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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Edmond de Rothschild Holding S.A.20,039$4.40M0.10%−5,677−22.1%Reduced
Natixis20,423$4.49M0.02%−166,652−89.1%Reduced
Associated Banc-Corp20,597$4.52M0.17%−5,480−21.0%Reduced
Davenport & Co LLC20,717$4.55M0.03%+2,318+12.6%Added
Pinebridge Investments, L.P.21,023$4.62M0.05%−94,562−81.8%Reduced
Oregon Public Employees Retirement Fund21,040$4.62M0.05%−609−2.8%Reduced
Sepio Capital, LP21,162$4.65M0.35%+333+1.6%Added
Advisors Asset Management, Inc.21,242$4.66M0.07%−4,458−17.3%Reduced
Pacer Advisors, Inc.21,453$4.71M0.05%−7,435−25.7%Reduced
Securian Asset Management, Inc21,523$4.73M0.09%−891−4.0%Reduced
Quantitative Investment Management, LLC21,622$4.75M0.67%+21,622New
Northwest & Ethical Investments L.P.21,641$4.75M0.14%+21,641New
Sumitomo Mitsui DS Asset Management Company, Ltd21,815$4.79M0.10%+1,047+5.0%Added
Cornerstone Advisors, LLC22,000$4.83M0.26%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.22,233$4.88M0.02%−2,476−10.0%Reduced
Beacon Pointe Advisors, LLC22,518$4.95M0.13%−6,314−21.9%Reduced
Gotham Asset Management, LLC22,755$5.00M0.16%+2,488+12.3%Added
Daiwa Securities Group Inc.23,175$5.09M0.03%+1,483+6.8%Added
Meiji Yasuda Asset Management Co Ltd.23,206$5.10M0.32%+271+1.2%Added
Formuepleje A/S23,389$5.14M0.20%−3,953−14.5%Reduced
Fagan Associates, Inc.23,419$5.14M0.98%+3,012+14.8%Added
Northwest Bancshares, Inc.23,445$5.15M1.01%+1,079+4.8%Added
Scotia Capital Inc.23,483$5.16M0.03%+7,458+46.5%Added
Blair William & Co23,489$5.16M0.02%+7,239+44.5%Added
Foster Victor Wealth Advisors, LLC22,933$5.19M0.71%+2,121+10.2%Added
B. Metzler seel. Sohn & Co. AG23,315$5.19M0.07%+23,315New
Norinchukin Bank, The23,875$5.24M0.07%−1,919−7.4%Reduced
AIMZ Investment Advisors, LLC24,080$5.29M2.06%+400+1.7%Added
Edgewood Management LLC24,088$5.29M0.01%00.0%Unchanged
Arrowstreet Capital, Limited Partnership24,249$5.33M0.01%+24,249New
Shelton Capital Management24,277$5.33M0.19%+477+2.0%Added
Wealth Enhancement Advisory Services, LLC22,043$5.37M0.08%+22,043New
PDT Partners, LLC24,508$5.38M0.41%−2,093−7.9%Reduced
Covea Finance24,544$5.39M0.47%+24,544New
Pura Vida Investments, LLC24,636$5.41M0.56%−5,364−17.9%Reduced
Bender Robert & Associates30,110$5.46M1.58%00.0%Unchanged
Fisher Asset Management, LLC25,271$5.55M0.00%+1,157+4.8%Added
Raymond James Financial Services Advisors, Inc.25,355$5.57M0.01%+742+3.0%Added
Distillate Capital Partners LLC25,728$5.65M0.95%+8,782+51.8%Added
Hartford Investment Management Co25,796$5.67M0.13%+1,605+6.6%Added
Westpac Banking Corp26,000$5.71M0.06%−73−0.3%Reduced
Atria Investments LLC26,620$5.85M0.10%+1,433+5.7%Added
Xponance, Inc.26,767$5.88M0.09%+3,078+13.0%Added
Philadelphia Trust Co26,985$5.93M0.43%+25,100+1,331.6%Added
Ilmarinen Mutual Pension Insurance Co28,000$6.15M0.07%00.0%Unchanged
Nissay Asset Management Corp28,587$6.28M0.05%+1,026+3.7%Added
Tredje AP-fonden28,666$6.29M0.12%00.0%Unchanged
Shell Asset Management Co28,839$6.33M0.13%−8,012−21.7%Reduced
Varma Mutual Pension Insurance Co29,287$6.43M0.09%00.0%Unchanged
Louisiana State Employees Retirement System29,400$6.46M0.14%−100−0.3%Reduced
TD Waterhouse Canada Inc.29,292$6.53M0.06%+29,292New
Tower Research Capital LLC (TRC)29,743$6.53M0.11%+3,872+15.0%Added
Rockefeller Capital Management L.P.30,121$6.61M0.03%+6,248+26.2%Added
Vident Investment Advisory, LLC30,124$6.62M0.17%+9,645+47.1%Added
First Republic Investment Management, Inc.30,432$6.68M0.01%+23,254+324.0%Added
Beacon Investment Advisory Services, Inc.30,557$6.71M0.26%−5,945−16.3%Reduced
Private Advisor Group, LLC30,979$6.80M0.05%−903−2.8%Reduced
Boston Common Asset Management, LLC31,040$6.82M0.28%−505−1.6%Reduced
Walleye Capital LLC31,203$6.85M0.23%+2,373+8.2%Added
Gabelli Funds LLC31,296$6.87M0.04%+6,000+23.7%Added
Privium Fund Management B.V.31,000$6.90M1.37%+31,000New
LVM Capital Management Ltd31,846$6.99M0.93%+321+1.0%Added
Cubist Systematic Strategies, LLC31,888$7.00M0.07%−5,921−15.7%Reduced
Commonwealth of Pennsylvania Public School Empls Retrmt Sys31,913$7.01M0.07%−598−1.8%Reduced
Hudson Bay Capital Management LP32,500$7.14M0.08%−30,000−48.0%Reduced
Yousif Capital Management, LLC33,148$7.28M0.08%+33,148New
Metropolitan Life Insurance Co33,498$7.36M0.10%−1,335−3.8%Reduced
Mutual of America Capital Management LLC33,550$7.37M0.07%−464−1.4%Reduced
Azimuth Capital Management LLC33,575$7.37M0.30%−194−0.6%Reduced
AlphaCrest Capital Management LLC33,735$7.41M0.28%+2,115+6.7%Added
SEI Investments Co34,329$7.48M0.01%−1,291−3.6%Reduced
SG Americas Securities, LLC34,154$7.50M0.05%+25,894+313.5%Added
IFM Investors Pty Ltd34,197$7.51M0.14%−403−1.2%Reduced
Texas Permanent School Fund35,018$7.69M0.09%−5,060−12.6%Reduced
Jacobs Levy Equity Management, Inc35,264$7.74M0.05%−421,858−92.3%Reduced
Comerica Bank34,325$7.79M0.06%−52,411−60.4%Reduced
Prudential PLC36,041$7.92M0.11%−1,126−3.0%Reduced
State of Alaska, Department of Revenue36,800$8.08M0.08%−3,035−7.6%Reduced
Exencial Wealth Advisors, LLC37,817$8.30M0.40%+1,213+3.3%Added
Mackay Shields LLC37,983$8.34M0.07%−1,594−4.0%Reduced
Nicholas Investment Partners, LP38,287$8.41M0.53%+38,287New
Seizert Capital Partners, LLC38,598$8.48M0.38%+3,640+10.4%Added
Sector Gamma AS39,069$8.58M2.02%+39,069New
Bulltick Wealth Management, LLC40,172$8.82M1.80%−2,146−5.1%Reduced
Thompson Siegel & Walmsley LLC42,062$9.24M0.13%−3,039−6.7%Reduced
Employees Retirement System of Texas42,200$9.27M0.10%00.0%Unchanged
Public Sector Pension Investment Board42,425$9.32M0.05%−1,290−3.0%Reduced
Brookfield Asset Management Inc.42,697$9.38M0.04%+29,816+231.5%Added
Shelter Mutual Insurance Co43,300$9.51M2.47%00.0%Unchanged
Gulf International Bank (UK) Ltd43,475$9.55M0.13%−8,919−17.0%Reduced
Factory Mutual Insurance Co43,200$9.66M0.14%−139,455−76.3%Reduced
ING Groep NV43,987$9.66M0.09%+17,641+67.0%Added
Edgemoor Investment Advisors, Inc.44,328$9.73M1.00%+9,654+27.8%Added
Weiss Multi-Strategy Advisers LLC44,693$9.81M0.23%−10,456−19.0%Reduced
ExodusPoint Capital Management, LP44,933$9.87M0.12%+5,821+14.9%Added
British Columbia Investment Management Corp45,612$10.0M0.06%−2,337−4.9%Reduced
Schroder Investment Management Group45,894$10.1M0.01%−1,285−2.7%Reduced
Utah Retirement Systems46,239$10.2M0.13%−600−1.3%Reduced
Capital International Sarl46,555$10.2M0.49%+33,939+269.0%Added
Banco Santander, S.A.47,262$10.4M0.06%+1,300+2.8%Added