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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,072
+48 vs. Q4 2021
Shares held
235.3M
+5.08M (+2.2%) vs. Q4 2021
Total value
$60.9B
+$10.5B (+20.9%) vs. Q4 2021
New holders
150
417 more added
Sold out
102
373 more reduced

10 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 1,072 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2022: $60.9B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2021.

Institutions holding VRTX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
State of Tennessee, Treasury Department308,979$80.6M0.31%+65,837+27.1%Added
Tekla Capital Management LLC308,884$80.6M2.83%+35,838+13.1%Added
Envestnet Asset Management Inc307,739$80.3M0.04%+38,499+14.3%Added
AXA S.A.307,619$80.3M0.23%−98,580−24.3%Reduced
Principal Financial Group Inc300,837$78.5M0.05%−5,475−1.8%Reduced
Polar Capital Holdings Plc300,280$78.4M0.46%−74,720−19.9%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)286,567$74.8M0.37%+160,264+126.9%Added
Virginia Retirement Systems Et Al284,800$74.3M0.70%−16,100−5.4%Reduced
Macquarie Group Ltd280,858$73.3M0.07%−23,399−7.7%Reduced
KBC Group NV278,439$72.7M0.29%−306,815−52.4%Reduced
Scout Investments, Inc.270,533$70.6M1.13%+11,775+4.6%Added
BNP Paribas Arbitrage, SA268,469$70.1M0.14%+98,344+57.8%Added
Nordea Investment Management AB269,704$69.6M0.09%+2,710+1.0%Added
Clal Insurance Enterprises Holdings Ltd265,000$69.2M0.73%−216,000−44.9%Reduced
Teachers Retirement System of the State of Kentucky261,130$68.1M0.66%+80,863+44.9%Added
Korea Investment CORP252,209$65.8M0.16%+28,512+12.7%Added
State of Wisconsin Investment Board250,778$65.4M0.14%+43,978+21.3%Added
Mitsubishi UFJ Trust & Banking Corp245,744$64.1M0.15%−9,025−3.5%Reduced
Hardman Johnston Global Advisors LLC245,004$63.9M2.05%+36,380+17.4%Added
Neuberger Berman Group LLC242,769$63.4M0.05%−420.0%Reduced
Federated Hermes, Inc.240,148$62.7M0.14%−26,936−10.1%Reduced
Robeco Institutional Asset Management B.V.236,832$61.8M0.15%+38,514+19.4%Added
Armistice Capital, LLC236,000$61.6M1.75%−252,000−51.6%Reduced
Birch Hill Investment Advisors LLC234,102$61.1M3.26%−13,137−5.3%Reduced
Skandinaviska Enskilda Banken AB (publ)232,032$60.6M0.36%−55,892−19.4%Reduced
Natixis Investment Managers International228,605$59.7M1.04%−26,125−10.3%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main223,292$58.3M0.09%+19,506+9.6%Added
Guggenheim Capital LLC220,611$57.6M0.35%+8,939+4.2%Added
Handelsbanken Fonder AB207,881$54.3M0.30%+13,837+7.1%Added
Welch & Forbes LLC195,558$51.0M0.80%+5,628+3.0%Added
Bowen Hanes & Co Inc192,630$50.3M1.50%−1,490−0.8%Reduced
Provident Investment Management, Inc.187,314$48.9M4.68%+2,135+1.2%Added
Mn Services Vermogensbeheer B.V.186,700$48.7M0.32%−11,700−5.9%Reduced
Panagora Asset Management Inc184,997$48.3M0.26%−89,263−32.5%Reduced
Putnam Investments LLC169,082$44.1M0.07%−12,490−6.9%Reduced
Teacher Retirement System of Texas162,546$42.4M0.22%+49,786+44.2%Added
Glenmede Trust Co NA160,975$42.0M0.21%+147,028+1,054.2%Added
Asset Management One Co.,Ltd.155,013$40.5M0.16%−15,309−9.0%Reduced
Chevy Chase Trust Holdings, Inc.153,212$40.0M0.14%+462+0.3%Added
Public Employees Retirement System of Ohio152,699$39.9M0.14%−4,310−2.7%Reduced
State of New Jersey Common Pension Fund D149,774$39.1M0.12%−2,855−1.9%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.148,247$38.7M0.15%+12,079+8.9%Added
Aviva PLC147,748$38.6M0.19%+54,224+58.0%Added
M.D. Sass Investors Services, Inc.146,160$38.1M6.53%+54,275+59.1%Added
Van Eck Associates Corp144,730$37.8M0.08%−14,792−9.3%Reduced
FIL Ltd141,885$37.0M0.04%+137,222+2,942.8%Added
Country Trust Bank137,638$35.9M1.00%−42,030−23.4%Reduced
Twin Tree Management, LP136,591$35.6M0.70%−4,228−3.0%Reduced
LPL Financial LLC136,504$35.6M0.03%+16,002+13.3%Added
Renaissance Group LLC135,306$35.3M1.59%+10,191+8.1%Added
Toronto Dominion Bank131,172$34.2M0.05%−24,109−15.5%Reduced
Storebrand Asset Management AS129,735$33.9M0.16%+40,511+45.4%Added
Jupiter Asset Management Ltd126,017$32.9M0.39%+123,034+4,124.5%Added
Capital International Investors125,595$32.8M0.01%−1,901,637−93.8%Reduced
AMF Pensionsforsakring AB124,797$32.6M0.24%−1,120−0.9%Reduced
STRS Ohio117,638$30.7M0.11%+8,207+7.5%Added
Treasurer of the State of North Carolina117,575$30.7M0.17%+2,691+2.3%Added
NN Investment Partners Holdings N.V.114,469$29.9M0.16%+33,337+41.1%Added
Voya Investment Management LLC112,368$29.3M0.06%−3,479−3.0%Reduced
Truist Financial Corp110,974$29.0M0.05%+26,836+31.9%Added
C WorldWide Group Holding A/S108,557$28.3M0.31%00.0%Unchanged
Janney Montgomery Scott LLC106,911$27.9M0.12%+52,024+94.8%Added
Todd Asset Management LLC105,794$27.6M0.61%+105,794New
Calamos Advisors LLC104,987$27.4M0.11%+13,837+15.2%Added
Thrivent Financial for Lutherans104,872$27.4M0.05%+52,466+100.1%Added
American International Group, Inc.103,562$27.0M0.15%−2,826−2.7%Reduced
Susquehanna International Group, LLP102,853$26.8M0.04%−233,472−69.4%Reduced
Dai-Ichi Life Insurance Company, Ltd102,447$26.7M0.43%+430.0%Added
Roosevelt Investment Group LLC100,079$26.1M1.56%+2,939+3.0%Added
Mackenzie Financial Corp99,325$25.9M0.03%+11,876+13.6%Added
Cullinan Associates Inc98,316$25.7M1.35%−594−0.6%Reduced
Standard Life Aberdeen plc96,383$25.1M0.06%+1,760+1.9%Added
Sofinnova Investments, Inc.95,003$24.8M2.08%+95,003New
HighTower Advisors, LLC94,309$24.6M0.05%+29,446+45.4%Added
Ossiam94,074$24.6M0.64%+4,020+4.5%Added
South Dakota Investment Council93,495$24.4M0.48%−30,799−24.8%Reduced
Alberta Investment Management Corp91,200$23.8M0.14%+12,000+15.2%Added
Summit Global Investments90,562$23.6M1.74%−4,482−4.7%Reduced
Hallmark Capital Management Inc90,503$23.6M1.97%−4,735−5.0%Reduced
Royal London Asset Management Ltd89,765$23.4M0.09%+2,978+3.4%Added
Rhenman & Partners Asset Management AB89,500$23.4M2.30%−75,500−45.8%Reduced
Vontobel Holding Ltd.90,691$23.3M0.20%−26,006−22.3%Reduced
Gateway Investment Advisers LLC87,253$22.8M0.22%−2,693−3.0%Reduced
Chiron Investment Management, LLC87,121$22.7M2.67%+87,121New
Cubist Systematic Strategies, LLC86,574$22.6M0.19%+54,686+171.5%Added
Banque Pictet & Cie SA85,596$22.3M0.17%−6,905−7.5%Reduced
Great Point Partners LLC85,000$22.2M5.37%00.0%Unchanged
Pura Vida Investments, LLC84,057$21.9M2.65%+59,421+241.2%Added
Bridger Management, LLC82,800$21.6M3.54%+23,400+39.4%Added
Erste Asset Management GmbH84,000$21.6M0.41%+22,800+37.3%Added
Eagle Health Investments LP82,144$21.4M5.28%00.0%Unchanged
Grantham, Mayo, Van Otterloo & Co. LLC82,100$21.4M0.10%+82,100New
Nikko Asset Management Americas, Inc.81,535$21.4M0.16%−32,454−28.5%Reduced
Stifel Financial Corp81,543$21.3M0.03%−14,790−15.4%Reduced
Tower Research Capital LLC (TRC)77,497$20.2M0.19%+47,754+160.6%Added
Van Hulzen Asset Management, LLC77,300$20.2M2.14%+7,399+10.6%Added
Banco Bilbao Vizcaya Argentaria, S.A.72,852$19.7M0.27%−1,787−2.4%Reduced
SG Americas Securities, LLC75,285$19.6M0.18%+41,131+120.4%Added
Nisa Investment Advisors, LLC75,067$19.6M0.14%−10,995−12.8%Reduced
Woodline Partners LP74,671$19.5M0.32%−29,109−28.0%Reduced