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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q3 2022

Institutional positions in Puma Biotechnology, Inc. as of Sep 30, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
83
−6 vs. Q2 2022
Shares held
27.7M
−232.9K (−0.8%) vs. Q2 2022
Total value
$65.5M
−$14.0M (−17.6%) vs. Q2 2022
New holders
8
21 more added
Sold out
14
29 more reduced

Compare with Q2 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2022: 83 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ3 2022: $65.5M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q3 2022

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q2 2022.

Institutions holding PBYI in Q3 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Camber Capital Management LP4,235,000$10.0M0.34%00.0%Unchanged
Vanguard Group Inc3,623,629$8.59M0.00%−7,800−0.2%Reduced
Millennium Management LLC2,792,549$6.62M0.01%+575,905+26.0%Added
BlackRock Inc.1,862,167$4.41M0.00%−40,970−2.2%Reduced
Acadian Asset Management LLC1,838,942$4.35M0.02%+30,114+1.7%Added
Renaissance Technologies LLC1,799,662$4.26M0.01%−177,273−9.0%Reduced
Athyrium Capital Management, LP1,792,114$4.25M1.59%00.0%Unchanged
Eversept Partners, LP1,505,705$3.57M0.42%+70,628+4.9%Added
Armistice Capital, LLC1,000,000$2.37M0.06%−500,000−33.3%Reduced
Globeflex Capital L P570,840$1.35M0.23%+151,518+36.1%Added
Kynam Capital Management, LP559,769$1.33M0.28%−20,146−3.5%Reduced
D. E. Shaw & Co., Inc.538,544$1.28M0.00%−421,528−43.9%Reduced
AlphaCentric Advisors LLC415,000$984.0K1.01%+415,000New
Morgan Stanley391,522$928.0K0.00%−24,942−6.0%Reduced
Rice Hall James & Associates, LLC387,539$918.0K0.05%−118,527−23.4%Reduced
Geode Capital Management, LLC374,666$887.0K0.00%+4,575+1.2%Added
Federated Hermes, Inc.355,368$842.0K0.00%+4,251+1.2%Added
Brandywine Global Investment Management, LLC318,601$755.0K0.01%−11,899−3.6%Reduced
SEI Investments Co285,251$676.0K0.00%+1,311+0.5%Added
Citadel Advisors LLC209,965$497.0K0.00%−89,512−29.9%Reduced
Two Sigma Advisers, LP186,600$442.0K0.00%+45,600+32.3%Added
LSV Asset Management182,099$432.0K0.00%+182,099New
State Street Corp181,703$431.0K0.00%00.0%Unchanged
Assenagon Asset Management S.A.166,106$394.0K0.00%−21,384−11.4%Reduced
Connor, Clark & Lunn Investment Management Ltd.149,294$354.0K0.00%+71,703+92.4%Added
Susquehanna International Group, LLP143,925$341.0K0.00%+23,501+19.5%Added
Gsa Capital Partners LLP140,321$333.0K0.04%+71,572+104.1%Added
Bridgeway Capital Management, LLC126,100$299.0K0.01%00.0%Unchanged
Ergoteles LLC122,609$291.0K0.01%−20,491−14.3%Reduced
Goldman Sachs Group Inc119,532$284.0K0.00%−101,360−45.9%Reduced
Russell Investments Group, Ltd.99,139$234.0K0.00%−20,960−17.5%Reduced
Two Sigma Investments, LP83,607$198.0K0.00%−70,597−45.8%Reduced
Prospera Financial Services Inc82,247$195.0K0.01%+8,823+12.0%Added
Northern Trust Corp68,951$163.0K0.00%−35−0.1%Reduced
FMR LLC64,311$152.0K0.00%−434−0.7%Reduced
Ally Bridge Group (NY) LLC64,295$152.0K0.10%+64,295New
Macquarie Group Ltd61,255$145.0K0.00%00.0%Unchanged
Bank of America Corp60,677$143.0K0.00%−9,020−12.9%Reduced
Dimensional Fund Advisors LP57,305$136.0K0.00%+57,305New
Barclays PLC54,110$129.0K0.00%−2,956−5.2%Reduced
Bailard, Inc.53,500$127.0K0.01%00.0%Unchanged
Patriot Financial Group Insurance Agency, LLC50,500$120.0K0.03%−5,000−9.0%Reduced
Price T Rowe Associates Inc45,400$108.0K0.00%00.0%Unchanged
Bank of New York Mellon Corp30,033$71.0K0.00%−2,019−6.3%Reduced
Crestline Management, LP28,205$67.0K0.01%00.0%Unchanged
XTX Topco Ltd28,056$66.0K0.02%−8,074−22.3%Reduced
Qube Research & Technologies Ltd26,545$63.0K0.00%−2,765−9.4%Reduced
Atria Wealth Solutions, Inc.25,200$59.7K0.00%−10,000−28.4%Reduced
Cubist Systematic Strategies, LLC24,136$57.0K0.00%−45,802−65.5%Reduced
Franklin Resources Inc24,234$57.0K0.00%+251+1.0%Added
Diversified Trust Co20,175$48.0K0.00%00.0%Unchanged
Man Group plc20,181$48.0K0.00%––
BNP Paribas Arbitrage, SA19,918$47.2K0.00%+6,212+45.3%Added
Buckingham Strategic Partners19,220$46.0K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)19,360$46.0K0.00%+1,427+8.0%Added
HSBC Holdings PLC18,913$45.0K0.00%−4,371−18.8%Reduced
Walleye Capital LLC18,283$43.0K0.00%−85,940−82.5%Reduced
Advisor Group Holdings, Inc.17,482$42.0K0.00%+2,502+16.7%Added
Simplex Trading, LLC15,946$37.0K0.00%+12,483+360.5%Added
Cambridge Investment Research Advisors, Inc.14,945$35.0K0.00%+14,945New
Balyasny Asset Management LLC13,851$33.0K0.00%+13,851New
LMR Partners LLP11,514$27.0K0.00%00.0%Unchanged
Running Point Capital Advisors, LLC10,000$24.0K0.02%00.0%Unchanged
Leonteq Securities AG6,000$14.2K0.00%+1,000+20.0%Added
Quantbot Technologies LP4,489$10.0K0.00%+1,820+68.2%Added
UBS Group AG3,425$8.00K0.00%−1,114−24.5%Reduced
Lindbrook Capital, LLC2,793$7.00K0.00%00.0%Unchanged
JPMorgan Chase & Co2,849$7.00K0.00%+617+27.6%Added
GHP Investment Advisors, Inc.1,170$3.00K0.00%00.0%Unchanged
Money Concepts Capital Corp1,000$2.00K0.00%00.0%Unchanged
Geneos Wealth Management Inc.1,000$2.00K0.00%00.0%Unchanged
Aspire Private Capital, LLC700$2.00K0.00%00.0%Unchanged
Citigroup Inc548$1.00K0.00%−429−43.9%Reduced
Crewe Advisors LLC579$1.00K0.00%00.0%Unchanged
Wells Fargo & Company260$1.00K0.00%+7+2.8%Added
China Universal Asset Management Co., Ltd.426$1.00K0.00%+426New
US Bancorp200$00.00%00.0%Unchanged
The PNC Financial Services Group, Inc.123$00.00%00.0%Unchanged
Daiwa Securities Group Inc.87$00.00%00.0%Unchanged
Cutler Group LP200$00.00%00.0%Unchanged
Rockefeller Capital Management L.P.275$00.00%00.0%Unchanged
Quent Capital, LLC143$00.00%00.0%Unchanged
Key Financial Inc50$00.00%+50New
Voya Investment Management LLC0$00.00%−92,237−100.0%Sold out
Algert Global LLC0$00.00%−48,178−100.0%Sold out
Charles Schwab Investment Management Inc0$00.00%−28,820−100.0%Sold out
State of Wyoming0$00.00%−20,732−100.0%Sold out
HRT Financial LP0$00.00%−18,035−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−14,156−100.0%Sold out
Jane Street Group, LLC0$00.00%−11,076−100.0%Sold out
Mackenzie Financial Corp0$00.00%−10,090−100.0%Sold out
Gladius Capital Management LP0$00.00%−9,811−100.0%Sold out
Eagle Bay Advisors LLC0$00.00%−6,500−100.0%Sold out
Captrust Financial Advisors0$00.00%−1,500−100.0%Sold out
New York State Common Retirement Fund0$00.00%−252−100.0%Sold out
Credit Suisse AG0$00.00%−17−100.0%Sold out
Ellevest, Inc.0$00.00%−94−100.0%Sold out