3M2.75%+156,989New
Acadian Asset Management LLC157,441$45.4M0.22%+35,552+29.2%Added
Provident Investment Management, Inc.160,727$46.4M5.50%−1,300−0.8%Reduced
Van Eck Associates Corp163,663$47.3M0.12%−11,507−6.6%Reduced
Pinebridge Investments, L.P.163,772$47.3M0.57%+2,683+1.7%Added
Clal Insurance Enterprises Holdings Ltd165,240$47.7M0.72%−47,000−22.1%Reduced
LPL Financial LLC165,339$47.7M0.04%+32,264+24.2%Added
Guggenheim Capital LLC168,959$48.8M0.43%−6,140−3.5%Reduced
Bank Julius Baer & Co. Ltd, Zurich170,370$49.2M0.34%+162,295+2,009.8%Added
Truist Financial Corp171,444$49.5M0.09%+62,866+57.9%Added
State of Wisconsin Investment Board171,502$49.5M0.16%−7,591−4.2%Reduced
Avidity Partners Management LP172,000$49.7M1.16%−340,800−66.5%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main172,000$49.7M0.09%−5,674−3.2%Reduced
Bowen Hanes & Co Inc175,210$50.6M1.79%−5,800−3.2%Reduced
State of Tennessee, Treasury Department175,386$50.6M0.24%−68,077−28.0%Reduced
Adage Capital Partners GP, L.L.C.179,890$51.9M0.12%−157,273−46.6%Reduced
Storebrand Asset Management AS181,383$52.4M0.29%+13,716+8.2%Added
Standard Life Aberdeen plc183,816$53.1M0.14%−2,999−1.6%Reduced
Welch & Forbes LLC188,171$54.3M0.97%−1,287−0.7%Reduced
Artisan Partners Limited Partnership188,470$54.4M0.10%−39,234−17.2%Reduced
Glenmede Trust Co NA190,703$55.1M0.32%+30,980+19.4%Added