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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Puma Biotechnology, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
102
−14 vs. Q3 2021
Shares held
30.6M
−1.56M (−4.9%) vs. Q3 2021
Total value
$93.1M
−$132.9M (−58.8%) vs. Q3 2021
New holders
20
38 more added
Sold out
34
34 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 102 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ4 2021: $93.1M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q3 2021.

Institutions holding PBYI in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
BlackRock Inc.3,204,237$9.74M0.00%−3,424−0.1%Reduced
Vanguard Group Inc3,680,187$11.2M0.00%+50,754+1.4%Added
Fred Alger Management, LLC0$00.00%−2,470,965−100.0%Sold out
Palo Alto Investors LP0$00.00%−1,392,997−100.0%Sold out
Great Point Partners LLC0$00.00%−1,300,000−100.0%Sold out
AIGH Capital Management LLC0$00.00%−864,427−100.0%Sold out
Wellington Management Group LLP0$00.00%−550,700−100.0%Sold out
Worth Venture Partners, LLC0$00.00%−197,960−100.0%Sold out
Envestnet Asset Management Inc0$00.00%−135,226−100.0%Sold out
Truist Financial Corp0$00.00%−109,902−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−86,040−100.0%Sold out
Virginia Retirement Systems Et Al0$00.00%−85,600−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%–Sold out
Swiss National Bank0$00.00%−66,530−100.0%Sold out
Alps Advisors Inc0$00.00%−49,974−100.0%Sold out
Shell Asset Management Co0$00.00%−48,702−100.0%Sold out
Summit Global Investments0$00.00%−46,200−100.0%Sold out
Dimensional Fund Advisors LP0$00.00%−42,298−100.0%Sold out
UBS Asset Management Americas Inc0$00.00%−42,211−100.0%Sold out
Credit Suisse AG0$00.00%−38,765−100.0%Sold out
Capital Fund Management S.A.0$00.00%−36,706−100.0%Sold out
Oppenheimer Asset Management Inc.0$00.00%−29,815−100.0%Sold out
Trexquant Investment LP0$00.00%−27,735−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−20,400−100.0%Sold out
Two Sigma Investments, LP0$00.00%−15,920−100.0%Sold out
SG Americas Securities, LLC0$00.00%−15,091−100.0%Sold out
HighVista Strategies LLC0$00.00%−11,972−100.0%Sold out
Engineers Gate Manager LP0$00.00%−12,000−100.0%Sold out
Meeder Asset Management Inc0$00.00%−11,457−100.0%Sold out
Gyon Technologies Capital Management, LP0$00.00%−11,464−100.0%Sold out
LPL Financial LLC0$00.00%−10,420−100.0%Sold out
Public Employees Retirement Association of Colorado0$00.00%−7,106−100.0%Sold out
Great West Life Assurance Co0$00.00%−2,002−100.0%Sold out
O'Shaughnessy Asset Management, LLC0$00.00%−1,560−100.0%Sold out
Penserra Capital Management LLC0$00.00%−930−100.0%Sold out
Baillie Gifford & Co0$00.00%−252−100.0%Sold out