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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Puma Biotechnology, Inc. as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
116
+5 vs. Q4 2024
Shares held
30.4M
+953.1K (+3.2%) vs. Q4 2024
Total value
$90.1M
+$170.3K (+0.2%) vs. Q4 2024
New holders
25
44 more added
Sold out
20
25 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 116 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ1 2025: $90.1M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q4 2024.

Institutions holding PBYI in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Acorn Capital Advisors, LLC3,940,052$11.7M7.78%00.0%Unchanged
BlackRock, Inc.3,847,368$11.4M0.00%+23,563+0.6%Added
Vanguard Group Inc3,669,263$10.9M0.00%+25,841+0.7%Added
Acadian Asset Management LLC2,008,146$5.94M0.02%+36,018+1.8%Added
Renaissance Technologies LLC1,829,213$5.41M0.01%+73,700+4.2%Added
Millennium Management LLC1,385,194$4.10M0.00%−508,932−26.9%Reduced
American Century Companies Inc1,149,660$3.40M0.00%+201,284+21.2%Added
Geode Capital Management, LLC955,456$2.83M0.00%+36,021+3.9%Added
Kennedy Capital Management, Inc.911,123$2.70M0.06%+101,748+12.6%Added
Dimensional Fund Advisors LP888,663$2.63M0.00%+24,903+2.9%Added
Connor, Clark & Lunn Investment Management Ltd.831,689$2.46M0.01%+344,321+70.6%Added
State Street Corp649,792$1.92M0.00%+39,850+6.5%Added
D. E. Shaw & Co., Inc.571,665$1.69M0.00%+349,057+156.8%Added
Globeflex Capital L P452,606$1.34M0.12%00.0%Unchanged
Los Angeles Capital Management LLC406,854$1.20M0.01%+121,175+42.4%Added
Arrowstreet Capital, Limited Partnership358,621$1.06M0.00%+358,621New
SEI Investments Co347,679$1.03M0.00%+36,018+11.6%Added
Bank of New York Mellon Corp340,886$1.01M0.00%+9,033+2.7%Added
Northern Trust Corp317,438$939.6K0.00%−7,979−2.5%Reduced
Prudential Financial Inc308,155$912.1K0.00%+201,870+189.9%Added
Goldman Sachs Group Inc294,243$871.0K0.00%−19,854−6.3%Reduced
UBS Group AG279,667$827.8K0.00%+124,096+79.8%Added
Eversept Partners, LP275,788$816.3K0.09%−720,314−72.3%Reduced
Morgan Stanley262,538$777.1K0.00%−7,796−2.9%Reduced
Two Sigma Advisers, LP246,800$730.5K0.00%+49,900+25.3%Added
Marshall Wace, LLP216,413$640.6K0.00%+130,833+152.9%Added
Federated Hermes, Inc.200,962$594.8K0.00%+37,321+22.8%Added
Tang Capital Management LLC200,000$592.0K0.03%00.0%Unchanged
Two Sigma Investments, LP192,800$570.7K0.00%+11,329+6.2%Added
Prospera Financial Services Inc184,257$545.4K0.01%+6,362+3.6%Added
Mackenzie Financial Corp157,713$466.8K0.00%−78,246−33.2%Reduced
Qube Research & Technologies Ltd152,943$452.7K0.00%−35,181−18.7%Reduced
STRS Ohio141,900$420.0K0.00%−43,500−23.5%Reduced
FMR LLC127,174$376.4K0.00%−4,676−3.5%Reduced
XTX Topco Ltd125,317$370.9K0.02%+65,643+110.0%Added
Charles Schwab Investment Management Inc118,254$350.0K0.00%+588+0.5%Added
O'Shaughnessy Asset Management, LLC107,945$319.5K0.00%−4,626−4.1%Reduced
Gsa Capital Partners LLP99,394$294.0K0.03%−9,129−8.4%Reduced
Bank of America Corp93,087$275.5K0.00%+10,748+13.1%Added
Royal Bank of Canada85,999$254.0K0.00%+3,117+3.8%Added
Barclays PLC83,261$246.5K0.00%−5,146−5.8%Reduced
Bridgeway Capital Management, LLC81,100$240.1K0.01%−24,100−22.9%Reduced
Nuveen, LLC79,101$234.1K0.00%+79,101New
Franklin Resources Inc78,175$231.4K0.00%+61,588+371.3%Added
BNP Paribas Arbitrage, SA77,328$228.9K0.00%+3,027+4.1%Added
Susquehanna International Group, LLP72,871$215.7K0.00%−2,232−3.0%Reduced
Macquarie Group Ltd61,255$181.0K0.00%00.0%Unchanged
Integrated Quantitative Investments LLC59,727$176.8K0.09%−139−0.2%Reduced
Virtus ETF Advisers LLC55,431$164.1K0.11%+55,431New
LSV Asset Management53,400$158.0K0.00%00.0%Unchanged
AQR Capital Management LLC50,458$149.4K0.00%+39,641+366.5%Added
JPMorgan Chase & Co48,352$143.1K0.00%−88,545−64.7%Reduced
LPL Financial LLC43,293$128.1K0.00%+16,726+63.0%Added
Metis Global Partners, LLC42,758$126.6K0.00%+3,231+8.2%Added
Universal- Beteiligungs- und Servicegesellschaft mbH39,308$116.4K0.00%+39,308New
Rhumbline Advisers38,295$113.3K0.00%+40.0%Added
Prelude Capital Management, LLC37,700$111.6K0.01%+12,900+52.0%Added
Invesco Ltd.37,631$111.4K0.00%+17,707+88.9%Added
Man Group plc37,469$110.9K0.00%+37,469New
Virtu Financial LLC31,477$93.0K0.01%+31,477New
Deutsche Bank AG30,743$91.0K0.00%+30,743New
Intech Investment Management LLC30,504$90.3K0.00%+10,474+52.3%Added
Citigroup Inc29,467$87.2K0.00%−3,794−11.4%Reduced
MetLife Investment Management27,121$80.3K0.00%+27,121New
Mirae Asset Global ETFs Holdings Ltd.24,857$73.6K0.00%+1,092+4.6%Added
Voya Investment Management LLC24,732$73.2K0.00%+9,954+67.4%Added
Bailard, Inc.24,702$73.1K0.00%+24,702New
Wells Fargo & Company23,448$69.4K0.00%+519+2.3%Added
Dynamic Technology Lab Private Ltd22,030$66.0K0.01%+22,030New
Russell Investments Group, Ltd.20,893$61.8K0.00%+20,873+104,365.0%Added
Corebridge Financial, Inc.20,618$61.0K0.00%−306−1.5%Reduced
HSBC Holdings PLC20,509$60.5K0.00%+20,509New
PFG Investments, LLC20,000$59.2K0.00%+20,000New
Price T Rowe Associates Inc19,566$58.0K0.00%+483+2.5%Added
Royce & Associates LP18,725$55.4K0.00%00.0%Unchanged
Oxford Asset Management LLP17,647$52.2K0.02%−5,837−24.9%Reduced
Advisor Group Holdings, Inc.17,494$51.8K0.00%+16,851+2,620.7%Added
Manufacturers Life Insurance Company, The16,506$48.9K0.00%+16,506New
C2C Wealth Management, LLC15,150$44.8K0.04%+3,150+26.3%Added
Williams & Novak, LLC14,720$43.1K0.04%+14,720New
Causeway Capital Management LLC14,095$41.7K0.00%+14,095New
CAPROCK Group, Inc.13,817$40.9K0.00%+13,817New
Walleye Capital LLC13,055$38.6K0.00%−25,790−66.4%Reduced
Graham Capital Management, L.P.12,752$37.7K0.00%+2,020+18.8%Added
Quadrature Capital Ltd12,508$37.0K0.00%+12,508New
Sherbrooke Park Advisers LLC12,224$36.2K0.02%+12,224New
Patriot Financial Group Insurance Agency, LLC10,500$31.1K0.00%−1,500−12.5%Reduced
Gateway Wealth Partners, LLC10,200$30.2K0.01%00.0%Unchanged
Police & Firemen's Retirement System of New Jersey8,322$24.6K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.4,055$12.0K0.00%00.0%Unchanged
Legal & General Group Plc3,912$11.6K0.00%00.0%Unchanged
New York State Common Retirement Fund3,600$10.7K0.00%00.0%Unchanged
Ball & Co Wealth Management Inc.3,506$10.0K0.01%00.0%Unchanged
Tower Research Capital LLC (TRC)3,066$9.07K0.00%−7,071−69.8%Reduced
CWM, LLC3,012$9.00K0.00%+1,913+174.1%Added
California State Teachers Retirement System2,999$8.88K0.00%00.0%Unchanged
Lazard Asset Management LLC2,100$6.00K0.00%−395−15.8%Reduced
Private Wealth Asset Management, LLC2,000$5.92K0.00%+2,000New
Rialto Wealth Management, LLC1,450$4.29K0.00%+1,450New
Amalgamated Bank1,432$4.00K0.00%00.0%Unchanged