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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Puma Biotechnology, Inc. as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
89
+6 vs. Q3 2022
Shares held
27.5M
−156.0K (−0.6%) vs. Q3 2022
Total value
$116.3M
+$50.8M (+77.5%) vs. Q3 2022
New holders
21
23 more added
Sold out
15
26 more reduced

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 89 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ4 2022: $116.3M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q3 2022.

Institutions holding PBYI in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Camber Capital Management LP4,235,000$17.9M0.63%00.0%Unchanged
Vanguard Group Inc3,588,922$15.2M0.00%−34,707−1.0%Reduced
Millennium Management LLC2,676,913$11.3M0.01%−115,636−4.1%Reduced
Acadian Asset Management LLC1,813,040$7.67M0.04%−25,902−1.4%Reduced
Athyrium Capital Management, LP1,792,114$7.58M3.19%00.0%Unchanged
Renaissance Technologies LLC1,698,843$7.19M0.01%−100,819−5.6%Reduced
BlackRock Inc.1,533,540$6.49M0.00%−328,627−17.6%Reduced
Eversept Partners, LP1,507,663$6.38M0.61%+1,958+0.1%Added
Hillsdale Investment Management Inc.666,206$2.82M0.24%+666,206New
Kynam Capital Management, LP561,609$2.38M0.36%+1,840+0.3%Added
Globeflex Capital L P561,530$2.38M0.30%−9,310−1.6%Reduced
Morgan Stanley497,707$2.11M0.00%+106,185+27.1%Added
Rice Hall James & Associates, LLC383,218$1.62M0.09%−4,321−1.1%Reduced
Geode Capital Management, LLC380,911$1.61M0.00%+6,245+1.7%Added
Federated Hermes, Inc.350,282$1.48M0.00%−5,086−1.4%Reduced
Marshall Wace, LLP321,257$1.36M0.00%+321,257New
Brandywine Global Investment Management, LLC318,601$1.35M0.01%00.0%Unchanged
Armistice Capital, LLC300,000$1.27M0.03%−700,000−70.0%Reduced
SEI Investments Co286,165$1.21M0.00%+914+0.3%Added
Two Sigma Investments, LP283,950$1.20M0.00%+200,343+239.6%Added
Two Sigma Advisers, LP275,400$1.16M0.00%+88,800+47.6%Added
EAM Investors, LLC272,787$1.15M0.24%+272,787New
Susquehanna International Group, LLP259,410$1.10M0.00%+115,485+80.2%Added
Dimensional Fund Advisors LP232,769$985.0K0.00%+175,464+306.2%Added
LSV Asset Management201,151$851.0K0.00%+19,052+10.5%Added
State Street Corp188,599$797.8K0.00%+6,896+3.8%Added
Connor, Clark & Lunn Investment Management Ltd.183,270$775.2K0.00%+33,976+22.8%Added
Assenagon Asset Management S.A.166,106$703.0K0.00%00.0%Unchanged
Citadel Advisors LLC150,557$636.9K0.00%−59,408−28.3%Reduced
D. E. Shaw & Co., Inc.132,184$559.1K0.00%−406,360−75.5%Reduced
Bridgeway Capital Management, LLC120,100$508.0K0.01%−6,000−4.8%Reduced
XTX Topco Ltd94,355$399.1K0.08%+66,299+236.3%Added
Prospera Financial Services Inc88,322$373.6K0.02%+6,075+7.4%Added
Goldman Sachs Group Inc76,451$323.4K0.00%−43,081−36.0%Reduced
Cubist Systematic Strategies, LLC75,438$319.1K0.00%+51,302+212.6%Added
Gsa Capital Partners LLP72,940$309.0K0.04%−67,381−48.0%Reduced
Northern Trust Corp66,436$281.0K0.00%−2,515−3.6%Reduced
FMR LLC63,909$270.3K0.00%−402−0.6%Reduced
Macquarie Group Ltd61,255$259.0K0.00%00.0%Unchanged
Bank of New York Mellon Corp58,003$245.4K0.00%+27,970+93.1%Added
Qube Research & Technologies Ltd56,628$239.5K0.00%+30,083+113.3%Added
Bailard, Inc.53,500$226.3K0.01%00.0%Unchanged
AlphaCentric Advisors LLC50,000$211.5K0.21%−365,000−88.0%Reduced
Virtu Financial LLC49,760$210.0K0.03%+49,760New
Walleye Capital LLC49,192$208.1K0.00%+30,909+169.1%Added
Man Group plc47,749$202.0K0.00%+27,568+136.6%Added
Jump Financial, LLC46,834$198.1K0.01%+46,834New
Jane Street Group, LLC40,818$172.7K0.00%+40,818New
683 Capital Management, LLC36,500$154.4K0.01%+36,500New
Bank of Montreal32,265$148.1K0.00%+32,265New
HRT Financial LP30,416$128.0K0.00%+30,416New
Patriot Financial Group Insurance Agency, LLC28,500$120.6K0.03%−22,000−43.6%Reduced
Crestline Management, LP28,496$120.5K0.02%+291+1.0%Added
Bank of America Corp26,496$112.1K0.00%−34,181−56.3%Reduced
Citigroup Inc26,473$112.0K0.00%+25,925+4,730.8%Added
Acrisure Capital Management, LLC25,409$107.5K0.12%+25,409New
Franklin Resources Inc24,234$102.5K0.00%00.0%Unchanged
Occudo Quantitative Strategies LP22,279$94.2K0.01%+22,279New
Boothbay Fund Management, LLC20,218$85.5K0.00%+20,218New
Charles Schwab Investment Management Inc19,453$82.3K0.00%+19,453New
Ergoteles LLC19,300$81.6K0.00%−103,309−84.3%Reduced
Buckingham Strategic Partners19,220$81.3K0.01%00.0%Unchanged
PDT Partners, LLC19,146$81.0K0.01%+19,146New
Squarepoint Ops LLC17,893$75.7K0.00%+17,893New
Advisor Group Holdings, Inc.17,430$74.0K0.00%−52−0.3%Reduced
Barclays PLC17,298$73.2K0.00%−36,812−68.0%Reduced
Tower Research Capital LLC (TRC)14,750$63.0K0.00%−4,610−23.8%Reduced
Bayesian Capital Management, LP11,901$50.3K0.01%+11,901New
Commonwealth Equity Services, LLC10,859$45.0K0.00%+10,859New
Prudential Financial Inc10,600$44.8K0.00%+10,600New
Running Point Capital Advisors, LLC10,000$42.3K0.03%00.0%Unchanged
UBS Group AG3,440$14.6K0.00%+15+0.4%Added
Lindbrook Capital, LLC2,793$11.8K0.00%00.0%Unchanged
Freedom Wealth Alliance, LLC1,721$7.28K0.01%+1,721New
Dark Forest Capital Management LP1,675$7.08K0.00%+1,675New
JPMorgan Chase & Co1,103$5.00K0.00%−1,746−61.3%Reduced
GHP Investment Advisors, Inc.1,170$4.95K0.00%00.0%Unchanged
Money Concepts Capital Corp1,000$4.23K0.00%00.0%Unchanged
Geneos Wealth Management Inc.1,000$4.23K0.00%00.0%Unchanged
Aspire Private Capital, LLC700$2.96K0.00%00.0%Unchanged
Crewe Advisors LLC579$2.45K0.00%00.0%Unchanged
Wells Fargo & Company267$1.13K0.00%+7+2.7%Added
BNP Paribas Arbitrage, SA242$1.02K0.00%−19,676−98.8%Reduced
US Bancorp200$8460.00%00.0%Unchanged
The PNC Financial Services Group, Inc.123$5200.00%00.0%Unchanged
Key Financial Inc50$1190.00%00.0%Unchanged
Cutler Group LP200$00.00%00.0%Unchanged
Rockefeller Capital Management L.P.14$00.00%−261−94.9%Reduced
Royal Bank of Canada100$00.00%+100New
Russell Investments Group, Ltd.0$00.00%−99,139−100.0%Sold out
Ally Bridge Group (NY) LLC0$00.00%−64,295−100.0%Sold out
Price T Rowe Associates Inc0$00.00%−45,400−100.0%Sold out
Atria Wealth Solutions, Inc.0$00.00%−25,200−100.0%Sold out
Diversified Trust Co0$00.00%−20,175−100.0%Sold out
HSBC Holdings PLC0$00.00%−18,913−100.0%Sold out
Simplex Trading, LLC0$00.00%−15,946−100.0%Sold out
Cambridge Investment Research Advisors, Inc.0$00.00%−14,945−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−13,851−100.0%Sold out
LMR Partners LLP0$00.00%−11,514−100.0%Sold out
Leonteq Securities AG0$00.00%−6,000−100.0%Sold out