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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q4 2023

Institutional positions in 89bio, Inc. as of Dec 31, 2023. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
153
−7 vs. Q3 2023
Shares held
94.2M
+22.2M (+30.9%) vs. Q3 2023
Total value
$1.05B
−$59.2M (−5.3%) vs. Q3 2023
New holders
33
70 more added
Sold out
40
41 more reduced

Compare with Q3 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2023: 153 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ4 2023: $1.05B
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q4 2023

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q3 2023.

Institutions holding ETNB in Q4 2023
InstitutionSharesValue% of portfolioChange in sharesAction
Ra Capital Management, L.P.11,416,948$127.5M1.99%00.0%Unchanged
Janus Henderson Group PLC8,915,141$99.6M0.06%+4,885,938+121.3%Added
RTW Investments, LP5,578,931$62.3M0.97%+5,578,931New
BlackRock Inc.5,454,196$60.9M0.00%+487,956+9.8%Added
State Street Corp5,399,358$60.3M0.00%+1,092,718+25.4%Added
Suvretta Capital Management, LLC4,888,434$54.6M2.50%+2,194,030+81.4%Added
Pictet Asset Management Holding SA4,557,680$50.9M0.06%+669,726+17.2%Added
Vanguard Group Inc4,307,585$48.1M0.00%+781,803+22.2%Added
BVF Inc4,047,354$45.2M1.13%+2,201,200+119.2%Added
Holocene Advisors, LP3,490,628$39.0M0.15%+1,254,823+56.1%Added
Adage Capital Partners GP, L.L.C.3,125,000$34.9M0.07%+1,426,583+84.0%Added
Laurion Capital Management LP2,704,202$30.2M1.08%+1,498,564+124.3%Added
Citadel Advisors LLC2,178,339$24.3M0.02%+674,330+44.8%Added
Frazier Life Sciences Management, L.P.2,000,000$22.3M1.19%+2,000,000New
Redmile Group, LLC1,969,402$22.0M0.79%+1,207,447+158.5%Added
Federated Hermes, Inc.1,962,566$21.9M0.05%−167,035−7.8%Reduced
Westfield Capital Management Co LP1,761,148$19.7M0.11%+449,262+34.2%Added
Morgan Stanley1,489,260$16.6M0.00%+889,506+148.3%Added
Geode Capital Management, LLC1,377,710$15.4M0.00%+83,722+6.5%Added
Superstring Capital Management LP1,021,477$11.4M8.14%+1,021,477New
Franklin Resources Inc827,703$9.25M0.00%+3200.0%Added
Orchard Capital Managment, LLC739,208$8.26M2.59%+196,329+36.2%Added
Eagle Asset Management Inc702,095$7.84M0.04%−10,803−1.5%Reduced
Goldman Sachs Group Inc631,112$7.05M0.00%+112,438+21.7%Added
Northern Trust Corp618,001$6.90M0.00%+37,339+6.4%Added
Alyeska Investment Group, L.P.583,187$6.51M0.04%+123,300+26.8%Added
Millennium Management LLC558,885$6.24M0.01%+453,032+428.0%Added
Marshall Wace, LLP554,337$6.19M0.01%−616,419−52.7%Reduced
Barclays PLC543,552$6.07M0.00%−80,813−12.9%Reduced
Erste Asset Management GmbH503,000$5.64M0.08%+450,000+849.1%Added
Charles Schwab Investment Management Inc499,353$5.58M0.00%+10,349+2.1%Added
Rafferty Asset Management, LLC453,674$5.07M0.02%+71,729+18.8%Added
Sphera Funds Management Ltd.408,674$4.56M0.85%+89,373+28.0%Added
StemPoint Capital LP408,257$4.56M1.23%+408,257New
Qube Research & Technologies Ltd403,324$4.51M0.01%+403,324New
Deutsche Bank AG378,840$4.23M0.00%+346,276+1,063.4%Added
Alliancebernstein L.P.298,989$3.34M0.00%−44,685−13.0%Reduced
UBS Group AG284,497$3.18M0.00%+183,515+181.7%Added
Candriam Luxembourg S.C.A.280,000$3.13M0.02%+60,000+27.3%Added
Newtyn Management, LLC272,500$3.04M0.60%+72,000+35.9%Added
Bank of America Corp271,899$3.04M0.00%−163,502−37.6%Reduced
Caption Management, LLC260,000$2.90M0.32%+144,000+124.1%Added
Royal Bank of Canada248,931$2.78M0.00%+23,432+10.4%Added
Nuveen Asset Management, LLC242,389$2.71M0.00%−155,413−39.1%Reduced
Wellington Management Group LLP239,027$2.67M0.00%+239,027New
Weiss Multi-Strategy Advisers LLC230,000$2.57M0.07%+163,669+246.7%Added
Bank of New York Mellon Corp222,420$2.48M0.00%+4,515+2.1%Added
Parkman Healthcare Partners LLC219,448$2.45M0.35%−144,105−39.6%Reduced
Citigroup Inc214,602$2.40M0.00%+52,746+32.6%Added
Standard Life Aberdeen plc214,192$2.39M0.01%+214,192New
JPMorgan Chase & Co198,932$2.22M0.00%−52,373−20.8%Reduced
Two Sigma Advisers, LP167,300$1.87M0.00%−245,400−59.5%Reduced
Susquehanna International Group, LLP166,210$1.86M0.00%−214,857−56.4%Reduced
Silverarc Capital Management, LLC158,719$1.77M0.55%+98,472+163.4%Added
Comerica Bank155,930$1.74M0.01%+155,854+205,071.1%Added
Swiss National Bank142,800$1.60M0.00%+30,700+27.4%Added
Monashee Investment Management LLC140,000$1.56M0.28%+140,000New
Two Sigma Investments, LP128,758$1.44M0.00%−83,019−39.2%Reduced
University of Wisconsin Foundation126,516$1.41M2.35%00.0%Unchanged
State of Wisconsin Investment Board121,863$1.36M0.00%−4,109−3.3%Reduced
Raymond James & Associates108,403$1.21M0.00%+5,415+5.3%Added
Raymond James Financial Services Advisors, Inc.104,286$1.16M0.00%−27,819−21.1%Reduced
Invesco Ltd.101,218$1.13M0.00%+6,654+7.0%Added
DekaBank Deutsche Girozentrale90,000$1.02M0.00%+70,000+350.0%Added
Jane Street Group, LLC89,297$997.4K0.00%−84,653−48.7%Reduced
Twinbeech Capital LP86,689$968.3K0.02%−49,427−36.3%Reduced
Wells Fargo & Company85,855$959.0K0.00%−75,316−46.7%Reduced
Rhumbline Advisers84,089$939.3K0.00%+2,616+3.2%Added
Nomura Holdings Inc82,000$915.9K0.01%+82,000New
1492 Capital Management LLC79,218$884.9K0.50%+814+1.0%Added
UBS Oconnor LLC79,075$883.3K0.03%−19,763−20.0%Reduced
Schonfeld Strategic Advisors LLC77,758$868.6K0.01%−199,804−72.0%Reduced
California State Teachers Retirement System75,149$839.4K0.00%+16,370+27.9%Added
Legal & General Group Plc73,569$821.8K0.00%+22,943+45.3%Added
Profund Advisors LLC73,141$817.0K0.04%+9,116+14.2%Added
HRT Financial LP65,192$728.0K0.01%+65,192New
Jefferies Financial Group Inc.64,116$716.2K0.01%+26,066+68.5%Added
UBS Asset Management Americas Inc59,100$660.1K0.00%+6,411+12.2%Added
Credit Suisse AG56,835$634.8K0.00%+6,874+13.8%Added
Alps Advisors Inc52,456$585.9K0.00%−3,215−5.8%Reduced
Algert Global LLC46,824$523.0K0.02%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.45,644$509.8K0.00%+3,278+7.7%Added
Pennant Investors, LP44,500$497.1K0.15%+44,500New
Parkwood LLC44,206$494.0K0.08%+16,341+58.6%Added
Skandinaviska Enskilda Banken AB (publ)39,400$440.1K0.00%−12,000−23.3%Reduced
Dynamic Technology Lab Private Ltd38,545$431.0K0.05%+19,730+104.9%Added
Corton Capital Inc.35,479$396.3K0.13%+35,479New
Bourgeon Capital Management LLC35,300$394.3K0.09%−20,200−36.4%Reduced
ExodusPoint Capital Management, LP35,218$393.0K0.00%+35,218New
Entropy Technologies, LP33,507$374.3K0.07%+33,507New
Manufacturers Life Insurance Company, The33,391$373.0K0.00%−17,530−34.4%Reduced
MetLife Investment Management32,619$364.4K0.00%00.0%Unchanged
American International Group, Inc.31,828$355.5K0.00%+978+3.2%Added
Walleye Capital LLC30,193$337.3K0.00%−55,056−64.6%Reduced
Prudential Financial Inc28,896$322.8K0.00%+28,896New
SG Americas Securities, LLC28,319$316.0K0.00%+28,319New
New York State Common Retirement Fund26,041$290.9K0.00%+1,190+4.8%Added
Voya Investment Management LLC25,343$283.1K0.00%+478+1.9%Added
E Fund Management Co., Ltd.24,363$272.1K0.02%+4,742+24.2%Added
Price T Rowe Associates Inc24,221$271.0K0.00%−358,024−93.7%Reduced