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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q4 2024

Institutional positions in 89bio, Inc. as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
156
+14 vs. Q3 2024
Shares held
121.3M
+17.2M (+16.5%) vs. Q3 2024
Total value
$948.7M
+$177.8M (+23.1%) vs. Q3 2024
New holders
33
73 more added
Sold out
19
35 more reduced

2 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 156 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2024: $948.7M
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q3 2024.

Institutions holding ETNB in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Algert Global LLC185,407$1.45M0.03%+123,190+198.0%Added
Exome Asset Management LLC225,323$1.76M1.33%−75,277−25.0%Reduced
Two Sigma Investments, LP237,521$1.86M0.00%−131,167−35.6%Reduced
Newtyn Management, LLC240,000$1.88M0.33%00.0%Unchanged
Assenagon Asset Management S.A.242,602$1.90M0.00%+242,602New
Bank of New York Mellon Corp248,156$1.94M0.00%+9,314+3.9%Added
Harbor Capital Advisors, Inc.251,898$1.97M0.09%+23,968+10.5%Added
Comerica Bank256,583$2.01M0.01%+30,603+13.5%Added
Caption Management, LLC266,362$2.08M0.09%+11,162+4.4%Added
Nuveen Asset Management, LLC286,492$2.24M0.00%−3,420−1.2%Reduced
Renaissance Technologies LLC297,700$2.33M0.00%−14,324−4.6%Reduced
JPMorgan Chase & Co308,459$2.41M0.00%+208,992+210.1%Added
Ally Bridge Group (NY) LLC317,833$2.49M2.13%+317,833New
Standard Life Aberdeen plc329,338$2.58M0.00%−141,049−30.0%Reduced
Wellington Management Group LLP334,805$2.62M0.00%+15,760+4.9%Added
Morgan Stanley341,951$2.67M0.00%−58,287−14.6%Reduced
Dimensional Fund Advisors LP342,229$2.68M0.00%+342,229New
Adage Capital Partners GP, L.L.C.350,000$2.74M0.00%−525,000−60.0%Reduced
BNP Paribas Arbitrage, SA351,331$2.75M0.00%+351,331New
Bank of America Corp358,574$2.80M0.00%+32,867+10.1%Added
Raymond James Financial Inc377,370$2.95M0.00%+377,370New
Woodline Partners LP394,826$3.09M0.02%+341,479+640.1%Added
Walleye Capital LLC432,846$3.38M0.03%−2,452−0.6%Reduced
ADAR1 Capital Management, LLC515,138$4.03M0.83%+508,578+7,752.7%Added
StemPoint Capital LP545,800$4.27M1.07%+545,800New
Rock Springs Capital Management LP552,741$4.32M0.16%+552,741New
Sphera Funds Management Ltd.556,532$4.35M0.80%+19,985+3.7%Added
Barclays PLC639,974$5.00M0.00%+425,206+198.0%Added
Millennium Management LLC708,196$5.54M0.00%+326,215+85.4%Added
Erste Asset Management GmbH763,000$5.95M0.07%00.0%Unchanged
Laurion Capital Management LP780,273$6.10M0.38%−30,260−3.7%Reduced
Goldman Sachs Group Inc807,082$6.31M0.00%+73,585+10.0%Added
Charles Schwab Investment Management Inc810,826$6.34M0.00%+89,776+12.5%Added
Northern Trust Corp854,787$6.68M0.00%+60,075+7.6%Added
University of Wisconsin Foundation917,357$7.17M5.21%+193,225+26.7%Added
Alyeska Investment Group, L.P.925,397$7.24M0.03%+116,833+14.4%Added
Frazier Life Sciences Management, L.P.1,000,000$7.82M0.32%00.0%Unchanged
Integral Health Asset Management, LLC1,000,000$7.82M0.69%+500,000+100.0%Added
Balyasny Asset Management LLC1,019,449$7.97M0.02%+1,019,449New
Alliancebernstein L.P.1,042,136$8.15M0.00%+455,074+77.5%Added
Candriam Luxembourg S.C.A.1,055,661$8.26M0.05%+207,582+24.5%Added
Redmile Group, LLC2,167,176$16.9M1.18%+597,326+38.0%Added
Geode Capital Management, LLC2,207,608$17.3M0.00%+132,638+6.4%Added
State Street Corp2,945,232$23.0M0.00%−306,455−9.4%Reduced
Pictet Asset Management Holding SA3,007,034$23.5M0.03%−239,574−7.4%Reduced
Westfield Capital Management Co LP3,886,794$30.4M0.13%+880,756+29.3%Added
Avoro Capital Advisors LLC4,100,000$32.1M0.45%+4,100,000New
BVF Inc4,333,885$33.9M1.15%−2,477,746−36.4%Reduced
Citadel Advisors LLC4,729,852$37.0M0.03%+2,173,125+85.0%Added
Vanguard Group Inc5,692,331$44.5M0.00%+686,054+13.7%Added
Deep Track Capital, LP6,478,249$50.7M1.90%+3,711,737+134.2%Added
RTW Investments, LP7,478,061$58.5M0.88%+99,513+1.3%Added
BlackRock, Inc.7,890,099$61.7M0.00%+340,797+4.5%Added
Suvretta Capital Management, LLC10,202,696$79.8M2.96%+2,211,052+27.7%Added
Ra Capital Management, L.P.14,175,398$110.9M1.48%00.0%Unchanged
Janus Henderson Group PLC16,514,056$129.2M0.07%+1,355,838+8.9%Added
ExodusPoint Capital Management, LP0$00.00%−871,404−100.0%Sold out
Franklin Resources Inc0$00.00%−504,563−100.0%Sold out
MPM Oncology Impact Management LP0$00.00%−330,000−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−130,894−100.0%Sold out
Nomura Holdings Inc0$00.00%−99,997−100.0%Sold out
Alps Advisors Inc0$00.00%−81,349−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−80,904−100.0%Sold out
HighVista Strategies LLC0$00.00%−66,787−100.0%Sold out
Trexquant Investment LP0$00.00%−54,389−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−46,617−100.0%Sold out
Quest Partners LLC0$00.00%−22,074−100.0%Sold out
Prudential Financial Inc0$00.00%−21,815−100.0%Sold out
Engineers Gate Manager LP0$00.00%−21,142−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−21,096−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−14,259−100.0%Sold out
Squarepoint Ops LLC0$00.00%−12,617−100.0%Sold out
Simplex Trading, LLC0$00.00%−7,925−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−177−100.0%Sold out
Bessemer Group Inc0$00.00%−130−100.0%Sold out
Raymond James & Associates––––Not filed
Raymond James Financial Services Advisors, Inc.––––Not filed