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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q1 2023

Institutional positions in Puma Biotechnology, Inc. as of Mar 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
78
−11 vs. Q4 2022
Shares held
27.9M
+360.1K (+1.3%) vs. Q4 2022
Total value
$86.3M
−$30.1M (−25.8%) vs. Q4 2022
New holders
10
29 more added
Sold out
21
19 more reduced

Compare with Q4 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2023: 78 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ1 2023: $86.3M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q1 2023

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q4 2022.

Institutions holding PBYI in Q1 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Camber Capital Management LP4,235,000$13.1M0.45%00.0%Unchanged
Vanguard Group Inc3,771,345$11.7M0.00%+182,423+5.1%Added
Millennium Management LLC2,985,835$9.23M0.01%+308,922+11.5%Added
Eversept Partners, LP1,938,088$5.99M0.54%+430,425+28.5%Added
Acadian Asset Management LLC1,874,859$5.79M0.03%+61,819+3.4%Added
Renaissance Technologies LLC1,834,913$5.67M0.01%+136,070+8.0%Added
Athyrium Capital Management, LP1,792,114$5.54M1.98%00.0%Unchanged
BlackRock Inc.1,518,942$4.69M0.00%−14,598−1.0%Reduced
Hillsdale Investment Management Inc.834,103$2.58M0.22%+167,897+25.2%Added
Globeflex Capital L P561,530$1.74M0.21%00.0%Unchanged
Kynam Capital Management, LP473,070$1.46M0.19%−88,539−15.8%Reduced
Susquehanna International Group, LLP462,196$1.43M0.00%+202,786+78.2%Added
Dimensional Fund Advisors LP453,105$1.40M0.00%+220,336+94.7%Added
Geode Capital Management, LLC391,622$1.21M0.00%+10,711+2.8%Added
Two Sigma Advisers, LP380,600$1.18M0.00%+105,200+38.2%Added
Rice Hall James & Associates, LLC367,497$1.14M0.06%−15,721−4.1%Reduced
Morgan Stanley339,895$1.05M0.00%−157,812−31.7%Reduced
SEI Investments Co286,060$883.9K0.00%−1050.0%Reduced
Citadel Advisors LLC236,375$730.4K0.00%+85,818+57.0%Added
Two Sigma Investments, LP208,149$643.2K0.00%−75,801−26.7%Reduced
LSV Asset Management194,551$601.0K0.00%−6,600−3.3%Reduced
Assenagon Asset Management S.A.193,194$597.0K0.00%+27,088+16.3%Added
Federated Hermes, Inc.191,063$590.4K0.00%−159,219−45.5%Reduced
State Street Corp188,599$582.8K0.00%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.183,945$568.4K0.00%+675+0.4%Added
Affinity Asset Advisors, LLC177,349$548.0K0.21%+177,349New
Marshall Wace, LLP173,816$537.1K0.00%−147,441−45.9%Reduced
Bridgeway Capital Management, LLC148,400$458.6K0.01%+28,300+23.6%Added
Cubist Systematic Strategies, LLC138,178$427.0K0.00%+62,740+83.2%Added
FMR LLC127,842$395.0K0.00%+63,933+100.0%Added
Cornercap Investment Counsel Inc124,919$386.0K0.07%+124,919New
Prospera Financial Services Inc100,072$309.2K0.01%+11,750+13.3%Added
XTX Topco Ltd81,619$252.2K0.05%−12,736−13.5%Reduced
Qube Research & Technologies Ltd76,685$237.0K0.00%+20,057+35.4%Added
Goldman Sachs Group Inc74,004$228.7K0.00%−2,447−3.2%Reduced
Bank of New York Mellon Corp73,363$226.7K0.00%+15,360+26.5%Added
Northern Trust Corp69,841$215.8K0.00%+3,405+5.1%Added
Man Group plc–$193.0K0.00%––
Macquarie Group Ltd61,255$189.0K0.00%00.0%Unchanged
Bank of America Corp53,153$164.2K0.00%+26,657+100.6%Added
683 Capital Management, LLC36,500$112.8K0.01%00.0%Unchanged
Patriot Financial Group Insurance Agency, LLC36,000$111.2K0.02%+7,500+26.3%Added
Jump Financial, LLC34,900$107.8K0.00%−11,934−25.5%Reduced
Crestline Management, LP31,884$98.5K0.01%+3,388+11.9%Added
Caxton Associates LP24,610$76.0K0.01%+24,610New
Franklin Resources Inc24,234$74.9K0.00%00.0%Unchanged
Boothbay Fund Management, LLC24,229$74.9K0.00%+4,011+19.8%Added
PDT Partners, LLC21,946$67.8K0.01%+2,800+14.6%Added
Walleye Capital LLC19,837$61.3K0.00%−29,355−59.7%Reduced
Charles Schwab Investment Management Inc19,453$60.1K0.00%00.0%Unchanged
Buckingham Strategic Partners19,220$59.4K0.00%00.0%Unchanged
Jane Street Group, LLC17,697$54.7K0.00%−23,121−56.6%Reduced
Barclays PLC17,298$53.5K0.00%00.0%Unchanged
Squarepoint Ops LLC16,850$52.1K0.00%−1,043−5.8%Reduced
Prudential Financial Inc16,400$50.7K0.00%+5,800+54.7%Added
Advisor Group Holdings, Inc.16,941$49.7K0.00%−489−2.8%Reduced
Bailard, Inc.14,102$43.6K0.00%−39,398−73.6%Reduced
Wolverine Trading, LLC12,944$37.0K0.00%+12,944New
Lighthouse Investment Partners, LLC11,276$34.8K0.00%+11,276New
Point72 Asset Management, L.P.11,000$34.0K0.00%+11,000New
UBS Group AG10,925$33.8K0.00%+7,485+217.6%Added
Commonwealth Equity Services, LLC10,749$33.0K0.00%−110−1.0%Reduced
Simplex Trading, LLC10,367$32.0K0.00%+10,367New
Tower Research Capital LLC (TRC)4,853$15.0K0.00%−9,897−67.1%Reduced
Group One Trading, L.P.3,733$11.5K0.00%+3,733New
Quantbot Technologies LP3,600$11.1K0.00%+3,600New
Lindbrook Capital, LLC2,793$8.63K0.00%00.0%Unchanged
GHP Investment Advisors, Inc.1,170$3.62K0.00%00.0%Unchanged
Geneos Wealth Management Inc.1,000$3.09K0.00%00.0%Unchanged
JPMorgan Chase & Co1,103$3.00K0.00%00.0%Unchanged
Aspire Private Capital, LLC700$2.16K0.00%00.0%Unchanged
Royal Bank of Canada385$1.00K0.00%+285+285.0%Added
Wells Fargo & Company272$8400.00%+5+1.9%Added
BNP Paribas Arbitrage, SA242$7480.00%00.0%Unchanged
US Bancorp200$6180.00%00.0%Unchanged
Tucker Asset Management LLC126$3890.00%+126New
The PNC Financial Services Group, Inc.123$3800.00%00.0%Unchanged
Cutler Group LP200$00.00%00.0%Unchanged
Brandywine Global Investment Management, LLC0$00.00%−318,601−100.0%Sold out
Armistice Capital, LLC0$00.00%−300,000−100.0%Sold out
EAM Investors, LLC0$00.00%−272,787−100.0%Sold out
D. E. Shaw & Co., Inc.0$00.00%−132,184−100.0%Sold out
Gsa Capital Partners LLP0$00.00%−72,940−100.0%Sold out
AlphaCentric Advisors LLC0$00.00%−50,000−100.0%Sold out
Virtu Financial LLC0$00.00%−49,760−100.0%Sold out
Bank of Montreal0$00.00%−32,265−100.0%Sold out
HRT Financial LP0$00.00%−30,416−100.0%Sold out
Citigroup Inc0$00.00%−26,473−100.0%Sold out
Acrisure Capital Management, LLC0$00.00%−25,409−100.0%Sold out
Occudo Quantitative Strategies LP0$00.00%−22,279−100.0%Sold out
Ergoteles LLC0$00.00%−19,300−100.0%Sold out
Bayesian Capital Management, LP0$00.00%−11,901−100.0%Sold out
Running Point Capital Advisors, LLC0$00.00%−10,000−100.0%Sold out
Freedom Wealth Alliance, LLC0$00.00%−1,721−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−1,675−100.0%Sold out
Money Concepts Capital Corp0$00.00%−1,000−100.0%Sold out
Crewe Advisors LLC0$00.00%−579−100.0%Sold out
Key Financial Inc0$00.00%−50−100.0%Sold out
Rockefeller Capital Management L.P.0$00.00%−14−100.0%Sold out