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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q3 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Sep 30, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
936
−33 vs. Q2 2021
Shares held
231.6M
+111.7K (0.0%) vs. Q2 2021
Total value
$41.9B
−$4.61B (−9.9%) vs. Q2 2021
New holders
98
359 more added
Sold out
131
348 more reduced

10 institutions that held it in Q2 2021 haven't filed for Q3 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q2 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2021: 936 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ3 2021: $41.9B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q3 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q2 2021.

Institutions holding VRTX in Q3 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Teachers Retirement System of the State of Kentucky181,612$32.9M0.31%+62,100+52.0%Added
Factory Mutual Insurance Co182,655$33.1M0.41%−1,200−0.7%Reduced
Provident Investment Management, Inc.183,366$33.3M3.18%+6,531+3.7%Added
Natixis187,075$33.9M0.12%+187,075New
Hardman Johnston Global Advisors LLC188,674$34.2M0.92%−3,505−1.8%Reduced
Mn Services Vermogensbeheer B.V.193,600$35.1M0.22%+2,900+1.5%Added
State of Tennessee, Treasury Department193,740$35.1M0.14%−175,176−47.5%Reduced
Birch Hill Investment Advisors LLC197,144$35.8M1.92%+1,570+0.8%Added
Welch & Forbes LLC202,037$36.6M0.61%−4,332−2.1%Reduced
Robeco Institutional Asset Management B.V.202,955$36.8M0.08%−132−0.1%Reduced
BNP PARIBAS ASSET MANAGEMENT Holding S.A.204,242$37.0M0.14%−91,765−31.0%Reduced
Guggenheim Capital LLC207,095$37.6M0.23%−9,157−4.2%Reduced
Toronto Dominion Bank224,515$40.7M0.06%+32,565+17.0%Added
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main232,272$42.1M0.07%−57,087−19.7%Reduced
Nomura Asset Management Co Ltd240,657$43.7M0.25%+12,681+5.6%Added
Nordea Investment Management AB237,181$43.7M0.06%+24,564+11.6%Added
Scout Investments, Inc.246,373$44.7M0.67%+82,519+50.4%Added
Mirae Asset Global Investments Co., Ltd.247,830$45.0M0.11%+78,091+46.0%Added
Envestnet Asset Management Inc248,386$45.1M0.02%+53,642+27.5%Added
Federated Hermes, Inc.250,644$45.5M0.09%+78,580+45.7%Added
State of Wisconsin Investment Board269,001$48.8M0.10%−155,828−36.7%Reduced
Mitsubishi UFJ Trust & Banking Corp272,746$49.5M0.11%+1,643+0.6%Added
Tekla Capital Management LLC273,046$49.5M1.59%−122,242−30.9%Reduced
KBC Group NV280,163$50.8M0.19%−15,983−5.4%Reduced
Neuberger Berman Group LLC286,196$51.6M0.05%−123,143−30.1%Reduced
Skandinaviska Enskilda Banken AB (publ)298,085$54.1M0.30%−8,478−2.8%Reduced
Polar Capital Holdings Plc300,000$54.4M0.30%00.0%Unchanged
Russell Investments Group, Ltd.299,632$54.4M0.09%−45,095−13.1%Reduced
Virginia Retirement Systems Et Al306,700$55.6M0.57%+19,900+6.9%Added
Jupiter Asset Management Ltd306,863$55.7M0.63%+260,450+561.2%Added
Epoch Investment Partners, Inc.316,501$57.4M0.32%+95,729+43.4%Added
TD Asset Management Inc319,924$58.0M0.06%−25,689−7.4%Reduced
Principal Financial Group Inc320,046$58.1M0.04%+4,658+1.5%Added
State Board of Administration of Florida Retirement System326,776$59.3M0.12%−7,864−2.3%Reduced
New York State Teachers Retirement System328,526$59.6M0.13%−13,108−3.8%Reduced
Acadian Asset Management LLC337,951$61.3M0.23%+88,374+35.4%Added
DekaBank Deutsche Girozentrale344,709$63.0M0.18%+8,784+2.6%Added
National Pension Service370,946$67.3M0.13%−1,100−0.3%Reduced
ProShare Advisors LLC373,152$67.7M0.19%+33,518+9.9%Added
Rhumbline Advisers385,274$69.9M0.09%−15,482−3.9%Reduced
Panagora Asset Management Inc389,888$70.7M0.38%+90,980+30.4%Added
Great West Life Assurance Co389,587$71.1M0.17%+1,011+0.3%Added
HSBC Holdings PLC401,059$72.9M0.08%+42,914+12.0%Added
Citadel Advisors LLC414,129$75.1M0.08%+24,539+6.3%Added
AXA S.A.421,889$76.5M0.21%+198,955+89.2%Added
Retirement Systems of Alabama435,067$78.9M0.30%+1,095+0.3%Added
Eaton Vance Management439,711$79.3M0.11%−250,320−36.3%Reduced
Raymond James & Associates439,481$79.7M0.07%+131,559+42.7%Added
Ensign Peak Advisors, Inc447,212$81.1M0.17%−158,321−26.1%Reduced
California State Teachers Retirement System448,582$81.4M0.10%−9,144−2.0%Reduced
Marshall Wace North America L.P.451,406$81.9M0.35%−128,419−22.1%Reduced
Jacobs Levy Equity Management, Inc457,122$82.9M0.56%−172,787−27.4%Reduced
Artisan Partners Limited Partnership465,031$84.4M0.10%−1,078−0.2%Reduced
Public Employees Retirement Association of Colorado469,107$85.1M0.37%−5,716−1.2%Reduced
Bank of Nova Scotia488,459$88.6M0.16%+447,537+1,093.6%Added
First Trust Advisors LP490,671$89.0M0.10%+91,357+22.9%Added
UBS Group AG502,848$91.2M0.04%+54,804+12.2%Added
New York State Common Retirement Fund503,383$91.3M0.10%+6,248+1.3%Added
DnB Asset Management AS509,902$92.5M0.60%+86,593+20.5%Added
Putnam Investments LLC519,039$94.1M0.15%−11,020−2.1%Reduced
Standard Life Aberdeen plc514,839$94.3M0.21%−12,600−2.4%Reduced
Voloridge Investment Management, LLC536,896$97.4M0.63%+284,222+112.5%Added
Susquehanna International Group, LLP550,229$99.8M0.13%+46,682+9.3%Added
Marshall Wace, LLP556,678$101.0M0.50%+5,719+1.0%Added
Barclays PLC568,703$103.2M0.07%+147,497+35.0%Added
Citigroup Inc579,609$105.1M0.11%−120,472−17.2%Reduced
Candriam Luxembourg S.C.A.592,829$107.5M0.73%−215,038−26.6%Reduced
Manufacturers Life Insurance Company, The592,967$107.6M0.09%−5,773−1.0%Reduced
Credit Suisse AG607,131$110.1M0.09%−72,085−10.6%Reduced
Natixis Advisors, L.P.616,708$111.9M0.46%+407,937+195.4%Added
Parnassus Investments619,438$112.4M0.24%00.0%Unchanged
Prudential Financial Inc610,778$114.1M0.16%+177,000+40.8%Added
Armistice Capital, LLC636,000$115.4M2.85%+36,000+6.0%Added
AQR Capital Management LLC639,317$116.0M0.21%−67,436−9.5%Reduced
Swedbank AB655,196$118.8M0.22%+43,410+7.1%Added
Avoro Capital Advisors LLC664,000$120.4M1.89%−126,000−15.9%Reduced
Allianz Asset Management GmbH669,444$121.4M0.10%+153,686+29.8%Added
Amundi689,898$125.1M0.09%+16,172+2.4%Added
Millennium Management LLC695,708$126.2M0.17%+331,296+90.9%Added
Dimensional Fund Advisors LP704,546$127.8M0.04%+185,523+35.7%Added
Parametric Portfolio Associates LLC734,985$133.3M0.08%−29,306−3.8%Reduced
American Century Companies Inc769,506$139.6M0.10%−130,754−14.5%Reduced
Royal Bank of Canada780,590$141.6M0.04%−291,551−27.2%Reduced
Two Sigma Advisers, LP782,700$142.0M0.37%+781,700+78,170.0%Added
Jennison Associates LLC829,359$150.4M0.10%+37,531+4.7%Added
Franklin Resources Inc866,924$157.3M0.06%−251,473−22.5%Reduced
Manning & Napier Group, LLC872,928$158.3M1.36%−24,153−2.7%Reduced
OrbiMed Advisors LLC877,400$159.2M1.77%−188,000−17.6%Reduced
Avidity Partners Management LP926,400$168.0M4.28%−23,600−2.5%Reduced
Two Sigma Investments, LP959,684$174.1M0.47%+959,684New
Swiss National Bank1,023,675$185.7M0.12%−36,300−3.4%Reduced
Morgan Stanley1,042,513$189.1M0.03%−178,813−14.6%Reduced
Bank of Montreal1,053,359$192.0M0.10%+114,535+12.2%Added
APG Asset Management N.V.1,228,689$192.3M0.34%−46,900−3.7%Reduced
Pictet Asset Management SA1,064,822$193.1M0.21%+1,064,822New
Impax Asset Management Group plc1,074,736$194.9M0.80%+319,209+42.2%Added
Sumitomo Mitsui Trust Holdings, Inc.1,092,041$198.1M0.12%−26,817−2.4%Reduced
Wells Fargo & Company1,131,591$205.3M0.05%−41,789−3.6%Reduced
Man Group plc1,211,443$219.7M0.78%+371,319+44.2%Added
Invesco Ltd.1,214,493$220.3M0.06%+48,410+4.2%Added