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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Provident Investment Management, Inc.185,179$40.7M3.67%+1,813+1.0%Added
Welch & Forbes LLC189,930$41.7M0.62%−12,107−6.0%Reduced
Handelsbanken Fonder AB194,044$42.6M0.21%+121,656+168.1%Added
Bowen Hanes & Co Inc194,120$42.6M1.20%+15,475+8.7%Added
Robeco Institutional Asset Management B.V.198,318$43.6M0.09%−4,637−2.3%Reduced
Mn Services Vermogensbeheer B.V.198,400$43.6M0.26%+4,800+2.5%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main203,786$45.0M0.06%−28,486−12.3%Reduced
State of Wisconsin Investment Board206,800$45.4M0.09%−62,201−23.1%Reduced
Hardman Johnston Global Advisors LLC208,624$45.8M1.24%+19,950+10.6%Added
Balyasny Asset Management LLC211,347$46.4M0.20%+56,709+36.7%Added
Guggenheim Capital LLC211,672$46.5M0.24%+4,577+2.2%Added
Adage Capital Partners GP, L.L.C.220,890$48.5M0.09%+46,930+27.0%Added
Korea Investment CORP223,697$49.1M0.13%+78,111+53.7%Added
Neuberger Berman Group LLC242,811$52.4M0.04%−43,385−15.2%Reduced
State of Tennessee, Treasury Department243,142$53.4M0.20%+49,402+25.5%Added
BNP PARIBAS ASSET MANAGEMENT Holding S.A.246,379$54.1M0.18%+42,137+20.6%Added
Birch Hill Investment Advisors LLC247,239$54.3M2.69%+50,095+25.4%Added
Citadel Advisors LLC252,591$55.5M0.06%−161,538−39.0%Reduced
Natixis Investment Managers International254,730$55.9M3.10%+254,730New
Mitsubishi UFJ Trust & Banking Corp254,769$55.9M0.12%−17,977−6.6%Reduced
Scout Investments, Inc.258,758$56.8M0.83%+12,385+5.0%Added
Federated Hermes, Inc.267,084$58.7M0.11%+16,440+6.6%Added
Envestnet Asset Management Inc269,240$59.1M0.03%+20,854+8.4%Added
Nordea Investment Management AB266,994$59.4M0.07%+29,813+12.6%Added
Tekla Capital Management LLC273,046$60.0M1.93%00.0%Unchanged
Panagora Asset Management Inc274,260$60.2M0.32%−115,628−29.7%Reduced
Avidity Partners Management LP280,000$61.5M1.30%−646,400−69.8%Reduced
Mirae Asset Global Investments Co., Ltd.285,187$62.7M0.13%+37,357+15.1%Added
Skandinaviska Enskilda Banken AB (publ)287,924$64.0M0.33%−10,161−3.4%Reduced
Ensign Peak Advisors, Inc295,678$64.9M0.12%−151,534−33.9%Reduced
Nomura Asset Management Co Ltd296,854$65.2M0.33%+56,197+23.4%Added
Virginia Retirement Systems Et Al300,900$66.1M0.61%−5,800−1.9%Reduced
Los Angeles Capital Management LLC302,005$66.3M0.25%+147,876+95.9%Added
Russell Investments Group, Ltd.302,361$66.5M0.11%+2,729+0.9%Added
Macquarie Group Ltd304,257$66.8M0.06%−1,046,258−77.5%Reduced
Principal Financial Group Inc306,312$67.3M0.04%−13,734−4.3%Reduced
Assenagon Asset Management S.A.322,231$70.8M0.26%+252,752+363.8%Added
State Board of Administration of Florida Retirement System324,362$71.2M0.13%−2,414−0.7%Reduced
New York State Teachers Retirement System324,548$71.3M0.14%−3,978−1.2%Reduced
TD Asset Management Inc329,779$72.4M0.06%+9,855+3.1%Added
Allspring Global Investments Holdings, LLC335,605$73.7M0.08%+335,605New
Susquehanna International Group, LLP336,325$73.9M0.11%−213,904−38.9%Reduced
DekaBank Deutsche Girozentrale338,255$76.0M0.18%−6,454−1.9%Reduced
Bank of Montreal341,874$76.1M0.04%−711,485−67.5%Reduced
UBS Group AG356,471$78.3M0.03%−146,377−29.1%Reduced
Polar Capital Holdings Plc375,000$82.3M0.43%+75,000+25.0%Added
National Pension Service379,890$83.4M0.15%+8,944+2.4%Added
HSBC Holdings PLC379,213$83.6M0.09%−21,846−5.4%Reduced
Eaton Vance Management388,956$85.4M0.10%−50,755−11.5%Reduced
Fred Alger Management, LLC389,546$85.5M0.21%+386,859+14,397.4%Added
Rhumbline Advisers392,266$86.1M0.11%+6,992+1.8%Added
Great West Life Assurance Co405,622$88.8M0.18%+16,035+4.1%Added
AXA S.A.406,199$89.2M0.23%−15,690−3.7%Reduced
Retirement Systems of Alabama433,295$95.2M0.33%−1,772−0.4%Reduced
Millennium Management LLC446,853$98.1M0.11%−248,855−35.8%Reduced
Camber Capital Management LP450,000$98.8M3.81%+450,000New
Raymond James & Associates457,083$100.4M0.08%+17,602+4.0%Added
California State Teachers Retirement System461,347$101.3M0.12%+12,765+2.8%Added
Artisan Partners Limited Partnership462,314$101.5M0.12%−2,717−0.6%Reduced
Public Employees Retirement Association of Colorado462,461$101.6M0.42%−6,646−1.4%Reduced
Manufacturers Life Insurance Company, The476,920$105.3M0.06%−116,047−19.6%Reduced
Clal Insurance Enterprises Holdings Ltd481,000$105.6M1.14%+323,500+205.4%Added
DnB Asset Management AS487,895$107.1M0.63%−22,007−4.3%Reduced
Armistice Capital, LLC488,000$107.2M2.61%−148,000−23.3%Reduced
New York State Common Retirement Fund489,848$107.6M0.11%−13,535−2.7%Reduced
ProShare Advisors LLC517,189$113.6M0.22%+144,037+38.6%Added
First Trust Advisors LP521,427$114.5M0.11%+30,756+6.3%Added
Barclays PLC580,598$127.5M0.08%+11,895+2.1%Added
KBC Group NV585,254$128.5M0.42%+305,091+108.9%Added
AQR Capital Management LLC598,483$131.4M0.24%−40,834−6.4%Reduced
Parnassus Investments619,438$136.0M0.26%00.0%Unchanged
American Century Companies Inc624,453$137.1M0.09%−145,053−18.9%Reduced
Credit Suisse AG629,495$138.2M0.11%+22,364+3.7%Added
Candriam Luxembourg S.C.A.644,632$141.6M0.90%+51,803+8.7%Added
OrbiMed Advisors LLC658,100$144.5M1.88%−219,300−25.0%Reduced
Citigroup Inc659,371$144.8M0.13%+79,762+13.8%Added
Prudential Financial Inc660,505$144.8M0.18%+49,727+8.1%Added
Allianz Asset Management GmbH660,827$145.2M0.11%−8,617−1.3%Reduced
Natixis Advisors, L.P.667,802$146.7M0.56%+51,094+8.3%Added
Swedbank AB664,156$147.7M0.25%+8,960+1.4%Added
Royal Bank of Canada703,699$154.5M0.04%−76,891−9.9%Reduced
Jennison Associates LLC783,389$172.0M0.11%−45,970−5.5%Reduced
Epoch Investment Partners, Inc.819,848$180.0M0.91%+503,347+159.0%Added
Wells Fargo & Company845,804$185.7M0.05%−285,787−25.3%Reduced
Amundi823,754$186.6M0.12%+133,856+19.4%Added
Manning & Napier Group, LLC873,972$191.9M1.60%+1,044+0.1%Added
Parametric Portfolio Associates LLC877,007$192.6M0.10%+142,022+19.3%Added
Lazard Asset Management LLC915,720$201.1M0.21%+749,784+451.9%Added
Vaughan Nelson Investment Management, L.P.923,747$202.9M2.08%+923,747New
ARK Investment Management LLCSuperinvestorARK Invest928,791$204.0M0.62%−780,960−45.7%Reduced
Dimensional Fund Advisors LP934,033$205.1M0.06%+229,487+32.6%Added
Man Group plc963,525$211.6M0.68%−247,918−20.5%Reduced
Morgan Stanley969,807$213.0M0.03%−72,706−7.0%Reduced
Swiss National Bank986,075$216.5M0.13%−37,600−3.7%Reduced
D. E. Shaw & Co., Inc.1,021,323$224.3M0.27%−693,311−40.4%Reduced
Impax Asset Management Group plc1,032,855$226.8M0.83%−41,881−3.9%Reduced
Sumitomo Mitsui Trust Holdings, Inc.1,039,746$228.3M0.14%−52,295−4.8%Reduced
Franklin Resources Inc1,059,301$232.6M0.08%+192,377+22.2%Added
APG Asset Management N.V.1,206,589$233.0M0.40%−22,100−1.8%Reduced
Invesco Ltd.1,122,158$246.4M0.06%−92,335−7.6%Reduced