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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Puma Biotechnology, Inc. as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
102
−14 vs. Q3 2021
Shares held
30.6M
−1.56M (−4.9%) vs. Q3 2021
Total value
$93.1M
−$132.9M (−58.8%) vs. Q3 2021
New holders
20
38 more added
Sold out
34
34 more reduced

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 102 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ4 2021: $93.1M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q3 2021.

Institutions holding PBYI in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Zurcher Kantonalbank (Zurich Cantonalbank)1$00.00%−1,863−99.9%Reduced
Rockefeller Capital Management L.P.275$00.00%−1,048−79.2%Reduced
Daiwa Securities Group Inc.87$00.00%00.0%Unchanged
Cutler Group LP200$00.00%00.0%Unchanged
KRS Capital Management, LLC58$00.00%+58New
US Bancorp200$1.00K0.00%00.0%Unchanged
Aspire Private Capital, LLC700$2.00K0.00%+200+40.0%Added
Quadrant Capital Group LLC586$2.00K0.00%+586New
Geneos Wealth Management Inc.1,000$3.00K0.00%00.0%Unchanged
TCI Wealth Advisors, Inc.1,429$4.00K0.00%+1,429New
Captrust Financial Advisors1,500$5.00K0.00%−114−7.1%Reduced
Lindbrook Capital, LLC2,793$8.00K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.2,522$8.00K0.00%00.0%Unchanged
Legal & General Group Plc3,554$11.0K0.00%−8,458−70.4%Reduced
Group One Trading, L.P.4,789$15.0K0.00%+4,314+908.2%Added
Royal Bank of Canada8,705$26.0K0.00%+1,454+20.1%Added
Tower Research Capital LLC (TRC)8,589$26.0K0.00%+4,039+88.8%Added
Citigroup Inc9,225$28.0K0.00%+3,114+51.0%Added
BNP Paribas Arbitrage, SA11,354$34.5K0.00%+4,447+64.4%Added
Invesco Ltd.11,820$36.0K0.00%−3,550−23.1%Reduced
Wolverine Trading, LLC11,847$38.0K0.00%+11,847New
ProShare Advisors LLC12,807$39.0K0.00%−37−0.3%Reduced
Quantbot Technologies LP14,469$43.0K0.00%+14,469New
Price T Rowe Associates Inc14,368$44.0K0.00%−300−2.0%Reduced
Advisor Group Holdings, Inc.15,571$49.0K0.00%−13,648−46.7%Reduced
Manteio Capital LLC16,409$50.0K0.06%+16,409New
Pinnacle Wealth Planning Services, Inc.16,749$51.0K0.01%+16,749New
California State Teachers Retirement System17,218$52.0K0.00%−25,232−59.4%Reduced
American International Group, Inc.17,154$52.0K0.00%−514−2.9%Reduced
UBS Group AG17,462$53.0K0.00%+10,938+167.7%Added
Deutsche Bank AG20,554$63.0K0.00%−58−0.3%Reduced
State Board of Administration of Florida Retirement System21,925$67.0K0.00%00.0%Unchanged
HSBC Holdings PLC23,284$71.0K0.00%00.0%Unchanged
Zebra Capital Management LLC25,058$76.0K0.12%−9,237−26.9%Reduced
Diversified Trust Co25,688$78.0K0.00%+6,053+30.8%Added
Algert Global LLC27,458$83.0K0.01%+8,870+47.7%Added
New York State Common Retirement Fund28,399$86.0K0.00%+9,358+49.1%Added
XTX Topco Ltd30,308$92.0K0.05%+30,308New
Prospera Financial Services Inc36,032$110.0K0.00%+672+1.9%Added
Squarepoint Ops LLC38,201$116.0K0.00%−61,156−61.6%Reduced
Rhumbline Advisers38,771$118.0K0.00%−838−2.1%Reduced
State of Wyoming41,521$126.0K0.06%+37,818+1,021.3%Added
Cubist Systematic Strategies, LLC44,867$136.0K0.00%+13,043+41.0%Added
Jump Financial, LLC45,400$138.0K0.01%+45,400New
Ikarian Capital, LLC49,843$152.0K0.04%00.0%Unchanged
Principal Financial Group Inc50,445$153.0K0.00%+5,883+13.2%Added
Two Sigma Advisers, LP53,000$161.0K0.00%−161,200−75.3%Reduced
Bank of America Corp53,392$162.0K0.00%−240,485−81.8%Reduced
Alliancebernstein L.P.55,800$170.0K0.00%−5,900−9.6%Reduced
Man Group plc55,901$170.0K0.00%+33,701+151.8%Added
Patriot Financial Group Insurance Agency, LLC59,500$181.0K0.03%+59,500New
Macquarie Group Ltd61,255$186.0K0.00%−6,993−10.2%Reduced
PDT Partners, LLC68,091$207.0K0.02%+1,363+2.0%Added
DuPont Capital Management Corp71,012$216.0K0.01%+71,012New
Simplex Trading, LLC78,512$238.0K0.01%+75,870+2,871.7%Added
HRT Financial LP80,077$243.0K0.00%−20,034−20.0%Reduced
Charles Schwab Investment Management Inc80,652$246.0K0.00%00.0%Unchanged
Citadel Advisors LLC82,598$251.0K0.00%−117,310−58.7%Reduced
Nuveen Asset Management, LLC99,561$283.0K0.00%−9,708−8.9%Reduced
Russell Investments Group, Ltd.96,921$293.0K0.00%−265,750−73.3%Reduced
Connor, Clark & Lunn Investment Management Ltd.100,215$305.0K0.00%+100,215New
Walleye Trading LLC101,947$310.0K0.01%+101,947New
ExodusPoint Capital Management, LP103,955$316.0K0.00%−10,562−9.2%Reduced
Voya Investment Management LLC104,010$317.0K0.00%+67,473+184.7%Added
Nomura Holdings Inc105,103$322.0K0.00%+105,103New
Bank of New York Mellon Corp116,096$354.0K0.00%−3,585−3.0%Reduced
Los Angeles Capital Management LLC117,681$358.0K0.00%−25,260−17.7%Reduced
JPMorgan Chase & Co143,497$437.0K0.00%−5,443−3.7%Reduced
Barclays PLC173,374$526.0K0.00%+109,731+172.4%Added
Prudential Financial Inc178,436$543.0K0.00%−181,259−50.4%Reduced
Panagora Asset Management Inc198,072$602.0K0.00%+2,258+1.2%Added
Wells Fargo & Company215,768$656.0K0.00%−41,257−16.1%Reduced
STRS Ohio237,000$720.0K0.00%+130,400+122.3%Added
Bridgeway Capital Management, LLC240,713$732.0K0.01%+240,713New
Allspring Global Investments Holdings, LLC247,200$751.0K0.00%+247,200New
Morgan Stanley278,964$848.0K0.00%+49,709+21.7%Added
SEI Investments Co284,073$863.0K0.00%+12,150+4.5%Added
Northern Trust Corp305,164$927.0K0.00%−44,638−12.8%Reduced
Federated Hermes, Inc.307,117$934.0K0.00%+9,914+3.3%Added
Assenagon Asset Management S.A.379,139$1.15M0.00%+379,139New
Brandywine Global Investment Management, LLC380,000$1.16M0.01%+380,000New
Marshall Wace, LLP396,967$1.21M0.00%+373,691+1,605.5%Added
Parametric Portfolio Associates LLC397,483$1.21M0.00%+140,057+54.4%Added
AlphaCentric Advisors LLC400,000$1.22M0.35%+251,500+169.4%Added
Walleye Capital LLC403,119$1.23M0.04%+403,119New
Globeflex Capital L P413,381$1.26M0.26%−311−0.1%Reduced
Susquehanna International Group, LLP456,862$1.39M0.00%+406,405+805.4%Added
Rice Hall James & Associates, LLC491,282$1.49M0.05%−55,026−10.1%Reduced
State Street Corp578,090$1.76M0.00%−59,630−9.4%Reduced
Bank of Montreal557,538$1.82M0.00%+304,475+120.3%Added
Geode Capital Management, LLC637,292$1.94M0.00%+30,141+5.0%Added
Kynam Capital Management, LP683,619$2.08M1.11%+683,619New
D. E. Shaw & Co., Inc.735,962$2.24M0.00%+685,690+1,364.0%Added
Jacobs Levy Equity Management, Inc756,675$2.30M0.02%+313,594+70.8%Added
Eversept Partners, LP1,117,898$3.40M0.28%+719,958+180.9%Added
Millennium Management LLC1,707,554$5.19M0.01%+40,769+2.4%Added
Acadian Asset Management LLC1,746,281$5.30M0.02%+446,734+34.4%Added
Renaissance Technologies LLC1,820,858$5.54M0.01%+188,923+11.6%Added
Camber Capital Management LP2,050,000$6.23M0.24%−1,375,000−40.1%Reduced
Goldman Sachs Group Inc2,283,165$6.94M0.00%+1,475,239+182.6%Added