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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Puma Biotechnology, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
121
+6 vs. Q1 2025
Shares held
32.9M
+2.48M (+8.1%) vs. Q1 2025
Total value
$112.8M
+$22.8M (+25.3%) vs. Q1 2025
New holders
22
42 more added
Sold out
16
32 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 121 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ2 2025: $112.8M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q1 2025.

Institutions holding PBYI in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Acorn Capital Advisors, LLC4,131,299$14.2M9.27%+191,247+4.9%Added
BlackRock, Inc.3,835,715$13.2M0.00%−11,653−0.3%Reduced
Vanguard Group Inc3,706,452$12.7M0.00%+37,189+1.0%Added
Acadian Asset Management LLC2,008,146$6.88M0.01%00.0%Unchanged
Renaissance Technologies LLC1,874,713$6.43M0.01%+45,500+2.5%Added
American Century Companies Inc1,342,275$4.60M0.00%+192,615+16.8%Added
Dimensional Fund Advisors LP1,150,040$3.94M0.00%+261,377+29.4%Added
Kennedy Capital Management, Inc.987,001$3.39M0.08%+75,878+8.3%Added
Geode Capital Management, LLC971,674$3.33M0.00%+16,218+1.7%Added
Connor, Clark & Lunn Investment Management Ltd.900,256$3.09M0.01%+68,567+8.2%Added
Janus Henderson Group PLC745,541$2.56M0.00%+745,541New
State Street Corp734,606$2.52M0.00%+84,814+13.1%Added
D. E. Shaw & Co., Inc.640,780$2.20M0.00%+69,115+12.1%Added
LSV Asset Management535,740$1.84M0.00%+482,340+903.3%Added
Citadel Advisors LLC507,818$1.74M0.00%+507,818New
Globeflex Capital L P452,606$1.55M0.13%00.0%Unchanged
Arrowstreet Capital, Limited Partnership451,633$1.55M0.00%+93,012+25.9%Added
Los Angeles Capital Management LLC445,477$1.53M0.01%+38,623+9.5%Added
O'Shaughnessy Asset Management, LLC437,660$1.50M0.01%+329,715+305.4%Added
SEI Investments Co347,234$1.19M0.00%−445−0.1%Reduced
Bank of New York Mellon Corp344,083$1.18M0.00%+3,197+0.9%Added
Millennium Management LLC334,609$1.15M0.00%−1,050,585−75.8%Reduced
Morgan Stanley322,462$1.11M0.00%+59,924+22.8%Added
Northern Trust Corp302,015$1.04M0.00%−15,423−4.9%Reduced
Prudential Financial Inc281,244$964.7K0.00%−26,911−8.7%Reduced
UBS Group AG274,100$940.2K0.00%−5,567−2.0%Reduced
Two Sigma Advisers, LP245,700$842.8K0.00%−1,100−0.4%Reduced
Eversept Partners, LP240,688$825.6K0.08%−35,100−12.7%Reduced
Mackenzie Financial Corp207,591$712.0K0.00%+49,878+31.6%Added
Bridgeway Capital Management, LLC202,790$695.6K0.02%+121,690+150.0%Added
Federated Hermes, Inc.202,335$694.0K0.00%+1,373+0.7%Added
Goldman Sachs Group Inc202,029$693.0K0.00%−92,214−31.3%Reduced
Tang Capital Management LLC200,000$686.0K0.03%00.0%Unchanged
Ritholtz Wealth Management196,985$675.7K0.01%+196,985New
Prospera Financial Services Inc191,244$655.9K0.01%+6,987+3.8%Added
Two Sigma Investments, LP190,621$653.8K0.00%−2,179−1.1%Reduced
Royal Bank of Canada153,270$524.0K0.00%+67,271+78.2%Added
STRS Ohio147,300$505.2K0.00%+5,400+3.8%Added
AQR Capital Management LLC141,773$486.3K0.00%+91,315+181.0%Added
Qube Research & Technologies Ltd137,079$470.2K0.00%−15,864−10.4%Reduced
FMR LLC132,364$454.0K0.00%+5,190+4.1%Added
Charles Schwab Investment Management Inc127,443$437.1K0.00%+9,189+7.8%Added
Barclays PLC108,653$372.7K0.00%+25,392+30.5%Added
XTX Topco Ltd104,424$358.2K0.01%−20,893−16.7%Reduced
Evergreen Capital Management LLC96,000$329.3K0.01%+96,000New
Hillsdale Investment Management Inc.84,800$290.9K0.01%+84,800New
Nuveen, LLC79,101$271.3K0.00%00.0%Unchanged
Panagora Asset Management Inc76,684$263.0K0.00%+76,684New
Marshall Wace, LLP73,415$251.8K0.00%−142,998−66.1%Reduced
State Board of Administration of Florida Retirement System71,727$246.0K0.00%+71,727New
Kapitalo Investimentos Ltda70,269$241.0K0.05%+70,269New
Bank of America Corp67,242$230.6K0.00%−25,845−27.8%Reduced
Macquarie Group Ltd61,255$210.0K0.00%00.0%Unchanged
Rhumbline Advisers60,611$207.9K0.00%+22,316+58.3%Added
Susquehanna International Group, LLP57,724$198.0K0.00%−15,147−20.8%Reduced
Metis Global Partners, LLC55,798$191.4K0.00%+13,040+30.5%Added
Virtus ETF Advisers LLC55,431$190.1K0.12%00.0%Unchanged
LPL Financial LLC53,293$182.8K0.00%+10,000+23.1%Added
Invesco Ltd.49,982$171.4K0.00%+12,351+32.8%Added
Jane Street Group, LLC39,448$135.3K0.00%+39,448New
Universal- Beteiligungs- und Servicegesellschaft mbH39,308$134.8K0.00%00.0%Unchanged
Empowered Funds, LLC38,292$131.3K0.00%+38,292New
Prelude Capital Management, LLC33,422$114.6K0.01%−4,278−11.3%Reduced
Deutsche Bank AG30,743$105.4K0.00%00.0%Unchanged
Wells Fargo & Company28,026$96.1K0.00%+4,578+19.5%Added
MetLife Investment Management27,158$93.2K0.00%+37+0.1%Added
Mirae Asset Global ETFs Holdings Ltd.23,765$81.5K0.00%−1,092−4.4%Reduced
Intech Investment Management LLC20,823$71.4K0.00%−9,681−31.7%Reduced
C2C Wealth Management, LLC20,620$70.7K0.06%+5,470+36.1%Added
JPMorgan Chase & Co20,245$69.4K0.00%−28,107−58.1%Reduced
Kathmere Capital Management, LLC20,204$69.3K0.01%+20,204New
PFG Investments, LLC20,000$68.6K0.00%00.0%Unchanged
Price T Rowe Associates Inc19,566$68.0K0.00%00.0%Unchanged
HSBC Holdings PLC19,751$66.6K0.00%−758−3.7%Reduced
Advisor Group Holdings, Inc.17,944$61.5K0.00%+450+2.6%Added
Squarepoint Ops LLC17,794$61.0K0.00%+17,794New
Franklin Resources Inc17,691$60.7K0.00%−60,484−77.4%Reduced
Royce & Associates LP17,285$59.3K0.00%−1,440−7.7%Reduced
Manufacturers Life Insurance Company, The15,576$53.4K0.00%−930−5.6%Reduced
D'Orazio & Associates, Inc.15,027$51.5K0.01%+15,027New
Ethic Inc.15,168$50.5K0.00%+15,168New
Citigroup Inc14,320$49.1K0.00%−15,147−51.4%Reduced
Ieq Capital, LLC14,305$49.1K0.00%+14,305New
Causeway Capital Management LLC14,095$48.3K0.00%00.0%Unchanged
Alliancebernstein L.P.13,800$47.3K0.00%+13,800New
Voya Investment Management LLC12,976$44.5K0.00%−11,756−47.5%Reduced
Williams & Novak, LLC12,520$42.9K0.04%−2,200−14.9%Reduced
Cerity Partners LLC10,528$36.1K0.00%+10,528New
CWM, LLC9,462$32.0K0.00%+6,450+214.1%Added
Tower Research Capital LLC (TRC)8,469$29.0K0.00%+5,403+176.2%Added
Police & Firemen's Retirement System of New Jersey8,322$28.5K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA5,766$19.8K0.00%−71,562−92.5%Reduced
Ameritas Investment Partners, Inc.4,055$13.9K0.00%00.0%Unchanged
New York State Common Retirement Fund3,600$12.3K0.00%00.0%Unchanged
Legal & General Group Plc3,564$12.2K0.00%−348−8.9%Reduced
Private Wealth Asset Management, LLC3,500$12.0K0.00%+1,500+75.0%Added
Ball & Co Wealth Management Inc.3,506$12.0K0.01%00.0%Unchanged
California State Teachers Retirement System2,999$10.3K0.00%00.0%Unchanged
Headlands Technologies LLC1,538$5.28K0.00%+321+26.4%Added
Global Retirement Partners, LLC1,492$5.12K0.00%+1,492New