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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q1 2024

Institutional positions in Puma Biotechnology, Inc. as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
93
+11 vs. Q4 2023
Shares held
31.0M
+4.00M (+14.8%) vs. Q4 2023
Total value
$164.4M
+$47.4M (+40.5%) vs. Q4 2023
New holders
20
36 more added
Sold out
9
26 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 93 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ1 2024: $164.4M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q4 2023.

Institutions holding PBYI in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc3,491,249$18.5M0.00%−310,832−8.2%Reduced
Millennium Management LLC3,167,463$16.8M0.01%+3,214+0.1%Added
Frazier Life Sciences Management, L.P.2,816,294$14.9M0.63%+2,816,294New
Acadian Asset Management LLC1,956,513$10.4M0.04%+39,239+2.0%Added
Morgan Stanley1,852,806$9.82M0.00%+1,100,226+146.2%Added
Renaissance Technologies LLC1,729,413$9.17M0.01%+56,200+3.4%Added
Camber Capital Management LP1,650,000$8.74M0.31%−1,155,000−41.2%Reduced
BlackRock Inc.1,617,558$8.57M0.00%+73,026+4.7%Added
Eversept Partners, LP1,426,497$7.56M0.57%−268,524−15.8%Reduced
Great Point Partners LLC1,343,628$7.12M1.11%+250,355+22.9%Added
Athyrium Capital Management, LP1,256,411$6.66M9.15%−535,703−29.9%Reduced
Dimensional Fund Advisors LP568,293$3.01M0.00%+70,571+14.2%Added
Globeflex Capital L P491,751$2.61M0.25%−46,808−8.7%Reduced
Geode Capital Management, LLC452,971$2.40M0.00%+8,925+2.0%Added
Goldman Sachs Group Inc450,580$2.39M0.00%+334,625+288.6%Added
Jane Street Group, LLC429,251$2.28M0.00%+291,648+211.9%Added
Qube Research & Technologies Ltd387,178$2.05M0.00%+264,018+214.4%Added
Connor, Clark & Lunn Investment Management Ltd.385,863$2.05M0.01%+189,204+96.2%Added
Susquehanna International Group, LLP382,679$2.03M0.00%+235,121+159.3%Added
American Century Companies Inc372,249$1.97M0.00%+311,197+509.7%Added
SEI Investments Co289,677$1.54M0.00%−2,191−0.8%Reduced
Two Sigma Advisers, LP255,300$1.35M0.00%−29,500−10.4%Reduced
Marshall Wace, LLP238,491$1.26M0.00%−110,131−31.6%Reduced
Arrowstreet Capital, Limited Partnership230,425$1.22M0.00%+230,425New
Man Group plc211,682$1.12M0.00%+42,972+25.5%Added
Bank of New York Mellon Corp188,893$1.00M0.00%+142,460+306.8%Added
Winton Group Ltd188,283$997.9K0.07%+188,283New
Gsa Capital Partners LLP187,585$994.0K0.08%−74,752−28.5%Reduced
State Street Corp172,482$914.2K0.00%+10,000+6.2%Added
Wellington Management Group LLP170,765$905.1K0.00%+170,765New
Federated Hermes, Inc.160,924$852.9K0.00%−616−0.4%Reduced
Prospera Financial Services Inc147,792$783.3K0.02%+4,575+3.2%Added
Rice Hall James & Associates, LLC140,106$742.6K0.04%−189,764−57.5%Reduced
Bridgeway Capital Management, LLC139,400$738.8K0.02%+15,000+12.1%Added
Laurion Capital Management LP131,175$695.2K0.02%00.0%Unchanged
Citigroup Inc130,473$691.5K0.00%−40,580−23.7%Reduced
HRT Financial LP127,231$674.0K0.00%+127,231New
Bank of Montreal107,900$605.3K0.00%+26,500+32.6%Added
FMR LLC91,690$486.0K0.00%+35,616+63.5%Added
Cubist Systematic Strategies, LLC88,029$466.6K0.01%+52,641+148.8%Added
Northern Trust Corp83,537$442.7K0.00%−226−0.3%Reduced
Two Sigma Investments, LP81,694$433.0K0.00%−133,478−62.0%Reduced
O'Shaughnessy Asset Management, LLC77,081$408.5K0.00%+43,229+127.7%Added
Marathon Trading Investment Management LLC70,300$372.6K0.15%+70,300New
Assenagon Asset Management S.A.70,145$371.8K0.00%−14,894−17.5%Reduced
EntryPoint Capital, LLC61,991$328.6K0.29%+61,991New
Macquarie Group Ltd62,784$325.0K0.00%+1,529+2.5%Added
Squarepoint Ops LLC60,634$321.4K0.00%+32,236+113.5%Added
JPMorgan Chase & Co60,404$320.1K0.00%+6,016+11.1%Added
XTX Topco Ltd54,153$287.0K0.04%−739−1.3%Reduced
Brevan Howard Capital Management LP49,875$264.3K0.02%+49,875New
Lazard Asset Management LLC49,466$262.0K0.00%+48,520+5,129.0%Added
Schonfeld Strategic Advisors LLC46,604$247.0K0.00%+26,545+132.3%Added
Jump Financial, LLC41,658$220.8K0.01%−15,542−27.2%Reduced
Metis Global Partners, LLC39,527$209.5K0.01%+39,527New
Point72 Asia (Singapore) Pte. Ltd.38,346$203.2K0.05%+37,450+4,179.7%Added
Ritholtz Wealth Management37,324$197.8K0.01%+22,146+145.9%Added
Crestline Management, LP35,832$189.9K0.02%+1,058+3.0%Added
Balyasny Asset Management LLC32,709$173.4K0.00%−48,943−59.9%Reduced
Trexquant Investment LP32,199$170.7K0.00%+32,199New
LSV Asset Management30,400$161.0K0.00%−56,251−64.9%Reduced
LPL Financial LLC20,677$109.6K0.00%+9,754+89.3%Added
Charles Schwab Investment Management Inc19,453$103.1K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd19,383$102.7K0.01%+1,437+8.0%Added
Buckingham Strategic Partners19,220$101.9K0.00%00.0%Unchanged
Barclays PLC17,324$91.8K0.00%00.0%Unchanged
Omers Administration Corp16,800$89.0K0.00%+16,800New
ExodusPoint Capital Management, LP15,627$83.0K0.00%−37,613−70.6%Reduced
Bank of America Corp15,219$80.7K0.00%−112,716−88.1%Reduced
Prudential Financial Inc15,200$80.6K0.00%−1,200−7.3%Reduced
CTC Alternative Strategies, Ltd.12,100$64.1K0.04%+12,100New
Royce & Associates LP11,738$62.2K0.00%+11,738New
Patriot Financial Group Insurance Agency, LLC11,500$61.0K0.01%−23,000−66.7%Reduced
LMR Partners LLP11,006$58.3K0.00%+11,006New
Commonwealth Equity Services, LLC10,790$57.0K0.00%+41+0.4%Added
SG Americas Securities, LLC10,740$57.0K0.00%+10,740New
UBS Group AG10,643$56.4K0.00%−480−4.3%Reduced
Wells Fargo & Company8,316$44.1K0.00%+8,005+2,574.0%Added
State of Wyoming6,650$35.2K0.01%+6,650New
Headlands Technologies LLC2,301$12.2K0.00%+2,301New
Rhumbline Advisers2,086$11.1K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,692$8.97K0.00%−1,110−39.6%Reduced
Group One Trading, L.P.1,495$7.92K0.00%+1,495New
GHP Investment Advisors, Inc.1,170$6.20K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC1,000$5.30K0.00%00.0%Unchanged
Simplex Trading, LLC947$5.00K0.00%−4,858−83.7%Reduced
CIBC Private Wealth Group, LLC775$4.09K0.00%+775New
GWM Advisors LLC717$3.80K0.00%+717New
Aspire Private Capital, LLC700$3.71K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.650$3.44K0.00%+300+85.7%Added
BNP Paribas Arbitrage, SA242$1.28K0.00%00.0%Unchanged
US Bancorp200$1.06K0.00%00.0%Unchanged
ZRC Wealth Management, LLC3$160.00%00.0%Unchanged
Affinity Asset Advisors, LLC0$00.00%−202,349−100.0%Sold out
Citadel Advisors LLC0$00.00%−121,796−100.0%Sold out
683 Capital Management, LLC0$00.00%−55,005−100.0%Sold out
Franklin Resources Inc0$00.00%−19,162−100.0%Sold out
Engineers Gate Manager LP0$00.00%−19,077−100.0%Sold out
Boothbay Fund Management, LLC0$00.00%−17,895−100.0%Sold out
Royal Bank of Canada0$00.00%−5,100−100.0%Sold out