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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 5 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Edgewise Therapeutics, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
214
+20 vs. Q4 2025
Shares held
118.5M
+2.37M (+2.0%) vs. Q4 2025
Total value
$3.72B
+$839.3M (+29.1%) vs. Q4 2025
New holders
44
65 more added
Sold out
24
66 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 214 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ1 2026: $3.72B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q4 2025.

Institutions holding EWTX in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
LMR Partners LLP20,000$630.0K0.01%00.0%Unchanged
BNP Paribas Arbitrage, SA23,911$753.2K0.00%+6,850+40.2%Added
Wells Fargo & Company25,244$795.2K0.00%−50,198−66.5%Reduced
China Universal Asset Management Co., Ltd.25,436$801.2K0.06%+8,185+47.4%Added
Susquehanna International Group, LLP26,674$840.2K0.00%−43,522−62.0%Reduced
Wellington Management Group LLP27,409$863.4K0.00%−83,978−75.4%Reduced
Vanguard Global Advisers, LLC29,326$923.8K0.00%+29,326New
Tudor Investment Corp Et Al29,889$941.5K0.01%+29,889New
Handelsbanken Fonder AB31,100$980.0K0.00%00.0%Unchanged
Creative Planning31,268$984.9K0.00%+6,800+27.8%Added
Mirae Asset Global ETFs Holdings Ltd.31,614$995.8K0.00%+245+0.8%Added
Algert Global LLC32,520$1.02M0.02%+32,520New
State of Wisconsin Investment Board32,896$1.04M0.00%−7,101−17.8%Reduced
Manufacturers Life Insurance Company, The35,450$1.12M0.00%−1,309−3.6%Reduced
Jane Street Group, LLC35,578$1.12M0.00%+35,578New
Vanguard Asset Management, Ltd35,744$1.13M0.00%+35,744New
Longaeva Partners L.P.36,931$1.16M0.06%+36,931New
MetLife Investment Management38,084$1.20M0.01%−207−0.5%Reduced
Knights of Columbus Asset Advisors LLC38,414$1.21M0.07%−262−0.7%Reduced
Caption Management, LLC38,675$1.22M0.06%+38,675New
Voya Investment Management LLC39,153$1.23M0.00%−495−1.2%Reduced
Franklin Resources Inc41,726$1.31M0.00%−1,419−3.3%Reduced
Legal & General Group Plc42,537$1.34M0.00%−10,210−19.4%Reduced
Silverarc Capital Management, LLC42,615$1.34M0.16%+563+1.3%Added
Jain Global LLC46,401$1.46M0.02%−67,455−59.2%Reduced
SEI Investments Co49,082$1.55M0.00%+17,832+57.1%Added
Ishara Investments LP49,200$1.55M1.57%−8,800−15.2%Reduced
Two Sigma Investments, LP50,848$1.60M0.00%00.0%Unchanged
HighMark Wealth Management LLC53,179$1.68M0.68%00.0%Unchanged
Federated Hermes, Inc.56,778$1.79M0.00%−25,318−30.8%Reduced
J. Goldman & Co LP61,421$1.93M0.09%+61,421New
Artia Global Partners LP65,500$2.06M0.47%+65,500New
Nomura Asset Management International Inc.67,408$2.12M0.00%+67,408New
Price T Rowe Associates Inc69,427$2.19M0.00%+12,112+21.1%Added
California State Teachers Retirement System73,419$2.31M0.00%+23,027+45.7%Added
DekaBank Deutsche Girozentrale80,000$2.57M0.00%00.0%Unchanged
Rhumbline Advisers83,540$2.63M0.00%−1,535−1.8%Reduced
Alps Advisors Inc87,326$2.75M0.01%+397+0.5%Added
New York State Common Retirement Fund88,937$2.80M0.00%00.0%Unchanged
ADAR1 Capital Management, LLC90,599$2.85M0.17%−400−0.4%Reduced
HighVista Strategies LLC91,931$2.90M0.80%−79,206−46.3%Reduced
Schonfeld Strategic Advisors LLC99,075$3.12M0.03%+39,749+67.0%Added
Swiss National Bank103,900$3.27M0.00%00.0%Unchanged
D. E. Shaw & Co., Inc.104,863$3.30M0.00%−289,832−73.4%Reduced
DAFNA Capital Management LLC112,236$3.54M0.80%−47,500−29.7%Reduced
Moody Aldrich Partners LLC114,141$3.60M0.65%+71,007+164.6%Added
UBS Asset Management Americas Inc114,720$3.61M0.00%+16,657+17.0%Added
Quantum Private Wealth, LLC116,624$3.67M1.13%+10,600+10.0%Added
KVP Capital Advisors, LP133,000$4.19M3.13%00.0%Unchanged
Invesco Ltd.138,399$4.36M0.00%+62,961+83.5%Added
Schroder Investment Management Group145,286$4.40M0.00%00.0%Unchanged
JPMorgan Chase & Co147,573$4.47M0.00%+1,535+1.1%Added
Freestone Grove Partners LP148,426$4.68M0.03%+148,426New
Eventide Asset Management, LLC149,863$4.72M0.08%−418,447−73.6%Reduced
Ally Bridge Group (NY) LLC161,000$5.07M5.04%−34,000−17.4%Reduced
Neuberger Berman Group LLC168,678$5.31M0.00%+41,542+32.7%Added
Barclays PLC177,244$5.58M0.00%−195,494−52.4%Reduced
Bank of New York Mellon Corp192,434$6.06M0.00%−6,180−3.1%Reduced
Ameriprise Financial Inc200,661$6.32M0.00%−1,636−0.8%Reduced
Granahan Investment Management Inc200,843$6.33M0.31%−31,452−13.5%Reduced
SEB Asset Management AB206,512$6.51M0.03%+206,512New
Peregrine Capital Management LLC208,672$6.57M0.24%+208,672New
Deutsche Bank AG221,868$6.99M0.00%+7,099+3.3%Added
Woodline Partners LP224,290$7.07M0.03%+980.0%Added
Kennedy Capital Management, Inc.264,204$8.32M0.18%+22,695+9.4%Added
Sio Capital Management, LLC268,986$8.47M1.22%+31,505+13.3%Added
Universal- Beteiligungs- und Servicegesellschaft mbH283,312$8.92M0.02%+11,927+4.4%Added
StemPoint Capital LP290,864$9.16M1.76%−70,012−19.4%Reduced
Parkman Healthcare Partners LLC322,828$10.2M1.05%−104,862−24.5%Reduced
Nuveen, LLC335,783$10.6M0.00%+166,317+98.1%Added
Millennium Management LLC342,867$10.8M0.01%+216,431+171.2%Added
Squadron Capital Management LLC350,000$11.0M4.41%00.0%Unchanged
Sofinnova Investments, Inc.386,498$12.2M0.61%−51,321−11.7%Reduced
Healthcare of Ontario Pension Plan Trust Fund404,200$12.7M0.02%−236,200−36.9%Reduced
Citadel Advisors LLC429,032$13.5M0.01%+305,935+248.5%Added
Candriam Luxembourg S.C.A.447,416$14.1M0.07%−53,798−10.7%Reduced
Opaleye Management Inc.500,000$15.8M2.07%00.0%Unchanged
Vanguard Fiduciary Trust Co521,726$16.4M0.00%+521,726New
Vanguard Portfolio Management LLC557,260$17.6M0.00%+557,260New
Northern Trust Corp576,556$18.2M0.00%+16,907+3.0%Added
Charles Schwab Investment Management Inc596,310$18.8M0.00%−15,074−2.5%Reduced
Goldman Sachs Group Inc629,820$19.8M0.00%−88,552−12.3%Reduced
Marshall Wace, LLP648,393$20.4M0.02%−33,528−4.9%Reduced
Artisan Partners Limited Partnership659,067$20.8M0.03%−45,010−6.4%Reduced
Victory Capital Management Inc789,043$24.9M0.02%+42,481+5.7%Added
Qube Research & Technologies Ltd825,910$26.0M0.04%+529,702+178.8%Added
Standard Life Aberdeen plc826,059$26.0M0.04%+4,119+0.5%Added
First Light Asset Management, LLC1,001,846$31.6M2.83%−571,855−36.3%Reduced
FMR LLC1,017,052$32.0M0.00%+324,097+46.8%Added
American Century Companies Inc1,147,176$36.1M0.02%−39,291−3.3%Reduced
Dimensional Fund Advisors LP1,219,717$38.4M0.01%+6,060+0.5%Added
UBS Group AG1,311,125$41.3M0.01%−805,948−38.1%Reduced
Bank of America Corp1,327,360$41.8M0.00%−147,437−10.0%Reduced
Alliancebernstein L.P.1,722,169$42.7M0.01%+685,999+66.2%Added
Soleus Capital Management, L.P.1,449,915$45.7M1.85%+539,915+59.3%Added
Bellevue Group AG1,528,518$48.1M1.15%00.0%Unchanged
Integral Health Asset Management, LLC1,600,000$50.4M2.67%+100,000+6.7%Added
MPM Oncology Impact Management LP1,660,696$52.3M4.04%+5,440+0.3%Added
State Street Corp1,716,823$54.1M0.00%−5200.0%Reduced
Geode Capital Management, LLC1,789,819$56.4M0.00%+43,597+2.5%Added