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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

13F holders, Q4 2023

Institutional positions in Structure Therapeutics Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
122
+38 vs. Q3 2023
Shares held
42.7M
+9.88M (+30.1%) vs. Q3 2023
Total value
$1.74B
+$96.7M (+5.9%) vs. Q3 2023
New holders
55
37 more added
Sold out
17
24 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 122 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 38 institutionsQ2 2023: 48 institutionsQ3 2023: 84 institutionsQ4 2023: 122 institutionsQ1 2024: 119 institutionsQ2 2024: 167 institutionsQ3 2024: 161 institutionsQ4 2024: 165 institutionsQ1 2025: 151 institutionsQ2 2025: 173 institutionsQ3 2025: 158 institutionsQ4 2025: 199 institutionsQ1 2026: 198 institutionsQ2 2026: 191 institutions
Value heldQ4 2023: $1.74B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $346.2MQ2 2023: $699.4MQ3 2023: $1.64BQ4 2023: $1.74BQ1 2024: $1.86BQ2 2024: $2.33BQ3 2024: $2.69BQ4 2024: $1.65BQ1 2025: $990.0MQ2 2025: $1.14BQ3 2025: $1.59BQ4 2025: $4.58BQ1 2026: $3.23BQ2 2026: $3.62B
Institutions holding GPCR and their total value by quarter
QuarterHoldersValue
Q2 2026191$3.62B
Q1 2026198$3.23B
Q4 2025199$4.58B
Q3 2025158$1.59B
Q2 2025173$1.14B
Q1 2025151$990.0M
Q4 2024165$1.65B
Q3 2024161$2.69B
Q2 2024167$2.33B
Q1 2024119$1.86B
Q4 2023122$1.74B
Q3 202384$1.64B
Q2 202348$699.4M
Q1 202338$346.2M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q3 2023.

Institutions holding GPCR in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
GAMMA Investing LLC9$3930.00%+9New
Able Wealth Management LLC14$5710.00%+14New
Private Trust Co NA21$8560.00%+21New
Washington Trust Advisors, Inc.41$1.67K0.00%+41New
The PNC Financial Services Group, Inc.50$2.04K0.00%+50New
Clearstead Advisors, LLC59$2.40K0.00%+24+68.6%Added
Fairfield Financial Advisors, LTD59$2.40K0.00%+59New
Signaturefd, LLC100$4.08K0.00%00.0%Unchanged
Planning Capital Management Corp140$5.71K0.00%+140New
Daiwa Securities Group Inc.153$6.00K0.00%+153New
Rhumbline Advisers450$18.3K0.00%+450New
Steward Partners Investment Advisory, LLC679$27.7K0.00%+679New
Wells Fargo & Company726$29.6K0.00%+726New
Barclays PLC832$33.9K0.00%−5,000−85.7%Reduced
North Star Investment Management Corp.880$35.9K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)1,063$43.3K0.00%+142+15.4%Added
Advisor Group Holdings, Inc.1,211$49.3K0.00%+655+117.8%Added
Virtus ETF Advisers LLC1,580$64.4K0.04%−1,614−50.5%Reduced
Picton Mahoney Asset Management2,410$98.0K0.00%+90+3.9%Added
Sectoral Asset Management Inc3,400$138.6K0.06%+3,400New
ADAR1 Capital Management, LLC4,000$163.0K0.07%+4,000New
China Universal Asset Management Co., Ltd.4,349$177.3K0.03%+2,939+208.4%Added
Bleichroeder LP5,000$203.8K0.05%+5,000New
Cutler Group LP5,100$207.0K0.03%+5,100New
Raymond James & Associates5,705$232.5K0.00%+5,705New
Bayesian Capital Management, LP6,086$248.1K0.03%+6,086New
Royal Bank of Canada6,537$267.0K0.00%+6,434+6,246.6%Added
New York State Common Retirement Fund6,800$277.2K0.00%+6,800New
EntryPoint Capital, LLC7,835$319.4K0.31%+7,835New
JPMorgan Chase & Co7,846$319.8K0.00%−31,713−80.2%Reduced
Schonfeld Strategic Advisors LLC9,200$375.0K0.00%−15,400−62.6%Reduced
FIL Ltd9,304$379.2K0.00%+695+8.1%Added
Temasek Holdings (Private) Ltd9,617$392.0K0.00%00.0%Unchanged
Voya Investment Management LLC9,730$396.6K0.00%−76,744−88.7%Reduced
Teachers Retirement System of the State of Kentucky11,656$475.0K0.00%+11,656New
Susquehanna International Group, LLP11,702$477.0K0.00%+11,702New
Brandywine Managers, LLC12,007$489.4K0.54%+1,007+9.2%Added
Bellevue Group AG12,300$501.3K0.01%−4,500−26.8%Reduced
Simplex Trading, LLC12,322$502.0K0.02%+12,322New
First Trust Advisors LP12,967$528.5K0.00%+12,967New
Prelude Capital Management, LLC13,700$558.4K0.05%+500+3.8%Added
Walleye Trading LLC13,879$565.7K0.01%+13,879New
State Street Corp13,936$568.0K0.00%−524−3.6%Reduced
Ikarian Capital, LLC14,524$592.0K0.16%−123,300−89.5%Reduced
M&T Bank Corp14,600$595.5K0.00%+14,600New
Natixis Advisors, L.P.15,558$634.0K0.00%+15,558New
Ensign Peak Advisors, Inc16,300$664.4K0.00%00.0%Unchanged
Citigroup Inc16,680$679.9K0.00%+16,555+13,244.0%Added
Millennium Management LLC16,769$683.5K0.00%−283,105−94.4%Reduced
EFG Asset Management (North America) Corp.17,390$704.6K0.13%+17,390New
Group One Trading, L.P.17,914$730.2K0.02%+17,914New
Geode Capital Management, LLC22,194$904.6K0.00%+14,403+184.9%Added
Twinbeech Capital LP24,290$990.1K0.02%+24,290New
Kennedy Capital Management, Inc.25,876$1.05M0.02%+25,876New
TrueMark Investments, LLC26,322$1.07M1.07%+26,322New
Russell Investments Group, Ltd.28,393$1.16M0.00%+28,393New
E Fund Management Co., Ltd.28,589$1.17M0.07%+28,589New
Engineers Gate Manager LP29,414$1.20M0.03%+29,414New
AlphaCentric Advisors LLC30,000$1.22M0.82%+30,000New
Wexford Capital LP32,462$1.32M0.28%−35,516−52.2%Reduced
Pier Capital, LLC35,653$1.45M0.21%+35,653New
Parkman Healthcare Partners LLC38,678$1.58M0.22%+8,678+28.9%Added
Jane Street Group, LLC38,798$1.58M0.00%+38,798New
Qube Research & Technologies Ltd40,676$1.66M0.00%+40,676New
Allspring Global Investments Holdings, LLC48,085$1.96M0.00%+48,085New
Weiss Multi-Strategy Advisers LLC48,914$1.99M0.05%+22,977+88.6%Added
Manufacturers Life Insurance Company, The53,204$2.17M0.00%−1,882−3.4%Reduced
UBS Group AG59,637$2.43M0.00%+59,637New
Ameriprise Financial Inc62,757$2.56M0.00%+62,757New
Exome Asset Management LLC68,100$2.78M2.74%+68,100New
HighVista Strategies LLC74,832$3.05M1.11%00.0%Unchanged
Bank of America Corp76,504$3.12M0.00%+66,630+674.8%Added
Platinum Investment Management Ltd77,093$3.14M0.13%+24,632+47.0%Added
GMT Capital Corp81,700$3.33M0.13%−31,500−27.8%Reduced
Artal Group S.A.86,600$3.53M0.12%+86,600New
Schroder Investment Management Group91,145$3.72M0.00%+91,145New
Marshall Wace, LLP105,770$4.31M0.01%−1,748−1.6%Reduced
Bamco Inc118,333$4.82M0.01%+118,333New
Victory Capital Management Inc125,447$5.11M0.01%−25,511−16.9%Reduced
Pictet Asset Management Holding SA138,797$5.66M0.01%+138,797New
Ghost Tree Capital, LLC150,000$6.11M3.52%+95,000+172.7%Added
TD Asset Management Inc157,258$6.41M0.01%+5,082+3.3%Added
Sofinnova Investments, Inc.174,838$7.13M0.40%−27,281−13.5%Reduced
Alyeska Investment Group, L.P.178,677$7.28M0.05%+178,677New
Woodline Partners LP179,219$7.30M0.08%+9,219+5.4%Added
Monashee Investment Management LLC191,855$7.82M1.38%−441,911−69.7%Reduced
Invesco Ltd.195,627$7.97M0.00%+82,534+73.0%Added
Candriam Luxembourg S.C.A.210,000$8.56M0.06%+210,000New
MPM Oncology Impact Management LP230,696$9.40M2.20%−650.0%Reduced
ArrowMark Colorado Holdings LLC278,732$11.4M0.13%+228,732+457.5%Added
Braidwell LP280,158$11.4M0.42%+280,158New
Rock Springs Capital Management LP286,676$11.7M0.29%+286,676New
Morgan Stanley287,069$11.7M0.00%+263,255+1,105.5%Added
Fred Alger Management, LLC291,097$11.9M0.06%+191,757+193.0%Added
Deep Track Capital, LP300,000$12.2M0.43%−1,615,000−84.3%Reduced
Frazier Life Sciences Management, L.P.317,190$12.9M0.69%+317,190New
Boxer Capital, LLC400,000$16.3M0.81%+400,000New
Octagon Capital Advisors LP414,000$16.9M2.70%+414,000New
Goldman Sachs Group Inc427,735$17.4M0.00%+356,302+498.8%Added
Ra Capital Management, L.P.486,832$19.8M0.31%+486,832New