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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Citizens Financial Group Inc47,500$10.4M0.35%+42,987+952.5%Added
Point72 Asset Management, L.P.47,600$10.5M0.05%+47,600New
Industrial Alliance Investment Management Inc.47,632$10.5M0.24%+47,632New
Advisor Group Holdings, Inc.48,529$10.7M0.02%+15,222+45.7%Added
Squarepoint Ops LLC49,545$10.9M0.05%−104,211−67.8%Reduced
W.G. Shaheen & Associates DBA Whitney & Co50,135$11.0M1.62%+733+1.5%Added
The PNC Financial Services Group, Inc.51,537$11.3M0.01%+20,397+65.5%Added
Thrivent Financial for Lutherans52,406$11.5M0.02%+8,056+18.2%Added
Rafferty Asset Management, LLC54,435$12.0M0.06%+7,270+15.4%Added
Janney Montgomery Scott LLC54,887$12.1M0.05%+2,439+4.7%Added
Greenwood Capital Associates LLC55,316$12.1M1.72%−232−0.4%Reduced
MetLife Investment Management56,175$12.3M0.10%−2,419−4.1%Reduced
Capital Group Private Client Services, Inc.57,166$12.6M0.13%−4,971−8.0%Reduced
Illinois Municipal Retirement Fund58,502$12.8M0.36%+11,467+24.4%Added
Profund Advisors LLC58,608$12.9M0.42%−8,612−12.8%Reduced
Bridger Management, LLC59,400$13.0M1.69%+59,400New
Erste Asset Management GmbH61,200$13.7M0.25%−800−1.3%Reduced
HRT Financial LP63,603$14.0M0.08%+63,603New
State of Michigan Retirement System64,034$14.1M0.07%−1,100−1.7%Reduced
Davidson Investment Advisors64,309$14.1M1.01%−413−0.6%Reduced
USS Investment Management Ltd64,412$14.1M0.11%00.0%Unchanged
HighTower Advisors, LLC64,863$14.2M0.03%+11,205+20.9%Added
Commonwealth Equity Services, LLC65,403$14.4M0.03%−9,388−12.6%Reduced
Jane Street Group, LLC66,068$14.5M0.03%−69,179−51.2%Reduced
CIBC Asset Management Inc67,642$14.9M0.05%+6,305+10.3%Added
PFS Investments Inc.68,783$15.1M0.29%+744+1.1%Added
Van Hulzen Asset Management, LLC69,901$15.4M1.68%+69,901New
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund70,487$15.5M0.14%−700−1.0%Reduced
Arizona State Retirement System71,052$15.6M0.12%−1,136−1.6%Reduced
Amalgamated Bank71,174$15.6M0.12%+5,885+9.0%Added
Banco Bilbao Vizcaya Argentaria, S.A.74,639$16.6M0.22%+49,830+200.9%Added
Andra AP-fonden75,600$16.6M0.34%+4,100+5.7%Added
Baird Financial Group, Inc.76,028$16.7M0.04%+1,838+2.5%Added
International Biotechnology Trust PLC77,222$17.0M3.78%00.0%Unchanged
Forsta Ap-Fonden77,300$17.0M0.17%+1,100+1.4%Added
Kingdon Capital Management, L.L.C.77,300$17.0M2.54%+77,300New
BI Asset Management Fondsmaeglerselskab A/S78,877$17.3M0.64%−443−0.6%Reduced
Alberta Investment Management Corp79,200$17.4M0.11%−12,452−13.6%Reduced
EULAV Asset Management80,000$17.6M0.44%−28,000−25.9%Reduced
2Xideas AG80,226$17.6M1.06%+23,363+41.1%Added
NN Investment Partners Holdings N.V.81,132$17.8M0.09%−25,080−23.6%Reduced
Magnetar Financial LLC81,724$17.9M0.18%+17,487+27.2%Added
Eagle Health Investments LP82,144$18.0M4.39%+52,600+178.0%Added
Capital International Ltd83,591$18.4M0.93%+10,036+13.6%Added
Truist Financial Corp84,138$18.5M0.03%+2,887+3.6%Added
Great Point Partners LLC85,000$18.7M4.17%00.0%Unchanged
Healthcare of Ontario Pension Plan Trust Fund85,144$18.7M0.04%−44,016−34.1%Reduced
Royal London Asset Management Ltd86,787$19.1M0.07%−4,005−4.4%Reduced
Mackenzie Financial Corp87,449$19.2M0.03%+1,896+2.2%Added
Storebrand Asset Management AS89,224$19.6M0.09%−4,632−4.9%Reduced
Gateway Investment Advisers LLC89,946$19.8M0.19%−12,423−12.1%Reduced
Ossiam90,054$19.8M0.52%+87,369+3,254.0%Added
Calamos Advisors LLC91,150$20.0M0.08%−19,807−17.9%Reduced
M.D. Sass Investors Services, Inc.91,885$20.2M3.14%+91,885New
Banque Pictet & Cie SA92,501$20.3M0.15%+57,611+165.1%Added
Aviva PLC93,524$20.5M0.09%−8,617−8.4%Reduced
Standard Life Aberdeen plc94,623$20.8M0.05%−420,216−81.6%Reduced
Summit Global Investments95,044$20.9M1.34%+95,044New
Hallmark Capital Management Inc95,238$20.9M1.68%−1,125−1.2%Reduced
Nisa Investment Advisors, LLC86,062$20.9M0.16%−5,652−6.2%Reduced
Stifel Financial Corp96,333$21.2M0.03%−16,531−14.6%Reduced
Roosevelt Investment Group LLC97,140$21.3M1.18%+1,673+1.8%Added
Group One Trading, L.P.98,437$21.6M0.41%+26,514+36.9%Added
Cullinan Associates Inc98,910$21.7M1.11%−215−0.2%Reduced
Bank of Nova Scotia101,259$22.2M0.03%−387,200−79.3%Reduced
Dai-Ichi Life Insurance Company, Ltd102,404$22.5M0.29%−18,000−14.9%Reduced
Woodline Partners LP103,780$22.8M0.33%+23,293+28.9%Added
American International Group, Inc.106,388$23.4M0.12%−2,130−2.0%Reduced
Clough Capital Partners L P107,110$23.5M1.58%+17,500+19.5%Added
Capital International Inc107,173$23.5M0.22%+13,572+14.5%Added
C WorldWide Group Holding A/S108,557$23.8M0.23%00.0%Unchanged
STRS Ohio109,431$24.0M0.08%−2,688−2.4%Reduced
Teacher Retirement System of Texas112,760$24.8M0.11%−16,482−12.8%Reduced
Nikko Asset Management Americas, Inc.113,989$24.9M0.13%−13,207−10.4%Reduced
Treasurer of the State of North Carolina114,884$25.2M0.13%+1,673+1.5%Added
Voya Investment Management LLC115,847$25.4M0.05%−13,143−10.2%Reduced
Vontobel Holding Ltd.116,697$26.0M0.22%+18,953+19.4%Added
LPL Financial LLC120,502$26.5M0.02%+7,919+7.0%Added
South Dakota Investment Council124,294$27.3M0.46%+45,680+58.1%Added
Renaissance Group LLC125,115$27.5M1.12%+6,265+5.3%Added
AMF Pensionsforsakring AB125,917$27.7M0.19%−16,532−11.6%Reduced
Zurcher Kantonalbank (Zurich Cantonalbank)126,303$27.7M0.13%−19,306−13.3%Reduced
Mitsubishi UFJ Kokusai Asset Management Co., Ltd.136,168$30.3M0.12%+19,729+16.9%Added
Voloridge Investment Management, LLC139,353$30.6M0.17%−397,543−74.0%Reduced
Twin Tree Management, LP140,819$30.9M0.75%+122,616+673.6%Added
Marshall Wace, LLP150,000$32.9M0.07%−406,678−73.1%Reduced
Melqart Asset Management (UK) Ltd150,000$32.9M1.86%+10,000+7.1%Added
State of New Jersey Common Pension Fund D152,629$33.5M0.10%−2,027−1.3%Reduced
Chevy Chase Trust Holdings, Inc.152,750$33.5M0.11%−6,536−4.1%Reduced
Varenne Capital Partners155,070$34.1M5.05%+155,070New
Toronto Dominion Bank155,281$34.1M0.05%−69,234−30.8%Reduced
Public Employees Retirement System of Ohio157,009$34.5M0.12%−7,845−4.8%Reduced
Van Eck Associates Corp159,522$35.0M0.08%−19,656−11.0%Reduced
Rhenman & Partners Asset Management AB165,000$36.7M2.44%00.0%Unchanged
BNP Paribas Arbitrage, SA170,125$37.4M0.09%+43,429+34.3%Added
Victory Capital Management Inc170,494$37.4M0.03%+4,717+2.8%Added
Asset Management One Co.,Ltd.170,322$38.0M0.13%+13,382+8.5%Added
Country Trust Bank179,668$39.5M1.07%+19,269+12.0%Added
Teachers Retirement System of the State of Kentucky180,267$39.6M0.35%−1,345−0.7%Reduced
Putnam Investments LLC181,572$39.9M0.06%−337,467−65.0%Reduced