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Edgewise Therapeutics, Inc.

EWTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001710072

In the last 90 days, Edgewise Therapeutics, Inc. insiders filed 0 open-market purchases and 5 sales; 226 institutions reported holding it in 13F filings for Q2 2026, worth $4.82B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Edgewise Therapeutics, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
201
+25 vs. Q3 2024
Shares held
99.0M
−2.18M (−2.2%) vs. Q3 2024
Total value
$2.64B
−$58.2M (−2.2%) vs. Q3 2024
New holders
45
71 more added
Sold out
20
63 more reduced

1 institution that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting EWTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 201 institutions
Q1 2021: 31 institutionsQ2 2021: 46 institutionsQ3 2021: 48 institutionsQ4 2021: 58 institutionsQ1 2022: 72 institutionsQ2 2022: 78 institutionsQ3 2022: 94 institutionsQ4 2022: 90 institutionsQ1 2023: 85 institutionsQ2 2023: 95 institutionsQ3 2023: 85 institutionsQ4 2023: 116 institutionsQ1 2024: 129 institutionsQ2 2024: 140 institutionsQ3 2024: 177 institutionsQ4 2024: 201 institutionsQ1 2025: 193 institutionsQ2 2025: 179 institutionsQ3 2025: 173 institutionsQ4 2025: 199 institutionsQ1 2026: 214 institutionsQ2 2026: 226 institutions
Value heldQ4 2024: $2.64B
Q1 2021: $1.48BQ2 2021: $1.03BQ3 2021: $795.8MQ4 2021: $769.4MQ1 2022: $523.5MQ2 2022: $405.7MQ3 2022: $633.5MQ4 2022: $594.1MQ1 2023: $443.1MQ2 2023: $538.8MQ3 2023: $392.2MQ4 2023: $871.4MQ1 2024: $1.67BQ2 2024: $1.83BQ3 2024: $2.71BQ4 2024: $2.64BQ1 2025: $2.32BQ2 2025: $1.56BQ3 2025: $1.82BQ4 2025: $3.02BQ1 2026: $3.72BQ2 2026: $4.82B
Institutions holding EWTX and their total value by quarter
QuarterHoldersValue
Q2 2026226$4.82B
Q1 2026214$3.72B
Q4 2025199$3.02B
Q3 2025173$1.82B
Q2 2025179$1.56B
Q1 2025193$2.32B
Q4 2024201$2.64B
Q3 2024177$2.71B
Q2 2024140$1.83B
Q1 2024129$1.67B
Q4 2023116$871.4M
Q3 202385$392.2M
Q2 202395$538.8M
Q1 202385$443.1M
Q4 202290$594.1M
Q3 202294$633.5M
Q2 202278$405.7M
Q1 202272$523.5M
Q4 202158$769.4M
Q3 202148$795.8M
Q2 202146$1.03B
Q1 202131$1.48B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Edgewise Therapeutics, Inc.; share changes are against Q3 2024.

Institutions holding EWTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
OrbiMed Advisors LLC15,021,721$401.1M8.33%00.0%Unchanged
TCG Crossover Management, LLC0$00.00%−2,112,984−100.0%Sold out
EcoR1 Capital, LLC0$00.00%−1,250,385−100.0%Sold out
VR Adviser, LLC0$00.00%−1,000,000−100.0%Sold out
Monashee Investment Management LLC0$00.00%−75,000−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−45,400−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−39,937−100.0%Sold out
SG Americas Securities, LLC0$00.00%−29,629−100.0%Sold out
XTX Topco Ltd0$00.00%−28,303−100.0%Sold out
Renaissance Technologies LLC0$00.00%−27,465−100.0%Sold out
NEOS Investment Management LLC0$00.00%−23,359−100.0%Sold out
Fred Alger Management, LLC0$00.00%−21,128−100.0%Sold out
PDT Partners, LLC0$00.00%−20,551−100.0%Sold out
UBS Oconnor LLC0$00.00%−20,000−100.0%Sold out
ADAR1 Capital Management, LLC0$00.00%−18,178−100.0%Sold out
Nomura Holdings Inc0$00.00%−13,335−100.0%Sold out
Cowen and Company, LLC0$00.00%−11,000−100.0%Sold out
Chicago Partners Investment Group LLC0$00.00%−6,018−100.0%Sold out
Pale Fire Capital SE0$00.00%−7,686−100.0%Sold out
Catalyst Funds Management Pty Ltd0$00.00%−1,200−100.0%Sold out
Capital Performance Advisors LLP0$00.00%−20−100.0%Sold out
Ghost Tree Capital, LLC––––Not filed