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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Puma Biotechnology, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
82
+13 vs. Q3 2023
Shares held
27.0M
+1.31M (+5.1%) vs. Q3 2023
Total value
$117.0M
+$49.4M (+73.0%) vs. Q3 2023
New holders
19
29 more added
Sold out
6
15 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 82 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ4 2023: $117.0M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q3 2023.

Institutions holding PBYI in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Vanguard Group Inc3,802,081$16.5M0.00%+29,688+0.8%Added
Millennium Management LLC3,164,249$13.7M0.01%+80,900+2.6%Added
Camber Capital Management LP2,805,000$12.1M0.42%−1,430,000−33.8%Reduced
Acadian Asset Management LLC1,917,274$8.30M0.03%+59,274+3.2%Added
Athyrium Capital Management, LP1,792,114$7.76M11.27%00.0%Unchanged
Eversept Partners, LP1,695,021$7.34M0.72%+13,872+0.8%Added
Renaissance Technologies LLC1,673,213$7.25M0.01%−53,389−3.1%Reduced
BlackRock Inc.1,544,532$6.69M0.00%+68,821+4.7%Added
Great Point Partners LLC1,093,273$4.73M0.81%+1,093,273New
Morgan Stanley752,580$3.26M0.00%+413,759+122.1%Added
Globeflex Capital L P538,559$2.33M0.24%00.0%Unchanged
Dimensional Fund Advisors LP497,722$2.16M0.00%+18,211+3.8%Added
Geode Capital Management, LLC444,046$1.92M0.00%+18,531+4.4%Added
Marshall Wace, LLP348,622$1.51M0.00%+134,409+62.7%Added
Rice Hall James & Associates, LLC329,870$1.43M0.08%−33,796−9.3%Reduced
SEI Investments Co291,868$1.26M0.00%+6,211+2.2%Added
Two Sigma Advisers, LP284,800$1.23M0.00%+25,000+9.6%Added
Gsa Capital Partners LLP262,337$1.14M0.10%−17,292−6.2%Reduced
Two Sigma Investments, LP215,172$931.7K0.00%+107,434+99.7%Added
Affinity Asset Advisors, LLC202,349$876.2K0.17%00.0%Unchanged
Connor, Clark & Lunn Investment Management Ltd.196,659$851.5K0.00%−3,108−1.6%Reduced
Citigroup Inc171,053$740.7K0.00%+71,286+71.5%Added
Man Group plc168,710$730.5K0.00%+168,710New
State Street Corp162,482$703.5K0.00%00.0%Unchanged
Federated Hermes, Inc.161,540$699.5K0.00%−20,401−11.2%Reduced
Susquehanna International Group, LLP147,558$638.9K0.00%+49,536+50.5%Added
Prospera Financial Services Inc143,217$620.1K0.02%+20,325+16.5%Added
Jane Street Group, LLC137,603$595.8K0.00%+137,603New
Laurion Capital Management LP131,175$568.0K0.02%+131,175New
Bank of America Corp127,935$554.0K0.00%+104,614+448.6%Added
Bridgeway Capital Management, LLC124,400$538.7K0.01%−24,000−16.2%Reduced
Qube Research & Technologies Ltd123,160$533.3K0.00%+114,810+1,375.0%Added
Citadel Advisors LLC121,796$527.4K0.00%−58,317−32.4%Reduced
Goldman Sachs Group Inc115,955$502.1K0.00%+31,811+37.8%Added
LSV Asset Management86,651$375.0K0.00%00.0%Unchanged
Assenagon Asset Management S.A.85,039$368.2K0.00%+15,897+23.0%Added
Northern Trust Corp83,763$362.7K0.00%+14,311+20.6%Added
Bank of Montreal81,400$357.3K0.00%+81,400New
Balyasny Asset Management LLC81,652$353.6K0.00%+81,652New
Macquarie Group Ltd61,255$265.0K0.00%00.0%Unchanged
American Century Companies Inc61,052$264.4K0.00%+61,052New
Jump Financial, LLC57,200$247.7K0.01%+32,510+131.7%Added
FMR LLC56,074$242.8K0.00%−8,305−12.9%Reduced
683 Capital Management, LLC55,005$238.2K0.02%+55,005New
XTX Topco Ltd54,892$237.7K0.05%+39,603+259.0%Added
JPMorgan Chase & Co54,388$235.5K0.00%+54,329+92,083.1%Added
ExodusPoint Capital Management, LP53,240$231.0K0.00%+53,240New
Bank of New York Mellon Corp46,433$201.1K0.00%−6,490−12.3%Reduced
Cubist Systematic Strategies, LLC35,388$153.2K0.00%−1,529−4.1%Reduced
Crestline Management, LP34,774$150.6K0.01%+2,135+6.5%Added
Patriot Financial Group Insurance Agency, LLC34,500$149.4K0.03%−32,500−48.5%Reduced
O'Shaughnessy Asset Management, LLC33,852$146.6K0.00%+33,852New
Squarepoint Ops LLC28,398$123.0K0.00%−28,180−49.8%Reduced
Schonfeld Strategic Advisors LLC20,059$86.9K0.00%+20,059New
Charles Schwab Investment Management Inc19,453$84.2K0.00%00.0%Unchanged
Buckingham Strategic Partners19,220$83.2K0.00%00.0%Unchanged
Franklin Resources Inc19,162$83.0K0.00%00.0%Unchanged
Engineers Gate Manager LP19,077$82.6K0.00%+19,077New
Y-Intercept (Hong Kong) Ltd17,946$77.7K0.01%+17,946New
Boothbay Fund Management, LLC17,895$77.5K0.00%+17,895New
Barclays PLC17,324$75.0K0.00%−1,961−10.2%Reduced
Prudential Financial Inc16,400$71.0K0.00%00.0%Unchanged
Ritholtz Wealth Management15,178$65.7K0.00%+15,178New
UBS Group AG11,123$48.2K0.00%+7,717+226.6%Added
LPL Financial LLC10,923$47.3K0.00%+10,923New
Commonwealth Equity Services, LLC10,749$47.0K0.00%00.0%Unchanged
Simplex Trading, LLC5,805$25.0K0.00%+5,048+666.8%Added
Royal Bank of Canada5,100$22.0K0.00%+3,285+181.0%Added
Tower Research Capital LLC (TRC)2,802$12.1K0.00%−1,629−36.8%Reduced
Lindbrook Capital, LLC2,793$12.1K0.00%00.0%Unchanged
Rhumbline Advisers2,086$9.03K0.00%00.0%Unchanged
GHP Investment Advisors, Inc.1,170$5.07K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC1,000$4.33K0.00%+1,000New
Lazard Asset Management LLC946$4.00K0.00%+946New
Point72 Asia (Singapore) Pte. Ltd.896$3.88K0.00%+896New
Aspire Private Capital, LLC700$3.03K0.00%00.0%Unchanged
Advisor Group Holdings, Inc.350$1.52K0.00%+200+133.3%Added
Wells Fargo & Company311$1.35K0.00%+16+5.4%Added
BNP Paribas Arbitrage, SA242$1.05K0.00%00.0%Unchanged
US Bancorp200$8660.00%00.0%Unchanged
JNBA Financial Advisors4$180.00%00.0%Unchanged
ZRC Wealth Management, LLC3$80.00%00.0%Unchanged
Kynam Capital Management, LP0$00.00%−473,975−100.0%Sold out
Hillsdale Investment Management Inc.0$00.00%−27,276−100.0%Sold out
Virtu Financial LLC0$00.00%−14,262−100.0%Sold out
Geneos Wealth Management Inc.0$00.00%−1,000−100.0%Sold out
Headlands Technologies LLC0$00.00%−192−100.0%Sold out
Cutler Group LP0$00.00%−200−100.0%Sold out